Basic Information

Insect: Timema genevievae
Gene Symbol: -
Assembly: GCA_902155825.1
Location: CABFWO010000774.1:149126-152706[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 0.0028 0.53 12.8 2.1 1 23 151 174 151 175 0.97

2 19 0.2 37 7.0 0.6 1 23 204 226 204 226 0.97

3 19 1.9e-06 0.00036 22.8 3.7 1 23 232 254 232 254 0.98

4 19 4.3e-05 0.008 18.5 0.7 1 23 257 279 257 279 0.98

5 19 0.005 0.93 12.0 0.7 1 23 637 659 637 659 0.96

6 19 5.1e-06 0.00095 21.4 0.8 1 23 667 689 667 689 0.97

7 19 0.91 1.7e+02 4.9 1.2 2 23 697 719 696 719 0.95

8 19 5.7e-05 0.011 18.1 0.3 2 23 752 774 751 774 0.96

9 19 1.3e-05 0.0025 20.1 3.3 1 23 787 809 787 809 0.99

10 19 0.013 2.5 10.7 0.2 3 23 818 839 816 839 0.96

11 19 3.7 6.8e+02 3.0 2.5 1 23 843 865 843 865 0.94

12 19 0.00045 0.084 15.3 1.8 1 23 871 894 871 894 0.96

13 19 0.019 3.5 10.2 5.1 3 23 899 919 898 919 0.97

14 19 0.00038 0.072 15.5 0.5 3 23 929 949 927 949 0.95

15 19 0.2 38 7.0 0.1 1 23 955 977 955 977 0.97

16 19 5.2e-06 0.00097 21.4 1.2 1 23 983 1005 983 1005 0.97

17 19 3e-05 0.0057 19.0 3.2 1 23 1011 1034 1011 1034 0.98

18 19 3.5e-06 0.00066 21.9 1.1 1 23 1040 1062 1040 1062 0.97

19 19 0.00057 0.11 15.0 1.7 1 23 1068 1091 1068 1091 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	0.0028	0.53	12.8	2.1	1	23	151	174	151	175	0.97
2	19	0.2	37	7.0	0.6	1	23	204	226	204	226	0.97
3	19	1.9e-06	0.00036	22.8	3.7	1	23	232	254	232	254	0.98
4	19	4.3e-05	0.008	18.5	0.7	1	23	257	279	257	279	0.98
5	19	0.005	0.93	12.0	0.7	1	23	637	659	637	659	0.96
6	19	5.1e-06	0.00095	21.4	0.8	1	23	667	689	667	689	0.97
7	19	0.91	1.7e+02	4.9	1.2	2	23	697	719	696	719	0.95
8	19	5.7e-05	0.011	18.1	0.3	2	23	752	774	751	774	0.96
9	19	1.3e-05	0.0025	20.1	3.3	1	23	787	809	787	809	0.99
10	19	0.013	2.5	10.7	0.2	3	23	818	839	816	839	0.96
11	19	3.7	6.8e+02	3.0	2.5	1	23	843	865	843	865	0.94
12	19	0.00045	0.084	15.3	1.8	1	23	871	894	871	894	0.96
13	19	0.019	3.5	10.2	5.1	3	23	899	919	898	919	0.97
14	19	0.00038	0.072	15.5	0.5	3	23	929	949	927	949	0.95
15	19	0.2	38	7.0	0.1	1	23	955	977	955	977	0.97
16	19	5.2e-06	0.00097	21.4	1.2	1	23	983	1005	983	1005	0.97
17	19	3e-05	0.0057	19.0	3.2	1	23	1011	1034	1011	1034	0.98
18	19	3.5e-06	0.00066	21.9	1.1	1	23	1040	1062	1040	1062	0.97
19	19	0.00057	0.11	15.0	1.7	1	23	1068	1091	1068	1091	0.95

