Basic Information

Insect: Timema genevievae
Gene Symbol: -
Assembly: GCA_902155825.1
Location: CABFWO010002107.1:113562-120334[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 32 6.1 1.1e+03 2.3 0.8 2 23 23 43 23 43 0.88

2 32 9.3e-05 0.017 17.5 1.9 1 23 49 71 49 71 0.97

3 32 0.063 12 8.6 0.9 2 23 78 99 77 99 0.97

4 32 1.8e-06 0.00035 22.8 2.2 1 23 105 127 105 127 0.98

5 32 0.00011 0.021 17.2 1.4 1 23 133 155 133 155 0.98

6 32 8.6e-05 0.016 17.6 0.9 1 23 161 183 161 183 0.98

7 32 4e-06 0.00075 21.8 1.3 1 23 189 212 189 212 0.96

8 32 0.00032 0.059 15.8 0.3 1 23 222 244 222 244 0.95

9 32 2.7e-05 0.005 19.2 0.1 1 23 251 273 251 273 0.95

10 32 8.3e-06 0.0016 20.8 3.3 1 23 279 301 279 301 0.96

11 32 8.9e-06 0.0017 20.7 0.4 1 21 307 327 307 328 0.95

12 32 0.00019 0.036 16.5 2.2 1 23 382 404 382 404 0.97

13 32 5.3e-05 0.0099 18.2 3.5 2 23 411 432 410 432 0.98

14 32 2.3e-05 0.0043 19.4 3.4 1 23 438 460 438 460 0.98

15 32 0.0043 0.8 12.2 2.3 1 23 466 488 466 488 0.98

16 32 0.0013 0.25 13.8 0.5 1 23 494 516 494 516 0.96

17 32 0.0014 0.26 13.8 2.1 1 23 522 545 522 545 0.96

18 32 0.00075 0.14 14.6 2.7 1 23 555 577 555 577 0.95

19 32 2.5e-06 0.00046 22.4 0.5 3 23 584 604 583 604 0.99

20 32 0.00032 0.059 15.8 0.6 1 23 610 632 610 632 0.98

21 32 0.00062 0.12 14.9 0.2 1 21 638 658 638 659 0.94

22 32 0.00016 0.029 16.8 1.4 2 23 711 732 710 732 0.96

23 32 0.0015 0.28 13.7 5.1 3 23 739 759 738 759 0.98

24 32 0.0018 0.34 13.4 1.0 1 23 765 787 765 787 0.98

25 32 0.00027 0.051 16.0 0.8 1 23 793 815 793 815 0.97

26 32 0.00016 0.031 16.7 1.4 1 23 821 843 821 843 0.97

27 32 0.00012 0.023 17.1 4.4 1 23 849 871 849 872 0.96

28 32 1.4e-05 0.0026 20.1 0.3 1 23 882 904 882 904 0.96

29 32 0.0002 0.037 16.4 0.3 1 23 911 933 911 933 0.96

30 32 1.2e-07 2.3e-05 26.5 1.6 1 23 939 961 939 961 0.98

31 32 1.6e-06 0.00031 23.0 2.0 1 23 967 989 967 989 0.98

