Basic Information

Gene Symbol
Aef1
Assembly
GCA_963855945.1
Location
OY979696.1:61039690-61040097[-]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.0057 90 5.1 0.1 22 52 9 39 4 40 0.86
2 4 6.1e-06 0.096 14.6 0.0 21 51 36 66 33 67 0.88
3 4 0.0019 30 6.6 0.0 21 51 64 94 61 95 0.88
4 4 0.0001 1.6 10.6 0.1 21 47 92 118 89 123 0.89

Sequence Information

Coding Sequence
ATGACTGTAGCTAATGGCACTGTAGATAAGCCATTCCAATGTAATGTATGTGAAAGAAGATTTCGCCAATTAAGTACACTAACGAATCATGTTAAAATTCATACCGGTGAAAAGCCATATAAATGTTCAATATGTGACAAACATTTCCGACAGAGCAGTACACTTACAAATCACTTAAAAATACATACTGGTGAGAAACCATTTAATTGTACGTATTGTGGCAAACAGTTTCGTCAGTTAAGTACATTGACGAATCATCTTAAAATACATACTGGCGAAAAGCCATTTGAATGTGTCGTttgtaaaaaacaatttcgtcAATCCAGCACACTTAATAATCACATAAAAATTCACGTAATGGACAAACTTTATATACCGTTTGAAATAAAAGCGGAAGAGGAAGGGTGA
Protein Sequence
MTVANGTVDKPFQCNVCERRFRQLSTLTNHVKIHTGEKPYKCSICDKHFRQSSTLTNHLKIHTGEKPFNCTYCGKQFRQLSTLTNHLKIHTGEKPFECVVCKKQFRQSSTLNNHIKIHVMDKLYIPFEIKAEEEG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00203877;
90% Identity
iTF_01540912;
80% Identity
iTF_01432684;