Basic Information

Insect: Tenthredo scrophulariae
Gene Symbol: Hr39
Assembly: GCA_963978835.1
Location: OZ022230.1:15754666-15758956[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 4 3.1e+04 -5.8 15.7 66 163 204 296 99 345 0.59

2 5 4 3.1e+04 -8.0 9.7 70 160 297 372 252 409 0.37

3 5 4.9e-08 0.00039 20.8 0.0 1 21 498 518 498 522 0.92

4 5 0.056 4.4e+02 0.8 1.0 88 154 555 615 530 630 0.47

5 5 2.2e-70 1.7e-66 226.1 0.6 199 408 624 828 610 828 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	4	3.1e+04	-5.8	15.7	66	163	204	296	99	345	0.59
2	5	4	3.1e+04	-8.0	9.7	70	160	297	372	252	409	0.37
3	5	4.9e-08	0.00039	20.8	0.0	1	21	498	518	498	522	0.92
4	5	0.056	4.4e+02	0.8	1.0	88	154	555	615	530	630	0.47
5	5	2.2e-70	1.7e-66	226.1	0.6	199	408	624	828	610	828	0.96

Sequence Information

Coding Sequence: ATGTCGGAGCAGAACGGGCCCCCGGAGGGCCCAGGCTGGTGGCCTCCGGCCCAATCCTGGAAGTCGTCGTCGGCCGCTGCGAGACCAGAAGCCGGAAAAAACGTATCTGTGACCACCATCAACGTTCCACCAGCCCACGAAATGCATGATGGTAAAAATGTTAAGTATTTGGGCGGTCGGAACGGTGTGACGGTGTCCGTTGTGTCCGGATGCGGTACCGGAAATGAACCCGAAAATGACGGAGCGGATAGCGACGGTGAAGTTAGCAAGATCGACTTCCGGGGAGTAAATTTACgcacgaagaagaagagggacGCGCCAGAAGGCCAGGAAAGCGATGCCAGCACCGTTACAGAGGCGATGCTACAGCAACCAGAACGTCCTATGTCCTGGGAAGGAGAACTTTCCGACCAGGAAATGTCTTCAAATACAATTACTAATCAAGACCATGAAGAAACTTCAATGGAAGGAGTTCAAGTGTGCAGTGCGAGCCCAGGACCAGCACACGCACCCCAAGAGCCCAAATTTCCTATAAAACTTGAGCCAGATTTTCGCTCAAGCCCAGCCCCACCTCTAGGACCCCCAAATGATACAAACCTATCAAACAcccaacaacaacaacaacaacaacaacaacaacaacagcaacaacaacaccAACACAATATCGACGGACTTGAGCAAAACCAACAAAGCGATTTGCCATTACTTGTTGGAAAACTACTCGGAGGATATAACAACGCTACTCCTAATCACAGCCCAGTTCTCAACCCAAGACATCATCTGACCAAACATAGCCACACGAGATCACAGGTTCCATCGCCAGATTCGGCGATCCATTCAGCCTACAGTGTATTTAGCTCCCCTACCCAAAGCCCACATGCTGCTCGACACTCAGCGCTTGGAGCTGGAAGCCCTGTGCCGTCTTCATCGTTGTCACTCTCACGCCACAGTTTCAATAATTCCACATCCTCGCTTTCCTTGTCGCTATCACATTCGCTGTCCCGAAATAACTCGGATGCATCCAGCAGCTGTTACAGCTATGGGTCTCTAAGCCCGCCGACACATTCGCCTGTGCAACAACCGAGGCACTCTCACTCGCATACTTCGCATCCTCATCATCAGGTCGGAGCACAGGGTAGCCCTCTGCATTTGCCAGTATCTCATCACTATTCGACAACAAATTCAGAGCTTTCTGAAGGGTTGAGTGAGGACCAGGAAGACTGTAAGATAGCGCCAGCTACGGCGGGAATTTCCACTAGGCAACAGCTCATTAATAGCCCCTGTCCAATCTGCGGTGATAAAATCAGCGGCTTTCATTACGGTATATTCTCGTGCGAATCATGCAAAGGATTCTTCAAGAGGACCGTACagaacagaaaaaattatgtCTGCCTTAGGGGAGCCGGATGCTCGGTTACTGTAGCAACACGAAAAAAGTGCCCTGCTTGTAGATTTGATAAATGCCTGAATATGGGAATGAAGTTGGAAGCTATTCGAGAAGATAGAACTCGAGGAGGCAGAAGTACCTACCAATGCAGTTACACGCTACCAGCAAATTTGGTAGGCTGTACTTCCGGCGGATTACCTGGCGACAAAATGGCTGGCGGAACATGCAGCCCTGCACCCCCTGGATACGAACATCACCATTCGGCGAGGCACCATTCTAATCATTCGCATAAACTTCACGTTGTGCCGCAACTGTTGCAAGAAATTATGGACGTTGAACATTTGTGGCATTATAATGACAATGATAGAACTACTAGTGCCCAAAGCAGTGGCAGCAGCAGTAAATCTGAACAGCCTAGGCCGAGCTCTGCGGGACCTCAAAATACCGAACATGAACAACACCCACCTAGTAATGCTAATAGTAACACAAACCCTTCGCAGCATCCAGACTTTTTGTCTAATCTGTGCAATATCGCAGATCATAGACTTTATAAAATCGTTAAATGGTGCAAGAGCTTGCCCTTATTCAAAAACATTTCAATTGATGATCAAATTTGTCTTCTTATAAATTCTTGGTGCGAATTGTTGCTGTTCTCATGCTGCTTTAGAAGCGTTAATACTCCGGGAGAGATTAGAGTCTCACTTGGGAAGTCAATTACGCTTGAACAAGCCAGACAACTCGGTCTTGCTAGTTGCATCGAAAGAATGTTGGCTTTCACCAACAACCTTAGGCGATTGAGAGTCGACCAATATGAATACGTCGCAATGAAGGTCATTGTTTTGCTAACTTCTGACACAAGCGAGTTGAAAGAGCCAGAAAAAGTTCGAGCATCTCAAGAGAAAGCGTTGCAAGCATTGCAGCAATATACAATTGCAATGTATCCAGAAATGCCAGCAAAATTTGGTGAACTCCTTCTTAGGATCCCAGACTTGCAGCGAACATGCCAAGCAGGAAAGGAGCTACTCAGTGCTAAACGAGCTGAGGGAGAAGGCAGTTCGTTCAATTTATTAATGGAACTGCTCAGAGGGGACCACTGA
Protein Sequence: MSEQNGPPEGPGWWPPAQSWKSSSAAARPEAGKNVSVTTINVPPAHEMHDGKNVKYLGGRNGVTVSVVSGCGTGNEPENDGADSDGEVSKIDFRGVNLRTKKKRDAPEGQESDASTVTEAMLQQPERPMSWEGELSDQEMSSNTITNQDHEETSMEGVQVCSASPGPAHAPQEPKFPIKLEPDFRSSPAPPLGPPNDTNLSNTQQQQQQQQQQQQQQQHQHNIDGLEQNQQSDLPLLVGKLLGGYNNATPNHSPVLNPRHHLTKHSHTRSQVPSPDSAIHSAYSVFSSPTQSPHAARHSALGAGSPVPSSSLSLSRHSFNNSTSSLSLSLSHSLSRNNSDASSSCYSYGSLSPPTHSPVQQPRHSHSHTSHPHHQVGAQGSPLHLPVSHHYSTTNSELSEGLSEDQEDCKIAPATAGISTRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAGCSVTVATRKKCPACRFDKCLNMGMKLEAIREDRTRGGRSTYQCSYTLPANLVGCTSGGLPGDKMAGGTCSPAPPGYEHHHSARHHSNHSHKLHVVPQLLQEIMDVEHLWHYNDNDRTTSAQSSGSSSKSEQPRPSSAGPQNTEHEQHPPSNANSNTNPSQHPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSVNTPGEIRVSLGKSITLEQARQLGLASCIERMLAFTNNLRRLRVDQYEYVAMKVIVLLTSDTSELKEPEKVRASQEKALQALQQYTIAMYPEMPAKFGELLLRIPDLQRTCQAGKELLSAKRAEGEGSSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00174217;
90% Identity: iTF_00938835;
80% Identity: iTF_01414296; iTF_01414204;