Basic Information

Insect
Thereva unica
Gene Symbol
Aef1
Assembly
GCA_949987705.1
Location
OX465282.1:113250865-113251296[-]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.012 3e+02 3.6 0.2 22 46 17 41 12 43 0.87
2 4 4.6e-06 0.12 14.6 0.0 21 52 44 75 42 76 0.89
3 4 0.0017 42 6.4 0.0 21 51 72 102 70 103 0.87
4 4 9.1e-05 2.3 10.4 0.1 21 47 100 126 98 131 0.89

Sequence Information

Coding Sequence
ATGTCTCGTGCGATAAGTCGAACAATGACTGTAGCTAATGGCACTGTAGATAAGCCATTCCAATGTAATGTATGTGAAAGAAGATTTCGCCAATTAAGTACACTAACGAATCATGTTAAAATTCATACCGGTGAAAAGCCATATAAATGTTCAATATGCGATAAACATTTCCGACAGAGCAGTACACTTACAAATCACTTAAAAATACATACTGGTGAAAAACCATTCAATTGTACGTATTGTGGCAAACAGTTTCGTCAATTAAGTACATTGACGAATCATCTTAAAATACATACGGGCGAAAAGCCATTTGAATGTGTCGTTTGTAAAAAACAATTTCGTCAATCCAGCACACTTAATAATCACATAAAAATTCATGTAATGGATAAACTTTATATACCGTTTGAAATAAAGGCGGAAGAGGAAGGGTGA
Protein Sequence
MSRAISRTMTVANGTVDKPFQCNVCERRFRQLSTLTNHVKIHTGEKPYKCSICDKHFRQSSTLTNHLKIHTGEKPFNCTYCGKQFRQLSTLTNHLKIHTGEKPFECVVCKKQFRQSSTLNNHIKIHVMDKLYIPFEIKAEEEG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00203877;
90% Identity
iTF_01540912;