Tflu022202.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Tetheella fluctuosa
Gene Symbol
-
Assembly
GCA_951216915.1
Location
OX578236.1:6244499-6263881[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 8.3e-16 4.1e-12 46.2 0.0 7 70 297 358 293 363 0.89

Sequence Information

Coding Sequence
ATGTCGGACGAAATGGCGGTGACTGATAACGCAGCGGGTGATGAAGCTAAAATAAACAGCGATGAGGCTGAAGTTGCGGGCGCTGGGGATGCAGCGGAGGTCTCTCCGGAGCTTCTGAGCGCATCTCCTATCCCGGAGACTGAAGATATACCCATGATAGATgatgATATGGGAGATGAACCTCCGGAACTAGAGAACATAGCAGAAGAAGCTCCAGGACCACTAGCAGATGTGATTAAGTCGGATTGCAAGCTTGAATTTGAAGTAGAACTCATTTCAGAAGCCCATTCTGACACTGAACCTACACCTGACTCAGAAATTAAAACTGACCCAGAAATTAAAACTGACTCAGAAATTAAAACTGACTCAGAAATTAAAACTGACTCAGAAATACAAGCTGACTCAGAAATTAAAACTGAAGAGGAAAAAACTGACATAGAAATTAAACCAGATTTAGAAGTGAAGTTAGAAGTTATAGAAGACCAATTGGACAGTGTAAAGGTGGAACAAGATGAAGACGATAAGCGAGGAGTGAAACGGAGGGCTTCAGCTGCATTTAGTGATGTCGGTGATGAAGACTTCAAAGGTTTCATCCTGTCTGGTGCAAATGATGTTGCTATGAAATATAGTCGAGTTTTGGaacGTCTGGAGGAGGAAGTGGTGATGACGGCCAAGGATATAGTCCCGTTGAGACAAGTGATGGGAACACCTAACGCACCTGTTAGGGCTTCAAAGAGACCGCGTAAAGATACTGATGGTTCAAGACCATCATCAGCTCTATCATCAAGGTCGGAGAGTGAAGGGTATACTGATACGGTGTTCGCGGGCGCGGGTGCGTCCCCGGCGCGCGGCGGTCGTCGCGCCACCACAGAGATGTCGTCGCCGCTGCTGCGCGTGCCGCTGGAGCGCGGCTGGCGGCGCGAGCTAGTGTACCGCGCCGCGCTCGACGCGCACTCGCGCCGCAACGCCGACATCTACTACTACACGCCTTATGGGAAGAAGCTGCGCTCCACGCGCGAggttGCCGAGCACCTCTCGGGGACCGGGCTGACGTTAGAAAACTTTTCCTTCTTCAAGGAACCACTAGGGGTTGATGACCCTGAGAAGGAGATCATTCGTGATGCAAAAATGATACGTCGCGTCGAGTCCCCGGTGTCGTCCCCGGCGCCGGCGGAGGGCAAGCGCACGCCCAAGCCCAAGCAGCCCAAGGGCGCCAGCCCCGAGCCCGCCgcgcccacgcccacgcccaaGTCGCCCCCTGCCAAGATTAAGGTGAAGTCAATGGGTTCCCGGCTCAGTGGCAGCGGAGCGCCGGCCTCCTCACCCGCAAACAAACAGAAGAAACCTCAGACACCGGCCACTGATAACAACAACACCGCTGCCTGGAAGAAGCCCagGGCCGTCCCGCCGGCCCCGCTCGCCCCGCACGTCCCGGCCGCCCCGCTCGTCCCGGCCGCCCCCGCAGCCccggccgcccccgccgcccccgtgctgccgccgccgcccctgCAGAGTCGCCCGCCGGCGATGACATCTCCCGATGTTAAGGTGGTGCAGGTGGTGCAGGTGGTGCAGCCGTGCTCGATGTCGTGCGGGCGCGGCGCGGTGCCGTCGCTGGCGTGCGCCGTGTGCCTGTGCCTGTACCACCCCGCCTGTGTAGCCACTCACACCGGGGCCCATGCGCAGCCCTTCCTGTGCCAGAATTGCCGCAAATCCCCATCTCCGCCCCCCTCCCCGCCGCCCCTGACTCAcaagtcgggcgtgaccgcaccgTCCGCCGCCGCGCCCGCAGCGGCACCGACGCCCGCAGCGGCTGCCGCGCCCGCACCGAGACGCGTGCccgtacctgtacctgtaccagtaccagtaccagtgCCGGCCAAAAGGCAAGATAAACGGGTGCTGTTGAGAATGAAGGTGGCAGGCGGTGGCGCGGACGGGTCCCGCGTGTGGGCTGTAGCGGCCCCCcgcgcgcccgccccgcccgccccgcctACCGCAGCGGCCGCACCCGCACCGGCCGCACCCGCAGCGGGCCCGGCAGCGGGCCGCCTGCACCAGCAGCGCGGGTCCCGCCCGCAGTCGCTGGCCGTGCTCAACGGACGCAGATTCATCATTGTGCCGAGAGCGCCGCCGCTGCATCAACTCGAAGAGAAGCGTCCAGTCCGCGGTCGTATGGCGAACGGCGCGACCGTGACCGCGACCGCGACCACGACGGCGGTCGCGTGCGGGTCgccgcggcggcgcgggcggccgcGCACCGACGACACCGACTACTTCACCGCCTTCTATAATAAAGCGCAGGAGAGGAACTATAATGTTGTTGTGCAGATATTCCAGTACCTAGGCATGCGCGAGCTGGCGCACTGCGCACGCACGTGCCGGCTGTGGCGCGCGCTGGCCGCCGAGCCCGCCCTCTGGAGGCACGTGCGCATGAAGAACTCACATGTGAGCGACTGGGGCGGGTTGTGCGCAGCGCTAAAGAAGCACGGCACGAAGCGGCTGGACCTGCGCAAGATGTTGTTGCCGCAAAACGACACCGTGTTCTGGGAACAATTCGCACAACACATATCCACTGTCGATACATTAGAGAGGATAGAGATGTGTCGTTGTCCCGCTCGCGCGGTGGAGGCGGTGTGCCGCGGCGTGGGCGGGCTGCGCGCGCTGTCGGCGCTGGCCATCCGCGACGCGCTGCTGGACCCCGCGCCGCTCGCGCGCCTGCCCAGGCTGGCCGAGCTGCGCCTCAAGAGCATGGCCGGCCTGTCGCTCACCAGCGACCTGCGCCACCTCGCCGCGCTCACCGGCCTGCAGCATCTCTCGCTCACCTCCATCAAgGAGCTAGGATGGTGCGCGTGCGACGTGATCGGGTCCCTCCCGCAGCTGGAGTCCCTCGAGCTGGGCGAGTGCACGTTCCGGGCGGAGTTCGCGACCGCCGTGTCGCGCCTGGTGCGACTGCGACGGCTGCGGCTCGAGAGAGGGACGGCGACGTGCGCCGCGCCCGCCATCCTGCGCGCGCTCGCTGCGTTGCCGCTCCTCACCAGGCTCGAacttgtcaatgttgatgttaaGCTCGGTTTCGACGACGCGCTCGCAGAATGCAAAAATATTCAGCGACTGCTCATCATACCGACGTACGTTTCACAATCGGCGACTACTAACAAACAGGTACTAAGCGGCGTCCTTCGGCTCAAAGACACCCTAACGCACCTAATGTGGGGGGTAACTATAGAGCTGCTGCGAGTCACAGAACTGTTCATAGACCAGTGCGAGCAGGGCGGCGATACGAAGAAGCGAGATATCGGCGAGTGCATCCCTGTGCTCAAGCCGGTCCCCGGGTGCAAGCTGCCCGAAGAAAATCCTCTTGTCGCTGGCCCGCCGCAGGTGGAAATTCTCCCGCTGCCGACTCTACAGCGCCTCCTGTCCGCTCAGTTGCCGAACACGAAGCTTAAGCTCCTGCGCATCCCGTTCCACGCCACCTGGCGGCAGTCGCTCGCGGACTTTCAGTAG
Protein Sequence
MSDEMAVTDNAAGDEAKINSDEAEVAGAGDAAEVSPELLSASPIPETEDIPMIDDDMGDEPPELENIAEEAPGPLADVIKSDCKLEFEVELISEAHSDTEPTPDSEIKTDPEIKTDSEIKTDSEIKTDSEIQADSEIKTEEEKTDIEIKPDLEVKLEVIEDQLDSVKVEQDEDDKRGVKRRASAAFSDVGDEDFKGFILSGANDVAMKYSRVLERLEEEVVMTAKDIVPLRQVMGTPNAPVRASKRPRKDTDGSRPSSALSSRSESEGYTDTVFAGAGASPARGGRRATTEMSSPLLRVPLERGWRRELVYRAALDAHSRRNADIYYYTPYGKKLRSTREVAEHLSGTGLTLENFSFFKEPLGVDDPEKEIIRDAKMIRRVESPVSSPAPAEGKRTPKPKQPKGASPEPAAPTPTPKSPPAKIKVKSMGSRLSGSGAPASSPANKQKKPQTPATDNNNTAAWKKPRAVPPAPLAPHVPAAPLVPAAPAAPAAPAAPVLPPPPLQSRPPAMTSPDVKVVQVVQVVQPCSMSCGRGAVPSLACAVCLCLYHPACVATHTGAHAQPFLCQNCRKSPSPPPSPPPLTHKSGVTAPSAAAPAAAPTPAAAAAPAPRRVPVPVPVPVPVPVPAKRQDKRVLLRMKVAGGGADGSRVWAVAAPRAPAPPAPPTAAAAPAPAAPAAGPAAGRLHQQRGSRPQSLAVLNGRRFIIVPRAPPLHQLEEKRPVRGRMANGATVTATATTTAVACGSPRRRGRPRTDDTDYFTAFYNKAQERNYNVVVQIFQYLGMRELAHCARTCRLWRALAAEPALWRHVRMKNSHVSDWGGLCAALKKHGTKRLDLRKMLLPQNDTVFWEQFAQHISTVDTLERIEMCRCPARAVEAVCRGVGGLRALSALAIRDALLDPAPLARLPRLAELRLKSMAGLSLTSDLRHLAALTGLQHLSLTSIKELGWCACDVIGSLPQLESLELGECTFRAEFATAVSRLVRLRRLRLERGTATCAAPAILRALAALPLLTRLELVNVDVKLGFDDALAECKNIQRLLIIPTYVSQSATTNKQVLSGVLRLKDTLTHLMWGVTIELLRVTELFIDQCEQGGDTKKRDIGECIPVLKPVPGCKLPEENPLVAGPPQVEILPLPTLQRLLSAQLPNTKLKLLRIPFHATWRQSLADFQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01083350;
90% Identity
-
80% Identity
-