Tatr022652.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Thecophora atra
Gene Symbol
tfap2e
Assembly
GCA_937641085.1
Location
CALMRH010000070.1:529433-541687[+]

Transcription Factor Domain

TF Family
AP-2
Domain
TF_AP-2 domain
PFAM
PF03299
TF Group
Basic Domians group
Description
Activator protein-2 (AP-2) transcription factors constitute a family of closely related and evolutionarily conserved proteins that bind to the DNA consensus sequence GCCNNNGGC and stimulate target gene transcription [PMID: 2010091, PMID: 1998122]. Four different isoforms of AP-2 have been identified in mammals, termed AP-2 alpha, beta, gamma and delta. Each family member shares a common structure, possessing a proline/glutamine-rich domain in the N-terminal region, which is responsible for transcriptional activation [PMID: 2010091], and a helix-span-helix domain in the C-terminal region, which mediates dimerisation and site-specific DNA binding [PMID: 199812]. http://www.ebi.ac.uk/interpro/entry/IPR013854
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 7.3e-82 1.1e-77 261.1 0.3 1 196 245 438 245 439 0.98

Sequence Information

Coding Sequence
ATGATTCTAAGCTCTCGGAAGCGGAACCGAAGCCCTGGCGCCATCAGATTGAAGGAGCGCCTTTCTAGTCATGGAAGTCTAGGATTGTCGAGCAGTAGTCCTGCCTACACCACTCACACCGGCGGTCATTCCGGGAGAGGCGGGCCAACTGGCCATGGTGGGCACAGCAGCTCTCATGGGTCGGCCGCAACCATGCACCACCAATCATTGCAGTCGGATTTCCAACCACCGTATTTTCCTCCACCGTTCCACCACTCCACACAGAGTCCGCCGCAACAACAGATGCCTTCTTATTTACAGAATCATGGAGCTCTTGAATACTTAGGAACCGATCCATATGGACAGCCGCTGTCGTCACTGCACCACGCCCCTCTGCATCATTACAACCAATTGGCTGGCCTTAGATCCACACAAGATCAGCTCGGCATTCATAGATCTCACAGAGAGGCAGAGCTCCAAGGACATGTGGCGCAGCTTTCGCACGGCTTTCCGTACACAGACAGACGGGCGGATTACGGAGGTGCTATATCAAGTGCCGCAGGTCACGGGAGCAGACTCACCCACGAACACGACTCCTTAGCTCTTCACCAAGCCTTGCAAAGTGCAGTCGACGATGGCCAGAATCCGGGGATGGACGACAACGTGGCTTTTATATCAGACTTACCTTTGATCAAAAGCATGAAAAGTGGGAAGGATGTCGGGAGCGTAGGTTCGGGATCGCCGAGTGAGGTTTTCTGTGCTGTACCTGGCCGGCTCAGTCTGCTTTCGAGTACTTCGAAGTACAAAGTAACGATTGCGGAAGTGCAGCGTCGGTTATCACCGCCGGAATGCTTAAATGCGTCTCTGCTGGGAGGCGTACTACGAAGAGCTAAGAGCAAAAATGGTGGAAGACTACTGCGCGAGAAATTGGAGAAAATAGGATTAAATTTACCAGCGGGTCGGCGGAAGGCGGCGAATGTCACGCTCCTAACTTCACTGGTTGAAGGCGAAGCAACTCACTTAGCAAAAGACTTTCATTTCGTGTGCGAAACGGAGTTTCCTGCACGGCAACTGGCCGAATATATTGTGAGGCATCAAACGGAACCGCAAGAATCATATCGGAGAAAAGAGCTGCTTTTGCATTCCCAACAGATTACAAAGGAACTCATGCAAGTTCTGAGCCAGGACCGAACAACTCAGTACGGCACCAGATCACAGCATTTGCTGGAACCGTCGATGCAGCGCCACCTGACGCACTTTTCCCTAATAACACATGGATTCGGTTCCCCTGCAATCATGGCAGTACTCCACGCCTTCCAGACCTTTCTAAATGAATCGTTGAACTACTTGGATAAATTGTATCCGTCGAATGGAGGAGGAATGATTTCGTCGTCCTTGGATAAAAATAAACTCGACAATGATAAAAAATGA
Protein Sequence
