Basic Information

Insect: Subacronicta megacephala
Gene Symbol: Zfa_1
Assembly: GCA_958496365.1
Location: OY292517.1:5064827-5073361[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 23 0.0055 0.43 11.8 1.0 3 23 646 667 645 667 0.96

2 23 0.24 19 6.7 0.3 1 22 1054 1075 1054 1075 0.95

3 23 8.6 6.7e+02 1.8 0.4 1 22 1117 1138 1117 1140 0.82

4 23 0.0025 0.19 12.9 1.7 3 22 1151 1170 1149 1170 0.94

5 23 3.5 2.7e+02 3.0 0.1 3 23 1179 1200 1177 1200 0.88

6 23 0.02 1.6 10.0 0.2 3 23 1221 1242 1219 1242 0.96

7 23 0.0043 0.33 12.2 3.5 1 23 1248 1271 1248 1271 0.95

8 23 0.14 11 7.4 0.0 1 23 1297 1320 1297 1320 0.90

9 23 0.022 1.7 9.9 3.4 1 23 1325 1347 1325 1347 0.97

10 23 0.0099 0.77 11.0 0.2 1 23 1353 1376 1353 1376 0.95

11 23 0.0027 0.21 12.8 1.3 1 23 1389 1411 1389 1411 0.97

12 23 0.0002 0.016 16.3 1.8 1 23 1462 1485 1462 1485 0.97

13 23 0.002 0.16 13.2 1.3 1 23 1545 1568 1545 1568 0.96

14 23 0.0028 0.21 12.8 2.1 2 23 1594 1616 1593 1616 0.95

15 23 0.13 10 7.5 0.1 2 23 1622 1644 1621 1644 0.93

16 23 0.011 0.88 10.8 0.2 1 21 1687 1707 1687 1708 0.95

17 23 0.00048 0.037 15.1 1.0 1 23 1718 1740 1718 1740 0.93

18 23 0.00013 0.01 16.9 0.3 2 23 1833 1855 1833 1855 0.93

19 23 4.5e-07 3.5e-05 24.7 1.4 3 23 1862 1882 1861 1882 0.98

20 23 0.046 3.5 8.9 0.4 1 23 1901 1923 1901 1924 0.95

21 23 0.21 16 6.8 0.0 1 23 1946 1968 1946 1968 0.97

22 23 0.032 2.4 9.4 0.6 1 23 1974 1997 1974 1997 0.95

23 23 0.00029 0.023 15.8 0.4 1 23 2005 2028 2005 2028 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	23	0.0055	0.43	11.8	1.0	3	23	646	667	645	667	0.96
2	23	0.24	19	6.7	0.3	1	22	1054	1075	1054	1075	0.95
3	23	8.6	6.7e+02	1.8	0.4	1	22	1117	1138	1117	1140	0.82
4	23	0.0025	0.19	12.9	1.7	3	22	1151	1170	1149	1170	0.94
5	23	3.5	2.7e+02	3.0	0.1	3	23	1179	1200	1177	1200	0.88
6	23	0.02	1.6	10.0	0.2	3	23	1221	1242	1219	1242	0.96
7	23	0.0043	0.33	12.2	3.5	1	23	1248	1271	1248	1271	0.95
8	23	0.14	11	7.4	0.0	1	23	1297	1320	1297	1320	0.90
9	23	0.022	1.7	9.9	3.4	1	23	1325	1347	1325	1347	0.97
10	23	0.0099	0.77	11.0	0.2	1	23	1353	1376	1353	1376	0.95
11	23	0.0027	0.21	12.8	1.3	1	23	1389	1411	1389	1411	0.97
12	23	0.0002	0.016	16.3	1.8	1	23	1462	1485	1462	1485	0.97
13	23	0.002	0.16	13.2	1.3	1	23	1545	1568	1545	1568	0.96
14	23	0.0028	0.21	12.8	2.1	2	23	1594	1616	1593	1616	0.95
15	23	0.13	10	7.5	0.1	2	23	1622	1644	1621	1644	0.93
16	23	0.011	0.88	10.8	0.2	1	21	1687	1707	1687	1708	0.95
17	23	0.00048	0.037	15.1	1.0	1	23	1718	1740	1718	1740	0.93
18	23	0.00013	0.01	16.9	0.3	2	23	1833	1855	1833	1855	0.93
19	23	4.5e-07	3.5e-05	24.7	1.4	3	23	1862	1882	1861	1882	0.98
20	23	0.046	3.5	8.9	0.4	1	23	1901	1923	1901	1924	0.95
21	23	0.21	16	6.8	0.0	1	23	1946	1968	1946	1968	0.97
22	23	0.032	2.4	9.4	0.6	1	23	1974	1997	1974	1997	0.95
23	23	0.00029	0.023	15.8	0.4	1	23	2005	2028	2005	2028	0.96

