Tgen049240.1
Basic Information
- Insect
- Timema genevievae
- Gene Symbol
- -
- Assembly
- GCA_902155825.1
- Location
- CABFWO010007637.1:5515-13693[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.1 19 7.9 2.5 3 20 226 243 224 245 0.93 2 14 0.00017 0.032 16.7 0.3 1 20 254 273 254 274 0.96 3 14 0.01 1.9 11.0 4.6 1 20 282 301 282 304 0.95 4 14 4.1e-06 0.00076 21.7 0.6 2 23 311 332 310 332 0.97 5 14 0.00015 0.029 16.8 1.9 1 23 510 532 510 532 0.96 6 14 0.015 2.8 10.5 0.2 2 21 541 560 540 561 0.93 7 14 0.0017 0.32 13.5 4.3 1 20 610 629 610 632 0.92 8 14 0.059 11 8.6 0.5 1 23 637 660 637 660 0.92 9 14 0.00015 0.028 16.8 0.6 1 23 666 688 666 688 0.96 10 14 0.019 3.6 10.2 4.9 1 23 696 718 696 718 0.98 11 14 0.0006 0.11 14.9 0.7 3 23 726 746 724 746 0.97 12 14 0.00078 0.15 14.6 0.8 1 23 752 775 752 775 0.94 13 14 0.0049 0.92 12.0 0.3 1 23 788 810 788 810 0.95 14 14 0.0012 0.22 14.0 0.0 1 23 901 923 901 923 0.98
Sequence Information
- Coding Sequence
- ATGGATGCTGAAGTGACATTGTGTGAAGAGGAACAGATTAATCCTATCGTTGGCCCGTCTTTTAGTGGGCATTGTTCAAATTCGGTACAAAACGATGCCTTGCTTAATTATGAAGGCAGTGCAATGGTTGTGTATCAAGCAGATGTTGAAATGAGTGAAGACATTTCTACTCCACAAGTGAGATGCTTAGAATTTTACCATGACAGTGAAGAACTGAATCAGGTGGACCTATCATCATTAAGTAGTTCTGCTACTTATTTAGAGAACGTTAGTGCTGAGCTTGGGACTGAAAATACTGGGACTACTTCACATGTTAACAGCATAGGAATGTATGTGGAAACTGAACCGAAGGACACCAACTCGCATTCTCATGACAAGAATAATTTCCCAAAAGCTTACCAAGATAATATTCTGAAAGTAGATATAAATGTTACTTCCAAACCTGAAGGTTCCATCACATATCGGAACAACAATGTCAAGGAGTGTGTTTTAGAGAAATGCGATCAAGAACAAACATTTTGTCACCATCGGTCTATTGTCACTGACAACGTTATGGTGAAATCTGAAAACATTGAGCCTTCGACAACTACAGATGATGAGAGTATGGCCGTGGAAGCTCTTCAGCAGCTCGGAGGTGGGGACCTACTATATTCAAACCTCAACTCGCTCCAGCATTGCTACATCTGCGGCTCAAAGTTCCACTCCAGAGACAGCTTTCAGAAGCACCTTTCCTTGTGCGCCGAGACGGGGATGGCCGCTCACACTTGCAGCGTCTGCAGGGAGACCTTTATACGCAAGTCAGACCTGGAGAACCACCTAGTGTGTCACCAGGTGGACAGGCCCTATGCCTGCAAGATATGCAGTACCTTGTTCTGCAGGAAGGCAGAGCTCCAGAATCACATGACGTGCCACAACGTCACCAGGCCTCTCAAATGCCCGCAGTGTGGGACCGATTTCCAACGGTTGTCGAGTCTCACCAATCACATGAAGATACATAACTACCCCCCGGGTAAAGCCGTTGGTTTGTTTGATCTCCGGTCAGATGGCAAACCTGTATCAATGCCGTCAACACAGGAGGGGAAATTAAAGTATGAAGAATCGTCAGCAAGTGTCAAACCTTTGCAAGGAACTTCTGTAAGTCACGTGAATACTACAGATACCAGTTTGACAAGTCGCGAGACGGAAGAAACGTCCTTTTCACAAGCTCCAAAAGTTGCAGTCCTAccaattaacaattttaacttttctatGAACCAAAGTGTGGATGAAAATTCTTTACACAACATTTGTGACTCACCCAATCAAACCTCAGGACAGCTTGTAGATTGTAGTAAAATTGAGCGTTTGAATACACAATTTGATACGCCTGACGGTGGTGATAACTTAATTTCAAAATCAGACTCAAATTTCTGTTCTGTGAAAGTCGAATCTATGCCCTATATCATGTCGCAGGGATGCCATCCTAAAGAAATGTTCTCGGCTCAAAGCCCCGAGCAAGACTTGCCAAAAGCCGAGGATAAACGCCCCCACATCTGCCGGCATTGCGGTACGGCCTTCGCCCGTCTCAAGGCCCTCCAGTCGCACGTCCGCCTGCATGAGGACAATTGGGGGGCCCCTTTGTACTGCAAGAGATGTGAGGAGAATTTCCCCGATGAAATTTCTCTTAACCGACATCAGTTGAGATGCACCGGGCCGATGACTCTGCCTCATCGGAATGTGAACGGGAGCTTGCAGCCGACTCATAACCCGACGCCGCCGACTGGACCCTATACAAAATCGTTTGAAAATGGTGTCCGTACTGCggaaacaaaaactaaattgGGGAAACATTGCTGTGAAGAATGTGAGAAGAGGTTTGCcactaaacaaaaactattcaGACACATGTGGGTGCACAGAAGAAAGCAGTACGTATGCGAGGTGTGCGGGTGCGCGGTGACGAGTCAGCAAGGTCTAGACGAGCACCGCCATGCCATGCACCCAGGCGAGAATCGACACATATGTTTCCAGTGTGGCAAGAGCTTTGTGAGCCGTCAGGGCCTCTGGGAGCACGGCAGGGTCCACGGTCGTGGACCCCCGGGGGTGTTCCATTGTCAGCAGTGCTCCAAACAGTTCACAAGCAGACaaGGGTTTCTCATTCATAACCGAACACACACGGGTGAACGCCCTTACGGGTGCAAGTTTTGCACCAAGGCCTTCCGGGACGGCGGTACACTCCGAAAGCACGAGCGGATACACACCGGAGAGCGGCCCCACGCTTGTCCCCTCTGTCACCGCGCGTTCAACCAGAAGGTGGTGCTGCGGGAACATGTGAGATGGGTGCACGCGGCCAACAAGTCCAATAACGACGTACCCCACATCTTCTCGTGTCAGCTGTGTGGCCAAACCCTCGGAGACAGAGAGGAACTGTGCGCCCATATCGTCCAACACAGTGACCAGATGGCGGCCGCCGCCAAAGCTTTGACCGCAAGTAGCGTTGAAAATCCGAATATTATCAAAAAAGAACTTGGTGCAAAAATGGTAACTTCAGAGACCACGCCGCCTTCATCAACGGAAATGTGCGCCGATATGACCGCACAAGCATCGTCGGCGACTGATTCTTACATTACATCAAAGTATTTAGTTCCTAACGGGGTGATCACGATTAATAAACCAGAAGGTGGCGTAATCTCATCGCGTATAAAGATGGAGGCCAGGGATTATGTTTGTGACATGTGTGGGGAAGGTTTTGCATTGAAGGAAGGTCTTTTGAACCATGTTTTAATTCACATTTGA
- Protein Sequence
- MDAEVTLCEEEQINPIVGPSFSGHCSNSVQNDALLNYEGSAMVVYQADVEMSEDISTPQVRCLEFYHDSEELNQVDLSSLSSSATYLENVSAELGTENTGTTSHVNSIGMYVETEPKDTNSHSHDKNNFPKAYQDNILKVDINVTSKPEGSITYRNNNVKECVLEKCDQEQTFCHHRSIVTDNVMVKSENIEPSTTTDDESMAVEALQQLGGGDLLYSNLNSLQHCYICGSKFHSRDSFQKHLSLCAETGMAAHTCSVCRETFIRKSDLENHLVCHQVDRPYACKICSTLFCRKAELQNHMTCHNVTRPLKCPQCGTDFQRLSSLTNHMKIHNYPPGKAVGLFDLRSDGKPVSMPSTQEGKLKYEESSASVKPLQGTSVSHVNTTDTSLTSRETEETSFSQAPKVAVLPINNFNFSMNQSVDENSLHNICDSPNQTSGQLVDCSKIERLNTQFDTPDGGDNLISKSDSNFCSVKVESMPYIMSQGCHPKEMFSAQSPEQDLPKAEDKRPHICRHCGTAFARLKALQSHVRLHEDNWGAPLYCKRCEENFPDEISLNRHQLRCTGPMTLPHRNVNGSLQPTHNPTPPTGPYTKSFENGVRTAETKTKLGKHCCEECEKRFATKQKLFRHMWVHRRKQYVCEVCGCAVTSQQGLDEHRHAMHPGENRHICFQCGKSFVSRQGLWEHGRVHGRGPPGVFHCQQCSKQFTSRQGFLIHNRTHTGERPYGCKFCTKAFRDGGTLRKHERIHTGERPHACPLCHRAFNQKVVLREHVRWVHAANKSNNDVPHIFSCQLCGQTLGDREELCAHIVQHSDQMAAAAKALTASSVENPNIIKKELGAKMVTSETTPPSSTEMCADMTAQASSATDSYITSKYLVPNGVITINKPEGGVISSRIKMEARDYVCDMCGEGFALKEGLLNHVLIHI*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01450856; iTF_01448848; iTF_01445054;
- 90% Identity
- -
- 80% Identity
- -