Sagr013158.1
Basic Information
- Insect
- Sycophaga agraensis
- Gene Symbol
- Lztr1
- Assembly
- GCA_018906755.1
- Location
- JACCIE010000080.1:510759-513850[+]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 1.6e-12 7.4e-10 39.3 1.5 3 108 352 486 350 488 0.86 2 4 0.68 3.1e+02 2.0 0.1 75 108 485 518 479 520 0.83 3 4 5e-18 2.3e-15 57.1 0.0 8 96 581 669 573 684 0.84 4 4 0.63 2.9e+02 2.1 0.1 76 101 683 708 678 717 0.79
Sequence Information
- Coding Sequence
- ATGGATAGTATAGCTGTTACTGAGTGTTTAACATTGGATTTTGGACCATTTGAAACAGTGCATCGATGGCAACAAATGCCAGAATGTGATGAGTTTGTTGGTGCCAGGCGAAGTAAACATACAGTTGTAGCTTATGAAGATGCAATTTATGTTTTTGGAGGAGATAATGGGAAACGAATGTTGAATGATTTATTACGATTTGATGTAAAAGAAAAATCATGGGGAAGGGCATTAGCTCATGGAGTTCCACCTGCTCCAAGATACCATCACTCTGCAGTAATCAATGGTTCTTCAATGTTTGTTTTTGGAGGTTATACAGGGGATATCCACTCTAATTCTAATTTAACTAATAAAAATGATTTATTTGAGTACCGTTTTAAAACTGGACAATGGGCTGAATGGAAATTTTTTGGAAAGACTCCAGTTGCTCGGTCAGCTCATGGTGCAGCAGTTTATGATAATAAGTTATGGATATTTGCTGGCTATGATGGCAATGCTCGTTTAAATGATATGTGGACAATATCTTTAATACCAGGAGATTCTAAAGTTTGGGAAAAGGTTGTACAGTCTGGTGATTGTCCACCAACATGCTGTAATTTTCCCGTAGCAGTTGCTAGAGAATCTATGTTTGTGTTTAGTGGACAAAGTGGTGCAAAAATTACAAATAGTCTTTTCCAATTTCATTTTCGAGAGAAACGATGGACTCGTATTTCTACCGAACATATTTTAAGGGCAGCACCGCCACCACCAGCACGACGCTATGGTCATACAATGGTTGCGTTTGATCGTCACCTTTACGTTTTTGGTGGTACAGCAGATTTTACTCTTCCTAATGACCTTCATTGCTATGATTTGGATACTCAAACATGGCACATTATTACTCCATCTTCTGATAGTGAGATACCGTCTAGTCGTTTATTTCATGCAGCAGCAGTGATAGGAGATGCAATGTTCATTTTTGGTGGTACCGTTGATAATAACGTCCGATCTGGTGAAACTTTTCGTTTTCAATTCTCCTCGTATCCCAAATGTACATTGCATGACGATTTTGGGCGTCTTCTGCATTCCCGTCTATTTTGTGATGTCGAATTCATAGTTGGAGAAGATGAAACTAAAATTCCAGCACATATTGCTATGGTTGCCGCTCGTTCAAAATTTTTACGATTACGTATAAAGCAAGCTAAGGAAAAAAGAGAAGAACATTTGGAAGAATTTTGTGACAGTTCTGATTTTTCAATTAAAGACTTACCCATACTTGAGGTCAAACTTATAGATGCAGTACCAGAAGCATTTGATATGGTATTAAATTATATTTATACAGATCGGATTGATCCAACAAAAAAGATTGAAGATCCTTTAAGTAATAGAATAGTTTTACTAATGATGGATGTTTATCGTTTAGCTGTTCAATTTAACATGAAACGTTTAGAACAGCTTTGTGTTCATTATTTAGAGGCTACTATAAATCATTGTAATGTTTTAGAGGCATTACATAATGCTGCTCATCTTAAATTATATTTTATAAAAGAGTTATGTCTAAGTTTTGTTGTAAAAGAGAGTAATTACAATCGAATAGTAATGAGTCAAGAATTTGAATCATTAGATCAGCCCTTGATGGTGGAAATCATCAGACGAAAACAGTTACCACAAACAAAAAATTTCTTGAAATTATTTGATTTAGGAGCAGATATGGGAACAACACTTGAACAAGATATGGAAGCGTTTTTAAAGAGTACAGGACAAGAATTTTGTGATATTACTTTATTACTTGATGGAGTACCAATTCCATCACATAAAGCAGTACTAGCTGCTCGTTGTAGTTATTTTGAAGGATTATTTCGATCATTCATGCCTGAAAGCAATACTGTAAATATACAAATTGGAGAAATGATACCTTCGTCAGAATCTTTTGGTTCACTATTACGTTATATATATTATGCGGATATTTCCATGCCTCCAGAGGATTCCCTGTATTTATTTACAGTTCCAGTTTTTTATGGTTTTACAAATAATCGATTGCAAGCATTTTGCAAACAGAACCTTGAAATGAATGTAACATTTGAAAATGTAATACAAATTCTAGAAGCTGCCGATAGAATGCAAGCAGTAGATATAAAGAAATATGCTTTAAATCTTATTGTGCATCATATTGGAAAGGTGGTGCGTTTACCAAGACTAAAACAATTAAGTCGTGAACTATTATTGGATATAATAGAAGCGATGGCAGATGAACGTAGTGAGGTACAAACTTTTATACATATAAATATTTTTTAA
- Protein Sequence
- MDSIAVTECLTLDFGPFETVHRWQQMPECDEFVGARRSKHTVVAYEDAIYVFGGDNGKRMLNDLLRFDVKEKSWGRALAHGVPPAPRYHHSAVINGSSMFVFGGYTGDIHSNSNLTNKNDLFEYRFKTGQWAEWKFFGKTPVARSAHGAAVYDNKLWIFAGYDGNARLNDMWTISLIPGDSKVWEKVVQSGDCPPTCCNFPVAVARESMFVFSGQSGAKITNSLFQFHFREKRWTRISTEHILRAAPPPPARRYGHTMVAFDRHLYVFGGTADFTLPNDLHCYDLDTQTWHIITPSSDSEIPSSRLFHAAAVIGDAMFIFGGTVDNNVRSGETFRFQFSSYPKCTLHDDFGRLLHSRLFCDVEFIVGEDETKIPAHIAMVAARSKFLRLRIKQAKEKREEHLEEFCDSSDFSIKDLPILEVKLIDAVPEAFDMVLNYIYTDRIDPTKKIEDPLSNRIVLLMMDVYRLAVQFNMKRLEQLCVHYLEATINHCNVLEALHNAAHLKLYFIKELCLSFVVKESNYNRIVMSQEFESLDQPLMVEIIRRKQLPQTKNFLKLFDLGADMGTTLEQDMEAFLKSTGQEFCDITLLLDGVPIPSHKAVLAARCSYFEGLFRSFMPESNTVNIQIGEMIPSSESFGSLLRYIYYADISMPPEDSLYLFTVPVFYGFTNNRLQAFCKQNLEMNVTFENVIQILEAADRMQAVDIKKYALNLIVHHIGKVVRLPRLKQLSRELLLDIIEAMADERSEVQTFIHINIF
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00087267;
- 90% Identity
- iTF_01110217;
- 80% Identity
- -