Dbif009499.1
Basic Information
- Insect
- Drosophila bifasciata
- Gene Symbol
- tfap2e
- Assembly
- GCA_009664405.1
- Location
- CM019043.1:28071532-28076033[-]
Transcription Factor Domain
- TF Family
- AP-2
- Domain
- TF_AP-2 domain
- PFAM
- PF03299
- TF Group
- Basic Domians group
- Description
- Activator protein-2 (AP-2) transcription factors constitute a family of closely related and evolutionarily conserved proteins that bind to the DNA consensus sequence GCCNNNGGC and stimulate target gene transcription [PMID: 2010091, PMID: 1998122]. Four different isoforms of AP-2 have been identified in mammals, termed AP-2 alpha, beta, gamma and delta. Each family member shares a common structure, possessing a proline/glutamine-rich domain in the N-terminal region, which is responsible for transcriptional activation [PMID: 2010091], and a helix-span-helix domain in the C-terminal region, which mediates dimerisation and site-specific DNA binding [PMID: 199812]. http://www.ebi.ac.uk/interpro/entry/IPR013854
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 0.56 8.3e+03 -3.9 0.0 170 181 152 163 144 171 0.74 2 2 2e-82 2.9e-78 262.0 0.2 1 196 242 435 242 436 0.99
Sequence Information
- Coding Sequence
- ATGACTTTAGCGTATGTGGATATGCCAGCGGTTCATGTTCAGGAGCGCCTTAGTGGACATGGGAGTCTAGGACTGTCCAGCAGCAGTGCGGCTTACACGACCCATTCCGGCGGACACACGGGTAGAAGCGGTCCGGCCACGGGGCACAGTGGACACAGTGGTACTCATGGGTCAGCAGCTACCATGCATCATCAATCACTTCAGTCTGATTTTCAGCCTCCGTACTTTCCGCCTCCGTTCCACCATTCGACGCAAAGCCCTCCTCAGCAACAGATATCTGAGTACTTGCAGAATCACGGTGCCCTCGAGTACCTGGGCACGGATCCGTATGGCCAGCCCTTGTCATCGTTACATCATGCCCCCCTCCATCACTACAATCAGTTGGCGGGCCTGAGGTCGACGCAAGATCAGCTTGGGATTCATAGAACCCACCGAGAGGCGGAGCTGCAAGGACATGTTTCCCAGCTGGCTCATGGATTTCCGTACACAGACAGGAGAAGCGACTACAGTAGTGCAATATCGGCAGGAGCAGCGCATGGAACCCGACTCGGGCACGAACATGAGTCCCTGGCCCTGCATCAAGCGCTGCAAAATGCTGTCGATGATGTCCAAGCACCTGCCATAGATGACAACGTAGCCTTCATGTCCGACCTTCCCCTTATAAAAAGCATGAAAAGCGGTAAGGATGCAGGGAACATTGGCTCTGGTTCCCCCAGTGAGGTATTCTGTGCAGTTCCTGGTCGCCTTAGCCTCCTATCGAGCACTTCGAAATATAAGGTCACCATTGCGGAAGTGCAACGAAGACTGTCGCCACCCGAGTGTTTGAACGCCTCCTTGCTGGGCGGAGTTCTAAGAAGGGCCAAGAGTAAGAACGGCGGCCGTTTGCTAAGGGAGAAGCTCGAGAAGATCGGCTTGAATCTACCAGCGGGAAGGCGAAAAGCGGCGAATGTGACGTTGCTAACATCTTTGGTGGAGGGCGAGGCAACACACTTGGCCAAAGATTTTCACTTTGTTTGCGAGACAGAATTCCCGGCCAGACAGCTGGCGGAGTATATTGTGCGTCATCAAACCGAGCCCAATGATTCATATCGACGAAAAGAGCTCATCCTTCACTCCCAGCAGATTACAAAAGAGTTAATGCAGATCTTAAGCCAAGATCGAACGACTCACTTTGGAACAAGATCACAGCATTTGCTGGAGCCGTCGATGCAGCGTCACTTAACACACTTCTCCCTGATCACGCACGGGTTTGGTTCTCCTGCAATAATGGCCGTTCTCCATGCTTTCCAGACATTTTTGAATGAATCATTAAACTATTTAGAAAAGTTATACCCTTCGAATGGGGGTGGTATGGTGTCGTCATCATTGGACAAAAGTAAAATGGACAACGAAAAGAAATGA
- Protein Sequence
- MTLAYVDMPAVHVQERLSGHGSLGLSSSSAAYTTHSGGHTGRSGPATGHSGHSGTHGSAATMHHQSLQSDFQPPYFPPPFHHSTQSPPQQQISEYLQNHGALEYLGTDPYGQPLSSLHHAPLHHYNQLAGLRSTQDQLGIHRTHREAELQGHVSQLAHGFPYTDRRSDYSSAISAGAAHGTRLGHEHESLALHQALQNAVDDVQAPAIDDNVAFMSDLPLIKSMKSGKDAGNIGSGSPSEVFCAVPGRLSLLSSTSKYKVTIAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRLLREKLEKIGLNLPAGRRKAANVTLLTSLVEGEATHLAKDFHFVCETEFPARQLAEYIVRHQTEPNDSYRRKELILHSQQITKELMQILSQDRTTHFGTRSQHLLEPSMQRHLTHFSLITHGFGSPAIMAVLHAFQTFLNESLNYLEKLYPSNGGGMVSSSLDKSKMDNEKK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00915904;
- 90% Identity
- iTF_01426378;
- 80% Identity
- -