Pcal008090.1
Basic Information
- Insect
- Pogonomyrmex californicus
- Gene Symbol
- TFAP2A
- Assembly
- GCA_017141365.1
- Location
- JAEVLP010004822.1:207856-209783[-]
Transcription Factor Domain
- TF Family
- AP-2
- Domain
- TF_AP-2 domain
- PFAM
- PF03299
- TF Group
- Basic Domians group
- Description
- Activator protein-2 (AP-2) transcription factors constitute a family of closely related and evolutionarily conserved proteins that bind to the DNA consensus sequence GCCNNNGGC and stimulate target gene transcription [PMID: 2010091, PMID: 1998122]. Four different isoforms of AP-2 have been identified in mammals, termed AP-2 alpha, beta, gamma and delta. Each family member shares a common structure, possessing a proline/glutamine-rich domain in the N-terminal region, which is responsible for transcriptional activation [PMID: 2010091], and a helix-span-helix domain in the C-terminal region, which mediates dimerisation and site-specific DNA binding [PMID: 199812]. http://www.ebi.ac.uk/interpro/entry/IPR013854
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 5.1e-38 8.7e-34 118.0 0.0 80 196 24 138 7 139 0.93
Sequence Information
- Coding Sequence
- ATGTATCTCTCTGTTTTCAGGCACGGAGGAAGGGAAAAAGCTAGCGTGGGCAGTATTGTGAAATTGGATAATTCGTTAGCTGCAGGAGAAGCCATTCACCTTGCCAGGGACTTCGGCTACGTTTGCGAAACCGAATTCCCCGCGAAGCAAGTCGCCGAGTACCTCAGTCGGCAGCATTGCGAACCGCAAGACTCCTACAGGAGGAAAGAACTTCTTCATGCCACCAAACAAATCACCAAAGAGCTGATGGATCTTCTGAACCAGGACAGATCGCCGCTCTGCAATACGCGGCCGCAACACATTCTCGATCCCAGTATACAGAGACATCTCACCCATTTTTCTCTCATATCACACGGATTCGGGAGTCCTGCGATTGTAGCCGCTTTGACGGCTATACAGAAGTTCCTAAGCGAGTCTTTGAATCATCTAGAGAAGATGTATCCCGGGAACGGCAGCGGGGTGACGAGCAGTCAACAGTCGAATCTCGACACGAACAAGAGCAAGGACGGCACGCTGATGAACGACATGAAGAAGTGA
- Protein Sequence
- MYLSVFRHGGREKASVGSIVKLDNSLAAGEAIHLARDFGYVCETEFPAKQVAEYLSRQHCEPQDSYRRKELLHATKQITKELMDLLNQDRSPLCNTRPQHILDPSIQRHLTHFSLISHGFGSPAIVAALTAIQKFLSESLNHLEKMYPGNGSGVTSSQQSNLDTNKSKDGTLMNDMKK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01421923; iTF_00109518; iTF_01213008; iTF_01422609; iTF_00765226; iTF_01354314; iTF_01519917; iTF_00024340; iTF_00961517; iTF_01267957; iTF_01418072; iTF_00125597; iTF_00127136; iTF_00129416; iTF_01266592; iTF_01270882; iTF_00881688; iTF_01424064;
- 90% Identity
- iTF_01244907; iTF_00961517;
- 80% Identity
- iTF_00961517;