Ttri042753.1
Basic Information
- Insect
- Therioaphis trifolii
- Gene Symbol
- egg
- Assembly
- GCA_027580255.1
- Location
- CM050410.1:28296932-28303191[-]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 2.1 2.4e+04 -3.7 0.1 10 23 71 84 69 87 0.80 2 2 3.1e-14 3.6e-10 40.6 0.0 3 71 564 626 562 631 0.90
Sequence Information
- Coding Sequence
- ATGGCATCAGAAGATCTTCCTCATGTAGACCTTACTGGAACTTTAACTGAGAGACAGTTCAAACAACTAAAATGTATAAACAGACTTTGTAATCATGGAGATGATCTAAGAGAAGCTATTGAACTAACATGTAATTACTATAATGTTGATTACAAACGAGGCAAAGAGGTTTGTACTCATTGTTTTGATAAGTGTATATCACATTATAAACGCCTTGAAAAAAAATGGGATCGCAGAGAATGTATTTTGAAAACCAATTTTCCAAATTTTGTATCACACCATGTTATAGAATCATCCTCATCATCAGAAGACGAAGAAGAATCAAGGCCTAGTATTTCTAAAAATGTATCTGATAATGAAATTACATCCCTTTTGAATAATGCGATTGATGCGTGGTTTCATGAAAACAAAAGTGTGATAAGCGAACACGTTGCAATGTGTGATGATCATATGAAAAATTTACAAGAAAGTTGTCTTGATAATATGAATGTATTAAATGAACTGTTTCGTACTGCAGAACGTAAACTGGATGGATTAATAGCTCAGCTGTATAAGCCATATAAACCAATAATTAAATATTTACCACCTGTAGATTTGACAGAGTCAAATTTAAAAAAAGACGTTGGGAATATGAGTGATAAGCATTATAAAAAGATTAAATTAGATGACAATAATGAAGAAGAAGATTTTAAAATTATATTAACTAGTGAAGAAGTTGAACCTTCACCTGCTGATTTACCTGTAATTGGACCTCAAGAGTATCCTCCTTTAAAAGAAGGAGATAGAATATATGCTATGCTGTTAAGTTCACCACAAAAATGGATTAAATGTAAAATAACGTCAGTGATTAATAAAGAGAATGTGCATGTTAAGTTTCGAAATATTGAAAAATTATTGACCACTAAAGAAATCGCGTATTCTACTCAGAATCTAGTGCAATTTAACGTCGGTTCCAGAGTGATTGCCAAGTGCAATAAAACTAATAATGGTTCAACTTCTACCTTTTTCTATGCTGGTGTAGTTGGCGAACCTCCCAAATTAATCAATAAATTCAGGTATTTGATTTTTTTCGATGATGGTAATGTTGAATATCGGCCTCATAAAGATATTCGTTTAATTGTACATACAACTTTCAAAGAAGTTTGGAATGATGTGTGCCCTGATTTGAAAGATTTTTTAAAAAATTATTTGGAAAATTATCCTGAACGTCAAATGGTAAAGTTGACCGAACAAGACTCTATACGAGCTCAATTTAAAAACCACTGGGTAGTAGCAAAAGTGATAAAAGTAGATGCATCTCTTGTCAAACTGTATTTTATGGAGTATAAAGTGTATGAATGGCTCTATCGTGGATCTCTAAGGTTATATAAAATGTATGAAAAACAGAACAAGTCTGAAAAAGGTATACGTTTAAGGCAATCAGGACTTGCTTATTTAAATAAACCAATTATTGAATACAGTAGCGTTGAAGAATCTGAATCTAAATGTGTAGCTCGTAAAAGTACTACAAAGTGTTCTACTTCATCTCTAAGTGACAAATCTCCACAAAGTAATTCAAATAACGATGATTTATATGAGACAGTTATATTAGAAGTACCTAAAACATGTCCTTACCCTAAACTGTTTACTTATCATGATTGTGATCCTTCATGTGTAGAATGGACGCTGTATGATTATAATAAAACTAAGCGAATGAATATGTTAGCTATACCATTGCATTTTGGTTTTAATAGGGCTTTGGTCATATTTAATAGTACTCAGAAAAATGTTTTTTATAAAACCCCGTGTGGTAAACGTATTCGAACCATGCCAGAAATGTTGAAGTACCTTATTGCTACTAAGAGCAAGATGACAATAGACCTATTTGATTTTAATAGCTGGGTTAGACCTCTGGCCGAGTTCAGAGTTTTAAAATCGCAACAATTTTTGAGTGATATATCTTGCGGCAAAGAATTTAAAGGGATAACATGTGTGAATAGTATTAATAATAAAATACCACCACCAATGTCATATATGACTTCTAGACAAGCAATGCCAGGTGTCAATATAAATGTTGAGAGTGAATTTTTATGTGGATGTGATTGCACAGATGATTGTCAAGACAAATCTAAATGTTCTTGTTGGAAGATGACTATTGATGGTCAAAAAATTTTACCTAATATTTACAAAGATCCGGATATTGGTTATAGTTATCGTAGATTACCTGAACGCGTTCTAACAGGTATTTACGAATGCAATAAAACATGTAAATGTTCTAGTTCGTGTTCAAATCGTGTTGTACAATTTCCTTTAAGACAGAAATTACAATTATTTTTAACTGAAAAGAAAGGTTGGGGTGTACGTTGTTTAAATGATATACCTCAGGGAAGTTTTATATGCATTTATGTTGGATACTTATTAACTGAAAACGATGCCAATGAATGTGGTATAAATTATGGTGACGAATATTTGGCCGAGTTAGATTATATTGAAGTTGTTGAAAAAATAAAAGAAGATTATGAAAGTGATGTACCAGCAAGTGAAAAAGAAACAAGCAATGAAATCAGTGTTGGAATTAGCCCTGGAGAGTCTGTATGCTTTGATGAAGATTTTCCTGAAACATCTCAAGCTAAAAGTGTAACTTCAGACATTTCACAACGGTTGCGTAAACGTAAAGAGCCTCAAAATGAGACTAAAGCTGATAAAGATGAAATTATTTCTAAATTAAATGATTCTATTTCTTCAAAACCGATGCGTGAATATTTTGGAGCAAATGAGAGTGTGTATATTATGGATGCAAAGACAAGTGGTAACATTGGGCGTTATTTAAATCATTCATGTAATCCAAACACATTTGTTCAAAATGTATTTGTGGATACACATGATCTGAGGTTTCCATGGGTATCATTTTTTGCACTACATTATATATCAGCTGGATCAGAACTTACCTGGGACTACAGTTATGATGTAGGGAGTGTTCCAGGAAAATATATGAAATGTCACTGTGGTTCAACAAGTTGTAGAGGAAGATTACTTTAA
- Protein Sequence
- MASEDLPHVDLTGTLTERQFKQLKCINRLCNHGDDLREAIELTCNYYNVDYKRGKEVCTHCFDKCISHYKRLEKKWDRRECILKTNFPNFVSHHVIESSSSSEDEEESRPSISKNVSDNEITSLLNNAIDAWFHENKSVISEHVAMCDDHMKNLQESCLDNMNVLNELFRTAERKLDGLIAQLYKPYKPIIKYLPPVDLTESNLKKDVGNMSDKHYKKIKLDDNNEEEDFKIILTSEEVEPSPADLPVIGPQEYPPLKEGDRIYAMLLSSPQKWIKCKITSVINKENVHVKFRNIEKLLTTKEIAYSTQNLVQFNVGSRVIAKCNKTNNGSTSTFFYAGVVGEPPKLINKFRYLIFFDDGNVEYRPHKDIRLIVHTTFKEVWNDVCPDLKDFLKNYLENYPERQMVKLTEQDSIRAQFKNHWVVAKVIKVDASLVKLYFMEYKVYEWLYRGSLRLYKMYEKQNKSEKGIRLRQSGLAYLNKPIIEYSSVEESESKCVARKSTTKCSTSSLSDKSPQSNSNNDDLYETVILEVPKTCPYPKLFTYHDCDPSCVEWTLYDYNKTKRMNMLAIPLHFGFNRALVIFNSTQKNVFYKTPCGKRIRTMPEMLKYLIATKSKMTIDLFDFNSWVRPLAEFRVLKSQQFLSDISCGKEFKGITCVNSINNKIPPPMSYMTSRQAMPGVNINVESEFLCGCDCTDDCQDKSKCSCWKMTIDGQKILPNIYKDPDIGYSYRRLPERVLTGIYECNKTCKCSSSCSNRVVQFPLRQKLQLFLTEKKGWGVRCLNDIPQGSFICIYVGYLLTENDANECGINYGDEYLAELDYIEVVEKIKEDYESDVPASEKETSNEISVGISPGESVCFDEDFPETSQAKSVTSDISQRLRKRKEPQNETKADKDEIISKLNDSISSKPMREYFGANESVYIMDAKTSGNIGRYLNHSCNPNTFVQNVFVDTHDLRFPWVSFFALHYISAGSELTWDYSYDVGSVPGKYMKCHCGSTSCRGRLL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01433119;
- 90% Identity
- iTF_01433119;
- 80% Identity
- -