Tuni045908.1
Basic Information
- Insect
- Thereva unica
- Gene Symbol
- Mbd2
- Assembly
- GCA_949987705.1
- Location
- OX465283.1:74767428-74781812[-]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 2.6e-23 2.8e-19 70.5 0.0 3 73 5 70 3 74 0.91 2 2 0.00017 1.8 10.2 0.0 29 74 120 173 88 176 0.88
Sequence Information
- Coding Sequence
- ATGAACGCCGATAGAAGAAAAACTGATTGCAATGCTTTACCTAAAGGATGGCAGAGAGAAGAAGTCCTAAGGAAGAGTGGTTTATCAGCAGGAAAAGTGGATGTTTATTACTACAGTCCAACTGGCaagaaaatcgaaaataaaCCTCAACTGGCTCGCCAATTAGGTGACTCTTTAGATGTATCAACATTTGATTTTCAAACTGGAAAGTTATTGCCTAATGCTCAGCAAATATCTCTTCAGCGTACCGCAAGCTCATTAAAACGAAAATTACCAGCTGGAACAACAGCTTTATGTAGTCCTAGCAGTAGTGTGTCTTCAGCTGCTCTGCGACATCATCTTGAATTCAGTCGCGGTATACGTACAGATATTTCATTAGTACCACCAATACGGCAAACAGCATCAATTTTCAAACAACCAGTGACTGTACATCGAAATCATGAAGGAAAAGTACGTCATGATTTAAAACATGGCACACAAGAAAAACCAAAGCAACTTTTCTGGGAGAAACGCTTAGAGGGACTTCGTGCATTCGATTTAAAAGGGACAGAATTTGAACCAATCGATTTACCAAAAGGAATTAAGCCAGTAGGCCCAAATGTTAATGAGCAAACTGTATTACAGTCTGTTGCGACAGCTTTACATGTATCCAATCATCCAGTAACTGGCCAAACAGCAGCTAAAACTGTTTTATCAGTTAATTCTGGAATTTTTCTTAATCCCGATCAACCTTTAATGCAAGCAATCACTATAACAGAGGACGATATTCGAAGGCAAGAAGATCGTGTAAATTTAGCCAGACGAAGGCTTCAGGAAGCGTTGAAGGGTTAG
- Protein Sequence
- MNADRRKTDCNALPKGWQREEVLRKSGLSAGKVDVYYYSPTGKKIENKPQLARQLGDSLDVSTFDFQTGKLLPNAQQISLQRTASSLKRKLPAGTTALCSPSSSVSSAALRHHLEFSRGIRTDISLVPPIRQTASIFKQPVTVHRNHEGKVRHDLKHGTQEKPKQLFWEKRLEGLRAFDLKGTEFEPIDLPKGIKPVGPNVNEQTVLQSVATALHVSNHPVTGQTAAKTVLSVNSGIFLNPDQPLMQAITITEDDIRRQEDRVNLARRRLQEALKG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00877087;
- 90% Identity
- -
- 80% Identity
- -