32 32 4.4e-06 0.00081 21.7 1.1 1 23 995 1017 995 1017 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	32	6.1	1.1e+03	2.3	0.8	2	23	23	43	23	43	0.88
2	32	9.3e-05	0.017	17.5	1.9	1	23	49	71	49	71	0.97
3	32	0.063	12	8.6	0.9	2	23	78	99	77	99	0.97
4	32	1.8e-06	0.00035	22.8	2.2	1	23	105	127	105	127	0.98
5	32	0.00011	0.021	17.2	1.4	1	23	133	155	133	155	0.98
6	32	8.6e-05	0.016	17.6	0.9	1	23	161	183	161	183	0.98
7	32	4e-06	0.00075	21.8	1.3	1	23	189	212	189	212	0.96
8	32	0.00032	0.059	15.8	0.3	1	23	222	244	222	244	0.95
9	32	2.7e-05	0.005	19.2	0.1	1	23	251	273	251	273	0.95
10	32	8.3e-06	0.0016	20.8	3.3	1	23	279	301	279	301	0.96
11	32	8.9e-06	0.0017	20.7	0.4	1	21	307	327	307	328	0.95
12	32	0.00019	0.036	16.5	2.2	1	23	382	404	382	404	0.97
13	32	5.3e-05	0.0099	18.2	3.5	2	23	411	432	410	432	0.98
14	32	2.3e-05	0.0043	19.4	3.4	1	23	438	460	438	460	0.98
15	32	0.0043	0.8	12.2	2.3	1	23	466	488	466	488	0.98
16	32	0.0013	0.25	13.8	0.5	1	23	494	516	494	516	0.96
17	32	0.0014	0.26	13.8	2.1	1	23	522	545	522	545	0.96
18	32	0.00075	0.14	14.6	2.7	1	23	555	577	555	577	0.95
19	32	2.5e-06	0.00046	22.4	0.5	3	23	584	604	583	604	0.99
20	32	0.00032	0.059	15.8	0.6	1	23	610	632	610	632	0.98
21	32	0.00062	0.12	14.9	0.2	1	21	638	658	638	659	0.94
22	32	0.00016	0.029	16.8	1.4	2	23	711	732	710	732	0.96
23	32	0.0015	0.28	13.7	5.1	3	23	739	759	738	759	0.98
24	32	0.0018	0.34	13.4	1.0	1	23	765	787	765	787	0.98
25	32	0.00027	0.051	16.0	0.8	1	23	793	815	793	815	0.97
26	32	0.00016	0.031	16.7	1.4	1	23	821	843	821	843	0.97
27	32	0.00012	0.023	17.1	4.4	1	23	849	871	849	872	0.96
28	32	1.4e-05	0.0026	20.1	0.3	1	23	882	904	882	904	0.96
29	32	0.0002	0.037	16.4	0.3	1	23	911	933	911	933	0.96
30	32	1.2e-07	2.3e-05	26.5	1.6	1	23	939	961	939	961	0.98
31	32	1.6e-06	0.00031	23.0	2.0	1	23	967	989	967	989	0.98
32	32	4.4e-06	0.00081	21.7	1.1	1	23	995	1017	995	1017	0.98