Sequence Information

Coding Sequence: ATGAATGTGAACTATGATCGTGTTTGTAGACTGTGCTTGTCATCTCGAGGCGAATTACTGCCGATTTTTCCTACCACCAGTTCGGATGACTCGGAACCTCCCGTCCTCGCTTCGAAAATCAAGGATTGTGTCTCCGTACAGATAAACGAAAATGACGACCTGCCTACTAATGTCTGCAGGAAATGCATGGACAATGTCAATAACTggcatatatttaaaaatatttgtgaaaggACACAAAACAAACTACAGTCTCTGAAAGATGGCAGCCAACTAGAAGAGgtaaaaataaaaagtgaaccATTATCTGATGAGGCTTATGATGATGGAGTGGTCATTGATGGCTCATATCCTGTCATTGAGAATGCTGGCTTGTCAGCTAAACTGCAGCCTGAAGGTCCTCCGATCTTGGCATCATTGGGGCTCACACCACGGAGTGATAAGAAATGTGTGGATCCTCGAATGGATTGGCATCGGGTCCATGCAATTTTGGACATGGTTCAAGATAATGAGGTAATTGATTCTCTACAAACAAAGGAAGAGTGTGATGTTTTGCAACATTCTGACCATGACTCTGACACAGAGTCTGAGCTCCAACCAGAAATTGACGATGATTATATTGATTGCAAATTCGGATAcatatgcaaaaataaaaaagttatttcgaAAGTCCCAAAACTATCGACTGCAGTAAATAATGCTAGAATCAAAGAATCATTCAAACTTAGAAAACGTAAATCCgatttttgtaaacattttttacgACCTAAAAATGCATGGCAATTGTTGTTCACTGATGACCTACTAGAATTGATTGTTGCTTCTACTAATGAAAATATCGTCGCAAACGGGAAAGATTTCTCAGAGACTGCTAGCGTCAGCGAAATTAAAACGCTTATCGGTATTCTGTATATGCACGGCATAATGCGGTCGACGCATCAGAAATGTATTGACCTTTGGAATAGTGAATGTGGCATACCTTGCATTAGAAATGCCATGACGTATGAAAGGTTCAAACTCTTGCTTCAAAACCTCAGCTTCGATAAAGTGGACGACGATAGTATTATTCAGTTCGACATAATGAAGCGTATGCGTAAAGTATTCGAAATCTTCGCCATGAATTGCAGAACATCACATGAGATCGAGAATATTGCAGTTATTGATGAGATCATTGTGCCAGTTTATGGACCTTGCCCATTTCGATACAATATTGATAAGAAACAATTGAAGCGGGGCATAAAAATGGTATTGCTTGTTGATTCATCTACATTCTACATCAGTAATTTAGATGTCATAACTGATCCTTACTTTGGCGCCGAAGAGATGACGAAGAAGTTGGTTCAGCATTTAGCTGGAACTGGCAGGTCGATTGTAATGGACAGTTGGTTTACATCTACTTCATTAATAGAAAGTCTTAAAAATGAGTACCAGTTGTTTTCAATTGGAGCATTAAATCCAAACAGCGATTTGATCCCGCCGTTATTTCTTTCGCATTATAGGAAATGCCGAACATTCATGTCAGGATTTTTTGATCACGAAGTATCACTTACTTCTTATGTTAATACTGAAGGGAAATCAGTGAATGTGTTGACTAATGAGCCGAGGTATTACAGGAAAGGACATATAAATCACACTACAGTTGTATCAGTGTATAAGAAGAATCAGTCTGCTGTAGAAGTTGTTGATGTTCTCATGAATTACTACACAACAATGCAACACACTAATGATTGGACTTTGTCGTTATTCTTTACGTTGCTCAACATTGCTTCGGGAGGAGAGAGTGAAAACAATGAAGAGGACGAGGAAGAAATGAATGAGGCCTCACAAACATTCCCGAAGATGCCCCACATGCCGGAGGTGTCCATTACAGTCATGAGGCCTACGGGTGAAACTCTGCATGCTCGCCAAGGCATTCATCAACTCGCCTCCAAAGACTGTCTCGTCTGCGGACGATCCTACAGGTACTCACATAACGCCCGCCGACATGAGCTTACTGCTCACAGCTTCGACAggtatacaaacaaaataacccCCAACAAGAAAACCCTCACTCACCTTCAACCTAAACTCAGGCCCAACCCGTTTAACCCCAAAGCACGGATGATGCCGAATCCTATTAGCCATAAGATGCAATTCTTGAACAAGAATatctcaacaaaaataatgccCGTTAACAAAGTTATAACACCACAGAAACCTATTCCAATAAAATCGTCAAAGacaacacaaaataatttaccttATCCACTACGTATTAAAGCCCTTaaagatttacaaataaagaagAAGGAGCCACAGATTCTAAAGACTTTGTTGACATCCAAACCTGAAGTTCTGGTATCAGAACCAGAGATACTCAATTCTGGTCCAGAAAGCCCGGAGACTTTGATATCCGAGCCTGAAATCGCGTCTTTTCAAGTCGAAGCTATTCTTACGGAGCCCGATGCTGATGCCTATGATCCACAGCAAGGTGACGAGGAAGCCGACGAAGAAAATCATAATAACCAAAGTCAAAACTATGACACAGTGGATATGGAATCTGATAACGAAATCGAGATTGCTCGTCAGCAAGGTATTGAACACGATGGCGAGGATTATGCTGATGGGGAAGAGAATGTCGACCATTGTGAAGAGGAAAATAATATGGAAGGCCCTCAGAGCGATATTGAAAAAGATGGCAATGACGATACAGTAGAAAGCCAAGAACCCATGGATCAAGAGGATGACAGTGTTGATATAAAACCTGAGGGAGAAACTAAGGACGAGGAGGGCCAAGAGGATAGAGAACCTGAAGAAAATGAGATGAATCATAATGAAAACGCAGAGGAAGACGATGACGACCTCCCGATATCATTGGCGCCAGTCGTCGAAATTAACGAAGGTATACAAGCCAACTCGTTTAACAGTGAAGTCAATGAAGGGCAAGAGGAACTCGACGAAACTGCCGATCCTGATGAAACAGTTGAAGACGAGGAACAGGCGAAGGAACTCGATCCTGACAAAACATACGTTACAAAAACCCAAAGAgactttattcaaaaatatcgcGACGTCATTCAGCAAATTAATACGAAGCGTTGTTTATGTTGCGACCGCGAACATCCCCGCCGGAAAGCTGTCATACAGCATTTACAGAAAAATGGGCACAAAGTCCCAAAACATACGTGctacaattgtgttatcacatTTGGTCACATTGGCGCTCTTCTTAGTCACATGAGGTCAAACTCGTGCACTAATTTGtggaaaattatttacaatgaaaatgGCATTACTGATGATTTAGTTCTAGAAGATGAGCCGAAAGAGGTTAAGGTTCAATATAAGGATATTTTCAATGCTAGGTCTTATGCATGCAAACTGTGCCCAGCGAAGTTCCAATTGAAACAGTTTATTATGAAGCACGTTCTCGATACTCATGAGGATGGCCAGTCCAGGGTACCGCTCGCTTGTGTGCACTGCCGTTCTCGATTCAAAGACAAAAGTCTACTTAAAAAACACATTCGAAAAGGCGAATGTACAGTGTATATTGCTTGCGATTTGTGCACAGAAAAGTTCGGTAATATGCAGACTTTCAACGACCACGCTCTTGCTGTTCACGCTGGTAGTTTCGATCAGTCGGATAATCAGAGCAAATGTGTTGACGGTCGACCAACCGACTGTCCATTGTGTGGCAAGAAAAACAGCAGCTATCCGAATTTAGTGAAACATTTGAAGATTATACACAGCGAGGAGAAACCTCATTACTGCCAGCATTGCGATTCTAAATTCGAACAGGCTACTGATCTAAACAAACACATTTACATGGAGCATTCTGACAGAACATTAGGCATGTCGACTGCCGAACCGGATATGTCAATTGTGAAGGAAGAAGCAGAAGAGTATCATTACTCATGTACGGAATGTAATGCCATATTTGAAACTGTCGACGCGTGGACTGATCACCAAGTAGCCGAACATAACCAAGTTGCTCACCACTGTGACCAGTGTGAGAAGAAGTTCCTTCGTCCTTCCGAACTTGCGGAGCACAAAAATACCCATTTGAGGGTTAAATTCTACCCTTGTAGTGTATGCCCGAACTCGTACAGCACTCCACAGAAATTATCCGAGCATGTGCAACAGTCTCACCCTGGCATTGGTTCAGTTGCGGCAGCCGAGACAGAATTCTTTTGCGACATCTGCATCAGATCGTTCAAAAGTCGCCAAGCTTATTCAAATCATATGCGTATTCACgctaaagtacctactactaacAGAAAACCAggtgaaattattaaaacttcatTTACACCTCAAACTATTGGGAAACCTATCAAACAATATCCTATGGTTCAACCTGGTTTTGTCTCATTTAAGCCTAATTACAATATCCCTAATGCTCCATACTCGTGTGACATTTGTGGCAAAGGATTCATGCACAAGAAGAATATTTGGAAACACAAGAAAGTGTTGCATGCTGATATTTTAGTTGATAGACATGATAGTGAAGAGAATACTATGCAAGCTTCCACTGAAGAAGAAGAGTTTAACCCTGATGAAAACGGCGCTGTTCTGTCAACGCCacaatttaatagttttaatttcaCAAACTTCCCAAACAATGTGCAACAAACGCCACAAGAAGCAATGCCTTACTCGTGTGAATTATGTTCCAAACGATTCCCGCTTAGAACTAGTTTGTGGAAACACAAACGCGCTAAACACGGAATTGTTAACCCTAGCTCTAGCGGTAATGAGGTATCCCAGCCATCAGCTAGCGGTGAAGGAAGCAGTAGGTCAAGTTGCACTATATGTCGAATTACGTTTTCAGATAAGAAGTCATACTATCGCCACCGAAAGAATATCCACAAATCAACCGTTCAAATGTGCAAATTATGTGGTAAACCTCTTAGTTCTACCTTGGAGCTCTATGAGCACTTGAAGGCGGCCCACGCACGGGAACTCCTGGGCTATAACGCCAACCAAGGATCCAATAAATCCCAAGATATGACACAAGAAGATCCCGATTACGAAAATGATCAAGAGTCTGCTGACCCAAGCGTCGATTATCAAGCCCGTTACCCGTGTGACACTTGTGGCAAACAATTCGTTGGATTGCTAGCATTGCAAAACCACCAGTGCATCAATCAGTTGCCGTCACAACCACAGACTTTTGACTGTGAAATTTGTCACAAGAGTTACACTTCAATATCAGCATTAAAAAGCCATCGCGGCTGGCATTTGCGGTCGCCCGATGGAAAAGCAGCGGCCAACAATTCTGGACTTTGGATGCCTCAGCACAAAGTTACTAGTAAGATAAGTAAACATGAGGTCATCGACCCCTCTCAGCTTGCGAAGGTCACACATACACCTACTCCCCCTGTTCCTGCTAGCGCTGCCGTAGCGAAAAGAAGACTACCGCCAGAGGTAGAAGTTACAGTTgtaaatccaaataaaaaattgagGTCAGACGATTCCGTGGAGGATCCACAGAATTCTGGTGCAATTGAGGATAGATACTGTACGATTTGTGACAAAGAGTTTACAAAACGAGCAGCATATCAGCGCCATATGGACGAAGTGCATCAGCCAAACTCCGTGTTCTGTCCAGTCTGTGATAAGAGTTTCACTAGGAAGTCCACATTGCTTATCCACATGAAAAAGCATTACGAAAGTGGTGAGGGCAGTTCTTCTGCCACCGGTCAAGGAGATGATGATATGTTCTCTTGTGATTTGTGTGGTGCACAGTATGATAGTGACCAAGCGTTAAGGGCGCACCGAGCAAGGCACCACGGAGAAGATGAGTCGGGAGAAGAGAGTGATGACGGGAATGTTCCTATTGCTCAGCCCGGTGAATTTACATGTGCGCAGTGTGGTGATGGAGTCGCAACGCCCAGAGACCTTATAGCCCACCGCACAATGCACGCTACTCCCACCAAATTCTTCTGTAATATATGCAAAGTGTACTTTGCCCGGGCGCTGGATCTATCCTCACACACTCGGGCACGACACGCCGACAACGAAAAGGTATTCTTTCCGTGTGCCATGTGCGACAGGTTTTATATGAACAAGAAAAGTTTGCAACGGCACATCGAAATGGCGCACTGA