MILSSRKRNRSPGAIRLKERLSSHGSLGLSSSSPAYTTHTGGHSGRGGPTGHGGHSSSHGSAATMHHQSLQSDFQPPYFPPPFHHSTQSPPQQQMPSYLQNHGALEYLGTDPYGQPLSSLHHAPLHHYNQLAGLRSTQDQLGIHRSHREAELQGHVAQLSHGFPYTDRRADYGGAISSAAGHGSRLTHEHDSLALHQALQSAVDDGQNPGMDDNVAFISDLPLIKSMKSGKDVGSVGSGSPSEVFCAVPGRLSLLSSTSKYKVTIAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRLLREKLEKIGLNLPAGRRKAANVTLLTSLVEGEATHLAKDFHFVCETEFPARQLAEYIVRHQTEPQESYRRKELLLHSQQITKELMQVLSQDRTTQYGTRSQHLLEPSMQRHLTHFSLITHGFGSPAIMAVLHAFQTFLNESLNYLDKLYPSNGGGMISSSLDKNKLDNDKK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00580357;
90% Identity
iTF_00424330; iTF_00454219; iTF_00426801; iTF_00627905; iTF_00160355; iTF_00362935; iTF_01223895; iTF_01116133; iTF_01044422; iTF_00118375; iTF_01396168; iTF_00983910; iTF_00893545; iTF_00974316; iTF_01317905; iTF_00426034; iTF_00663731; iTF_01356531; iTF_00334653; iTF_00693469; iTF_00665310; iTF_00309898; iTF_01541841; iTF_00876714; iTF_01049322; iTF_00642893; iTF_00187728; iTF_01195697; iTF_01256088; iTF_00643769; iTF_00233598; iTF_01518571; iTF_00234487; iTF_01297054; iTF_00971866; iTF_00816225; iTF_00804866; iTF_01485858; iTF_01521571; iTF_00904452; iTF_01300485; iTF_00191752; iTF_01563368; iTF_01299689; iTF_00510218; iTF_00670634; iTF_01404490; iTF_00506539; iTF_00797419; iTF_01562443; iTF_01395532; iTF_01551404; iTF_00672557; iTF_00557582; iTF_00587086; iTF_01559438; iTF_01520655; iTF_00257489; iTF_00724436; iTF_00803285; iTF_01541109; iTF_00575254; iTF_00389303; iTF_00608119; iTF_00747159; iTF_01557240; iTF_00240345; iTF_00518841; iTF_00671898; iTF_00966845; iTF_00976125; iTF_00583359; iTF_00624415; iTF_00671296; iTF_00804064; iTF_01211584; iTF_01554368; iTF_00310689; iTF_00315617; iTF_00313124; iTF_00314826; iTF_00312267; iTF_00311482; iTF_00313946; iTF_01054914; iTF_00303491; iTF_00600739; iTF_00535747; iTF_00580357; iTF_00580359; iTF_00611079; iTF_01549959; iTF_01319434; iTF_00514575; iTF_00486992; iTF_00517393; iTF_00474196; iTF_01558712; iTF_00603033; iTF_00473467; iTF_00471293; iTF_00899207; iTF_00259457; iTF_01114689; iTF_01315170; iTF_01019107; iTF_01165219; iTF_00655012; iTF_01260678; iTF_00045064; iTF_00921130; iTF_00679148; iTF_00817100; iTF_01373740; iTF_01176623; iTF_01314351; iTF_00199540; iTF_01427157; iTF_01312726; iTF_00921783; iTF_00997402; iTF_01258906; iTF_00741531; iTF_01374651; iTF_01313437; iTF_01376317; iTF_00349854; iTF_00384254; iTF_00749374; iTF_01113886; iTF_00900223; iTF_01109023; iTF_01173855; iTF_01201280; iTF_00192488; iTF_00812393; iTF_00193235; iTF_00191051; iTF_01002455; iTF_00748666; iTF_00746395; iTF_01045150;
80% Identity
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