Basic Information

Insect: Subacronicta megacephala
Gene Symbol: IKZF1
Assembly: GCA_958496365.1
Location: OY292515.1:11898210-11905686[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 21 3.7 2.8e+02 2.9 0.9 1 23 54 77 54 77 0.94

2 21 0.032 2.5 9.4 4.1 1 23 84 107 84 107 0.97

3 21 5.8 4.5e+02 2.3 4.0 1 23 189 211 189 211 0.96

4 21 0.002 0.15 13.2 1.0 2 23 217 238 216 238 0.97

5 21 2.4 1.9e+02 3.5 1.4 1 23 244 266 244 267 0.94

6 21 0.24 19 6.7 3.4 2 22 540 560 539 560 0.95

7 21 0.1 7.8 7.9 2.6 1 23 657 679 657 679 0.95

8 21 0.69 54 5.2 0.3 2 23 815 836 814 836 0.96

9 21 0.0061 0.47 11.7 0.6 2 23 917 938 916 938 0.96

10 21 0.15 12 7.3 0.3 1 23 946 968 946 968 0.97

11 21 5.8 4.5e+02 2.3 2.6 1 23 1004 1026 1004 1026 0.93

12 21 0.00028 0.022 15.9 4.0 1 23 1034 1056 1034 1056 0.99

13 21 7.5 5.8e+02 1.9 5.0 1 23 1137 1159 1137 1159 0.97

14 21 0.52 41 5.6 0.4 1 19 1215 1233 1215 1237 0.91

15 21 3 2.4e+02 3.2 0.0 2 23 1245 1266 1245 1266 0.96

16 21 0.15 11 7.3 1.9 1 23 1333 1355 1333 1355 0.94

17 21 0.0068 0.53 11.5 0.9 1 23 1361 1383 1361 1383 0.95

18 21 0.0078 0.61 11.3 2.6 1 23 1473 1495 1473 1495 0.97

19 21 0.0002 0.015 16.4 1.4 1 23 1501 1523 1501 1523 0.99

20 21 0.97 75 4.7 2.7 1 23 1614 1636 1614 1636 0.96

21 21 0.018 1.4 10.2 3.5 2 23 1649 1670 1648 1670 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	21	3.7	2.8e+02	2.9	0.9	1	23	54	77	54	77	0.94
2	21	0.032	2.5	9.4	4.1	1	23	84	107	84	107	0.97
3	21	5.8	4.5e+02	2.3	4.0	1	23	189	211	189	211	0.96
4	21	0.002	0.15	13.2	1.0	2	23	217	238	216	238	0.97
5	21	2.4	1.9e+02	3.5	1.4	1	23	244	266	244	267	0.94
6	21	0.24	19	6.7	3.4	2	22	540	560	539	560	0.95
7	21	0.1	7.8	7.9	2.6	1	23	657	679	657	679	0.95
8	21	0.69	54	5.2	0.3	2	23	815	836	814	836	0.96
9	21	0.0061	0.47	11.7	0.6	2	23	917	938	916	938	0.96
10	21	0.15	12	7.3	0.3	1	23	946	968	946	968	0.97
11	21	5.8	4.5e+02	2.3	2.6	1	23	1004	1026	1004	1026	0.93
12	21	0.00028	0.022	15.9	4.0	1	23	1034	1056	1034	1056	0.99
13	21	7.5	5.8e+02	1.9	5.0	1	23	1137	1159	1137	1159	0.97
14	21	0.52	41	5.6	0.4	1	19	1215	1233	1215	1237	0.91
15	21	3	2.4e+02	3.2	0.0	2	23	1245	1266	1245	1266	0.96
16	21	0.15	11	7.3	1.9	1	23	1333	1355	1333	1355	0.94
17	21	0.0068	0.53	11.5	0.9	1	23	1361	1383	1361	1383	0.95
18	21	0.0078	0.61	11.3	2.6	1	23	1473	1495	1473	1495	0.97
19	21	0.0002	0.015	16.4	1.4	1	23	1501	1523	1501	1523	0.99
20	21	0.97	75	4.7	2.7	1	23	1614	1636	1614	1636	0.96
21	21	0.018	1.4	10.2	3.5	2	23	1649	1670	1648	1670	0.97

