Olab002231.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Ormyrus labotus
Gene Symbol
LZTR1
Assembly
GCA_035582975.1
Location
JAWWEO010000001.1:32572202-32575471[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 8e-14 1.6e-11 45.0 0.4 3 108 358 492 356 494 0.85
2 4 1.4 2.9e+02 2.4 0.1 75 108 491 524 486 526 0.85
3 4 3e-17 6e-15 56.0 0.0 9 96 588 675 581 688 0.86
4 4 1.8 3.6e+02 2.0 0.0 76 101 689 714 684 723 0.79

Sequence Information

Coding Sequence
ATGAATATTGGAATGGACGGAGATAATATTGCTGCAACAGAGTGTTTAACTCTTGATTTTGGGCCTTTTGAGACTGTACATCGATGGCAGCGAATGCCTGAGTGTGATGAATTTGTTGGTGCAAGGCGCAGCAAACATACAGTGGTTGCTTATAAAGATGCAATATACGTTTTTGGAGGAGATAATGGAAAGCGAATGTTAAATGATTTGCTGCGTTTtgatgtaaaagaaaaatcatggGGAAGAGCTTTTGTTACGGGAAGCCCACCAGCACCCAGATATCATCATTCTGCTGTTGTCAATGGCTCTTCAATGTTTGTATTCGGAGGGTACACAGGTGATATTCACTCCAATTCTAATTTAACTaacaaaaatgatttgtttgaatacaaatttcaaactgGACAATGGACTGAATGGAAGTTTATGGGAaaTACTCCAGTGGCAAGGTCTGCACATGGAGCTGCAGTATACGACAACAAATTATGGATATTTGCTGGATATGATGGTAATGCTCGATTAAATGATATGTGGACAATATCTTTATTgccTGGAGATCAAAAAGTTTGGGAACAAGTTGTGCAATCTGGGGATTGTCCACCTACTTGTTGCAATTTTCCTGTAGCTGTAGCTAGAGAATCAATGTTTGTATTCAGCGGACAAAGTGGTGCTAAAATTACTAACAGTCTTTTCCAATTtcattttcgagaaaaaagaTGGACCCGTATATCCACAGAACACATCTTACGAGGAGCACCTCCACCACCTGCTCGTCGTTATGGTCACACGATGGTCAGTTTTGATCGACACCTATATGTTTTTGGTGGCACTGCAGATTCCACTTTACCTAATGATCTACACTGTTATGATCTTGATACTCAAACTTGGCACATTGTAACTCCATCTTCAGACAGTGAGATCCCTTCAGGACGACTTTTCCATGCAGCAGCAGTAATTGGCGACGCAATGTTTATCTTTGGCGGAACAGTTGACAATAACGTGAGATCTGGTGAAACCTTCcgctttcaattttcttcataTCCAAAATGTACTCTACATGACGACTTCGGTCGTCTTTTAAACGCACGACTTTTCTGTGATGTTGAATTTATTGTTGGTGAAGCTGAAACAAAGATTCCAGCACACATCGCCATGGTAGCTGCACGTTCCAAATTTCTCAGACAGAAAATTAGACAAGCTAAGGAGAAAAGAGCAGAACACTTAGAGGAAATTTATGGCACCTCtgatataaatgtaaaaaatttgccgATGCTTGAGgttaaattaaaagatgctGTTCCAGAGGCTTTTGAAAtggttttaaattacatttatacgGATCGCATTGATCcaacaaagaaaattgaagatCCTTTGAGCAATGGAATAGTTTTACTTATGATGGATGTATATCGTTTGGCTGTGCAATTCAATATGAAGCGCTTAGAACAACTTTGTGTTCACTACTTAGAGGCTACAATAAATCATGCTAATGTTTTAGAAGCATTACACAATGCTGctcatttgaaattatattttataaaagaattatgttTAAGTTTTGTTGTAAAAGATAGCAATTATAATCAAATAGTTATGAGTCAAGAGTTTGAGTCATTAGATCAACCTTTGATGGTTGAGGTGATTAGACGAAAACAGATGCCACAAACGAAACACTTTTTGAAACAGTATGATTTAGTAACAGATATGGgaacaaCACTTGAAGAAGACATGGAAGCATTTTTGAAAGGTATTGGACAAGAATTTTGTGATATTACTCTACTTCTTGATGGTGTGCCAATTCCTTCGCACAAAGCAGTGCTAGCTGCACGTTGTAGTTATTTTGAAGGATTATTTAGATCCTTTATGCCTGAAAGCAATACTGTGAATatacaAATTGGAGAAATGATACCATCATCAGAATCCTTTGGTTCTTTATTGCGGTATATATATTATGCAGATGTATCCATGCCTCCAGAAGATTCCCTTTACCTCTTTACAGTGCCAGTTTTTTATGGATTTACAAATAATCGTTTACAAgctttttgtaaacaaaatctTGAAATGAATGTAACGTTTGAAAATGTTATACAGATATTGGAAGCAGCTGATAGAATGCAAGctgtagatataaaaaaatatgctttgaATCTTATAGTGCACCATATCGgaaaggtgGTAAAACTACCAAGGTTAAAGCAATTAAATCGTGAACTTTTATTAGACATTATAGAAGCTATGGCAGATGAACGAAGCGAGGCTCGAACTTGTCAAGATATGTCAAATGATTGCTGA
Protein Sequence
MNIGMDGDNIAATECLTLDFGPFETVHRWQRMPECDEFVGARRSKHTVVAYKDAIYVFGGDNGKRMLNDLLRFDVKEKSWGRAFVTGSPPAPRYHHSAVVNGSSMFVFGGYTGDIHSNSNLTNKNDLFEYKFQTGQWTEWKFMGNTPVARSAHGAAVYDNKLWIFAGYDGNARLNDMWTISLLPGDQKVWEQVVQSGDCPPTCCNFPVAVARESMFVFSGQSGAKITNSLFQFHFREKRWTRISTEHILRGAPPPPARRYGHTMVSFDRHLYVFGGTADSTLPNDLHCYDLDTQTWHIVTPSSDSEIPSGRLFHAAAVIGDAMFIFGGTVDNNVRSGETFRFQFSSYPKCTLHDDFGRLLNARLFCDVEFIVGEAETKIPAHIAMVAARSKFLRQKIRQAKEKRAEHLEEIYGTSDINVKNLPMLEVKLKDAVPEAFEMVLNYIYTDRIDPTKKIEDPLSNGIVLLMMDVYRLAVQFNMKRLEQLCVHYLEATINHANVLEALHNAAHLKLYFIKELCLSFVVKDSNYNQIVMSQEFESLDQPLMVEVIRRKQMPQTKHFLKQYDLVTDMGTTLEEDMEAFLKGIGQEFCDITLLLDGVPIPSHKAVLAARCSYFEGLFRSFMPESNTVNIQIGEMIPSSESFGSLLRYIYYADVSMPPEDSLYLFTVPVFYGFTNNRLQAFCKQNLEMNVTFENVIQILEAADRMQAVDIKKYALNLIVHHIGKVVKLPRLKQLNRELLLDIIEAMADERSEARTCQDMSNDC