Basic Information

Gene Symbol
-
Assembly
GCA_945859765.1
Location
CAMAON010000023.1:1219656-1229454[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 23 0.011 0.61 10.9 0.6 3 23 687 708 686 708 0.96
2 23 0.067 3.8 8.4 0.3 1 21 1079 1099 1079 1100 0.96
3 23 7.7 4.4e+02 1.9 0.3 1 22 1142 1163 1142 1165 0.82
4 23 0.0064 0.37 11.6 0.5 3 21 1176 1194 1174 1195 0.95
5 23 1.7 95 4.0 0.0 3 23 1204 1225 1202 1225 0.88
6 23 0.02 1.1 10.0 0.2 3 23 1246 1267 1244 1267 0.96
7 23 0.0043 0.24 12.1 3.5 1 23 1273 1296 1273 1296 0.95
8 23 0.14 8.2 7.3 0.0 1 23 1322 1345 1322 1345 0.90
9 23 0.022 1.2 9.9 3.4 1 23 1350 1372 1350 1372 0.97
10 23 0.0099 0.56 11.0 0.2 1 23 1378 1401 1378 1401 0.95
11 23 0.0027 0.15 12.8 1.3 1 23 1414 1436 1414 1436 0.97
12 23 0.0002 0.012 16.3 1.8 1 23 1485 1508 1485 1508 0.97
13 23 0.0014 0.079 13.7 1.0 1 23 1568 1591 1568 1591 0.96
14 23 0.0011 0.061 14.0 2.0 2 23 1614 1636 1613 1636 0.95
15 23 0.032 1.8 9.4 0.1 2 23 1642 1664 1641 1664 0.94
16 23 0.015 0.83 10.5 0.2 1 21 1709 1729 1709 1730 0.95
17 23 0.0014 0.08 13.7 0.6 1 23 1740 1762 1740 1762 0.93
18 23 0.0001 0.0057 17.3 0.3 2 23 1853 1875 1853 1875 0.93
19 23 3.8e-07 2.2e-05 24.9 1.4 3 23 1882 1902 1881 1902 0.98
20 23 0.0078 0.45 11.3 0.4 1 23 1921 1943 1921 1944 0.95
21 23 0.045 2.6 8.9 0.0 1 23 1965 1987 1965 1987 0.98
22 23 0.015 0.86 10.4 1.0 1 23 1993 2016 1993 2016 0.95
23 23 0.00036 0.021 15.5 0.7 1 23 2024 2047 2024 2047 0.96

Sequence Information

Coding Sequence
ATGAATGTGAATTATGATCGTGTTTGTAGACTGTGCTTGTCATCTAGAGGCGAATTACTGCCGATTTTCCCTACCACCAGTTCGGATGACTCGGAACCTCCCGTCCTCGCTTCGAAAATCAAGGATTGTGTCTCTGTCGAGATTAACGAGAATGACGACCTTCCGACAAATGTCTGCAAGAAATGCATGGACAATGTCAATAACTGGCACATATTTAAGTCAGTATGTGTGAAGGCCCAAAACAAACTAGAATCTTTTGTAAAAGATGGCAGCCAACTAGAAGAGGTGAAGATAAAAAATGAACCTTTATCAGATGAGGCTTATGATGATGGAGTAGTTATTGATGGATCATATCCTGACATTGAGAATGGTGGGAGCAAATTGCAGCCTGAAGGCCCACCAATCTTGGCTTCGTTAGGGCTTACACCGAGGAGTGATAAGAAATTAGATCCTCGTATGGATTGGCATCGAGTGCATGCAATATTGGATATAGTTCAAGACGATGATGTAATCGATTCACTGCAAAATACAGAGGAGTTTGACGACCTGCAACATTCCGATCACAACTCGGACACAGAAGGTGATTTGCAGTCGGACATTGATGAGGAATATGTGGACTCCAAAGACAGCTATAAGTGCAAAAATGGAAGACTCATGGCGAAATTCTTAAACACAGATATTACAAAAAACTCACAAAGAGAATGTGAATCTGTTGTAAATTTTAAAAAGAGGAAGTTGACCTCAAAAAATTGTCCCCAACCGAGATTTGCATGGCAAATGTTTTTCACAGAGGATCTGTTGAATCATATAGTCGAATCTACAAACGCAAATATATCATCCAACGTCATGAATATCCTCGAATTGAAGACTTTGATAGGCATTTTGTATTTCCACGGCATTATGAGACCGACTCACACTAAACTCTGTGACCTATGGCATAGTGATTATGGAATCAACTGTGTCATTGAGTCTATGAAGTATGAGCGGTTTAAATTTTTACTTCAAAACATTAGTTTCAGTCAAGAGAGTGACGATAGCATTATACAGTCGGACGTTATGAAGCGAATGCGTGAAGTGTTTGAGATATTTGCTATGAATTGTAGAACAGTTTTCAATGTAGATAGAATAGCTGTCATCGATGAGATCATTGTGCCGGTTTACGGGCCTTGTCCGTTCCGATACAATATTGATAGAAAGCCTACAAAGTCTGGCGTTAAGTTGGCACTCCTAGTGGACCCGTCCAATTTCTACATAAGTAATGTCGATGTAATTGTGGACCGTTATTTCAGTGCTGAAGATGTTACAAAAAAAATGGTTCAACATTTGGAAGGTTCATGGCGAACAGTCCTAATGGACAGTTGGTTTACGTCTTTAAAATTGTTGGAAACATTGAAAACCGAACACAGTTTGTTTAGCGTTGCCGCAGTAAAACCGACCGAAGAGTTTATACCGCCAACGTTTTTTTCCCAATTTCGAAAACCTCAATCAGTTATGACTGGATATCTAAACGATGAATGTATTTTATCTTCATATGTTACATCTCAATCGAAATCAATTAATGTAATGACAAATGACCCGGATTATGTAACCAATAAGTATAGAAATGTAGTAAAATTTTACATGAAGAATAAATCTTGCGTTGAAGTCGTGGACGTACTAATGCATTACTATACGACCATGCAACATACGAACAGTTGGACGATCTCATTGTTTTTTACACTTTTGAATATAGCCGCTGTGAATTCGCAAGTCGTTTGGAGTTCGGCAAACAGTTCGTGTTTAATACAAAGACGGTTGTTCCTGAGAGAGCTGGCTTTGAGTCTAATGCAAAATTCATATGTGAATGTAGAATTGAAATCTGTGAAACAGCAGAAGACATCGCGTTTCGAAGATGGTGCAGAGAGTGACAAAGAAGAAGAAGACGATGAAGAGATGAACGAAGCTGGTGACCAGTACCCCCCTGTCGCGAACATGCCCGAGGTATCGATAACAGTGATGCGACCCACCGGAGAGACCTTACAGTCTCGACAGGGAATACAACAGCTCGCATCTAAGGATTGTCTTGTATGTGGACGAGCGTACAGATACTCACATAATGCTAGACGACACGAATTGACTGCCCACAGTTTTGATAGGTATACAAATAAAATTAAACCCAAAAAAGAGAATTCACATGTAATGCTACCAAAACTTAGACCGAATCCATTTAATCCTAAAGCGCGAATGATGCCCAACCCCATTAGCCACAAAATGCAATTTATGCCCAAGAATGTACCTATTAAACAAATGCCAAGAGTTGTTATCCCACCGAAACCTGTACCCATAAGGACTAAACCACATAACAATTTACCGTATCCTCTTCGAATAAAGGCTTTAAAGGATTTGCAAATTAAGAAAAAGGAGCCAGAAATATTGAAAACTCTTTTGACCACTAAACCGGAAGTACTCGTTTCCGAACCGGAGATAATAAATTCTGGCCCCGAAAGCCCTGAAACATTGATTTCAGAGCCAGAAATTGCATCGTTTCAAGTGGAAGCCATACTTTCCGAGCCAGATGTTTACGATCAACAGCAAGATGACCAAGAAAACGGGGAAAATTTGGACAACAATCAAGGGCACAATTATGACACTGTCGATATGGATTCTGATAATGAAATTGAAATTGCAAGGCAACGAGAGAACGACAACAATGTCGACGAGAACAATACGGGTCAAGACGGTGAAGGTAATTCAATAGAAATCAATGAAAATAATATTGAAGGCCAACAGAGCGATAAAGACGAGGACGAGGAAATGGGTGATAGTCAGGACGGTGTGGCCGAATCCAAAGAAGATGAAAATAAAAATGGTGAAACATATGACGATCAAGAACAGCAACAAGGGGACAACGACGAAGAATATGACGATGATCTCCCACCTATGGACATAACACCTGTTGTTGAAATCAATGAGGACATGCAGACGAACTCATTTAATAGCGAAATAAACGAAGACGATGAAGATTTAGACATATCGGGCGAAGCTAACGATACCGTTGATGGTGAAGAGAATGACGCGAAAGATCTCGATCCGGACAAGGTTTATGTTACGAAAACACAGAGAGACTTTATTAATAAGTATCGCGACATCATAGAGCAAATAAACACCAAACGGTGTCTTTGTTGTGACAGGGAACACCCTCGAAGGAAAGCGGTGATTCAACATCTGCAGAAAAATGGTCATAAGGTACCGAAACATACGTGTTACAATTGTGTCGTTACATTTAGCCATATCGGTGCACTGCTCAGTCATATGAGAGCAAACGTTTGCACGGATTTGTGGAAGATAATTTTCGACGAAAATGGTATTACGGATGATATGGTTATAGAAGATGAACCAAAAGATGCCAAAGTTCAATATAAAGACATTTTTAATGCTCGTTCTTATGCTTGTAAACTATGCCCTGCCAAATTCCAACTTAAACAATTTATTATGAAGCATGTTTTGGATGTCCACGAGGACGGACAGTCTATGGTGCCAATGGCGTGTGTCCATTGCGGTTCTAGGTTCAAAGACAAGGCCATGTGGAAGAAACATATCCGCAATGGTGAGTGTACGGTTTACATAGCGTGCGATTTGTGTCCTGAAAAATTTATCAGCATGCAAGATTTCAGTGAGCACGCCTTAGCCACACACGCTGGTAATTTCGAACAAAATGAAAATCAGAATAAATGTGTCGACGGAAGACCGACCGATTGCCCTCTCTGCGGGAAGAAGAACAGTAGCTATCCAAATTTGGTGAAACATTTAAAGATTATACACAACGAAGAGAAACCTCATTACTGTCAACACTGTGATTCTAAGTTCGAACAGGCCACCGACCTCAACAAACACATTTATATGGAGCACTCTGACCGCGTTTTGGGCTTACAAACCACCGAACCTGATATGAGTATTGTCAAGGAGGAGACTGAAGAATATCACTACTCATGCACTGAGTGCAATGCTATATTCGAAACGGTCGACGCTTGGACCGATCATCAGGTCGCCGAACATAACCAGGTTGCACATCACTGCGATCAATGCGAGAAAAAGTTCTTGCGGCCATCTGAACTCGCCGAGCATAAGAATACGCACTTGCGTGTCAAGTTCTATCCGTGTAGTGTCTGTCCAAACTCGTATAGCACTCCGCAGAAATTGTCTGAGCACGTCCAACAAAGTCACCCCGGAGCAGCTTCATACGCTGCAGCCGATTCCGAATTCTTTTGTGACATCTGCATTCGATCGTTTAAGAGTCGCCAGGCTTATTCCAATCATATGCGTATACACGCTAAAGTGCCCACCACTAATAGGAAACCGGGAGATCCAAAAGGATTCTCCCCGCAGATCATCGGAAAGCCTATTAGACAATTCCCGCAAATCGTTCCCGGTTTTCCCTCGTTCAAGCCAAACTGTAATGTTCCTAACGCGCCTTATTCGTGCGATATATGCGGAAAAGGTTTTATGCACAAGAAAAATATATGGAAGCACAAAAAGGTGTTGCACGCTGATATTATTAATGATAGGAACGACAGTGAGGAGAACACTATGCACGCTTCCACCGAAGAGGACGAGTACAATGTCGATGAAAATGGAATCGCTTTGTCCACGCCACAGTTCAATAGTTTTAACTTTTCAAGTTTTACTAACAACACACCCGTTCAACAGCCAGACCCGATGCCGTACGTCTGTGATCTTTGCAGCAAGCGTTTCCCACTGAGAACCAGTTTGTGGAAACACAAACGAGCCAAACACGGCATAATTAATCCAGGAGGCGAGCCGCAGTCGGCCGGAGCCGGTAGCGGCGGCAGTAGTAGATCGAGTTGCACTATATGTAAAATTTCGTTCTCAGACAAGAAATCTTATTATCGCCACAGAAAGAACGTGCACAAATCGTCTACACAGATGTGTAAAATATGTGGAAAACCGTTAAGCACTACCCTCGAACTGTACGAGCACTTGAAAGCGGCTCACGCTCGAGAGTTGCTCGGCTATAACGCCAATCAAGGGTCGTCCAGTAGACCGCAAACGATTACGCAAGACTTGGATCCCGATTATGAAGCCGAAATGGATACGACCGATCCCGCGGCCGAGTACCAAGCGCGGTATCCTTGCGATACGTGCGGCAAACAATTTGTCGGACTACTCGCATTGCAAAACCATCAATGTCTTAATCAGAATTCGTCCGATCCGCAAACGTTTGATTGTGAAATTTGCCACAAGAGTTACACGTCGATTGCCGCATTAAAGAGCCACCGCGGTTGGCATTTGAGATCTCCGGACGGCAAAGCGGCCGCTAACAATTCAGGTTTGTGGATGCCACAACACAAGGTGACCAGTAAGGTCAGCAAATACGAAGTGGTCGATGCGGTGCAATTAGCCCGTGTACAGCACTCGACTCCAGCGGCGACCGTAGCCAAAAGGCGTCTGCCGCCAGAAGTCGAAGTGACAGTTGTCAATCCGAACAAAAAATTGCGCTCGGACGACTCGATGGAAATCGAACAGCAAAGCAACTTATCGGGCACCACAGAGGACAGATATTGCAATATATGCGACAAGGAGTTCACTAAGCGCGCGGCTTACCAGCGTCACATGGACGAAGTGCATCAACCGAATTCGGTTTTTTGTCCAGTTTGCGATAAGAGTTTTACGCGGAAATCTACTCTGCTAGTTCACATGAAGAAACATTACGAGGGAGGAGAGGGCAGTTCGGGGACTGCCGGACAAGTGGACGATGATAACTTTTCATGCGATCTTTGCGACGCACAGTACAATAGCGAGGCCGCGTTGAGGGCTCACCGCGAAAGGCATCACGGCGACGAATCTGGTGAATCTGAGGAGGAGGGCATAGCGAATATACTGCCTCCTGGCGAGTTCACTTGCACGCAGTGCGGTGACGGTGTGGCGACACCGCGAGACCTCATCGCTCACCGTTCCATGCACGCGACACCCACAAAGTTCTTCTGCAACATATGCAAGGTGTACTTCACTAGGGCGCTAGATCTCTCGTCGCACACGCGCGCGCGACACGCCGACAACGAGAAGGTTTTCTTCCCCTGTGCCATGTGCGATCGTTTCTACATGAACAAGAAGAGTTTGCAGCGACACATTGAGATGTCTCACTGA
Protein Sequence
