Basic Information

Insect: Thalpophila matura
Gene Symbol: Zfa
Assembly: GCA_948465475.1
Location: OX419180.1:14228002-14237191[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 23 0.0049 0.34 11.8 1.0 3 23 650 671 649 671 0.96

2 23 0.21 15 6.7 0.3 1 22 1054 1075 1054 1075 0.95

3 23 7.6 5.2e+02 1.8 0.4 1 22 1117 1138 1117 1140 0.82

4 23 0.017 1.1 10.1 4.8 2 22 1150 1170 1149 1170 0.93

5 23 2.2 1.5e+02 3.5 0.0 3 23 1179 1200 1177 1200 0.89

6 23 0.018 1.2 10.0 0.2 3 23 1221 1242 1219 1242 0.96

7 23 0.0038 0.26 12.2 3.5 1 23 1248 1271 1248 1271 0.95

8 23 0.13 8.8 7.4 0.0 1 23 1297 1320 1297 1320 0.90

9 23 0.019 1.3 10.0 3.4 1 23 1325 1347 1325 1347 0.97

10 23 0.0083 0.57 11.1 0.1 1 23 1353 1376 1353 1376 0.95

11 23 0.0024 0.16 12.8 1.3 1 23 1389 1411 1389 1411 0.97

12 23 0.00018 0.012 16.3 1.8 1 23 1457 1480 1457 1480 0.97

13 23 0.0049 0.33 11.8 1.7 1 23 1540 1563 1540 1563 0.96

14 23 0.0024 0.17 12.8 2.1 2 23 1590 1612 1589 1612 0.95

15 23 0.04 2.8 8.9 0.1 2 23 1618 1640 1617 1640 0.94

16 23 0.01 0.69 10.8 0.2 1 21 1684 1704 1684 1705 0.95

17 23 0.00043 0.029 15.1 1.0 1 23 1715 1737 1715 1737 0.93

18 23 0.00011 0.0078 17.0 0.3 2 23 1829 1851 1829 1851 0.93

19 23 4e-07 2.8e-05 24.7 1.4 3 23 1858 1878 1857 1878 0.98

20 23 0.079 5.4 8.0 0.4 1 23 1896 1918 1896 1919 0.95

21 23 0.19 13 6.8 0.0 1 23 1942 1964 1942 1964 0.97

22 23 0.028 1.9 9.4 0.6 1 23 1970 1993 1970 1993 0.95

23 23 0.00026 0.018 15.8 0.4 1 23 2001 2024 2001 2024 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	23	0.0049	0.34	11.8	1.0	3	23	650	671	649	671	0.96
2	23	0.21	15	6.7	0.3	1	22	1054	1075	1054	1075	0.95
3	23	7.6	5.2e+02	1.8	0.4	1	22	1117	1138	1117	1140	0.82
4	23	0.017	1.1	10.1	4.8	2	22	1150	1170	1149	1170	0.93
5	23	2.2	1.5e+02	3.5	0.0	3	23	1179	1200	1177	1200	0.89
6	23	0.018	1.2	10.0	0.2	3	23	1221	1242	1219	1242	0.96
7	23	0.0038	0.26	12.2	3.5	1	23	1248	1271	1248	1271	0.95
8	23	0.13	8.8	7.4	0.0	1	23	1297	1320	1297	1320	0.90
9	23	0.019	1.3	10.0	3.4	1	23	1325	1347	1325	1347	0.97
10	23	0.0083	0.57	11.1	0.1	1	23	1353	1376	1353	1376	0.95
11	23	0.0024	0.16	12.8	1.3	1	23	1389	1411	1389	1411	0.97
12	23	0.00018	0.012	16.3	1.8	1	23	1457	1480	1457	1480	0.97
13	23	0.0049	0.33	11.8	1.7	1	23	1540	1563	1540	1563	0.96
14	23	0.0024	0.17	12.8	2.1	2	23	1590	1612	1589	1612	0.95
15	23	0.04	2.8	8.9	0.1	2	23	1618	1640	1617	1640	0.94
16	23	0.01	0.69	10.8	0.2	1	21	1684	1704	1684	1705	0.95
17	23	0.00043	0.029	15.1	1.0	1	23	1715	1737	1715	1737	0.93
18	23	0.00011	0.0078	17.0	0.3	2	23	1829	1851	1829	1851	0.93
19	23	4e-07	2.8e-05	24.7	1.4	3	23	1858	1878	1857	1878	0.98
20	23	0.079	5.4	8.0	0.4	1	23	1896	1918	1896	1919	0.95
21	23	0.19	13	6.8	0.0	1	23	1942	1964	1942	1964	0.97
22	23	0.028	1.9	9.4	0.6	1	23	1970	1993	1970	1993	0.95
23	23	0.00026	0.018	15.8	0.4	1	23	2001	2024	2001	2024	0.96