Sequence Information

Coding Sequence: ATGGCTCCCCGAAAGAATTGTGTAGCTGTCCCTTCGAGCAGCATGAAAGAGGATAAATCATCAGAACAATGCGACTTGTGCGGCGAGACGTTGACGGCCCGACGCATGGTCACTCACAAGAAGAAGCACAGCCTCGTCGGCCCTCACGTTTGCTCGGTCTGTGGGAAGATGTTCAACACCGAGTCGAACCTGTACTTCCACGTCAGGACGCACACCGTCTCGATAGCCATCAAGTGCGGGCTCTGCGACGCCGTGTGTCTGTCTGAAAAACTATTGAGAAGTCACATGAAGACCCACACTAAAGACAGACCTTACAAATGTGAGGTTTGTGACAAAACTTACAAGAGATCCTACGAGCTgcttaaacacaaaaaaatacacACGGGCGTAAAAAACTTCAAGTGTAATATTTGTGACTACGTGACGACTTACAAAGCTTACTtagagattcataaaaaaagacacATGGGTGATTTCAAGTATCACTGTGAAATTTGCGGTAAAGGCTACTACACTAACACGGCGTTAGAAAGTCACAAAAACGTTCACACTGGGGATAAACCTTATCAGTGCTCCATCTGTGGTAAATCGTTTATATACAAGTACAACATGATGGCTCATAAAAAACAGCTTCATCCTGATTCCGATTACGGCGTCACGAGCTATGTGTGTCTCATCTGCAACAAGTCGTTTGCTTACAAGAAGTCCCTCCTGCTGCACAATGCGGTTCATTCCGGCGAGAACCAGTCTTTCCTCTGCGACGTCTGCGGGAAAGCTCTGACTAGCAACGCGTCGCTCCAGGCCCACAGGCGTATCCACACGGGGGAGAGACCGCATGCGTGCCAGACGTGTAACAAGGCGTTCAGTAAACGTAGTACTCTACGCATTCACCTCCGGACTCATACGGGAGAGAGGCCGTACTATTGTAATGAGTGCGGCAAGACGTTCACCCAACGGCCGTCGCTTGTTGTTCATAAGAGGTCTATTTCTGTCAACACGCGCCTTAGAAAAAGAAGAACTATAATTCAAACAGATCAGAATAACACCTTGAGAAATACGTCGGAACTATCCAAGCATCTCACTGACTTCGACCGCAAGGAACCAAAACAATCTCGCAAGAAACTCCAAAAAACGAGTGTGTATCATTCGTGCAATGTGTGTGGTAAAGTGTTCAACAACCTTAGCACACTCTCTTTCCATCTGCGTTCGCATACCACGccagaattaataaaatgtgaatattgCGCCAAgactttcaaaaaaaataagCGCCTCAAGAGCCACATGAAGACCCACACGACAGAAAGGCCGTATAAATGTGAGCTCTGTAACAAGACTTATAAGCGCTCGTTTGAGCTGACGAGCCACAAGAGACTTCACGAGGGGGTGAAAAGTTTCAAGTGTGACATGTGCGAGTATGCGACAGTGTACAGGGCTCATCTGGAGAGCCACAAGAAGCGGCACACTGGGGACTTTAAATACCACTGCGAGATTTGCGGAAAAGGGTACTACACAAACACGGGACTTGAAGGTCATAAGAACGCTCACAAAGGCGAAAGACCGTACCAGTGCGCAGTGTGCGGTAAGTCCTTCCTCCACAAATACAACATGCTTGCGCACAAGAAACAGCTGCACCCCGACTCGGACCAAATCGTCAAGACGCACGACTGCACCATCTGCCAGAAGAGTTTCAACTACAGGAAGACTCTCCTCTCTCACGTGGCCAGGCACATGGGCCAGAAGTCGCTCTGTGATATCTGCGGCAAAGCGTTTGTGAACAACACGTCGCTGCAGTCTCACCGACGGATGCACACCGGCGAGCGGCCTTTCAGGTGCGAGACGTGTGGCAAGACCTTCGGCAAGAGGGCCATCCTGCGTGTTCATGAGCGGACACACACCGGGGAGAAACCGTACTCGTGCGAGGTTTGTGGGAAGTGTTTCGCTCAGCGGCCCCCCTTGGTCATACACAAGAGGTTACCAAGCGAAACTGCATCTGGTCAGACTGCGAGGTCTGACTGGAGTTCATCGATCCTCTCGACAAGACTTGGTCTGAGAGTTATGTGGTCCGGAGTTTCTCTAGCCAAGCAGCAAGAGAACGCGGACGGCGGGTCTCGGAACGGCTCTAAACAGGAGTGTCAGTCCTGCAACAAGGCGTTCAACAACAGGACGAAACTAGTGAGGCACTTACGAGAGCACGAATCCAAAGATAAGATCTGTAAGATATGCAGGAAGACTTTCTTCGGTCACAAAAAGTTGAGGAACCACATGCGGTCGCATTTGAAAGAAAGGCCGTTTGTTTGCGACAGATGCAGTAGGGCGTACAAGACCCAATTCGAGCTTAATGGGCACAAGAAGATACACACTGCAGAGAAGAGTCACGTGTGTGACGTGTGTGGGTATGCCACCATCTACAAGGCCTATTTGAAGGTCCATCAGAAAAGACACATGCGCCAGTTTAGGTTTAACTGCGACATTTGCGGGAAAGGGTACTACACAAACTGTGAGCTGCAGATCCATAAAAATGTCCACACGGGTGAGAAACCGTTCCAATGTGATGCGTGCGGGAAGGCGTACATACACAAGCACTATTTGGTCGCTCACCAGCGCTCGCACCATCCGGAACTGCAGGACGACATGACGCCTTACTCATGCGAGATCTGCGGGAAAGTGTTTGCGTACAAAAAGAGTCTGATGATGCACACCAGCGCTCATATGGGGGAGAACCAAACCTACCTCTGCGACCTGTGTGGTAAGGCCATGACGAGCAACGCGTCGCTCAAGATTCACAGGAGGACCCATACAGGGGAGAGGCCGTTTGTGTGCGACTCTTGCGGTAAGAGTTTCAATCGCAGGAATAATTTGCGAATCCACCAGCGGACTCACACCGGCGAGAAACCGTATTCGTGTGATCAGTGCGACAAGACTTTCACACAACGCTCGACGTTGGTGATTCACAGGCGGTACCACACGGGGCAGAGGCCTTACGTGTGTCAGCTGTGCGGCAAGGACTTTGTCTCTAAGACGCTGTTGAGGACCCATCAAAAGAGTCACGGACCTTAG
Protein Sequence: MAPRKNCVAVPSSSMKEDKSSEQCDLCGETLTARRMVTHKKKHSLVGPHVCSVCGKMFNTESNLYFHVRTHTVSIAIKCGLCDAVCLSEKLLRSHMKTHTKDRPYKCEVCDKTYKRSYELLKHKKIHTGVKNFKCNICDYVTTYKAYLEIHKKRHMGDFKYHCEICGKGYYTNTALESHKNVHTGDKPYQCSICGKSFIYKYNMMAHKKQLHPDSDYGVTSYVCLICNKSFAYKKSLLLHNAVHSGENQSFLCDVCGKALTSNASLQAHRRIHTGERPHACQTCNKAFSKRSTLRIHLRTHTGERPYYCNECGKTFTQRPSLVVHKRSISVNTRLRKRRTIIQTDQNNTLRNTSELSKHLTDFDRKEPKQSRKKLQKTSVYHSCNVCGKVFNNLSTLSFHLRSHTTPELIKCEYCAKTFKKNKRLKSHMKTHTTERPYKCELCNKTYKRSFELTSHKRLHEGVKSFKCDMCEYATVYRAHLESHKKRHTGDFKYHCEICGKGYYTNTGLEGHKNAHKGERPYQCAVCGKSFLHKYNMLAHKKQLHPDSDQIVKTHDCTICQKSFNYRKTLLSHVARHMGQKSLCDICGKAFVNNTSLQSHRRMHTGERPFRCETCGKTFGKRAILRVHERTHTGEKPYSCEVCGKCFAQRPPLVIHKRLPSETASGQTARSDWSSSILSTRLGLRVMWSGVSLAKQQENADGGSRNGSKQECQSCNKAFNNRTKLVRHLREHESKDKICKICRKTFFGHKKLRNHMRSHLKERPFVCDRCSRAYKTQFELNGHKKIHTAEKSHVCDVCGYATIYKAYLKVHQKRHMRQFRFNCDICGKGYYTNCELQIHKNVHTGEKPFQCDACGKAYIHKHYLVAHQRSHHPELQDDMTPYSCEICGKVFAYKKSLMMHTSAHMGENQTYLCDLCGKAMTSNASLKIHRRTHTGERPFVCDSCGKSFNRRNNLRIHQRTHTGEKPYSCDQCDKTFTQRSTLVIHRRYHTGQRPYVCQLCGKDFVSKTLLRTHQKSHGP*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01448777;
90% Identity: iTF_01444979;
80% Identity: -