Tmol005738.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Tenebrio molitor
Gene Symbol
tfap2e
Assembly
GCA_963966145.1
Location
OZ014539.1:8418011-8422104[+]

Transcription Factor Domain

TF Family
AP-2
Domain
TF_AP-2 domain
PFAM
PF03299
TF Group
Basic Domians group
Description
Activator protein-2 (AP-2) transcription factors constitute a family of closely related and evolutionarily conserved proteins that bind to the DNA consensus sequence GCCNNNGGC and stimulate target gene transcription [PMID: 2010091, PMID: 1998122]. Four different isoforms of AP-2 have been identified in mammals, termed AP-2 alpha, beta, gamma and delta. Each family member shares a common structure, possessing a proline/glutamine-rich domain in the N-terminal region, which is responsible for transcriptional activation [PMID: 2010091], and a helix-span-helix domain in the C-terminal region, which mediates dimerisation and site-specific DNA binding [PMID: 199812]. http://www.ebi.ac.uk/interpro/entry/IPR013854
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 0.75 2.1e+04 -4.3 0.2 169 181 109 121 104 124 0.81
2 2 9e-83 2.5e-78 263.1 0.0 1 196 197 387 197 388 0.97

Sequence Information

Coding Sequence
ATGCTGCCTGTTACGGATGTGGAGCGGCTGACGGCCGGCGGTCATGGTTCACTAGCTCTGAGCGGCAGTTCGCCGGGATACGGCGCGGGCGGCTCCGGAGCGCACCATCGCGGCTCCGGGGGCCTCCACCACGGCTCTGCCATGCAACACCAGCTGCCGCAGCCGGACTTCCAGCCCCCGTACTTCCCGCCGCCGTTCCACCACCCCCCTAGTCCGCCCCCGCAGCAGCACCTCGAGTACCTCGCCGACCCGTACGGCGGCCTCAGCGGCCTCCACCACTACAACCAACTGGGGCTCCGGCCTCGGGAAGGCGACCCGAACCACACGCACGTGAGTCAGTTGGGCCATGGGGCCGGGTTCCCGTACAGCACGGCGCCGGGCGGCGGCCGTCCGGATTACTCCGTAACGACCCCACAAAGACCCCACGATGACCCCCTGTCGCTGCACCAGGCGCTGGGGCAGGCGGTGGAAGAGGCCCAGGGCGGCATCGACGACAACACCGGCTTCATATCCGACTTACCTCTGTTAAAAAGTATGAAAGGGGGCAAGGACCACGGCGGAGGCGCGATGGTGTCACCCAGCGACGTCTTTTGTTCGGTTCCTGgtcgtctctctctcctctCCTCAACCTCAAAGTACAAAGTAACCGTAGGCGAAGTACAACGGCGTTTGTCGCCCCCGGAATGCCTCAACGCGTCGCTCCTCGGCGGGGTGTTGAGGAGGGCCAAGAGCAAGAACGGCGGACGCATCCTTAGGGAGAAGCTGGAAAAGATCGGTCTCAACCTTCCGGCGGGGCGGCGAAAAGCCGCCAATGTGACTTTGTTAACTTCGTTAGTAGAGGGTGAGGCCATCCACTTAGCCAGAGACTTCGGTTATGTGTGCGAGACGGAATTTCCCGCGAGGCAAGTGGCGGAGTATTTGCTCAGGCAACACGGAGAGACTCCTCGAAGGAAGGAACTCCTCCAGGCCACCAAACAAATCACGAAAGAATTGATGGATCTCTTGAACCAGGATCGGTCACCTTTGTGCAATACTAGGCCGCAAATTCTTCTAGACCCCTCGATACAACGACATTTAACGCACTTTTCGCTCATTAGCCATGGATTCGGCAGTCCAGCCATCGTGGCCGCTCTGACCGCCATCCAGAACTTTTTAAGTGAATCGTTGAAGCATTTAGACAAAATGTTTCCCAACCAAAATACGCAACAAGGACAGGCCATGTTAGTTACTTCGTCTCTAGACAAAGCCAAATTAGAGGACAAGAAGTGA
Protein Sequence
MLPVTDVERLTAGGHGSLALSGSSPGYGAGGSGAHHRGSGGLHHGSAMQHQLPQPDFQPPYFPPPFHHPPSPPPQQHLEYLADPYGGLSGLHHYNQLGLRPREGDPNHTHVSQLGHGAGFPYSTAPGGGRPDYSVTTPQRPHDDPLSLHQALGQAVEEAQGGIDDNTGFISDLPLLKSMKGGKDHGGGAMVSPSDVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRILREKLEKIGLNLPAGRRKAANVTLLTSLVEGEAIHLARDFGYVCETEFPARQVAEYLLRQHGETPRRKELLQATKQITKELMDLLNQDRSPLCNTRPQILLDPSIQRHLTHFSLISHGFGSPAIVAALTAIQNFLSESLKHLDKMFPNQNTQQGQAMLVTSSLDKAKLEDKK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00414738; iTF_00752627; iTF_00277829; iTF_01128001; iTF_00168896; iTF_00986820; iTF_00267813; iTF_00270729; iTF_00272138; iTF_00853643; iTF_01291148; iTF_00927188; iTF_00269429; iTF_00003452; iTF_01293248; iTF_00078063; iTF_00248614; iTF_01366025; iTF_00167396; iTF_01565934; iTF_01311250; iTF_01567507; iTF_00841529; iTF_01329465; iTF_01479805; iTF_00764353; iTF_00019876; iTF_00964812; iTF_00130165; iTF_00998231; iTF_00903786; iTF_00631201; iTF_00631819; iTF_00620273; iTF_00629497; iTF_01058799; iTF_01058051; iTF_01185860; iTF_01096295; iTF_01400040; iTF_01370672; iTF_00369267; iTF_01126037; iTF_00920343; iTF_01535519; iTF_01106863; iTF_00115389; iTF_01344592; iTF_00110214; iTF_01295687; iTF_01121260; iTF_01162770; iTF_01441622; iTF_00415579; iTF_00328842; iTF_00327545; iTF_00755136; iTF_00646485; iTF_01226298; iTF_01013931; iTF_00394939; iTF_00721692; iTF_01368703; iTF_00788209; iTF_00398518; iTF_01283944; iTF_00853642; iTF_00003451; iTF_00641075; iTF_00421873; iTF_01286884; iTF_01277364; iTF_00639211; iTF_00870240; iTF_00955993; iTF_01120560; iTF_00814087; iTF_00929258; iTF_01021908; iTF_00813403; iTF_01098171; iTF_00980614; iTF_00740489; iTF_00137581; iTF_01257647; iTF_00001681; iTF_00136498; iTF_00625844; iTF_01097108; iTF_00464342; iTF_00626751; iTF_00243899; iTF_00739611; iTF_00330238; iTF_00025724; iTF_01105254; iTF_01046796; iTF_00791765; iTF_00386872; iTF_00458549; iTF_00735166; iTF_00056226; iTF_00910205; iTF_00829917; iTF_01238244; iTF_00443630; iTF_01186703; iTF_00195635; iTF_00375945; iTF_01306920; iTF_00413171; iTF_01351326; iTF_00950399; iTF_00949480; iTF_00030688; iTF_00029879; iTF_00031482; iTF_00433728; iTF_01498563; iTF_00307257;
90% Identity
iTF_01311250;
80% Identity
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