Sequence Information

Coding Sequence: ATGAATGTGAACTATGATCGTGTTTGTAGACTGTGCTTGTCATCTCGAGGCGAATTACTGCCGATTTTTCCTACCACCAGTTCGGATGACTCGGAACCTCCCGTCCTCGCTTTGAAAATCAAGGATTGTGTATCCATACAGATAAACGAACATGACGACCTGCCGACTAATGTCTGCAGGAAATGCATGGACAATGTCAATAACTGGCATGTTTTTAAAAATGTATGTGAAAGGACACAAAACAAACTACTGTCTCTGAAAGATGGCAGCCAACTAGAAGAGGTGAAAATAAAAAGTGAACCACTATCTGATGAGGCTTATGACGATGGAGTGGTCATTGATGGCTCATATCCTGTCATTGAGAATGCTGGCTTGTCAAACAAGGTGCAACCTGAAGGTCCCCCGATCCTGGCTTCATTGGGGCTCACACCAAGAAGTGATAAGAAATGTGTGGATCCGAGAATGGATTGGCATCGGGTCCATGCAATTTTGGACATGGTTCAAGACAATGAGGTGATTGATTCTCTACAGACAAAAGAAGAATGTGATGTTTTGCAGCATTCTGACCATGACTCTGATACAGAGGCAGAACTCCAACCAGAAATTGATGATGATTTTGTTGATTGCAAAAGCGGTTACATATGCAAAAATAAAAAAGTTATATCCAAAATTCCGAAACTATCAACATCTGAAAACAACACCAGAATCAAAGAAGCTTTCAAACTCAGAAAACGTAAATCGGATGTTCGTAAACATTGTGCACGACCTAAAAATGCGTGGCAGTTGTTATTCACCGATGACCTACTGGAATTGATTGTTGCTTCTACTAATGAAAATATTCTGACAAATGGGAAAGGATTGACGGAGTCAACCAGCGTCAGCGAAATTAAAACGCTAATCGGTATTCTATATTTGCATGGCATAATACGGCCGACGCATCAGAAATGTAGTGACCTTTGGAACAGCGAATGTGGTGTTCCTTGCATTAGAAATGTCATGAAATACGAAAGGTTCAAATTCCTGCTTCAAAACATCAGCTTCGACAAAGAGGACGACGACAGCATCATACAGTTCGACATAATGAAGCGTATGCGCAAAGTATTCGAAATCTTTGCCATGAATTGCAGAACATCTCACGAGATCGAGAATATCGCAGTTATTGATGAGATCATCGTGCCTGTTTACGGACCTTGCCCATTTCGATATGATATTGATAAGAAACCGTTGAAGCGGGGCATAAAACTGGTATTGCTTGTTGATTCATCTACATTCTATATGAGCAATTTGGATGTCATAACTGATCCATATTTTGGCGCTGAAGAGATAACAAAAAAGTTGGTTCAGCATTTGGCTGGAACTGGTCGATCAATTGTTATGGACAGTTGGTTCACATCTTCCTCTTTGATAGATTGCCTGAGAAATGAGTACCAGTTGTTTTCTATCGCGGCCTTGCACCCGAACAGTGATATGATTCCACCACTATTTCTTTCTCAGTACAGGAAATGTCGAACATTTATGTCTGGATTTATTGACCATGAAGTGTCATTGACGTCATATGTCAATACTGAAGGGAAATCAGTTAATGTATTGACTAATGAGCCTAGATATTACAGAAAAGGTCATATAAATCACACTACAGTTGTATCAGTGTATAAGAAGAATCAGTCGGCTGTAGAAGTGGTTGACGTCCTCATGAATTACTACACCACCATGCAGCACACCAACGATTGGACATTGTCTTTATTCTTTACATTGCTGAACATTGCCTCTGTTAATGCTCAGGGAGCGGAGAGTGAAAATAATGAAGAAGACGAGGAAGAAATGAATGAGCCTGCACAAACATTCCCCAAAATGCCCCATATGCCGGAGGTATCCATCACAGTCATGAGGCCTACGGGTGAAACCCTGCACGCTCGCCAAGGTATTCACCAACTCGCCTCCAAAGACTGCCTGGTCTGCGGCCGCTCCTACAGGTACTCTCACAACGCTCGCAGACATGAACTTACCGCTCACAGCTTCGACAGATATACAAACAAAATTACCCCTAAGAAAACCCTCTCTCATCTACAACCTAAACTCAGACCAAACCCATTCAACCCCAAAGCACGGATGATGCCGAATCCTATTAGTCATAAGATGCAGTTCTTGAACAAGCACATCCCAGCAAAAATAATGCCGGTAAACAAAGTTATAGCGCCACAAAAGCCCATTCCAATAAAGTCGTCAAAGAACCTACAAAATAATTTACCTTATCCTCTACGCATTAAAGCTCTCAAAGATTTACAAATAAAGAAAAAGGAGCCTCAGATTCTAAAGACTTTGTTGACCGCTAAACCTGAAGTTCTGGTATCAGAACCTGAAATATTAAATTCTGGTCCTGAAAGTCCAGAAACATTGATATCTGAGCCTGAAATTGCGTCTTTTCAAGTCGAGGCTATTCTTACGGAACCCGATGCTGATGCATACGACCCACAGCCAACCGAAGAAGAAGAACCTGACGAAGACACGCAGAACAATCAAAGTCAAAACTATGACACAGTTGATATGGACTCTGAAAATGAAATTGAGATTGCTCGTCAGCAAGGTATTGAACAAGACGGTGACGACAATGCTGATGGAGAAGAGAATTGTGATGACGATAATAATATGGAAGGCGCTCAGAGCGATAATGAAAAAGACGGTAACGACGATACAGTAGAAAGTCAAGAAAATATGGATGAAGATGATAGTGTTGATATTAAAGCTGAAGATGAAATGAAGGACGATGTCCATGAGGAGCAAGAACACGAAGAAGTTGAGGTAAATCATAATGATAATGAGGAAGAAGACGAAGATGACCTTCCAATATCATTGGCGCCAGTCGTCGAAATAAGTGAGGGTTTGCAAACAAACTCAAACAACGAAGTTCAGGAGGAAGAAGAGGAACTTGATGAAACCGCCGATCCCAATGAAACTGAAACCATGGACGACGAAGAGCAGGTTAAAGAACTCGACCCTGACAAAACATATGTTACAAAAACCCAAAGAGACTTCATCCAGAAATATCGCGACGTCATTCAGCAAATCAACACAAAACGTTGTTTATGTTGTGACAGAGAACATCCGCGTAGAAAAGCTGTTATACAACACTTGCAGAAAAACGGACACAAAGTACCAAAACACACTTGTTACAATTGTGTCATCACATTCGGCCATATTGGCGCCCTACTCAGCCATATGAGGTCGAATTCTTGCACTAATTTGTGGAAGATTATTTACAACGAAAACGGCATTACTGATGACTTAGTTCTCGAAGATGAGCCGAAAGAAGTCAAGGTTCAGTACAAAGATATTTTCAACGCCAGATCTTATGCATGCAAGCTCTGCCCAGCTAAGTTCCAACTGAAACAGTTTATTATGAAACATGTTTTGGATACACATGAGGATGGACAGTCGAAGGTGCCACTCTGTTGTGTCCACTGCCGTTCTAGGTTTAAAGACAAAAGTTTGCTTAAGAAACACATTCGTAAAGGTGAATGTACAGTTTATATTGCTTGCGATTTGTGTTCAGAAAAGTTCGGGAACATGCAGGATTTCAACGACCACGCTCTAGCTATCCACGCTGGCAGTTTCGATCAATCGGATAATCAGAGCAAATGTGTTGACGGCCGACCAACTGACTGTCCGTTGTGCGGAAAGAAAAACAGCAGCTATCCTAATTTAGTGAAACATTTGAAGATTATACATAGCGAGGAGAAACCTCACTACTGCCAACATTGCGACTCTAAATTCGAACAAGCTACTGATCTGAACAAACACATTTACATGGAGCATTCTGACAGAACGTTGGGCATGTCGACCGCTGAACCGGATATGTCCATAGTGAAGGAAGAAGCGGAGGAGTACCACTACTCGTGTACGGAATGTAATGCTATATTCGAAACTGTCGACGCTTGGACTGATCACCAAGTCGCCGAACATAACCAAGTGGCCCACCACTGCGACCAGTGTGAGAAGAAATTCCTTCGTCCGTCAGAACTTGCAGAGCATAAGAACACTCACTTGAGGGTTAAGTTCTACCCTTGCAGTGTATGCCCGAACTCTTACAGCACCCCACAGAAACTGTCTGAGCATGTACAGCAGGCACACGCCGGAGTTGGCCCAGTCGTTCCAACCGAGTCAGAATTCTTCTGCGACATCTGTATTAGATCGTTTAAAAGTCGCCAAGCTTACTCAAATCATATGCGTATTCATGCTAAAATACCAACTACTAACAGGAAACCAGGGGGATTTGCACCACAAATTATCGGAAAGCCTATCAAACAGTATCCCGTGGTTCAACCTGGTTTTGTATCATTTAAACCTAATTATAATATCCCTAATGCTCCATACTCTTGTGACATTTGTGGCAAAGGATTCATGCACAAGAAGAATATATGGAAACACAAGAAAGTGTTGCATGCAGACATTTTAGTAGATAGACATGACAGTGAAGAGAATACTATGCAAGCTTCCACAGAAGAGGAAGAATTTAACCCCGATGAGAACGGTGCCGTCCTCTCAACGCCACAATTTAATAGTTTTAACTTTTCGAACTTCCCAAACAATGCACAACAAACACCACCAGACACGATGCCTTACTCGTGTGAACTATGCTTCAAACGGTTCCCACTTAGGACCAGTTTGTGGAAACACAAACGTGCTAAACACGGAATTGTAAACCCTAGTACTAGTGGTACCAACGATACATCCACGCCATCGGCTAGCGGTGAAAGCAGCAGTAGATCTAGTTGCACTATATGTAGAATCACGTTTTCGGATAAAAAATCTTATTATCGCCACCGAAAGAACGTCCACAAATCGACCGTTCAAATGTGTAAAATATGTGGCAAACCTTTAAGTTCAACATTGGAATTATACGAGCACTTGAAGGCCGCTCACGCAAGGGAATTACTGGGTTATAACGCTAACCAAGGTTCCAGTAAATCCCAAGATGTGGCTCAAGAGACTGAACCCGATTATGAAAATGATCAAGAGTCTGTTGACCCCAGCGTCGATTACCAAGCGCGCTACCCGTGCGACACTTGCGGCAAACAATTTGTAGGTTTGCTTGCGTTGCAGAACCACCAGTGCATCAATCAGATAGCAGCACAACCACAGACGTTTGACTGCGAGATTTGTCACAAGAGTTACACTTCAATATCTGCGCTAAAAAGCCACCGCGGGTGGCATTTACGTTCGCCCGATGGAAAAGCAGCCGCAAACAACTCTGGGCTTTGGATGCCTCAGCACAAAGTTACTAGCAAGATAAGCAAACATGAAGTCGTCGACCCGTCACAACTTGCTAAGGTCACACATACCCCCGCTCCCCCTCCCGTCACCGCTACAGTAGCGAAACGAAGACTACCGCCAGAGGTCGAGGTCACAGTCGTAAATCCAAATAAAAAATTGCGCTCAGACGATTCGGTTGACTTGGATCAAAATTCTGGTGCAATCGAGGATAGGTACTGTACGATTTGCGACAAAGAATTTACGAAACGAGCGGCGTATCAGCGCCACATGGACGAAGTGCACCAACCGAACTCCGTGTTTTGCCCGGTCTGCGATAAGAGCTTCACAAGGAAGTCCACATTGCTCATTCACATGAAGAAACACTACGAGAGTGGTGAGGGCAGTTCCTCTGCTACAGGTCAAGGGGACGATGAATTCTCTTGTGATTTGTGTGGCGCTCAGTATGACAGTGATCAAGCGTTGAGGGCGCACCGAGTGAGGCACCACGCAGAAGAAGAAGAGTCAGCAGAAGAAAGTGACGACGGAAATGTTCCTATAGCTCCTCCCGGTGAATTCACGTGTGCGCAATGTGGCGATGGCGTCGCTACACCCAGAGACCTCATCGCGCATCGCACAATGCACGCCACTCCCACCAAATTCTTCTGTAACATATGCAAAGTTTACTTCGCTCGCGCGCTCGATCTCTCCTCGCACACTCGGGCGCGACACGCTGACAACGAAAAGGTATTCTTCCCGTGTGCCATGTGCGACAGATTTTACATGAACAAGAAGAGTTTGCAGCGGCACATCGAGATGGCACACTGA