MNVNYDRVCRLCLSSRGELLPIFPTTSSDDSEPPVLASKIKDCVSVEINENDDLPTNVCKKCMDNVNNWHIFKSVCVKAQNKLESFVKDGSQLEEVKIKNEPLSDEAYDDGVVIDGSYPDIENGGSKLQPEGPPILASLGLTPRSDKKLDPRMDWHRVHAILDIVQDDDVIDSLQNTEEFDDLQHSDHNSDTEGDLQSDIDEEYVDSKDSYKCKNGRLMAKFLNTDITKNSQRECESVVNFKKRKLTSKNCPQPRFAWQMFFTEDLLNHIVESTNANISSNVMNILELKTLIGILYFHGIMRPTHTKLCDLWHSDYGINCVIESMKYERFKFLLQNISFSQESDDSIIQSDVMKRMREVFEIFAMNCRTVFNVDRIAVIDEIIVPVYGPCPFRYNIDRKPTKSGVKLALLVDPSNFYISNVDVIVDRYFSAEDVTKKMVQHLEGSWRTVLMDSWFTSLKLLETLKTEHSLFSVAAVKPTEEFIPPTFFSQFRKPQSVMTGYLNDECILSSYVTSQSKSINVMTNDPDYVTNKYRNVVKFYMKNKSCVEVVDVLMHYYTTMQHTNSWTISLFFTLLNIAAVNSQVVWSSANSSCLIQRRLFLRELALSLMQNSYVNVELKSVKQQKTSRFEDGAESDKEEEDDEEMNEAGDQYPPVANMPEVSITVMRPTGETLQSRQGIQQLASKDCLVCGRAYRYSHNARRHELTAHSFDRYTNKIKPKKENSHVMLPKLRPNPFNPKARMMPNPISHKMQFMPKNVPIKQMPRVVIPPKPVPIRTKPHNNLPYPLRIKALKDLQIKKKEPEILKTLLTTKPEVLVSEPEIINSGPESPETLISEPEIASFQVEAILSEPDVYDQQQDDQENGENLDNNQGHNYDTVDMDSDNEIEIARQRENDNNVDENNTGQDGEGNSIEINENNIEGQQSDKDEDEEMGDSQDGVAESKEDENKNGETYDDQEQQQGDNDEEYDDDLPPMDITPVVEINEDMQTNSFNSEINEDDEDLDISGEANDTVDGEENDAKDLDPDKVYVTKTQRDFINKYRDIIEQINTKRCLCCDREHPRRKAVIQHLQKNGHKVPKHTCYNCVVTFSHIGALLSHMRANVCTDLWKIIFDENGITDDMVIEDEPKDAKVQYKDIFNARSYACKLCPAKFQLKQFIMKHVLDVHEDGQSMVPMACVHCGSRFKDKAMWKKHIRNGECTVYIACDLCPEKFISMQDFSEHALATHAGNFEQNENQNKCVDGRPTDCPLCGKKNSSYPNLVKHLKIIHNEEKPHYCQHCDSKFEQATDLNKHIYMEHSDRVLGLQTTEPDMSIVKEETEEYHYSCTECNAIFETVDAWTDHQVAEHNQVAHHCDQCEKKFLRPSELAEHKNTHLRVKFYPCSVCPNSYSTPQKLSEHVQQSHPGAASYAAADSEFFCDICIRSFKSRQAYSNHMRIHAKVPTTNRKPGDPKGFSPQIIGKPIRQFPQIVPGFPSFKPNCNVPNAPYSCDICGKGFMHKKNIWKHKKVLHADIINDRNDSEENTMHASTEEDEYNVDENGIALSTPQFNSFNFSSFTNNTPVQQPDPMPYVCDLCSKRFPLRTSLWKHKRAKHGIINPGGEPQSAGAGSGGSSRSSCTICKISFSDKKSYYRHRKNVHKSSTQMCKICGKPLSTTLELYEHLKAAHARELLGYNANQGSSSRPQTITQDLDPDYEAEMDTTDPAAEYQARYPCDTCGKQFVGLLALQNHQCLNQNSSDPQTFDCEICHKSYTSIAALKSHRGWHLRSPDGKAAANNSGLWMPQHKVTSKVSKYEVVDAVQLARVQHSTPAATVAKRRLPPEVEVTVVNPNKKLRSDDSMEIEQQSNLSGTTEDRYCNICDKEFTKRAAYQRHMDEVHQPNSVFCPVCDKSFTRKSTLLVHMKKHYEGGEGSSGTAGQVDDDNFSCDLCDAQYNSEAALRAHRERHHGDESGESEEEGIANILPPGEFTCTQCGDGVATPRDLIAHRSMHATPTKFFCNICKVYFTRALDLSSHTRARHADNEKVFFPCAMCDRFYMNKKSLQRHIEMSH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01387804; iTF_01388734;
90% Identity
iTF_01387804;
80% Identity
-