Tgen033831.1
Basic Information
- Insect
- Timema genevievae
- Gene Symbol
- -
- Assembly
- GCA_902155825.1
- Location
- CABFWO010003274.1:4582-36828[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.15 27 7.4 2.2 1 23 299 321 299 321 0.93 2 13 0.00022 0.041 16.3 1.4 1 23 326 350 326 350 0.94 3 13 0.00023 0.043 16.2 0.8 2 23 374 396 373 396 0.95 4 13 0.0011 0.21 14.0 1.3 1 23 402 425 402 425 0.94 5 13 0.0011 0.2 14.1 0.6 1 23 438 461 438 461 0.89 6 13 1.5e-06 0.00028 23.1 2.6 1 23 467 489 467 489 0.98 7 13 4.1e-05 0.0077 18.6 0.4 1 23 495 517 495 517 0.93 8 13 0.00019 0.035 16.5 2.3 1 23 523 545 523 545 0.97 9 13 3.9e-08 7.3e-06 28.1 0.9 1 23 551 573 551 573 0.99 10 13 2.6e-05 0.0048 19.2 5.8 1 23 579 601 579 601 0.97 11 13 0.99 1.9e+02 4.8 6.3 2 23 608 629 607 629 0.96 12 13 3.9e-05 0.0073 18.6 1.9 1 23 635 657 635 657 0.98 13 13 3.1e-06 0.00057 22.1 5.2 1 23 663 685 663 685 0.98
Sequence Information
- Coding Sequence
- ATGGAAGTAGTATTGTATGATTCGACAATTTGTAGATTATGTGGTGAAGAAAATGATAGTGGAGTTTTCCTGTACACTAATGAAGAGCTAGAACCTGATTTAAGTGCTTTGGTCAATAAATATCTTCCTTGCAAGATTCAAGATGATGGGAAGCTACCGAGGACCATTTGCCCCGGCTGTAACATTCAGCTGCAGGCCACAGTCCAGTTTTTTGATCTGTTGGTGGAAGGTCAAAAGAAAATCCGAGAAATGTGGAAAAGTCAGGTAGAGATGCAACGGAGATTGGAGAAGGATCGTCAGAGGTCGGAACACTCTGGGATCAGTTTACTGGTCACCACGGAGACCCCGGTGAATGCCGATGGAGAACAAGATGGCGAGGAAGAGACTACAGAGAAGCGTATTGTAATCCAGATCCTGGAGGATGGCACCTTGTACGCCCCAGATCACAAGATGACCCTGCAGATGGAGGGTCTGGAGAAACCGCGACGCAAGCGTGGCCGCCCGCCCAAGCGCCCACCTGATCCTGAGGAAGACAGGGCCAAAGAACTGGAAGAACCCTTGGAGAACCCACCAGAGGAGGAAATGGAAGAGGACGCAGATGGGCGCAAGCGACGCAGGATAAAAGTACCACAGAGATTCAAGGAGGCGGTCCAAGGTAAAGAGTTGGATCGTATCTTCAAGGAGGAAGGTTTGATAAACGAGGACGAAGATGAGGAAGGGGTGGAGGAAGAGGAAGTGCAGGAGAAGACTCCTCCACTTGAAGTTATCGCTCAGGAAGCGGAGGTGATTGGTCACTTGGAGACCCAGGAGGGGCAGGACCTAGGGGAGCTGGTGATCGTAAACCGTGGCCGCAAGAGGGGCCGGCCACGAGGCGGGAAGCGCCGGAAAGTTCGCTTTGAATGCGAGATCTGCGGCCGAGGCTTCCTCCACAAGGGTCGTTACAAGATTCACAAGACCTACCACAAAGGAGTCAAGTTTGAGTGCAGCAGCTGCAACAAGAGGTTTGTCAATCGAGAGCTATTCGAGTCTCATCAGAAAACTACGGGGCATATCGGCGAGGGTATAATCGAGGGGCTGGCAGACGGGGGGGATGGTGGGGAGATGCCAGGCTGCCGGGTGAAGTGCTGGCAGTGCGATAAAACTTTCCAGACCAAGCAGAGCTTTGAGGTTCACCAGAAAGCCATTCACGAGGGAGTTAAGCCCTTTGTTTGCGAGGTTTGTGACAGGACCTTTGCCTACCAGAACAGCCTTAAGTGCCATATGCTGGCATCACATTGTgagGACGCGAAAGGTCTGGACAAAGACAAGGGCTACCCTTGTGACATGTGTGACAAGAAGTTTAACCACCCCAGCTCGGTGGTTTACCACAAGGAAGCGGAGCACAACAACGGCCGTGTATTTGTCTGCAACAAGTGTGGGAAGGGCTTCAGACACCGCCAGTTGCTGCAGAGGCACCAGCTCGTGCACTCGGAGGACCGTCCGTATGTGTGTAAGTCGTGTGGTGCGAGCTTCAAGACTAAGGCCAACTTGCTGAACCACCAGCCCACGCACACCGGAGAAAAGAAGTATTTCTGCGAGCTTTGTGGTCAGCAGTTTGCGCATAAGACTAGTCTCACCCTCCATTATCGCTGGCACACAGGTCAGAAACCGTACAAGTGTCAGGTGTGTAACAAGAGCTTCTCCCAGAACGGAAATCTCCAGGAGCACCTGCGGATACACACTGGGGAGAAGCCCTTCTGTTGTGACTACTGCGGCCGCAAATTCACCACCTCCTCCCAGTTCAAGCTGCACGTCAAGCGGCACACGGGTGAGCGACCTTGGAAATGTGACTTCTGCGGGAAGTCGTTCCTACACAAGGACACGTGGAAGTGCCACACACGGCGTCATAAAGGCGAGCGTCCCTTCCAGTGCCACTATTGCGCCCGAGGCTTCACAGAGCAGTGGGCCCTCAAGAAGCACCTTAGACTTCACACAGGTGAAAAGCCCTATACTTGTAACACTTGCGGGAAATGTTTCGCCGACTGCTCGAACCTCGCCAAACATAAAAAGGTCCACAAGGGCAGCTGTGAGAACGAGAGCACCGCTCCAGGGGACTCTCTCGTGGACCGCACCACCGTCTGGAACATCATCCAATCCCACTTAGCCAAGGATGTTTCCGAGCAGGATGGGGCAGACTCCCAGGGAGAGGACGCGGGCCAACAGATCATCTACGTCACTTACCAAGACCCCGATGACCCTGAGGGCAAAACGTTGCATATTGTTGACTCCCAACAGAACCCACAGCACTCCGAACTGGAACAGTCCCAAGAACAGCATCAAGTGGCGCTGAGGGAGACCGAGGAGGTCGGAGAACTGGAGGGGTCGAAGGACTCTCTGGGATCTCTGCCCCACTCTCTACAGGTGATGGACGAGGAGGGTAACCCCATCCACTTCACCATGCAGGACGGTCGAGAGCTACAGATCACGACGACAGACGGTCAGTCGTTGCACGTGACCACTCTGGACGGTCAGACCATCCCCTTGCAGCTCACCACCCCGGATGGACAACCTCTTACTGCAGGCGGGCCAGAGGTTAGAGTTCATCCCTCTAACGACAACCTCATGATGGGACAGCCTTCAGATGACCTCATGATCCAGGAGTCGCACACAAACCCGAACGGGATGCTGAAAAGCGTTAAGGGAAGCGAAGGACCGGCAGGTGAACCTCTGACCGAAGGAGAACAAGCCATCGAGTTCACTACGCCCGACGGCCAGAAAGTGAGGCTTGTGACTTCTTACGGGGTGGACCCCATCACAGAGTACCTCAGCACCAACACGTAG
- Protein Sequence
- MEVVLYDSTICRLCGEENDSGVFLYTNEELEPDLSALVNKYLPCKIQDDGKLPRTICPGCNIQLQATVQFFDLLVEGQKKIREMWKSQVEMQRRLEKDRQRSEHSGISLLVTTETPVNADGEQDGEEETTEKRIVIQILEDGTLYAPDHKMTLQMEGLEKPRRKRGRPPKRPPDPEEDRAKELEEPLENPPEEEMEEDADGRKRRRIKVPQRFKEAVQGKELDRIFKEEGLINEDEDEEGVEEEEVQEKTPPLEVIAQEAEVIGHLETQEGQDLGELVIVNRGRKRGRPRGGKRRKVRFECEICGRGFLHKGRYKIHKTYHKGVKFECSSCNKRFVNRELFESHQKTTGHIGEGIIEGLADGGDGGEMPGCRVKCWQCDKTFQTKQSFEVHQKAIHEGVKPFVCEVCDRTFAYQNSLKCHMLASHCEDAKGLDKDKGYPCDMCDKKFNHPSSVVYHKEAEHNNGRVFVCNKCGKGFRHRQLLQRHQLVHSEDRPYVCKSCGASFKTKANLLNHQPTHTGEKKYFCELCGQQFAHKTSLTLHYRWHTGQKPYKCQVCNKSFSQNGNLQEHLRIHTGEKPFCCDYCGRKFTTSSQFKLHVKRHTGERPWKCDFCGKSFLHKDTWKCHTRRHKGERPFQCHYCARGFTEQWALKKHLRLHTGEKPYTCNTCGKCFADCSNLAKHKKVHKGSCENESTAPGDSLVDRTTVWNIIQSHLAKDVSEQDGADSQGEDAGQQIIYVTYQDPDDPEGKTLHIVDSQQNPQHSELEQSQEQHQVALRETEEVGELEGSKDSLGSLPHSLQVMDEEGNPIHFTMQDGRELQITTTDGQSLHVTTLDGQTIPLQLTTPDGQPLTAGGPEVRVHPSNDNLMMGQPSDDLMIQESHTNPNGMLKSVKGSEGPAGEPLTEGEQAIEFTTPDGQKVRLVTSYGVDPITEYLSTNT*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01446849;
- 90% Identity
- iTF_01450895;
- 80% Identity
- -