Timm008399.1
Basic Information
- Insect
- Tetramorium immigrans
- Gene Symbol
- TFAP2A
- Assembly
- GCA_011636585.1
- Location
- VBVO01003644.1:7158-8757[-]
Transcription Factor Domain
- TF Family
- AP-2
- Domain
- TF_AP-2 domain
- PFAM
- PF03299
- TF Group
- Basic Domians group
- Description
- Activator protein-2 (AP-2) transcription factors constitute a family of closely related and evolutionarily conserved proteins that bind to the DNA consensus sequence GCCNNNGGC and stimulate target gene transcription [PMID: 2010091, PMID: 1998122]. Four different isoforms of AP-2 have been identified in mammals, termed AP-2 alpha, beta, gamma and delta. Each family member shares a common structure, possessing a proline/glutamine-rich domain in the N-terminal region, which is responsible for transcriptional activation [PMID: 2010091], and a helix-span-helix domain in the C-terminal region, which mediates dimerisation and site-specific DNA binding [PMID: 199812]. http://www.ebi.ac.uk/interpro/entry/IPR013854
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 9.2e-37 1.3e-32 113.9 0.0 85 196 15 124 6 125 0.96
Sequence Information
- Coding Sequence
- ATGCCTATCATAAATTTGGAATACCTACGACGGATAACATTTcgAGAAGCCATTCACCTTGCCAGAGACTTCGGTTACGTTTGCGAAACCGAATTCCCCGCGAAGCAAGTCGCCGAGTACCTCAGTCGGCAGCATTGCGAACCACAAGACTCCTACAGGAGAAAAGAACTTCTTCATGCCACCAAACAAATCACCAAAGAGCTGATGGATCTTCTGAACCAGGACAGATCGCCGCTCTGCAATACGCGGCCACAACATATCCTCGATCCTAGTATACAGAGACATCTCACTCATTTCTCTCTCATATCACACGGATTCGGAAGTCCTGCGATCGTGGCCGCTTTAACGGCTATTCAGAAGTTCCTAAGCGAATCTTTGAATCATCTAGAGAAGATGTATCCCGGGAACGGCAGCGGCGTGACGAGCAGTCAACAGTCGAATCTCGACTCGAATAAAAGCAAGGATGGCGCGCTGATGAACGACATGAAGAAGTGA
- Protein Sequence
- MPIINLEYLRRITFREAIHLARDFGYVCETEFPAKQVAEYLSRQHCEPQDSYRRKELLHATKQITKELMDLLNQDRSPLCNTRPQHILDPSIQRHLTHFSLISHGFGSPAIVAALTAIQKFLSESLNHLEKMYPGNGSGVTSSQQSNLDSNKSKDGALMNDMKK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01228703;
- 90% Identity
- iTF_00384969; iTF_00867081; iTF_00765226; iTF_00128652; iTF_01519917; iTF_00877554; iTF_01411989; iTF_00719061; iTF_01412782; iTF_00718207; iTF_00939199; iTF_00125597; iTF_01270882; iTF_00280359; iTF_01354314; iTF_01422609; iTF_01453783; iTF_01418072; iTF_00182335; iTF_01421247; iTF_01266592; iTF_01424064; iTF_00279656; iTF_00024340; iTF_00127869; iTF_00129416; iTF_00127136;
- 80% Identity
- iTF_01422609;