Basic Information

Insect: Timema cristinae
Gene Symbol: egg
Assembly: GCA_002928295.1
Location: CM009478.1:66118328-66121480[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 1.1e-11 7.9e-08 33.3 0.0 5 70 529 587 525 592 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	1.1e-11	7.9e-08	33.3	0.0	5	70	529	587	525	592	0.87

Sequence Information

Coding Sequence: ATGACTTTGGTAGAAGACAATATTCAAGACATAATTGAATCTACTATGAACAAATATGATGTTGATTTTCAATTGACTAAGGGAGACAAGATCTTAGAAAAAAGAGTTGCTAAACTAGAACAAAAAACTACCGAAGTTGATGAAAACTTTAATGATATCCAAAAATCTTTGGATGAGACAATGAGATTGCTATACAACGACTTTGCTCCTTTGATAAAAGAGTTACCACCTATAACAATTGTCGATGATGGAGTTCTTCCTATAAATGATTTAACTTCTCATCAAACAGCGACACTAATGAAGTATGGTTCTCCTAAATCTGCGAAGAAACATTTCTCCCCCGATGATGGCAGAAGACCTTTAGGGGTGGCAATGAAGAAAGTGACCCAAGTGCGGCAGTGTTTACTAGGAAATAATACTTCTGAAACAACTGTTTCAGATGCTGAGGGAAATATTGTGCAAGAGATAACTGTTCCAGATGTCGTGGCTCTAGAACAAGTAGATGTGACACACAAACCTTTGCCCCCGATAGGGCCAATACCTCGACCTACTCCTCAGCCAGGAGATATTGTTTATGTCATGAAACTGAGTTTTTATGGCTTGTGGTCTCGTGCTAAGATTATTGAAATTCTACCTAAAggaacaaaagaaaataatgtatcatctGAATATATTTCTGACATGTTTAAGGTCAAATTTGAATCAACATATCGTAAATCTAACCCTGTTAAAGTTGTCCAAGGGAAGCAGATGGCTTATCCAACACCTTGCCCTATGCGCTATCATGTTGGTACACGAGTAATAGCTATATTTAGTGAAGATGAACGAAGTAAGGAAAGTTTCTATGCAGGGGTCATTGCAGAACCCCCAAAGTCAATGAACAAATTCCGATATTTGGTGTTCTTCGATGATGGCTATGCCCAATATATTTCCCATGAGAAGATTCTCCTGGTCTGTGAAAGTTCTAAACAAGTATGGGAAGATATTCACCCAGATTCTCGAGACTTTGTGCGCAAATATCTTGAACAGTATCCAGAAAGACCAATGGTCAAGTTACAACAAGGTCAAATTGTTAAAACTGAGTGGAGTGGAAAATGGTGGATAGCGCGAGTGGTAGAAGTAGATGGATCAATGGTGAAGATGCATTTTGATGCAGACAATCGCTCTGAATGGATTTATAGAGGTTCAACTCGATTGGGTCCTTTGTTTGCTGAGCTAGCAAAGGGAGCCTATAGAAAAGAACAAGGCACTTTTCGTCATCGGGGTCTTGGCATAGCATCtctgaaaaagagaaacatgcCTTATGTAGAGTACACTCGAAACACTGATACTGAGGATACAAAAACTTCAGAGTCTGCGCCAGTACGTTCTGTGGCCAGAAAAAGTACGACAAGACTCCCGGACTACTATCAGGAAAACATTCCGAATCAAAGTGCCCTCAGTCAGGAAAGGTTATCGCAAGTCGGTAAAGTGGAAGAAGTGATTATTACAACAAAAGCCAAACCTAGAAGTTTTACTCGCCATCAATGCAGTCCTAGATGCTTGacagaaaatacttttgatttgaAGAATTTCCGAGGTGTCAACCCTTTGTGGATACCAATCATATGTGGCTGGCGTCGAGAGATAATTCATTTCCGTACTAAAAGAGTTATTGTTTATCGAACACCATGCGGTCGTCGTCTGCGGCGAATGGATGAGCTTCATAGGTACCTTAATGTCACCAGGGCACACCTGGGAGTGGATTTATTTGATTTCGACCACTGGGTTCATATTGCAGCAGAGTACACTTTAATTAACCCTggattcataaaaattaaagatctGTCGTATGGAATTGAAAATGTTCCAGTTCCTTGTGTTAATTCCATTGACCACACTGTGCCAGATTATGTTCCTTATTCTACTATGCGTCAACCAACAGCTGGTGTGTTCCTGAATACTGATCAAGAGTTCTTGACTGGATGTAATTGTGAGGATGATTGTAATGATAGGAGCAAATGTTCATGCTGGCAGCTCACAATTCAAGGGACAGGCTATGGGTCGAGTGGAGTAGTTGATACAACAATTGGCTACAATTACAAAAGGCTTCCAGAGCCAGTCATCACCGGTATTTATGAGTGTAACTCCCGTTGTAAGTGCAGTACTACTTGCATGAATCGTGTGGCACAACAGCCACTTCAACTCAGGctacaagtttttaaaactgaaaatcgAGGCTGGGGTATTCGCACGTTACATGACATTCCCCAAGGAACCTTCATTTGCATTTACGCTGGCCATTTGTTGACAGATCAAGAAGCCAACGAAGGTGGTAAAAATTATGGAGATGAATATCTTGCAGAGTTGAATTACATAGAAGCTGTCGAGAGGATGAAGGAAGGATATGAGAGCGATATTTTAGAGGATGACGATGGGGATGCAGAGGAAAAACAAGTGAATCAAGGTCACTCCAAACCAACAAAAGAATTAGAAACTGGGTCAGGCAAAGAGAGTTCTGGAGAAAGTGAGGAGGAAAATAGCCAGGATACAAGAGGCATGGATTCAGACGAAGAATTTAGACCAAATTGGGTAAAAAAGAAAGTGGCATCTAATGCCGGTAGCTCTATCAACACTCGACTCAGAGAAAGAACATCTCGTCATAGTTCCAATGACAGTGAGGGTAAAGagaagaaagttaaaaaagtgATCACCAAGGTGGAAAAGCAAGTTCTACAACATTCCACCAGTGAGGATGTTATAGTTTTGAGTGATGAAGAAGACACTGATATTGTCCGCAAACCATCAAAGTTTGCTGTCACAGAGGAACCAAAGAAAGGTGATAATACAGCATCAAGTTCCCCGTCTCTCTCCAAGTACAGATCTGTTAGAGAATTGTTTGGGCCAAAGGAATATTGCTACATCATGGATGCAAAGAATAGTGGTAACATAGGACGCTATCTGAATCATTCTTGCAGTCCAAATGTATTTGTCCAGAATGTGTTTGTAGACACGCATGACTTGCGGTTCCCCTGGGTTGCATTTTTTGCACTATCTTATATCAGCGCAGGTACAGAACTGACCTGGGATTACAGTTATGACATCGGCAGTGTGCCCGGCAAGGTGTTGCACTGCCATTGTGGTTCCACTGAATGTCGAGGGCGTCTGCTTTAG
Protein Sequence: MTLVEDNIQDIIESTMNKYDVDFQLTKGDKILEKRVAKLEQKTTEVDENFNDIQKSLDETMRLLYNDFAPLIKELPPITIVDDGVLPINDLTSHQTATLMKYGSPKSAKKHFSPDDGRRPLGVAMKKVTQVRQCLLGNNTSETTVSDAEGNIVQEITVPDVVALEQVDVTHKPLPPIGPIPRPTPQPGDIVYVMKLSFYGLWSRAKIIEILPKGTKENNVSSEYISDMFKVKFESTYRKSNPVKVVQGKQMAYPTPCPMRYHVGTRVIAIFSEDERSKESFYAGVIAEPPKSMNKFRYLVFFDDGYAQYISHEKILLVCESSKQVWEDIHPDSRDFVRKYLEQYPERPMVKLQQGQIVKTEWSGKWWIARVVEVDGSMVKMHFDADNRSEWIYRGSTRLGPLFAELAKGAYRKEQGTFRHRGLGIASLKKRNMPYVEYTRNTDTEDTKTSESAPVRSVARKSTTRLPDYYQENIPNQSALSQERLSQVGKVEEVIITTKAKPRSFTRHQCSPRCLTENTFDLKNFRGVNPLWIPIICGWRREIIHFRTKRVIVYRTPCGRRLRRMDELHRYLNVTRAHLGVDLFDFDHWVHIAAEYTLINPGFIKIKDLSYGIENVPVPCVNSIDHTVPDYVPYSTMRQPTAGVFLNTDQEFLTGCNCEDDCNDRSKCSCWQLTIQGTGYGSSGVVDTTIGYNYKRLPEPVITGIYECNSRCKCSTTCMNRVAQQPLQLRLQVFKTENRGWGIRTLHDIPQGTFICIYAGHLLTDQEANEGGKNYGDEYLAELNYIEAVERMKEGYESDILEDDDGDAEEKQVNQGHSKPTKELETGSGKESSGESEEENSQDTRGMDSDEEFRPNWVKKKVASNAGSSINTRLRERTSRHSSNDSEGKEKKVKKVITKVEKQVLQHSTSEDVIVLSDEEDTDIVRKPSKFAVTEEPKKGDNTASSSPSLSKYRSVRELFGPKEYCYIMDAKNSGNIGRYLNHSCSPNVFVQNVFVDTHDLRFPWVAFFALSYISAGTELTWDYSYDIGSVPGKVLHCHCGSTECRGRLL*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01447586;
90% Identity: iTF_01447586;
80% Identity: iTF_01445680;