Basic Information

Insect: Timema douglasi
Gene Symbol: lrrfip2
Assembly: GCA_901482245.1
Location: CABEEJ010006202.1:20361-41586[-]

Transcription Factor Domain

TF Family: LRRFIP
Domain: LRRFIP domain
PFAM: PF09738
TF Group: Unclassified Structure
Description: LRRFIP1 is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'- AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA [1]. LRRFIP2 may function as activator of the canonical Wnt signalling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin [2].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.73 2.3e+04 -3.3 0.4 256 286 279 309 253 320 0.69

2 3 4e-113 1.3e-108 365.2 28.2 1 300 537 843 537 843 0.90

3 3 0.0009 28 6.2 3.9 120 173 841 894 840 900 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.73	2.3e+04	-3.3	0.4	256	286	279	309	253	320	0.69
2	3	4e-113	1.3e-108	365.2	28.2	1	300	537	843	537	843	0.90
3	3	0.0009	28	6.2	3.9	120	173	841	894	840	900	0.95

Sequence Information

Coding Sequence: ATGGAAGATGCCGACGAATGTTGCTTCTACGACGCCGTCAGTGAGATACCCCTGAGCAAGCCGAGGATGGGCAACACCGCCGGCGCGGAGGGCACCAAAGGGGGCGGACGCCCAGGTCTCTCCGACGAGTTCCCCATAGTTCCGGTGATTGACCCGCGACAAGATGACAGTGACGACACCTCAAGTAGTGATCCCGAGATTAGATCCGCTCCAATCGATAGCGATAAGGAAAGTTCGACGTCGCTCAGTGATCAATCAGATCTGGACGAAAGAGACGATTCGGGCAGACCGTCGATGGCGGTTTCTCGGAGAGACCAGCGCTGTACAGAGGCGTCCGTCGGCGCCGACAGTTCGGGTGAAGAGGACGCCGGTGTCGCGACCTTTGACGACGAGGGCTCGCTCAGGGTGGACCGTGCTGTGGCCAAGGGGGTTGACCTGGGTGTGAATCTGCCGGACACGTTCGGGGAGAGTACGACTGAAGACTGTGAGGTCCAGAGTGTAGATGACCCCGTAGCCGAGGAAAAGATTGTACGCAACCTTCGTAAGGATGTGCTGGCCACGCCCCCCAAGAATGAGGAGCCTGACGGTGAAGTCTCGGACGTGAGTTCCTCGGCCCTTGGAGACGTCCCGCGGTCAAGTCCTGACGGTGACAAGTCCTCTGTATCCACCGAGGAAGATAATTTAGTGTCCAAAAACAACGGGAAAACCGTTGAGGACACTCTGTTGGCCGCTGAAAGTGGTTGTGATGGGGCTGATTCCCAGGATAGTAGGAAGTGTCTTGATGAGGCACCCTCTGAAGAAAGTGCTAACCAAGTTGGAAGTTCTGTGATTGACAATAGTGCTTCAGGAAGTGGATCCAGTAAGAAGGTGGACATTGGAAATGATGTCACTGACATCAGCAAAGAGGAAGAGAGGTTAATTTCTAAAGTAGAGGATAAAAAGGAAGAAGATATTGATAAGATTCCAAAGAACAAGGATATAGTTGGTGAATTAAAGGATGTAAAGGAGGAAGATGGGAAGCAAAATGATATTGTTGGTGAATTAGGGGATTTAAAGGTGGAAGATGGgaagaaaaatgaaattgttgGGGAATTAGGGGATTTAAAGGGGGAAGATCGGAAGAAAAATGATCTGGTTGGTGAACTAGAGGATATAaaggaggaagaggggaagaaAAATGATATTGTTGGTGAATTAGGGGCTGAAAAGGGGGAAGATGAGAAGAAAAATGATATTGTTGGGGAATTAGGAGGTGTAAAGGGGGAAGATGGGAAGAAAAAGGACGTGGTTGGTGAATTAGGGTCTGATAATGATGATAACAGGGGTGTCAAAAGAGTAGAAAATGTGCCAGGTAATCTATTTTGGGAGGAAAGCAAGAAAGGGAAAGAAGACACCGCCGACATCAATGGAATGAAAGAGGATGCAATTGATAAAGCTGTGGATATAAATGATGGTGATTATACTACAGAAGATAGTGATGGCTATGATCTTGACGACGATGAAGATATCAATAACAAATACATAAGTAAAGGGAATGTGGTCGATGAAACAGAGAACGAAGAAGATGCCGACTACCTGAATAATTTTCTCGGGAAAAGCAATGACCAAGCAGAGGCCCGCCTTGCAGCGAGGAGGCAGGCGAGGGCAGAGGCCCGGGAGATACGCATGCGGGAACTCGAGAGGCAACAGAAGGAGATTGAGGAGAACACCAACAAGAGTTATGACTCCTTCACCGCAGAGCCAGGAAATAGGACGCCCCGTGTGGCCACCTCCGTCAACCGCAGCAGCTCGCTGCTCTCTGGTGGAGGTAACAACAGTTACCACTCGAGTCGGCGCAGCTCTGAGGACTCGCTGGAGGAAGGGATCAGCCTCAGAGATGTCCGGCACGAGTTAAAGGAGGTGGAAGATAAGTTCCGAAAGGCGATGATACAGAATGCCCAGTTGGACAACGAGAAGGCATCCCTCACCTACCAGGTGGAACTCCTTAAGGACAGGCTGGAAGATCTGGAGGAGTCCCACTCGCAGTTGCAGCGTGAGCACCGCGACAAGTGTCGAGAACACGATCAGCTCAAGAGAGCGTCCGCCAAGTTGAAGGAAGACATGGAGTGGTACAAGGCGCAGTTGGAAGAGAGGGATAGACTCATTCAGGAGAAGGGCCTTATAATCGTGGGTGACGACCAGCTTTCCAGCGAGGACGAAAGTGTGGGTGACGACTCGCCCAAGAAACCTCCCAAGAGGGCTCTGGTCTCCATCGAGTCGGCGGAGATGTTGGAAACTGCAGGAGAGGGCTCTTTAGACGTACGGCTGAGGAGGTTTGCGGAGGAGCGCAACGAACTGCTGGACCAAGTGAGGCACCTCAAACTTGAATTGGAAGAGGAGCGCAGCAGACACAAGTCCGACGCCAAGAGGATACCCGGGGCCAGCCTCAACGGCCCTGACACAGATTTTGAGGACATTCAGAGGGAGGCCAACAAGCTTCTAGGGGACTACAAGTTCAAGCTACAGAAAGCGGAGCAGGATGTGTCTACACTGCAGGCCAATGTGGTGCGTCTTGAAAGCCAGGTGATCAGGTACAAGTCTGCTTCAGAGTCCTCGGAGAAGGGTGAGGATGAACTTAAGGTTGAGAAGAGGAAACTTCAAAGAGAGGTGCGAGAGTTGACGCAGCAACTGAGTCAGGCTGAGGCTGCTAAGGCTGCCTTGACTCATCAGTTCGACCAGCTTATGCTCGCCAAGAGATAA
Protein Sequence: MEDADECCFYDAVSEIPLSKPRMGNTAGAEGTKGGGRPGLSDEFPIVPVIDPRQDDSDDTSSSDPEIRSAPIDSDKESSTSLSDQSDLDERDDSGRPSMAVSRRDQRCTEASVGADSSGEEDAGVATFDDEGSLRVDRAVAKGVDLGVNLPDTFGESTTEDCEVQSVDDPVAEEKIVRNLRKDVLATPPKNEEPDGEVSDVSSSALGDVPRSSPDGDKSSVSTEEDNLVSKNNGKTVEDTLLAAESGCDGADSQDSRKCLDEAPSEESANQVGSSVIDNSASGSGSSKKVDIGNDVTDISKEEERLISKVEDKKEEDIDKIPKNKDIVGELKDVKEEDGKQNDIVGELGDLKVEDGKKNEIVGELGDLKGEDRKKNDLVGELEDIKEEEGKKNDIVGELGAEKGEDEKKNDIVGELGGVKGEDGKKKDVVGELGSDNDDNRGVKRVENVPGNLFWEESKKGKEDTADINGMKEDAIDKAVDINDGDYTTEDSDGYDLDDDEDINNKYISKGNVVDETENEEDADYLNNFLGKSNDQAEARLAARRQARAEAREIRMRELERQQKEIEENTNKSYDSFTAEPGNRTPRVATSVNRSSSLLSGGGNNSYHSSRRSSEDSLEEGISLRDVRHELKEVEDKFRKAMIQNAQLDNEKASLTYQVELLKDRLEDLEESHSQLQREHRDKCREHDQLKRASAKLKEDMEWYKAQLEERDRLIQEKGLIIVGDDQLSSEDESVGDDSPKKPPKRALVSIESAEMLETAGEGSLDVRLRRFAEERNELLDQVRHLKLELEEERSRHKSDAKRIPGASLNGPDTDFEDIQREANKLLGDYKFKLQKAEQDVSTLQANVVRLESQVIRYKSASESSEKGEDELKVEKRKLQREVRELTQQLSQAEAAKAALTHQFDQLMLAKR*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01444786;
90% Identity: -
80% Identity: -