Protein Sequence: MNVNYDRVCRLCLSSRGELLPIFPTTSSDDSEPPVLASKIKDCVSVQINENDDLPTNVCRKCMDNVNNWHIFKNICERTQNKLQSLKDGSQLEEVKIKSEPLSDEAYDDGVVIDGSYPVIENAGLSAKLQPEGPPILASLGLTPRSDKKCVDPRMDWHRVHAILDMVQDNEVIDSLQTKEECDVLQHSDHDSDTESELQPEIDDDYIDCKFGYICKNKKVISKVPKLSTAVNNARIKESFKLRKRKSDFCKHFLRPKNAWQLLFTDDLLELIVASTNENIVANGKDFSETASVSEIKTLIGILYMHGIMRSTHQKCIDLWNSECGIPCIRNAMTYERFKLLLQNLSFDKVDDDSIIQFDIMKRMRKVFEIFAMNCRTSHEIENIAVIDEIIVPVYGPCPFRYNIDKKQLKRGIKMVLLVDSSTFYISNLDVITDPYFGAEEMTKKLVQHLAGTGRSIVMDSWFTSTSLIESLKNEYQLFSIGALNPNSDLIPPLFLSHYRKCRTFMSGFFDHEVSLTSYVNTEGKSVNVLTNEPRYYRKGHINHTTVVSVYKKNQSAVEVVDVLMNYYTTMQHTNDWTLSLFFTLLNIASGGESENNEEDEEEMNEASQTFPKMPHMPEVSITVMRPTGETLHARQGIHQLASKDCLVCGRSYRYSHNARRHELTAHSFDRYTNKITPNKKTLTHLQPKLRPNPFNPKARMMPNPISHKMQFLNKNISTKIMPVNKVITPQKPIPIKSSKTTQNNLPYPLRIKALKDLQIKKKEPQILKTLLTSKPEVLVSEPEILNSGPESPETLISEPEIASFQVEAILTEPDADAYDPQQGDEEADEENHNNQSQNYDTVDMESDNEIEIARQQGIEHDGEDYADGEENVDHCEEENNMEGPQSDIEKDGNDDTVESQEPMDQEDDSVDIKPEGETKDEEGQEDREPEENEMNHNENAEEDDDDLPISLAPVVEINEGIQANSFNSEVNEGQEELDETADPDETVEDEEQAKELDPDKTYVTKTQRDFIQKYRDVIQQINTKRCLCCDREHPRRKAVIQHLQKNGHKVPKHTCYNCVITFGHIGALLSHMRSNSCTNLWKIIYNENGITDDLVLEDEPKEVKVQYKDIFNARSYACKLCPAKFQLKQFIMKHVLDTHEDGQSRVPLACVHCRSRFKDKSLLKKHIRKGECTVYIACDLCTEKFGNMQTFNDHALAVHAGSFDQSDNQSKCVDGRPTDCPLCGKKNSSYPNLVKHLKIIHSEEKPHYCQHCDSKFEQATDLNKHIYMEHSDRTLGMSTAEPDMSIVKEEAEEYHYSCTECNAIFETVDAWTDHQVAEHNQVAHHCDQCEKKFLRPSELAEHKNTHLRVKFYPCSVCPNSYSTPQKLSEHVQQSHPGIGSVAAAETEFFCDICIRSFKSRQAYSNHMRIHAKVPTTNRKPGEIIKTSFTPQTIGKPIKQYPMVQPGFVSFKPNYNIPNAPYSCDICGKGFMHKKNIWKHKKVLHADILVDRHDSEENTMQASTEEEEFNPDENGAVLSTPQFNSFNFTNFPNNVQQTPQEAMPYSCELCSKRFPLRTSLWKHKRAKHGIVNPSSSGNEVSQPSASGEGSSRSSCTICRITFSDKKSYYRHRKNIHKSTVQMCKLCGKPLSSTLELYEHLKAAHARELLGYNANQGSNKSQDMTQEDPDYENDQESADPSVDYQARYPCDTCGKQFVGLLALQNHQCINQLPSQPQTFDCEICHKSYTSISALKSHRGWHLRSPDGKAAANNSGLWMPQHKVTSKISKHEVIDPSQLAKVTHTPTPPVPASAAVAKRRLPPEVEVTVVNPNKKLRSDDSVEDPQNSGAIEDRYCTICDKEFTKRAAYQRHMDEVHQPNSVFCPVCDKSFTRKSTLLIHMKKHYESGEGSSSATGQGDDDMFSCDLCGAQYDSDQALRAHRARHHGEDESGEESDDGNVPIAQPGEFTCAQCGDGVATPRDLIAHRTMHATPTKFFCNICKVYFARALDLSSHTRARHADNEKVFFPCAMCDRFYMNKKSLQRHIEMAH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00017541;
90% Identity: iTF_00758469;
80% Identity: -