Protein Sequence: MNVNYDRVCRLCLSSRGELLPIFPTTSSDDSEPPVLALKIKDCVSIQINEHDDLPTNVCRKCMDNVNNWHVFKNVCERTQNKLLSLKDGSQLEEVKIKSEPLSDEAYDDGVVIDGSYPVIENAGLSNKVQPEGPPILASLGLTPRSDKKCVDPRMDWHRVHAILDMVQDNEVIDSLQTKEECDVLQHSDHDSDTEAELQPEIDDDFVDCKSGYICKNKKVISKIPKLSTSENNTRIKEAFKLRKRKSDVRKHCARPKNAWQLLFTDDLLELIVASTNENILTNGKGLTESTSVSEIKTLIGILYLHGIIRPTHQKCSDLWNSECGVPCIRNVMKYERFKFLLQNISFDKEDDDSIIQFDIMKRMRKVFEIFAMNCRTSHEIENIAVIDEIIVPVYGPCPFRYDIDKKPLKRGIKLVLLVDSSTFYMSNLDVITDPYFGAEEITKKLVQHLAGTGRSIVMDSWFTSSSLIDCLRNEYQLFSIAALHPNSDMIPPLFLSQYRKCRTFMSGFIDHEVSLTSYVNTEGKSVNVLTNEPRYYRKGHINHTTVVSVYKKNQSAVEVVDVLMNYYTTMQHTNDWTLSLFFTLLNIASVNAQGAESENNEEDEEEMNEPAQTFPKMPHMPEVSITVMRPTGETLHARQGIHQLASKDCLVCGRSYRYSHNARRHELTAHSFDRYTNKITPKKTLSHLQPKLRPNPFNPKARMMPNPISHKMQFLNKHIPAKIMPVNKVIAPQKPIPIKSSKNLQNNLPYPLRIKALKDLQIKKKEPQILKTLLTAKPEVLVSEPEILNSGPESPETLISEPEIASFQVEAILTEPDADAYDPQPTEEEEPDEDTQNNQSQNYDTVDMDSENEIEIARQQGIEQDGDDNADGEENCDDDNNMEGAQSDNEKDGNDDTVESQENMDEDDSVDIKAEDEMKDDVHEEQEHEEVEVNHNDNEEEDEDDLPISLAPVVEISEGLQTNSNNEVQEEEEELDETADPNETETMDDEEQVKELDPDKTYVTKTQRDFIQKYRDVIQQINTKRCLCCDREHPRRKAVIQHLQKNGHKVPKHTCYNCVITFGHIGALLSHMRSNSCTNLWKIIYNENGITDDLVLEDEPKEVKVQYKDIFNARSYACKLCPAKFQLKQFIMKHVLDTHEDGQSKVPLCCVHCRSRFKDKSLLKKHIRKGECTVYIACDLCSEKFGNMQDFNDHALAIHAGSFDQSDNQSKCVDGRPTDCPLCGKKNSSYPNLVKHLKIIHSEEKPHYCQHCDSKFEQATDLNKHIYMEHSDRTLGMSTAEPDMSIVKEEAEEYHYSCTECNAIFETVDAWTDHQVAEHNQVAHHCDQCEKKFLRPSELAEHKNTHLRVKFYPCSVCPNSYSTPQKLSEHVQQAHAGVGPVVPTESEFFCDICIRSFKSRQAYSNHMRIHAKIPTTNRKPGGFAPQIIGKPIKQYPVVQPGFVSFKPNYNIPNAPYSCDICGKGFMHKKNIWKHKKVLHADILVDRHDSEENTMQASTEEEEFNPDENGAVLSTPQFNSFNFSNFPNNAQQTPPDTMPYSCELCFKRFPLRTSLWKHKRAKHGIVNPSTSGTNDTSTPSASGESSSRSSCTICRITFSDKKSYYRHRKNVHKSTVQMCKICGKPLSSTLELYEHLKAAHARELLGYNANQGSSKSQDVAQETEPDYENDQESVDPSVDYQARYPCDTCGKQFVGLLALQNHQCINQIAAQPQTFDCEICHKSYTSISALKSHRGWHLRSPDGKAAANNSGLWMPQHKVTSKISKHEVVDPSQLAKVTHTPAPPPVTATVAKRRLPPEVEVTVVNPNKKLRSDDSVDLDQNSGAIEDRYCTICDKEFTKRAAYQRHMDEVHQPNSVFCPVCDKSFTRKSTLLIHMKKHYESGEGSSSATGQGDDEFSCDLCGAQYDSDQALRAHRVRHHAEEEESAEESDDGNVPIAPPGEFTCAQCGDGVATPRDLIAHRTMHATPTKFFCNICKVYFARALDLSSHTRARHADNEKVFFPCAMCDRFYMNKKSLQRHIEMAH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00017541;
90% Identity: iTF_00758469;
80% Identity: -