Basic Information

Insect: Merzomyia westermanni
Gene Symbol: Hr39
Assembly: GCA_949987695.1
Location: OX465289.1:172814729-172821311[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 2.2 4.2e+04 -4.8 7.6 61 180 160 252 56 268 0.43

2 3 3 5.8e+04 -14.0 15.9 98 144 319 365 197 425 0.48

3 3 7.9e-95 1.5e-90 306.2 7.1 1 408 553 924 553 924 0.83

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	2.2	4.2e+04	-4.8	7.6	61	180	160	252	56	268	0.43
2	3	3	5.8e+04	-14.0	15.9	98	144	319	365	197	425	0.48
3	3	7.9e-95	1.5e-90	306.2	7.1	1	408	553	924	553	924	0.83

Sequence Information

Coding Sequence: ATGTCCTCCACAAAGGCAGAGAGCGCTGTAGGCGCCACACCCACAGCTGTCGCATTTGCGTCCACGTTAACGGGAAGCGCATTTCAGTTGCCCGTGAGTATGCACAGTCACGCACAACTTACAGCTAATGGCAGTAGTAATCACAACGCGAATGGCACAAGTACAACTACGacatcaacaacaacgcgcaacaaCATATCCGTCACGAATATCAAATGCGAAATGGATGAAAACATTGCGGCAACGCTGCTGCCCAATGGCAATTTAGTGCCAGTTATAGCGACGACAGGCACTGCTGCGAGCTATTATAACGGTACAAGTAGTGGGAGTGGCGGTGTGGGTATACGTATACCAGTCACGAAGGAGGAAGATTCGGATTCAGAGACAGAACTAACAAACATTGAGAATTTGAAGGTTACGCGCCGAGTACACAACAATGTTGATAGTAGCTCAACGGATGGTGCGAGTGTGATAAGCGCCAACAACATAAACCACAATAAAAATGGACCACGTCCCATGTCCTGGGAGGGTGAACTCTCCGAAACGGAGACGACTGAAACAGAGTTTATGGAAACCGAAAATTCATTGAGTAATAGTGGCATGCAGACGACAGCTGCGACGAATACTTTGCACGCAAATATTGGCAGCAGTATGGGCGTGACGGTAATCAAGAGCGAGACGTCCACTACAACATCCGGGCAGCACAACACCTTAGCACCCACACCCACACAGGCCATAAAACCCGAACAAATGGAACAAATCTGCGCAGAACTTCAAGGTGGTGCGCCTGCGACTTTTGGCAACGTAGCGCGCGTTGGTTTAGGTAGCAGCAGCAGCGCTGGTAGTCTGTATACTGCGCCACATACTAAACTTGCACCTACGCAAAGCGATCCTATCAATTTGAAATATGAACCGGATGCTTCCGCCGCGCACATTTCCAGTGGCGCGAATGCGAATTCGCCGCTTTTGACACGTAACAAATCTGCAACGTTGCCTCTACCTGCCAATCCCAGTCCAGATTCTGCCATACATTCCGTCTATACGCACAGTTCGCCGTCCCAATCGCCATTGACGTCACGTCATGCGCCATACACGCCATCATTGAGTCGCAATAATAGCGATGCGTCGCATAGTTCATGCTACTCCTACAGCTCAGAGTTCAGTCCAACGCACTCACCCATACAAGGTAGACATGCGCCACCAGCTTCGGCGCTTTACGGCAGCTTCAATGGTTCGTTACATCATTCGGTTCTCTACCGACCCATCACAGTGGATAGTGGTGGTGGCAGTGGTGCAACGGCAGTCAATGGTAATTCCAGCGCGAACAATAGCGCAGGCGAGGCCAAAAACCTTAGCATGGATACAAAAGTGTCACCGCTCAATATTGGACTGGAAGGGCTGCCTGCCTCGCCGGCGGGTATTTCACGTCAGCAACTTATTAATTCGCCCTGCCCCATTTGCGGTGATAAAATTTCTGGCTTCCATTATGGTATTTTCTCATGTGAATCTTGTAAAGGCTTCTTCAAACGTACAGTCCAGAATCGTAAGAATTATGTTTGTGTGCGCGGCGGTCCGTGCCCGGTGAGCATTTCCACGCGTAAGAAATGTCCCGCTTGTCGCTTTGAAAAATGCCTACAGAAGGGTATGAAACTCGAAGCGATACGTGAAGATCGCACACGTGGTGGACGTTCAACATACCAGTGCTCATATACCTTACCCAACTCAATGTTAAGTCCTCTGATGAGTCCAGAGCAACAAGGCGCTGCAGCAGCGGCAGCGGCAGTAGCTGCAGCTGTCGCAAATCAGCAGCAACATCAACAGGGACGGCTAGGCGCGCAAATGGCTCATACAGCAACACCGCGTCAGCAAACCTTAAATGGACTGCCAGCGGGTCTAGGCAGTGGACAAGCCATAATCAAGTCGGAGCATTGCGACGAGGGTAGTGCCTCAGTGCGCGCTACAAACATTCCATTGCTATTGCAGGAAATCATGGATGTCGAGCATCTATGGCAATATAATGAAGCCGAATTGGCGCGTCTCAATCAACCGATCTCCACGTCGTCTTCTTCCTCCTCCTCTAATGGTTCCGCGTCTTCATCATCGTCCACGAGTGGTGCTACAGCCAATCCTCAAATGACGAACCCCTTGCTGGCGAGTGCTGGTTTCGGCAATGGTGAAAATACTAATCCCGATCTGATAGCTCACCTGTGCAATGTGGCCGATCATCGGCTCTACAAGATCGTGAAGTGGTGCAAGAGTTTGCCGCTCTTCAAGCATATTTCGATCGATGATCAAATTTGCTTGCTGATCAATTCATGGTGTGAACTTTTACTTTTCTCCTGTTGTTATCGCTCGATCGATACGCCCGGCGAGATAAAGATGTCACAAGGCAAGAAGATTAGTTTGGCGCAGGCGAAATCAAGCGGTTTGCAGGCTTGCATCGAACGCATGCTCAACATGACCGAGAACTTGAGACGATTACGCGTCGATCGCTATGAATATGTTGCCATGAAAGTTATTGTGTTGTTGCAGTCAGACACCAGCGAACTGCATGAGCCAGTCAAGGTGCGTGAATGTCAAGAGAAGGCTTTACAAGCTTTGCAGGCCTACACGCTTGCCCATTATCCAGATACGCCGTCCAAATTCGGTGAACTATTGCTACGCATACCCGATTTACAAAAGACATGTCaaCTCGGCAAGGAGATGCTCACGATTAAATCTCGTGATGGAGGTGATTTCAATTTACTAATGGAACTACTGCGTGGAGAACATTGA
Protein Sequence: MSSTKAESAVGATPTAVAFASTLTGSAFQLPVSMHSHAQLTANGSSNHNANGTSTTTTSTTTRNNISVTNIKCEMDENIAATLLPNGNLVPVIATTGTAASYYNGTSSGSGGVGIRIPVTKEEDSDSETELTNIENLKVTRRVHNNVDSSSTDGASVISANNINHNKNGPRPMSWEGELSETETTETEFMETENSLSNSGMQTTAATNTLHANIGSSMGVTVIKSETSTTTSGQHNTLAPTPTQAIKPEQMEQICAELQGGAPATFGNVARVGLGSSSSAGSLYTAPHTKLAPTQSDPINLKYEPDASAAHISSGANANSPLLTRNKSATLPLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQGRHAPPASALYGSFNGSLHHSVLYRPITVDSGGGSGATAVNGNSSANNSAGEAKNLSMDTKVSPLNIGLEGLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCPVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLMSPEQQGAAAAAAAVAAAVANQQQHQQGRLGAQMAHTATPRQQTLNGLPAGLGSGQAIIKSEHCDEGSASVRATNIPLLLQEIMDVEHLWQYNEAELARLNQPISTSSSSSSSNGSASSSSSTSGATANPQMTNPLLASAGFGNGENTNPDLIAHLCNVADHRLYKIVKWCKSLPLFKHISIDDQICLLINSWCELLLFSCCYRSIDTPGEIKMSQGKKISLAQAKSSGLQACIERMLNMTENLRRLRVDRYEYVAMKVIVLLQSDTSELHEPVKVRECQEKALQALQAYTLAHYPDTPSKFGELLLRIPDLQKTCQLGKEMLTIKSRDGGDFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00082980;
90% Identity: iTF_01357983;
80% Identity: iTF_00992707;