Basic Information

Insect: Timema cristinae
Gene Symbol: -
Assembly: GCA_002928295.1
Location: CM009474.1:11975065-12010901[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00063 0.092 14.7 4.1 1 23 239 261 239 261 0.97

2 11 1.9e-05 0.0028 19.4 1.5 1 23 267 289 267 289 0.98

3 11 0.00021 0.03 16.2 2.4 1 23 295 318 295 318 0.96

4 11 0.077 11 8.1 3.4 1 21 324 344 324 346 0.95

5 11 0.00019 0.028 16.3 1.9 1 23 352 374 352 374 0.99

6 11 2.2e-05 0.0032 19.3 1.2 1 23 380 402 380 402 0.98

7 11 0.00049 0.072 15.0 1.4 1 23 410 433 410 433 0.97

8 11 6.3e-05 0.0092 17.8 2.1 2 23 440 461 439 461 0.96

9 11 0.00015 0.021 16.7 0.6 1 23 467 489 467 489 0.98

10 11 2e-06 0.00029 22.5 2.4 1 23 495 518 495 518 0.97

11 11 3.1e-08 4.5e-06 28.2 0.8 1 23 532 554 532 554 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00063	0.092	14.7	4.1	1	23	239	261	239	261	0.97
2	11	1.9e-05	0.0028	19.4	1.5	1	23	267	289	267	289	0.98
3	11	0.00021	0.03	16.2	2.4	1	23	295	318	295	318	0.96
4	11	0.077	11	8.1	3.4	1	21	324	344	324	346	0.95
5	11	0.00019	0.028	16.3	1.9	1	23	352	374	352	374	0.99
6	11	2.2e-05	0.0032	19.3	1.2	1	23	380	402	380	402	0.98
7	11	0.00049	0.072	15.0	1.4	1	23	410	433	410	433	0.97
8	11	6.3e-05	0.0092	17.8	2.1	2	23	440	461	439	461	0.96
9	11	0.00015	0.021	16.7	0.6	1	23	467	489	467	489	0.98
10	11	2e-06	0.00029	22.5	2.4	1	23	495	518	495	518	0.97
11	11	3.1e-08	4.5e-06	28.2	0.8	1	23	532	554	532	554	0.97

