Spla009254.1


Basic Information
Transcription Factor Domain
Sequence Information
Similar Transcription Factors

Basic Information

Insect
Salpingus planirostris
Gene Symbol
tfap2e_1
Assembly
GCA_949788335.1
Location
OX460923.1:2720789-2727346[+]

Transcription Factor Domain

TF Family
AP-2
Domain
TF_AP-2 domain
PFAM
PF03299
TF Group
Basic Domians group
Description
Activator protein-2 (AP-2) transcription factors constitute a family of closely related and evolutionarily conserved proteins that bind to the DNA consensus sequence GCCNNNGGC and stimulate target gene transcription [PMID: 2010091, PMID: 1998122]. Four different isoforms of AP-2 have been identified in mammals, termed AP-2 alpha, beta, gamma and delta. Each family member shares a common structure, possessing a proline/glutamine-rich domain in the N-terminal region, which is responsible for transcriptional activation [PMID: 2010091], and a helix-span-helix domain in the C-terminal region, which mediates dimerisation and site-specific DNA binding [PMID: 199812]. http://www.ebi.ac.uk/interpro/entry/IPR013854
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1.1e-82 1.9e-78 262.8 0.0 1 196 236 426 236 427 0.97

Sequence Information

Coding Sequence
ATGGCTTTTCGGCCGGCTCGGCTCGGCGGCCGTTTTCGTGTCGAGGGGCCAGGCTGCGGGCAGGTCGCCTCGAGCAGAGTCGGAATGCCGTCAGGCAAGTGCACGCCCTCATCTCCAGGTCCCCCGGGCCCCCTTCAGGAGCGTCTCACGGCGGGCGGTCATGGCTCTCTGGCTCTGAGCGGCAGCTCCCCAGGTTACGGCGCCGGCGGCTCGGGGGCGCACCACCGCAGCTCCGGCGGCCTCCACCACAGCTCCGCCATGCAGCACCAGCTGCCCCAGCCGGACTTCCAGCCCCCGTACTTCCCGCCGCCGTTCCACCACCCGCCTAGTCCGCCGCCCCAGCAGCACCTGGAGTACCTGACCGACCCCTACGGCGGGCTGTCCGGCCTCCACCACTACAACCAGCTCGGCCTGCGACCCAGAGAGGGCGACCCCAATCACACGCACGTGAGTCAACTGGGACACAGCGCTGGCTTTCCCTACAGCAGCGCCCCGGGCGGGGGCCGATCGGATTACTCGGTCTCGGCGCCCCAAAGGCCTCACGACGACCCCCTGTCCCTGCACCAGGCCTTGGGCCaggccgtcgaggaggcccAGGGCGGCATCGACGACAACACCGGCTTCATATCGGATCTCCCCCTCCTGAAAAGTATGAAAGGGGGCAAGGACCACGGCGGCGGGGCGATGGTGTCGCCGAGCGACGTCTTCTGCTCGGTGCCCGGGCGCCTGTCGCTCCTGTCGTCCACCTCCAAGTACAAAGTGACGGTGGGCGAGGTGCAGCGGCGGCTGTCGCCCCCCGAGTGCCTGAACGCGTCGCTCCTGGGCGGCGTGCTGCGGCGGGCCAAGAGCAAGAACGGCGGGCGCATCCTGCGCGAGAAGCTGGAGAAGATCGGGCTGAACCTGCCGGCGGGTCGGAGAAAAGCCGCCAACGTGACGCTGCTCACGTCCCTGGTCGAGGGGGAGGCGATCCACCTGGCGCGCGACTTCGGCTACGTGTGCGAGACGGAGTTCCCGGCCCGCCAGGTGGCCGAGTACCTGCTGCGGCAGCACGGGGAGACGCCCAGGAGGAAGGAGCTGCTGCAGGCGACCAAGCAGATCACCAAGGAGCTGATGGACCTGCTGAACCAGGACAGGTCGCCGTTGTGCAACACGCGGCCGCAGATCCTGCTCGATCCGTCAATACAGCGGCACCTGACCCATTTCTCGCTCATCAGCCACGGCTTCGGCAGTCCGGCCATCGTGGCCGCCCTCACGGCCATACAGAACTTTCTAAGTGAATCTCTGAAACATTTAGATAAAGTGTTTCCTAACCAAAATACTCAGCAGGGACAGGCCATGCTAGTTACGTCGTCCTTAGACAAAGCCAAATTAGAGGACAAGAAGTGA
Protein Sequence
MAFRPARLGGRFRVEGPGCGQVASSRVGMPSGKCTPSSPGPPGPLQERLTAGGHGSLALSGSSPGYGAGGSGAHHRSSGGLHHSSAMQHQLPQPDFQPPYFPPPFHHPPSPPPQQHLEYLTDPYGGLSGLHHYNQLGLRPREGDPNHTHVSQLGHSAGFPYSSAPGGGRSDYSVSAPQRPHDDPLSLHQALGQAVEEAQGGIDDNTGFISDLPLLKSMKGGKDHGGGAMVSPSDVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRILREKLEKIGLNLPAGRRKAANVTLLTSLVEGEAIHLARDFGYVCETEFPARQVAEYLLRQHGETPRRKELLQATKQITKELMDLLNQDRSPLCNTRPQILLDPSIQRHLTHFSLISHGFGSPAIVAALTAIQNFLSESLKHLDKVFPNQNTQQGQAMLVTSSLDKAKLEDKK