Tgen012525.1
Basic Information
- Insect
- Timema genevievae
- Gene Symbol
- -
- Assembly
- GCA_902155825.1
- Location
- CABFWO010000704.1:69741-80090[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 8.3e-05 0.016 17.6 1.2 1 23 137 159 137 159 0.98 2 14 2.4e-05 0.0045 19.3 3.4 1 23 165 187 165 187 0.98 3 14 0.0058 1.1 11.8 1.7 2 23 195 216 194 216 0.98 4 14 2e-06 0.00038 22.7 0.4 2 23 223 244 223 244 0.98 5 14 3.2e-06 0.0006 22.1 3.1 1 23 249 271 249 271 0.98 6 14 0.0011 0.21 14.1 0.6 1 23 311 333 311 333 0.97 7 14 0.00026 0.048 16.1 0.4 2 23 340 361 339 361 0.94 8 14 1e-05 0.0019 20.5 4.0 2 23 368 389 367 389 0.97 9 14 0.00033 0.062 15.7 5.8 1 23 395 417 395 417 0.97 10 14 0.002 0.37 13.3 1.3 1 23 425 447 425 447 0.98 11 14 1.1e-05 0.0021 20.3 0.5 2 23 454 475 453 475 0.96 12 14 5.6e-08 1.1e-05 27.6 0.6 1 23 481 503 481 503 0.98 13 14 0.0008 0.15 14.5 5.5 1 23 509 531 509 531 0.96 14 14 1.9e-05 0.0036 19.6 0.2 1 23 537 559 537 559 0.98
Sequence Information
- Coding Sequence
- ATGGAGGAAGGTGTGATGCCAGATATCGAGTTGGGGGATGTTATATATCCTGAGCTGATCATGAAAGTGGAAGTCGCAGACAAAGACTCAATGACGaGCCCCCCAGAAGCAGTCAGCAACTGGGACATTGTCTGGAAAGATGACGGACACGCAGAGATTGTGTTGAAGCAAGAGGTGATTAATGACGACATCAGAGAATCTGACACTTTGGCCGCCACGATCCATCTCCTTTCTGAAGATTTCGACATTTCCCTGTCTACATTTTCATCCAATGGTGATGAGAGCAGTGCCTCACTAATAGACCCTGTTTCAAGCGAAGTATTTCAAGACAAGGTGCACCGGGTTAACAATCCACACAAAGTGAAGGGCCCCACCAAGACACGCCAGCTCCATATATCACCACGAAAGTTCTCCTGTGCTATATGCAACAAGAGCTACATGTCAAAGAGGGGCTTAAAAGAGCACCAGATGAAGCACTCTGGACTGAGGCCTTTCTCTTGTGACCAGTGTGGTCGCTCGTTCACCACGAGGAGGCTGCTGTGCTCTCACAGGCTGGTGCACGCGGCCGTACGTTGCGCAGTTCAGTGTGGCACGTGTCACAAGACGTATCTGAGCGCGCAAGCCCTGCGGACACACCAGCAGACCCACACGGGGCGCCTCCGGGAGCGTTGTCCGGTGTGCGAGGCCACCTTCACTCAGAGGGGCTCCCTACAGCGCCACATGATGTCCCACGGGGAGGGTGGCTACCCCTGCCCCCATTGCAACAAGCGTTACTCCAGGAATGATAAGCTTCAGGACCACTTGAGGTTCCACAACGGGGACACCAGGGTGCGATGCCGCTTCTGCCGGGCTTATTTCCCTGACCATGAGGCTCGCAAACAACATTACATTGACAAGCCTGGCCACGTCCGCCAGGAGAATGTCCAGGTGTTTGAGTGCCAGGACTGCGGCAAGAAGATCCGGGGCAAGAGAAACTATGAGACCCATGTACTGAACCATCGCGGGGAGAAGAACTTTCTTTGCGACGCGTGCGGTCAGAGGTTCGTCTCCTCTAAGCTCCTCAAATCTCACCAGGCGACTCACGCGACTCGCTCGCCGGTCGAGTGTCCGCTTTGCGAGAAATCTTTCTGCCACAAGACCAGTCTTCGGACACACCTTCGGATCCACAGGGGTGTGAAGATGTTCAAGTGTCACCTCTGCGAGAAGGAATTCAGTCAGAACTGTACACTTCGCAAGCACGTGCTTCTGCACCTCGGGAAGCCTATACACAAGTACGAGTGTCACATCTGCTCAAAGGGATTCCTGGGCCGTGACAAGATGAAAAGACACATGATAGTTCACACGGGTGAGCGGCCGGTCCAATGTGAACTGTGTCAGCGCAGCTTCGCTGACAAAAAGAGTCTGAAGACCCACATGCTGGCTCACACCGGGGAAATGCCCTATGAATGCAATGACTGTGGCCGCAAGTTTCGACAGCGAGGGAACCTCATTAAGCACATACAGCTCCATGCCGGGGAACTTCCGTTCGAGTGCCACGTATGCAAACATCGGTTCTCGCGCAAGGACAAGCTGAAACTCCATGAGGGCACACACCAAGGTCTGAGGCCCTATCCTTGTCCTGTGTGTGGCCGAGGATTCACTCAAAGTGGCTCTCGAAAACTACACCTGCGTCTTCATTCGGCCCGGGATCTGCGTCGGTATGGGCTGATAAAGACATCCAATGGGGCTGGTGAAAACTACCAGCAGAGCAATACAGTGGGCTGGGGAGAACTACCAGCAGATGAACACACCGGACTGGTGAGAACCATCAGCATGGTGATATTATGGGCTGATGAGAGCTACCAGCAGAGGAACACAGTGGGCTGGGTAAGAACTACCAGCATAGTAATATTATGGGCTGATGAGAGCTACCAGCAGATGAACACAGTGTACTGGGGAGAACTACCGACATTGGAACACCATGGGCTGGTGAGAACTACCAGCACAGGAAGATGTGGCATCATTCTGTGCATTTGCGACTTTATTATGGACCGCAAACTCAAGCAGAGAGCCAACATCAAATTCTACGTCTTACTCAGAAAATCTGTAACGGAGACCTTCCAAATGATGCAGCAGGCTTACGGCAATGAAGCTACGAGCCGTCCTGTATGTTTTGAGTGGGACTCGCCCTTCAGAAGCTGCAGATTGCTCAATATTCACAGTGGAAGAACCCCAGATCCCCAAGATCGAATTTCCGGGTTTGTGCTCATGGAAGGTCGCCCAGACCTCTCCTGA
- Protein Sequence
- MEEGVMPDIELGDVIYPELIMKVEVADKDSMTSPPEAVSNWDIVWKDDGHAEIVLKQEVINDDIRESDTLAATIHLLSEDFDISLSTFSSNGDESSASLIDPVSSEVFQDKVHRVNNPHKVKGPTKTRQLHISPRKFSCAICNKSYMSKRGLKEHQMKHSGLRPFSCDQCGRSFTTRRLLCSHRLVHAAVRCAVQCGTCHKTYLSAQALRTHQQTHTGRLRERCPVCEATFTQRGSLQRHMMSHGEGGYPCPHCNKRYSRNDKLQDHLRFHNGDTRVRCRFCRAYFPDHEARKQHYIDKPGHVRQENVQVFECQDCGKKIRGKRNYETHVLNHRGEKNFLCDACGQRFVSSKLLKSHQATHATRSPVECPLCEKSFCHKTSLRTHLRIHRGVKMFKCHLCEKEFSQNCTLRKHVLLHLGKPIHKYECHICSKGFLGRDKMKRHMIVHTGERPVQCELCQRSFADKKSLKTHMLAHTGEMPYECNDCGRKFRQRGNLIKHIQLHAGELPFECHVCKHRFSRKDKLKLHEGTHQGLRPYPCPVCGRGFTQSGSRKLHLRLHSARDLRRYGLIKTSNGAGENYQQSNTVGWGELPADEHTGLVRTISMVILWADESYQQRNTVGWVRTTSIVILWADESYQQMNTVYWGELPTLEHHGLVRTTSTGRCGIILCICDFIMDRKLKQRANIKFYVLLRKSVTETFQMMQQAYGNEATSRPVCFEWDSPFRSCRLLNIHSGRTPDPQDRISGFVLMEGRPDLS*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01446823;
- 90% Identity
- iTF_01449827;
- 80% Identity
- -