Sequence Information

Coding Sequence: ATGCTACAGCAGATGTCCTCGCCGCCGAGCGCACAAGCCGGCGAGGTCGCCACTATCGTGCGCCACCTTGAAGGCCGTGTCTGCGGCGACGTCTCTTCGGAGGCTTCCTCAGATGCCGCGGAAGATTCCGAACTACCACAGTGCAAGATAAGAAGGAATTATAATTGCACCAAGTGCACGTTTTATACGCAGAACCCGCGCGCTTATCTCGTCCACACGCGTGACGCTCACTTTGTTAAACTTAAGATTTACGATTGTCCACACTGTGTTTACGCTTCGAGACATCATCAAAAACTGATAAGACATATCAAAATGGTTCACGCAGAATCGAAGCAGTCACCGGCGACTGGAAAGCTGGATACTGAGTTATCTCCACCCGCTAACGACAATGTAGAGCAAGCAGAGCGTATCGAAGACTTATTGGAGGAAGTCGAGGACTGCGAAGATATGATGATGGAAGTGGACGATGACTCCTTTGAACGTCCCGATGATATTGACGTTGATTGTGAAAGGGTGGCAGACCAACCAGCGCCCTCTGAAGTATTAAAAAGTAAGGGCAAGTTCTTCTCATGCGATAAGTGCAACTACGTAACCCACATAAGAGCTAGATTCACAAAGCACGTCAAGTACCATTCGATGCCAATGATCAAGTGTACAATGTGTGATTTCCGAACACCCTACAAATGGAATCTGGATCGTCACATGAAAAACCACGGTGGAACTGGAAGTTTCAATTGTTCGATGTGCAACTTTACGGCGGATATCAAGCAGAGTCTGACGGTGCACGAAATGAATCATCACACACCGTCAACGGGCCATTCGCTGTCGACTCGCCGCCGCAACCGGGTGGGCGCCAGCGACACGGTTATAGCGGAGTTCGACGCAGCGAGCGCGGTGCTCCCCAAGGAGGAAGAAGGGAGCGGCGACTCGCGGTCCTCACACTCGTTCTCGGTGAGTCGCCGTCGTATATGTGTGTTGTGTGCGTGGCTAGGGGCCGCGCCCCGGCCGCTGCCGCCACCGCCGCCGGTAGCAccgGACATGGGTCTACAATACGCAGAAAGGGAAATAGTCAGTTGCAAAAGTGATTCAAATGATGCTTCTGCTTCTGACGCAATCACAAAAAAAGATGCTTCTCACCTGTCACAGGATGGATACAATCAGCTCTCGCCGAACCATAGTGCAGATGAAAAGTCACAAAGACAAAACAGAAAAATTCCCAGACCAATACCACAACTCATACCGTTGAATGCGTCGACTCCAAACCAAAAACCAACATGTCCTGGTGAACCGCCTCACAAAAAATTTAAGGAATCTGAACCAAACGAAATAGATGATTCCAATTCAGGAAGTAAAACTGAAGACTTCTCTAATGACATTACTCTATTTCCAGTAAATTCGTCAATAAAAGAGACTGCAAGCCGTAAGAAAAACGAATCGTTTTTCGACAGATTGAAAGAAAGGTTATTAACAGAAACAGGTGAAGAAGGATCTCTTAAATGCAAAAATTGTGGATTTGAAAGCAAATGTTTATCAGAACATTCTGTGCATGAGAAAAATTGTTTACCACAAACTAGCCGGATCAATTCAAACTCGACACTTACAAGTTTAAGTTCAACTCGATGTCAAAATTGTAGGCATCGATGTAAATCTAGTGCCGACTTGTACATCCACATGCAAACTTGTGGAAAAAATCAAAAGACGGAAGGCGAAAGTACTATCAAAAGTCAAGATAGTAATGATGCAATCATTCCAATCCATGAAAAAGAGACTGAACCACATCCAATGGAAAACGTCGTGTTCGTTTGGAACAATATTGGTCATGACACTAACAAGTTTGATATACCTCTCGACATCAATATAAATGATGATAGCACTCTACCAGAAATACATAGAAGCTTCGATGCTGAGGTTGTCGATGAGAACGAAACTATGAATTTGTCGCCGAGTCAAGCTGTAGGACGGAAGGTATTCAAGTGTCCACATTGTCCATTTTTCTCCACTACAGCATCCAGATTTCACGTCCATATTGTTGGTCATTTAAACAAGAAACCATTTGAGTGTTCTCTCtgtaaatataaatctaattgGAGATGGGATATAACCAAacatataaaattgaaatcCGCGAGAGATCCAGAGCATAACGATGCGAAAGTATTAATGACTGATGAAACAGGACGAAGAAACTAtagcaaatataataaattcttaGCAATGccagttttaaatgaaaatggtGAAAACGAGTTTCATTATCTGGATGCTACCACATCAGCCGATGGGTCGATGGAAATAGATGAATCGTTAAATGATGCATCAGACGTTATGGATATACAATTTGAAATGCAACCGCTTAACTTACAGACTCAACAAAGTGAAGATAAATACGACTTTACTGATAACAGACTACATGATTTGAAAAAACCTAAGAGGACATTATGGAAATGCAAAAAATGTAATTACAAAGATCCCTCAAAAGAAGCTCTTCTGGAACATGTTCGCGAACACTCCAGATCGGATGGCATCCATGACGAAACAAGCAAACATCCTATGAACAagaaaactgaaaataatactCCCGATCCGGCAGACCTGGCTTATCGTTGCGGTCATTGTAATCAACTATCAAATTGGAAACATGTCATCCAGCGTCATTGCCGATTGAAACATGACGGAGTTATTAAAGTCATAACTACAGTTAAACCAAAACCAGACCCACCAATGAACATTAATGAGATCAACATTGATACCTGCAATAAGTGCCCGTTCCGATCAAGTGACAAAAAACTACTCATCGCCCATTTGCAACAACATCAACCTTCGCCGAATTCAATCTTTAAGTGCTACTTCTGCCCTTTTTTCGTGAAGGATGAACCAGAATTAATTCAACATCTTCTCCTTCACGGTATCACTGACCCAGAAGATTACATAGCAAAAGCAATGGGAACGAAATCCCCGGCACCAGAACACCACGCAcctacttcttcttctttacaCTCCACTAAGCGGCACAAATGTATAGAGTGCCCATACGAAACCAACAGCAAGTCACAGTTCATGTATCACGAACAATTCCATCGACTCCCGGCTGACACCCCTTATAAATGCCCAGAATGTAACTACAGCGTATCTAAAAGGCACTTGCTCCATCAACATCTGCGAGTTCACGGAATTGCTAATAAAAGAGTTGAAAGCGAGGCTGAATTAGAAGCATCGATATCGGCTCAAAATAAGTCGGACGTTAAATTAGAATTAGATGAAATACCGTACGTTTGGGTGTCTGCAAAGAACGAATTTCATAAAATGTACAAGTGCCGGTACTGTTCATATGTAAACTCCCATAAATGTAAAATTCCCAATCATGAAAAAATACATTGTATCGTATTTGAAAACAATGACACAACAATTTACAAGTGCTTGGAATGCAAATTTACGTGTGACAGCGCCTGCCGACTAGCAGAACATTCTAAATCGCATGGTGAAATATATGGTCGCATTTATTGTCCGGTTGAAGATGATGTGCCTGATGAAGAACAGATTACCAAATTACGAAAAGTAATAGAAATTGAAAAATCAACTAATTCGGAAGGTTTTCCTAGAGATGAAAGCTCAGCAAACGAAAGtagagaaataaaattattatatttctgccAAAAGTGTCCAGCAAGattttttgatgatgatgaattagaAGTTCACGACAAATTGCATGATGTAACAACACATGCAAATACATGTAAAAGTTGTGAATTTTCAGTCCCCGAGGAGGACGATTTGGCAGCACATGTTACCGTACATACTGATGAATATCATACCAAAACAAAAATGCTTAAGTTTATTCACAACTCACATCCTTCTCACAGACAACCCGTGCTAGAACTAGTGCACTGTCCAAATACTTCAGAGATTACGTGGATAGCCACAGGTCCAAGCAAAGTTGAAAATATTGAAACTTCTATGAAAAAGACGAATGATACAAAAAACGTGCCAAAACAATATCATTGCAAACTATGTCCTGCAAAGTTCTTCAAAACTTCGGCGCTGACTTACCATTTGGGCTTACATGGAGGCGAAGGCGAACATAAGTGTAAGAAATGTAACTACgccgtaaaaaatattggaaatttAGCCAAACATGAAATATTACACGAAAATGAGAACAAGACTACAAATTGTGATTATGAATCTGGTGAAGATATGGATTACAAAAATATCCCATTGTCGGGTACAGATCTGTTCCAGAGAAAGACTGAGGCTCAAAAAAGAGTCTTAACTGATAAAGATAAGTTAGTTAAGCCAAACGATCATTTTCCGCCTGTTCTACAGGCCGATCCGCAGTTCGGTTATTTGATGCATGGTAATCCCGAATTTATATATCCAACGTACCTCAAAAATGGACGTCAAAAAGAAAAGCGATATAAATGCCACAAGTGCCCCTCAGCCTTTGAAAAACGAGAACAATATAAGATTCATTTATCATTGCATGGTTCCAAACAGAGATATAAATGTGAACTATGTGACTATTCAGTAAAATATTACGCTAATTATGTTCAGCATATGAGGAAACATCAAATGAACGATGAAGCTCAagcagaaagaaagaaaggtacCAACGATTTTATAGAATCTGAAAATCAAAAAGACGTTAAACAAGACGACAGTAGTGATAATATTAAACTTGCAATAAAAACCATGCCAAAGGGGGCTCCTAGAAGCGACTTTCAACAGTTCTCCATAAGTGACCAGCAAACCTTGAGACTACTGCAACGACGGCGTTCAATGAATAATTCTAGCAAGGACGCATCGTCTGAAGTTTCGCCTACGAAAGAACGAAAAATGCACATGTGTTTACTATGTCCCTACACAAATCAACGTCAAGATTCTTTAAGTAATCATTATCGAAGGCATGGTGACATCGATGTTCTTAACGCAGGAAGTCATAAGTCATGTTCTCACTGCGACCTTGTAGTCGTGCAGTCACATTTCCTGCGAGAGCACCTAAAGACCCACTTCAACTACCACAAAACTCTTATTCCCGAATGTTTCGTGGCTAACAAAGATGTCAGATTTACTATAACTAAACTGGATGAAGACAGTGAGCCAGTTGATCTCAAATTAGATGTGCAAAACAAGAAATTTGCATGTAATGATGAAAAGATATTTGTGAAAATTAAAACAGGAGAGCTATTGGTAGAATAA
