Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.082 1.1e+02 3.2 0.0 19 46 22 49 16 54 0.86

2 9 0.00024 0.33 11.3 0.1 20 46 88 114 77 117 0.85

3 9 0.026 36 4.8 0.1 21 47 117 143 113 150 0.85

4 9 0.11 1.5e+02 2.8 0.0 21 45 145 169 141 176 0.84

5 9 0.026 36 4.8 0.0 23 45 175 197 170 204 0.90

6 9 1.1 1.5e+03 -0.4 0.0 21 46 201 226 197 229 0.82

7 9 0.12 1.6e+02 2.7 0.1 21 37 229 245 226 260 0.81

8 9 0.12 1.6e+02 2.7 0.0 23 46 287 310 284 314 0.89

9 9 0.015 22 5.5 0.0 22 44 315 337 311 341 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.082	1.1e+02	3.2	0.0	19	46	22	49	16	54	0.86
2	9	0.00024	0.33	11.3	0.1	20	46	88	114	77	117	0.85
3	9	0.026	36	4.8	0.1	21	47	117	143	113	150	0.85
4	9	0.11	1.5e+02	2.8	0.0	21	45	145	169	141	176	0.84
5	9	0.026	36	4.8	0.0	23	45	175	197	170	204	0.90
6	9	1.1	1.5e+03	-0.4	0.0	21	46	201	226	197	229	0.82
7	9	0.12	1.6e+02	2.7	0.1	21	37	229	245	226	260	0.81
8	9	0.12	1.6e+02	2.7	0.0	23	46	287	310	284	314	0.89
9	9	0.015	22	5.5	0.0	22	44	315	337	311	341	0.91

Coding Sequence: ATGAGTGAAAACTGTGATTATGTAACTATTAAGAAATCAAATCTTGCCACTCATTCAAGTACTCATAAAGGAGAAAACTCTTACAGCTGTGAATTCTGTAATAAATCATTTACTGACACAAAAGATCTTACCAGACATTTACATATACATACTAAAGAAAGAACATTTATATGTGAATTTTGTGAGAAATCATTCACACGAAAATCACATCTCACCACACATTTATATACTCACACTGGTGAACAACCATTCATGTGTGGAATTTGGGAAAGACCTTACACATGTGAAATTTGTGAGAAATCATTCAATCAAAAATCCAATCTCACCTCTCATTTACGCATTCATAATGGGGAGAGACCTTACACATGTGAATTTTGTGAGAAATCATTCACTCAAAAACACCAGCTCATCACTCATTTACGTACACATACTGGTGAAAAACCATTCATCTGTGAATTATGTGATAAGTCATTCAATGAAAAATCAAAACTCACCCGACATCTACTCACACATACTGGTGTAAAACCATTCACTTGTAAATTTTGCAATAAATCTTTCACTCAGAAATCAAACTTAATGGTACATTTACGTACACATAATGGGGAAAACCCTTACAAATGTGAATTTTGCAATAAATCTTTCATTCAAAAATCAGCTTTTAATGAACATTTATGTCTACACACTGGAGAAACCCCATTCACCTGTGAAATTTGTGAGAAATCATTCACTCAAAAACACCATCTCATCTCATATTCTCATACACATACTGATGTAAAACCATTCATCTGTGAAATACGTGAGAAATCATTCACTCAAAAATACAGTCTCATCTCTCATTTACTCACACATACTGGTGTAAATCCATTCACTTGTGAATTTTGCAATGAAGCATTCACTCAAAAATCACATCTCACCACGCATCTAGCTATACAATATACTGAAGAAACCCCATTCAAATGTGATTTTTGTGATGCGTCATACTCTCAAAAATCAGCGCTCACCAGACATTTATGTACTCATACTGATGAAAGG
Protein Sequence: MSENCDYVTIKKSNLATHSSTHKGENSYSCEFCNKSFTDTKDLTRHLHIHTKERTFICEFCEKSFTRKSHLTTHLYTHTGEQPFMCGIWERPYTCEICEKSFNQKSNLTSHLRIHNGERPYTCEFCEKSFTQKHQLITHLRTHTGEKPFICELCDKSFNEKSKLTRHLLTHTGVKPFTCKFCNKSFTQKSNLMVHLRTHNGENPYKCEFCNKSFIQKSAFNEHLCLHTGETPFTCEICEKSFTQKHHLISYSHTHTDVKPFICEIREKSFTQKYSLISHLLTHTGVNPFTCEFCNEAFTQKSHLTTHLAIQYTEETPFKCDFCDASYSQKSALTRHLCTHTDER

Sequence clustering based on sequence similarity using MMseqs2