Sequence Information

Coding Sequence: ATGTTTTCCATTTCGGATGGAAGACTGGACGACAGCAACATTCTTTTGATAATTCGCCGCTCGGCAGTCGGCCGATTCTGGCTCCGCCCACTCGACGACAAATATCGTCGGGCAACATTGTCCAGCGACTCGCGTCGGCCGATAATCGTGACACACATACCTGCATCACCACCTGAGAACCTTGTGGACCTCACGGGGTCCTCCAGTCAGTCCGACATCAAAATAGAGAGAGTCATGTCGATGGTCACCGACAATACTAATACAAACTCGAGGGATAAAGTTGCCAAGAGCACCCTGGGAGCCTCTAACAAGCAGAACACCGCCATGACCTTGGACGTGGACGTGTCCGACCCGGACGCGACAATGTACCGCTGCACCTCGTGTAGATATAAGACCCTCCACATGCTCTCGTTTGTGCAGCACCTCAAGACACACCCCAAGAAGACTTACTACAAGTGTTCAGAGTGTTCACAGCAGTTTGAGAAGCGGAGCGACGCCCAACAACACATTACAACTGTCCACCACTGCAGTGATGTTGAGTTTGACGACGACACCTCCGCACCCGTCAAGAAAGTCCCAGAGGCACCCCCGACCCAGAAAAGAAAGGTGTTTGAGTGTGACATCTGCAGCTACCGCGACACAGACAGAGACCAGTTTGACAAACACTTGTTGTCTCACACCCAACCAACATTTTACGAGTGCAGCATTTGTTCTAAGAGATTTAAAAGCAAGCAGTACTTGCAGAAGCACATGAAGAATCATAAGATATACAAATGTGGGATCTGCGGTTTAACATTCAGGGTGAAGCTGAACCTTCTAAAACACTTCAAGGTTCACAAGAGTGATGAGCCAGCCGAGGATCCTCCTATAGAGGAGACCACATCATCCTCGCTGGTtgaggagaaggaagaggaaaagGAAAACATGGAGCAGGAGGAGGCATCAACACCAAAACGTTTGAAGCTTCATGAAGATTACGACCGGGTGGAGCAGATGCTGGAAATGATGCATTCCGGCGCCTCTGTGCTTGAAGACCAGGAGCCGAAACAGACCGATGGTGATACTATGGAGCAATCTGATGATGTGGACAAAGTTGTAGAGAGTATCTCGGAACACTTGAACGGTGAGAAAGAGGAAGAAAACTTGGATGCTGGAGAAAGTTTGGTTGAGCACGAACCGAAGACGGTCGATGACTCTCTAGAAAGTGCCGAAGAACGTGTTGAAGACGAGAAAGAGGAGGATAGCTCAGATGATCAAACTGTTACTGAGAAAAGATTTGTTAGCTTGGAAGAAGTGAAAAATATTGCAGACAGTTTTGACAGTTTGGACGACGTGGCTGAGAGCTCTGAGTTGATCCACCAGGGTGATCAAGAtggtttgaatgacaaactagAAAATGGCACCATCAAATTGGAGGAACCGAAGATGGAACTGGACGTTGATGTGAATAAAGAGGCAGACAAGATAGTAAGTGAAGCTCTTGGAGTGGATTTGAACGAATATATCAGTAATGACATGAACATGGACATTAGTGCATCGTCTGACAAACCAGAGAACAGCCTGCCCTCGCTAGTGTCTGAAAACTCTGGGTCACTACCAGAAATGGACGATAACACAAGGGAGGAGGCCATAGAGAAGGACCACCTCACAGATGTCAATGAATCAATTACAGGTATGACACAATCACCAGTTATTAATGCTAGTCAGGAAATGAAGTCAGAACTAGTTGACAATATGTTTGATGAACTTTTCTGGCACTGTCCCAATGAGTCATCTTTACCATTTCAGGTTGATGCCGACGGCCCTGCCCCGGATTTTGAGGTGGAGATACATGAAACTGGTCTTCCGTCTCTCTCCACCGCTGCAGAGCAACACACCCCGAACCTGGccaccgcaaaaaaaaaagtttacctttGTTCGGTGTGTGGGCTGAGGTCACGCTCAGAAAATCAGATCCGGAGGCATCTAAGGAGCCACATCGCACTGAGGAAGAAAAGTTTCGTATGCCGTGTATGCAGCAAGATTTTCACCACCCAGGGTAACTTGACCCGTCATTTAGTCAAACATTCACCTGAGAACAAGAGTGTCCCGTGTGACGTGTGTGATGGTTTATTCCATGATAGGCTTCACTTAAAAGAACACACGGATACCACCCACTCGGGAAGACACAAGTGCTCGTTTTGCAATACTATACTAACTAGCAGGAAAGCTCGCTGGTTTCACGAGAAGACTCATCCTGAGCGGCTCGAGCAAAAGTGTGACGATTGCGGAGAGGTATTTGAAACCAAGGTGAAACTCAAGATTCACAAGGAGACCGTCCATGCTGATGCCACGTTTGAGCTCACTGAGGGTAAGATTTACAAGTGCCACCTATGTGGTAAGATTGTATCAACATACTTTAACCTCAGGAGGCACCTGCAGAGTCATAAGGGTGATGTAGGGCAGACTAATTGCAACATATGTCTCACAGGGTTTAAAGACGGCTCGCTCCTGCAGCTGCACCTCATAACTATGCACCCCAATAACTACCACTGTCCGTTCTGCCTTCTAGTGTTTCCCAGTAAGCAACTGTGTAAGATTCATGAGGCAACCCATCCTGAGAAGCTATCCCACAGGTGCGTTGATTGTGACAAGCGCTTTGCGACGACTGAGCGACTAGAACGGCACAAACAAGTGATGCATCGAGACCCCCACTGCAAGTACTGTGGGAGGTGCTATGGAGATATGAAAAAGTTGTTTGCTCATGAGCGTCGGCACGAGAGGTACAAAAAGATGTCTTTGGACTGTACACAATGCGATAAAACATTTAAGACCCCCACAGGACTCAAGTTCCACATGGCTGTGCACACGGGAGAATACGCATTCTACTGCGAGATATGTGGCCAAGGCAGGCATTCTGAGGTGGTTCTTGCGGAGCACATGGCAACTCACACTAAAGAGATCCGTTACATTTGTGACTATTGCGGTAAGAAGTTCTCTTCCAACAGCACCTACCGGATACACCGCCTCTGGCACGAGAACCCCTTCCCTTATAAATGCACCACATGTGGGAAGCGCTTCAAACACACGTCGGTACTTGCTGTCCATAGACGACGGGTGCACACAGGTGAGCGCCCTCACAAGTGCCCTTATTGCCCATTATCGTTCACTGTGTCAAGCACATTACGCAAGCACATTATCTTACACACTCAGCAGTTCCCTCACAACTGTACTTCCTGTGGGAAGGGGTACACTACTAGGACTAAGTTGGCTCGCCATCTTGCCAAGGTTCACAACGACAACGAAATGCTCAACAATCTTAGTCACCACTATGAGTACAAGATGGCACTGCAGCCTAGTGAGGTCTCACCCTTGGTGGAACTACTTGAACGCTCTGGGAAATGA
Protein Sequence: MFSISDGRLDDSNILLIIRRSAVGRFWLRPLDDKYRRATLSSDSRRPIIVTHIPASPPENLVDLTGSSSQSDIKIERVMSMVTDNTNTNSRDKVAKSTLGASNKQNTAMTLDVDVSDPDATMYRCTSCRYKTLHMLSFVQHLKTHPKKTYYKCSECSQQFEKRSDAQQHITTVHHCSDVEFDDDTSAPVKKVPEAPPTQKRKVFECDICSYRDTDRDQFDKHLLSHTQPTFYECSICSKRFKSKQYLQKHMKNHKIYKCGICGLTFRVKLNLLKHFKVHKSDEPAEDPPIEETTSSSLVEEKEEEKENMEQEEASTPKRLKLHEDYDRVEQMLEMMHSGASVLEDQEPKQTDGDTMEQSDDVDKVVESISEHLNGEKEEENLDAGESLVEHEPKTVDDSLESAEERVEDEKEEDSSDDQTVTEKRFVSLEEVKNIADSFDSLDDVAESSELIHQGDQDGLNDKLENGTIKLEEPKMELDVDVNKEADKIVSEALGVDLNEYISNDMNMDISASSDKPENSLPSLVSENSGSLPEMDDNTREEAIEKDHLTDVNESITGMTQSPVINASQEMKSELVDNMFDELFWHCPNESSLPFQVDADGPAPDFEVEIHETGLPSLSTAAEQHTPNLATAKKKVYLCSVCGLRSRSENQIRRHLRSHIALRKKSFVCRVCSKIFTTQGNLTRHLVKHSPENKSVPCDVCDGLFHDRLHLKEHTDTTHSGRHKCSFCNTILTSRKARWFHEKTHPERLEQKCDDCGEVFETKVKLKIHKETVHADATFELTEGKIYKCHLCGKIVSTYFNLRRHLQSHKGDVGQTNCNICLTGFKDGSLLQLHLITMHPNNYHCPFCLLVFPSKQLCKIHEATHPEKLSHRCVDCDKRFATTERLERHKQVMHRDPHCKYCGRCYGDMKKLFAHERRHERYKKMSLDCTQCDKTFKTPTGLKFHMAVHTGEYAFYCEICGQGRHSEVVLAEHMATHTKEIRYICDYCGKKFSSNSTYRIHRLWHENPFPYKCTTCGKRFKHTSVLAVHRRRVHTGERPHKCPYCPLSFTVSSTLRKHIILHTQQFPHNCTSCGKGYTTRTKLARHLAKVHNDNEMLNNLSHHYEYKMALQPSEVSPLVELLERSGK*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01449831;
90% Identity: iTF_01445018;
80% Identity: -