Basic Information

Insect: Ecitophya simulans
Gene Symbol: tfap2e
Assembly: GCA_027574965.2
Location: JAODGE020021864.1:1-4169[+]

Transcription Factor Domain

TF Family: AP-2
Domain: TF_AP-2 domain
PFAM: PF03299
TF Group: Basic Domians group
Description: Activator protein-2 (AP-2) transcription factors constitute a family of closely related and evolutionarily conserved proteins that bind to the DNA consensus sequence GCCNNNGGC and stimulate target gene transcription [PMID: 2010091, PMID: 1998122]. Four different isoforms of AP-2 have been identified in mammals, termed AP-2 alpha, beta, gamma and delta. Each family member shares a common structure, possessing a proline/glutamine-rich domain in the N-terminal region, which is responsible for transcriptional activation [PMID: 2010091], and a helix-span-helix domain in the C-terminal region, which mediates dimerisation and site-specific DNA binding [PMID: 199812]. http://www.ebi.ac.uk/interpro/entry/IPR013854
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 1.5e-82 3.4e-78 262.4 0.0 1 196 188 378 188 379 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	1.5e-82	3.4e-78	262.4	0.0	1	196	188	378	188	379	0.97

Sequence Information

Coding Sequence: GAGAGACTGACGGCCAGCGGGCACGGTTCGCTGGCGCTGAGCGGCAGCTCGCCGGGctacggcgccggcggcagcggcggccatCACCATCGCGGCGCCTCGGCGGTGCAccacggcggcgcgatgcagCACCAGCTGCCGCAGCCGGACTTCCAGCCGCCGTACTTCCCGCCGCCGTTCCACCACCCGCCcagcccgccgccgcagcagcaccTCGAGTACCTCACGGATCCGTACGGCGGCCTCTCCGGCCTGCACCACTACAATCAGCTGGGCCTGCGGCGCGAGACCGACCCCAATCACACGCATGTGAGTCAACTCAGTCATGGGGCGAGCTTCCCGTACGCCGGCGGGCCGGGCGGCCGCCCCGATTACGGCATCCCGCAGAGGGTCTCCTCGCACGACGACCCATTGTCCCTGCACCAAGCCCTGGGGCAGGCCGTGGAGGAAGCCCAGGGTGGCATCGACGACAACACGGCGTTCATTTCCGACCTACCTCTTCTGAAAAGCATAAAGGGCAAAGaccacggcggcggctcgaTGGTGTCGCCCTCGGACGTCTTCTGCTCGGTGCCGGGCCGCCTCTCCCTGCTCTCCTCCACGTCCAAGTACAAAGTGACCGTCGGCGAGGTGCAGCGCCGGCTGTCGCCGCCGGAGTGCCTGAACGCGTCActcctcggcggcgtgctgcgcCGCGCCAAGTCCAAGAACGGCGGGCGGCTGCTGCGCGAGAAGCTCGAGAAGATCGGACTGAACctgcccgccggccggcggaaAGCCGCCAACGTCACGCTGCTCACGTCGCTGGTGGAGGGCGAGGCGATCCatctcgcgcgcgacttcggcTACGTCTGCGAGACGGAGTTCCCCGCGCGCCAGGTCGCCGAGTACCTCATCCGCCAGCACGGCGAGTCCGTGCGCCGCAAGGAGCTGCTGCAGGCCACCAAGCAGGTGACCAAGGAGCTGATGGACCTGCTCAACCAGGACCGCTCGCCGCTGTGCAACACGCGGCCGCAGATCCTCCTCGATCCGTCCATCCAGCGCCACCTCACGCACTTCTCGCTCATCTCGCACGGCTTCGGCTCGcccgccatcgtcgccgcgctcacCGCCATCCAGAACTTCCTCAGCGAGTCGCTCAAGCATCTCGACAAGCTGTACCCCAACCAGGGCGGGCAGGGCCAGCCGATGCTCGTCACGTCGAGCCTCGACAAGGCCAAGCTGGACGACAAAAAGTGA
Protein Sequence: ERLTASGHGSLALSGSSPGYGAGGSGGHHHRGASAVHHGGAMQHQLPQPDFQPPYFPPPFHHPPSPPPQQHLEYLTDPYGGLSGLHHYNQLGLRRETDPNHTHVSQLSHGASFPYAGGPGGRPDYGIPQRVSSHDDPLSLHQALGQAVEEAQGGIDDNTAFISDLPLLKSIKGKDHGGGSMVSPSDVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRLLREKLEKIGLNLPAGRRKAANVTLLTSLVEGEAIHLARDFGYVCETEFPARQVAEYLIRQHGESVRRKELLQATKQVTKELMDLLNQDRSPLCNTRPQILLDPSIQRHLTHFSLISHGFGSPAIVAALTAIQNFLSESLKHLDKLYPNQGGQGQPMLVTSSLDKAKLDDKK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01409635;
90% Identity: iTF_00631201; iTF_01286884; iTF_01098171; iTF_01097108; iTF_01400040; iTF_01058799; iTF_01058051; iTF_00369267; iTF_01185860; iTF_01096295; iTF_00903786; iTF_01370672; iTF_00620273; iTF_00920343; iTF_01126037; iTF_00629497;
80% Identity: -