Basic Information

Insect: Sphenella marginata
Gene Symbol: Hr39
Assembly: GCA_951509765.1
Location: OX608080.1:92792988-92797594[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.14 2.5e+03 -0.9 2.0 130 184 19 72 4 96 0.77

2 5 0.34 6e+03 -2.2 7.0 57 154 150 253 117 269 0.57

3 5 3 5.3e+04 -6.6 7.9 56 141 340 375 267 462 0.50

4 5 2.1e-20 3.7e-16 61.1 1.9 1 157 552 713 552 724 0.73

5 5 4.3e-80 7.7e-76 257.7 0.4 184 408 705 919 703 919 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.14	2.5e+03	-0.9	2.0	130	184	19	72	4	96	0.77
2	5	0.34	6e+03	-2.2	7.0	57	154	150	253	117	269	0.57
3	5	3	5.3e+04	-6.6	7.9	56	141	340	375	267	462	0.50
4	5	2.1e-20	3.7e-16	61.1	1.9	1	157	552	713	552	724	0.73
5	5	4.3e-80	7.7e-76	257.7	0.4	184	408	705	919	703	919	0.95

Sequence Information

Coding Sequence: ATGTCCTCCACAAAGGCAGAGAGCGCTGTGAGCGCTACAACCACAGCGGTCGCATTTGCCTCCACTTTAACGGGAAGCGCTTTCCAGTTGCCCGTGAATATGCACAGTCACGCACAAATTACAGCGAATGGCACAAGTACAACtacgacaacaacaaccacaacaacgcGCAACAACATATCCGTCACGAATATCAAATGCGAAATGGATGAAAACATTGCGGCAACGCTGCTGCCCAACGGCAATTCAGTGCCAGTTATAGCGACGACAGGCACAGCTGCGAGCTACTATAACGGTACAAGTAGTGGGAGTGGGAGTGGCAGTGTTGGTATACGCATACCAGTCACGAAGGCGGAAGATTCCGATTCAGAGACAGAATTAACAAACATTGAGAATTTGAAGGTGACGCGCCGTGTACACAACAATGTGGATAGCAACAACTCAACGGCTGGTGCGAGTGTGATAAGCgctaacaacaacacaaaccaCAATAAAAATGGACCACGTCCCATGTCCTGGGAGGGTGAACTCTCCGAAACGGAGACGACTGAAACCGAATTCATGGAAACTGAAAATTCATTAAGTAATAGCGGCATGCCAACATCAGCTGCGGCGCATACATTGCATGGAAGTATTGTCAGCAGTATGGGCGTGGCGGTGATCAAGAGCGAGGCCAGCACTACCACAACATCCATGCAACACAATACGCTAGCACCCACACCAACACATGCCATAAAACCCGAACAAATGGAACAAATCTGCGCAGAGCTACAAGGTGGTGCGCCTGCGTCTTTTGGCAATGTAGCGCGCATTGGTTTGGGTAGCAGCAGCAGCGCTGGTAGTCTCTATCCTGCGCCCCATACTAAACTGGCGCCCACGCAAAGCGATCCCATCAATTTGAAATATGAACCGGATGCTTCCGCTGCGCACATTTCTAATGGCGCAAATATGAATTCGCCGCTTTTGACGCGTAACAAATCGGCGACGTTGCCACTACCTGCCAATCCCAGTCCAGATTCTGCCATACATTCCGTCTATACGCACAGTTCGCCGTCCCAATCGCCATTGACGTCACGTCATGCACCATATACGCCATCGCTGAGTCGCAATAATAGCGATGCATCGCATAGTTCATGCTATTCCTACAGCTCAGAGTTTAGTCCAACGCACTCACCTATACAGGGTAGACATGCGCCGCCCGCTTCGGCGCTTTACGGCAGCTTCAATGGTTCGTTACATCATTCGGTGCTCTATCGACCCATTACAGTGGATAGTGGCGGCGGCAGTGGTGCAACGGCAGTCAATGGTAATTCGAGCGCGCAGAATAGCTCAACCGAGGCACAAAATCTTAGCATGGATACAAAAGTGTCACCACTCAATATCGGCTTGGAGGGACTGCCTGCCTCGCCGGCGGGTATTTCACGTCAACAGCTAATTAATTCACCCTGCCCCATTTGTGGTGATAAAATCTCTGGCTTCCATTATGGTATTTTCTCATGCGAATCGTGTAAGGGTTTCTTTAAACGTACCGTCCAGAATCGTAAGAACTATGTTTGTGTGCGCGGGGGGCCATGTCCGGTGAGCATTTCGACGCGTAAGAAATGTCCCGCTTGCCGTTTTGAAAAATGCCTACAGAAGGGGATGAAACTCGAAGCGATACGTGAAGATCGCACACGTGGCGGACGTTCAACATACCAGTGCTCATACACCTTGCCCAACTCAATGTTGAGTCCTTTGATGAGTCCCGAGCAGCAAGGCGCTGCAGCAGCGGCGGCAGTAGCTGCAGCTGTCGCAAatcagcagcaacaacatcaacagGGACGACTAGGCGCACAAATGgcacatgcaacaacaacgcatcAGCATGCCTTAAATGGACTGCCAGCGGGTCTAGGCAGCAGTGGACAAGCCATAATCAAATCGGAACATTGCGATGAGGGTAGTGCTTCGGGGCGCGCTACAAACATTCCCTTGCTATTGCAGGAAATCATGGATGTCGAGCATCTGTGGCAATATAATGAAGCTGAATTGGCGCGTCTCAATCAACCGATCTCCACATCGTCTTCTTCCACCTCCTCCTCGAATGGTTCCGCGTCTTCATCGTCGTCCAATCCACAAATGACGAACCCCTTGCTGGCGAGTGCTGGTTTCGGCAATGGCGAAAATACAAATCCCGATCTGATAGCGCATCTGTGCAATGTGGCCGATCATCGGCTCTACAAGATCGTGAAGTGGTGCAAGAGTTTGCCGCTCTTCAAGCATATTTCGATCGATGATCAAATTTGTTTGCTGATCAATTCATGGTGTGAACTTTTACTTTTCTCCTGTTGTTATCGTTCGATCGATACGCCCGGCGAGATAAAGATGTCACAAGGCAAGAAGATTAGTTTGGCGCAGGCCAAATCAAGCGGTTTGCAGGCTTGCATCGAACGCATGCTCAACATGACCGAAAACTTGAGACGATTACGCGTCGATCGCTATGAATATGTTGCCATGAAAGTTATTGTGCTGTTGCAGTCAGACACCAGCGAACTGCATGAGCCAGTCAAAGTGCGTGAATGTCAGGAGAAGGCTTTACAAGCTTTGCAAGCCTACACGCTTGCGCACTATCCAGATACGCCGTCCAAATTTGGTGAACTATTACTACGTATACCCGATTTACAAAAGACATGCCaaCTCGGCAAGGAGATGCTCACAATCAAATCACGCGATGGAGGTGATTTCAATTTACTAATGGAACTTCTGCGTGGCGAGCATTGA
Protein Sequence: MSSTKAESAVSATTTAVAFASTLTGSAFQLPVNMHSHAQITANGTSTTTTTTTTTTRNNISVTNIKCEMDENIAATLLPNGNSVPVIATTGTAASYYNGTSSGSGSGSVGIRIPVTKAEDSDSETELTNIENLKVTRRVHNNVDSNNSTAGASVISANNNTNHNKNGPRPMSWEGELSETETTETEFMETENSLSNSGMPTSAAAHTLHGSIVSSMGVAVIKSEASTTTTSMQHNTLAPTPTHAIKPEQMEQICAELQGGAPASFGNVARIGLGSSSSAGSLYPAPHTKLAPTQSDPINLKYEPDASAAHISNGANMNSPLLTRNKSATLPLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQGRHAPPASALYGSFNGSLHHSVLYRPITVDSGGGSGATAVNGNSSAQNSSTEAQNLSMDTKVSPLNIGLEGLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCPVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLMSPEQQGAAAAAAVAAAVANQQQQHQQGRLGAQMAHATTTHQHALNGLPAGLGSSGQAIIKSEHCDEGSASGRATNIPLLLQEIMDVEHLWQYNEAELARLNQPISTSSSSTSSSNGSASSSSSNPQMTNPLLASAGFGNGENTNPDLIAHLCNVADHRLYKIVKWCKSLPLFKHISIDDQICLLINSWCELLLFSCCYRSIDTPGEIKMSQGKKISLAQAKSSGLQACIERMLNMTENLRRLRVDRYEYVAMKVIVLLQSDTSELHEPVKVRECQEKALQALQAYTLAHYPDTPSKFGELLLRIPDLQKTCQLGKEMLTIKSRDGGDFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00082980;
90% Identity: iTF_01358066; iTF_00992626; iTF_00992707;
80% Identity: iTF_01358066;