Protein Sequence: MLQQMSSPPSAQAGEVATIVRHLEGRVCGDVSSEASSDAAEDSELPQCKIRRNYNCTKCTFYTQNPRAYLVHTRDAHFVKLKIYDCPHCVYASRHHQKLIRHIKMVHAESKQSPATGKLDTELSPPANDNVEQAERIEDLLEEVEDCEDMMMEVDDDSFERPDDIDVDCERVADQPAPSEVLKSKGKFFSCDKCNYVTHIRARFTKHVKYHSMPMIKCTMCDFRTPYKWNLDRHMKNHGGTGSFNCSMCNFTADIKQSLTVHEMNHHTPSTGHSLSTRRRNRVGASDTVIAEFDAASAVLPKEEEGSGDSRSSHSFSVSRRRICVLCAWLGAAPRPLPPPPPVAPDMGLQYAEREIVSCKSDSNDASASDAITKKDASHLSQDGYNQLSPNHSADEKSQRQNRKIPRPIPQLIPLNASTPNQKPTCPGEPPHKKFKESEPNEIDDSNSGSKTEDFSNDITLFPVNSSIKETASRKKNESFFDRLKERLLTETGEEGSLKCKNCGFESKCLSEHSVHEKNCLPQTSRINSNSTLTSLSSTRCQNCRHRCKSSADLYIHMQTCGKNQKTEGESTIKSQDSNDAIIPIHEKETEPHPMENVVFVWNNIGHDTNKFDIPLDININDDSTLPEIHRSFDAEVVDENETMNLSPSQAVGRKVFKCPHCPFFSTTASRFHVHIVGHLNKKPFECSLCKYKSNWRWDITKHIKLKSARDPEHNDAKVLMTDETGRRNYSKYNKFLAMPVLNENGENEFHYLDATTSADGSMEIDESLNDASDVMDIQFEMQPLNLQTQQSEDKYDFTDNRLHDLKKPKRTLWKCKKCNYKDPSKEALLEHVREHSRSDGIHDETSKHPMNKKTENNTPDPADLAYRCGHCNQLSNWKHVIQRHCRLKHDGVIKVITTVKPKPDPPMNINEINIDTCNKCPFRSSDKKLLIAHLQQHQPSPNSIFKCYFCPFFVKDEPELIQHLLLHGITDPEDYIAKAMGTKSPAPEHHAPTSSSLHSTKRHKCIECPYETNSKSQFMYHEQFHRLPADTPYKCPECNYSVSKRHLLHQHLRVHGIANKRVESEAELEASISAQNKSDVKLELDEIPYVWVSAKNEFHKMYKCRYCSYVNSHKCKIPNHEKIHCIVFENNDTTIYKCLECKFTCDSACRLAEHSKSHGEIYGRIYCPVEDDVPDEEQITKLRKVIEIEKSTNSEGFPRDESSANESREIKLLYFCQKCPARFFDDDELEVHDKLHDVTTHANTCKSCEFSVPEEDDLAAHVTVHTDEYHTKTKMLKFIHNSHPSHRQPVLELVHCPNTSEITWIATGPSKVENIETSMKKTNDTKNVPKQYHCKLCPAKFFKTSALTYHLGLHGGEGEHKCKKCNYAVKNIGNLAKHEILHENENKTTNCDYESGEDMDYKNIPLSGTDLFQRKTEAQKRVLTDKDKLVKPNDHFPPVLQADPQFGYLMHGNPEFIYPTYLKNGRQKEKRYKCHKCPSAFEKREQYKIHLSLHGSKQRYKCELCDYSVKYYANYVQHMRKHQMNDEAQAERKKGTNDFIESENQKDVKQDDSSDNIKLAIKTMPKGAPRSDFQQFSISDQQTLRLLQRRRSMNNSSKDASSEVSPTKERKMHMCLLCPYTNQRQDSLSNHYRRHGDIDVLNAGSHKSCSHCDLVVVQSHFLREHLKTHFNYHKTLIPECFVANKDVRFTITKLDEDSEPVDLKLDVQNKKFACNDEKIFVKIKTGELLVE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01231174;
90% Identity: iTF_00017790;
80% Identity: -