Sequence Information

Coding Sequence: ATGCAACAACCTGGGGTCGAGCTGGTCTCAAACACAGACATTGCGTTCCAAACCTCTAGCGGCGAGCGGTCTATCAAGATGGAGGGCCAGGAGGAGGCTGGCACCGAAACCATCACAGAGATCCAGAACTATTTAGAAACCTTCAACAAGGAGATCCAAAGTGGGGATCAGACGGTCCAGCACGTCACAGAAGTCCAGCAAGTTGTAACTTCAGACGATAACGCTGAGGAAGGAACTTATTTTGTAGATCAATCAGGTCACTACTACTACCAGGCAAATGCTGACTCTCAGCCCGTCATGACGGTTGTGTCAGGCATAGCGGACCCTGGTGGGGACGTGTCAGATGGGACAGGAGAGGCCACCTTCATGGCTGTTCAGCCACAGGACGCTCACGTGGAGGAGATCTCGGTGATGGACCAGGGCTCAGATGGCATGTCCAGCGGCACAGAGAGTAACCAAGTTATCCTCAACGCTGGTGATGCATACCAAGCGGTCACTATCGTACCGTCGGACTCTGGAGCCGGGGAGGTGAGCTACGTGCTCATTGTGCAACAGCCTGACGACAAGGATGACAAGGAGGATGACAACGACCTCACTGTGTATGACTTTGACGACGCAGAAGAAGGAGGCATCCAATTGGAATCCGGTGATGAAGACGACAAGACCAAGATCATCAAAATATTGCCAAAGAAATCTCAGACAGTGACCCAAGCCCACATGTGTAACTACTGCAACTACACGAGTCCGAAAAGGTACTTGTTGTCACGCCACATGAAGTCCCATTCGGAGGAGCGGCCCCACAAGTGCAGCGTGTGTGAGCGGGGGTTCAAGACACTCGCGTCGCTCCAGAACCATGTCAACACCCACACAGGCACTAAGCCCCACCGCTGCAAGTTTTGTGACAGCGCCTTCACTACATCTGGTGAGCTCGTTAGACATGTTCGGTACAAACACACTCACGAGAAGCCCCACAAATGCACGATTTGCGACTATGCCAGTGTGGAACTCAGCAAAATGAGGAACCATATGCGCTGCCATACGGGCGAACGCCCTTACCAGTGTCCACACTGCACGTACGCCAGCCCTGACACATTTAAGCTGAAACGTCACTTGCGCATCCATACGGGAGAGAAACCATATGAGTGTGACATCTGCCACGCTCGCTTCACGCAGTCCAACAGCCTCAAGGCACACAAACTTATCCACAGTGCAGGAGACAAGCCAGTGTTTCAATGTGAACTGTGTCCGACCACGTGTGGCCGCAAGACAGACCTTCGCATACATGTCCAGAAACTGCATACCTCGGACAGACCTCTCAAGTGCAAGCGCTGCGGGAAGTCTTTCCCCGACCGCTACTCCTACAAGATCCACAATAAGTCGCACGAGGGAGAGAAATGTTTCAAGTGCGATCTCTGTCCTTATGCTTCCATATCACAGCGACACCTCGAGTCTCACATGTTGATCCATACGGACCAGAAGCCCTACCAGTGTGACCAATGCGACCAGTCATTCCGACAAAAGCAACTCTTGCGGAGACACCAGAACCTGTACCACAACCCCAACTACGTGCCCCCACCTCCCAGAGAGAAGACCCATGAGTGCCCCGAGTGTGGTCGAGCGTTCAGGCACAAAGGTAACCTCATCCGGCACATGGCGGTGCACGACCCAGAGTCATCAGCGCAAGAGAAGGCGCTGGCACTGAAGCTCGGCCGACAAAAGAAGATACAGATCATTGACGGTCAGCACGTAGAAGTTATGGCAGGCGAGGATGATGACGAAGATGACGAGGACACTGATGGAGAGATGATGGCGGTAGAGGGTCAAGACGGACAGCAATATGTGGTGCTGGAGGTCATACAGCTTCAGGATGGGGAAGGAGGTGAGCAGGCCGTCGCCGTGGTGGCTGGGGATAGTTCACACTCCATGGGACACCTGCAGGGTCTGGACAGTGACGAAGAGGAAGAAGAGGGGCTGATGGCAGGACATCACATGGCGACAGACCctcttgatgatgatgatgatgatgatgaggtcATGCACACTCTCAGGGAAAGGAAACTGTCGAGAAAAGATGCGTTTGCCATCAGGAAGAAAATACAGACTGAGAAGGACATGCAGAACTGCTTCGGGTTTGACGACGATGGTGATGAGGTGGATGACGACGAAGCGGCAAAAACTACTATCCAATTTCTGGAGGCCATCAATCATTAA
Protein Sequence: MQQPGVELVSNTDIAFQTSSGERSIKMEGQEEAGTETITEIQNYLETFNKEIQSGDQTVQHVTEVQQVVTSDDNAEEGTYFVDQSGHYYYQANADSQPVMTVVSGIADPGGDVSDGTGEATFMAVQPQDAHVEEISVMDQGSDGMSSGTESNQVILNAGDAYQAVTIVPSDSGAGEVSYVLIVQQPDDKDDKEDDNDLTVYDFDDAEEGGIQLESGDEDDKTKIIKILPKKSQTVTQAHMCNYCNYTSPKRYLLSRHMKSHSEERPHKCSVCERGFKTLASLQNHVNTHTGTKPHRCKFCDSAFTTSGELVRHVRYKHTHEKPHKCTICDYASVELSKMRNHMRCHTGERPYQCPHCTYASPDTFKLKRHLRIHTGEKPYECDICHARFTQSNSLKAHKLIHSAGDKPVFQCELCPTTCGRKTDLRIHVQKLHTSDRPLKCKRCGKSFPDRYSYKIHNKSHEGEKCFKCDLCPYASISQRHLESHMLIHTDQKPYQCDQCDQSFRQKQLLRRHQNLYHNPNYVPPPPREKTHECPECGRAFRHKGNLIRHMAVHDPESSAQEKALALKLGRQKKIQIIDGQHVEVMAGEDDDEDDEDTDGEMMAVEGQDGQQYVVLEVIQLQDGEGGEQAVAVVAGDSSHSMGHLQGLDSDEEEEEGLMAGHHMATDPLDDDDDDDEVMHTLRERKLSRKDAFAIRKKIQTEKDMQNCFGFDDDGDEVDDDEAAKTTIQFLEAINH*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00995620;
90% Identity: iTF_01445040;
80% Identity: -