Stum000846.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Scaptomyza tumidula
Gene Symbol
RREB1
Assembly
GCA_035044465.1
Location
JAWNNW010000130.1:682117-688232[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.0054 0.38 11.3 0.6 1 21 234 254 234 256 0.96
2 13 0.00015 0.011 16.2 0.1 1 23 266 288 266 288 0.98
3 13 7.5e-05 0.0053 17.1 7.3 1 23 294 316 294 316 0.98
4 13 0.22 16 6.2 1.7 2 20 542 560 542 562 0.93
5 13 0.015 1 9.9 0.2 1 23 716 738 716 738 0.97
6 13 1.1e-05 0.00081 19.7 0.7 1 23 748 770 748 770 0.99
7 13 0.00077 0.055 13.9 2.0 1 23 776 799 776 799 0.97
8 13 0.0027 0.2 12.2 2.0 1 23 1073 1096 1073 1096 0.95
9 13 8e-05 0.0057 17.0 0.3 2 23 1443 1464 1442 1464 0.97
10 13 0.13 9.5 6.9 6.3 1 23 1470 1493 1470 1493 0.97
11 13 8.7 6.2e+02 1.2 3.4 1 23 1621 1644 1621 1644 0.78
12 13 0.0078 0.55 10.8 0.5 3 23 1706 1726 1704 1726 0.96
13 13 0.0012 0.088 13.3 4.8 1 23 1732 1754 1732 1754 0.99

Sequence Information

Coding Sequence
ATGCTGgccacacaccaacaacaacaacagccagcagcaacaacagcaagcgcaacaacaacagtaagagATAATGATGTTGCTCGCGAGCGTCGTGATTCAAGCACCTCAGAATCCTCGCTGGAACATTTGGATTTGGGCCGAACACCCAAAaagctcagcagcagcagcggtgcGCCGCAGCCAACGTCGACGCCACACAATGCtgtgtcagcagcagcagcgacagcgtcGTCGCGCAAACGCAAACTGCgaccgcaacaacagcaacaattgccgCTGTCCGAtgaggaacagcaacaacagcaactgttagATTCCTCTACACAGCGACCGCGTCACAAGCAGCGACGCAGCGCAGTCGCAGCTGCTGCCAGCGCGAGCATCGTTGTCGACTACAGCGCCAGCGGCGACGCCAGTTCGCTGCGCAAAAAGTTTCGTCTCAATCGCAgcacagcaagcagcaatGGTGGCGCTGCCAACGGTGATTTATCCGAATCGGGTTTCGTTGATGGCAGCACTCACAGTGCTATTCTGCtcaccagcaccaacagcaacatcaacaacaccaacaacagcgcAGTCGCAGCGCAGCAAACATCAAGCGCTAGCAGTTCGGGTGGCTCATCGCCCGAAGGTCTCTCCTCGTACCCATCGAGCGCCGAATCGGGCATCAGTGCCGGCGATGAGCACATGAAATATGTGTGTCCCATCTGTGAGGTGGTCTCGGCCACCCCCCACGAATTCACCAATCATATACGCTGCCACAATTATGCCAACGGCGACACCGAGAACTTCACCTGCCAAATCTGCTCCAAGGTTCTCTCATCGGCATCCTCCCTAGATCGCCATGTGCTAGTCCATACGGGAGAGCGTCCGTTTAACTGTCGCTATTGCCACTTGACCTTCACCACGAACGGGAATATGCATCGTCATATGCGGACACACAAGCAACATCAGACatcccaacagcagcagcagtcgcaacagcaacagcaatcccaacagcagcagcaacaatcgcaACCACAACAGCGACGCCAGCAACacggaggaggaggaggagcaggagcaacTGGCTCGGGATCGGGATTGGGATCGGGtgtacagttgttgttgccagctcGTGCGGAGAGCTATGAGAGTGATGCCAGCTGCTCGACAGATGTGTCCAGTGAGGCGAACAGtcacagcgacagcaacagtcatcacaacaacaacaacaacaatacacacaaaacaaacaacaataacaacaacgagaatGAAATGGAGCTGGAGAATGAGATAAAGCAGCGACGCCGCAAAACCctgaataataacaacaacattgtaaGAGATGAACATGATCGgatggaggaggaggaggtggaggagcAGGAGGATCGGCATGATGATGCTGATTCGGATGTGGATAGTGTTGATAGTGTTGCCCAGGTCATAACCAGTACACCAGATGTTGCAACTCTGCTCGCCTCGGGTGGCACCTCGCCCACCCACTCGCATTCGCCCTCACCGCCCCTGCTCCGGCTGCAGAGCTGCCCGGCCTGCAATATGGGTGAATTTGAATCTGTGCCAGCGCTGTGCGCTCATTTGGATGCCGAGCATTCGGACATACCGGCCAAGTGTCGGGAGTGTGAGGTCATCTTTGCCACACATCGACAGCTGCAGGCGCACAGTTGTCGGGGTTTACCGCCGCTTCTCGGTGTTAGTTCCTCCCCGCTGCACAAGCAGGAGGaagacgacgaagacgacgacgacgacgaagaccaGCACCAACACCAGGAGGAAGAGGATGATAATGATGTGGATGGGCATGGAAATGGGGAGAAGGAACAGTTGGAGCAGCGAGAATGTGAAGACTTCTTTCAGCAACTGTACCTCAAGAACAAAGCCTCAACAGCGACAACCCTACTACCCTCCCCCATCAAACATGAGCCGACGGATCAGCGTCAGGATCTAGCCGATATCCAAAGCATTCTTAACATGACCAGCTCCAGCTGCACCTCAAGCTTTCTGCGCAACTTCGAGCAATCGGTTAACACACCCTGCTCCAGCCAGTACAGCGTCGACGGACGCGATGGCGAAGAGGAAGCACAGGATGCCTTCACCAGTGAATTCCGACGCATGAAGCTACGCGGTGAGTTTCCCTGTAAACTGTGTACCGCCGTCTTTCCCAATCTGCGTGCGTTGAAGGGACACAATCGCTACCATCTATCGGAGGTGGGAGCTACCGGACCCTTCCGTTGCAACATGTGCCCCTATGCCGTTTGCGACAAGGCAGCCCTGGTACGTCACATGCGTACCCACAATGGGGACCGTCCGTACGAGTGTGCTGTCTGCAATTATGCCTTCACCACCAAGGCCAACTGTGAGCGACATTTGCGCAATCGTCATGGCAAGACGAGTCGCGAAGAAGTCAAGCGTGCCATTGTCTATCATCCGGCCGAGGATGCCAGCTGtgaggacaacaacaatagatcACGTTCCGATGGCGACCTTCTCACCGAAGGTGCtaatggtaatggtaatggtgGTGGTAGTGGTTATCgttgtgccacgcccacagaGCACAGTTCCTCGGCCAGTTCGTCGCAGTCACAGCTTAAGCACATGTTGCTGGCggacgcaacagcaacaccagcaacagtagcaacagtagcagcaacacaGCAACCACCACTGAAGATCCAAGTAAAGAGTTTGGATCAGCTGGTGGATAAGCCGATGCCAGCTTTAGATCTGAGCATGGATGTGCTGGACTTGAGCAAGAAGCCGGCACAGCTGCTAACAGAGCAAAGGGAGCAGAGGGAGCAGCTCGAAAGACATGAATTGctactgcaacagcaacagcagcagccgcaacaacagcagcagcagcaacagccacaacaaccaTTGTTTGGCGCTGGAGATGCTGCCACACAGTAcatgcaacagctgttgcgCAACTTTATGTTGCAACAATCACCTGGATTTCCGTTCTTTGGCTTTATGGCGCCACCGCCACCAGCAGCatcagttgcagctgcagcagcagcagcagagaaattgttaccaacaacaaatgcaaatgcaactgcattGCCGCTGTCACTACCAGTGCCactgcccctgcccctgcccaTGCCAGCCGGTGGACCGGTCAAGATGGTCATCAAGAATGGTGTCCTGATGccgaaacaaaagcaacggcGCTACCGCACCGAACGTCCCTTTGCCTGCGAGCATTGCTCGGCGCGATTCACTCTACGCTCGAACATGGAGCGACATGTGAAGCAGCAACATCCCACCCACTATGCAACACGACAGCGCAGTGGACATCATGTGATGCGTGGACGTGCTGCATCCAGTCAGGCTCAAGCTCAAGCTCATGCggctgcagcggcagctgctgcagcagcaatgaGCAATCTtacccaacagcagcagcaacactccCATGCCCATCATCATGTTCATGCCCCGATTTCAGAGCAGGTCAAATATGCGATCTTGACACAACAGTTGAAGGCGCGCAAGGATACCGATCTGTTGCAGCAGGCACTCGCACATGGCTCAAGTAGTGTCGTTCCAAATCCTTTTCTACATTTTGgctacaccaacaacaacaacatcagtaacagcaacaagcaacaacagcaacagttgcaggtGCTGGATGATGATGAGCCGCCCAAACTAATCATTGACGAGGATGATGAAGATGTCGAGGGTTgtgtcgacgacgacgacgaagaggaagaggaagaggagcAGGATTTTGATATAGACGAAGATGAGGAGCAGGAAGGAGCTGAAGAgatcgagcagcagcagcacaggcAAGAGGAGACGACCAAGACTACCAAACCCATGGAGGCAGCCAAAAAGGTTGCCGAAATCATTCTCGAGCAAGCAACCAAGGAGCAAGTGGATCAAcagccaacaccaacaacaacaccaccaacatcacaacaaaagcaacagcaacaacaacaagttgcacctccaacaacaatgaaaactaTGATTGCCCAAGCCGAATCGGTGGCCAAATCCCTGAAAGAAGTCGCCAGTTCACCGTTCAAGGATGAATCTCAGGATCTGGTGCCGGTAGCCAAACTAGTGGACAATGCAACCAGCAATCAGGTGTCGTTCAACAGCTATTTTCGACCCAGCGACGTTGCCAATCACATGGAGCAGAGCGATGAGGAAGGTCTCGTTGCCAGTGGTAGCGCCAGTGAGAGTAACAATTCCGGAACCGAAGATGTTACCAgctccagcagcagctgtggcaATGATACAAAGAAAAAGTCCGCATACAGTTTGGCACCCAATCGGGTCAGTTGTCCCTATTGCCAGCGCATGTTCCCTTGGAGCAGCTCGCTGCGCCGTCACATCCTCACCCATACGGGACAGAAGCCCTTCAAGTGTTCCCATTGCCCGCTTTTGTTCACCACCAAGAGCAACTGCGATCGCCATCTGTTGAGGAAGCATGGCAACGTTGAGTCCGCAATGTCCGTGTATGTGCCAACCGAGGATGTGAGTGAGCCCATACCGGTGCCCAAGTCGGTGGAGGAGATCGAGCTGGAGGAGCAGCGCCGGCGTCAAGCCGCCGAAGCTGAGCATGCCGAACGCGAAAGGGAAAGGGAGCGTGAACGCGAGAAGGAGCGGGAACGTGATCGTGAacgtgaacaacaacaattgatacAACAATTGCGTCAAcaaatggctgctgctgctgctgcagctgcaactgctgccgttgccgccgccaccgccgccgccaacgTTGTTGCCGTCGCGCCAGCTCCAGCTTCATCTCCATCGCCAGCACAATCACCACCCGGTGGTGTGGAAGCAAGCAGTGATCTGCCCTACAAGTGTCATCTGTGCGAGTTCTCCTTTGGCGAACGTTTGCAGTGCCTGGAGCATATCAAGCAGTTGCATGCCCATGAGTTTGCACTCCTACTGGCCAAGGGTGCTATCGAAACGGatgcacaacagcagcaacagttgccagcTAATTCGCATTCGGATGATGaggcaatagcagcagcagcagcagcagcatctgttGTTGGCATCAGATCTGGTGGCAAATATCCCGACTATAGCAATCGTAAGGTGATCTGCGCCTTTTGTGTGCGTCGCTTTTGGTCAACGGAGGATTTGCGACGACATATGCGTACGCATTCGGGCGAACGTCCGTTCCAGTGCGAGATCTGTTTGAGGAAGTTCACGTTGAAGCACAGCATGTTGCGGCACATGAAGAAGCACAATGGACGCAGTCACAATGGTGGTGAGCTGGATCATCAATCGGATTGCTCCGATGATGAACAAATGATGTCATGTTCGCCACCCACAACGCCAAcacccaccaacaacaacaacagcaacacttgccagaacaacaacaacaataccagcaacaataacaacaacaccaacacaaagcAAGTACTGCGAGAACTTTTGGGCAAAGCGAACGAGCTGCGTATCAATCGTTTGGCTGGTGCCGAGCACAAGGAGAACATtgccgaagcagcagcatcagcagcagcaacaacaacagcagcagcagcaacgagtGTTGCCAGCGGTGATTTAATTGGTAATCTTTTGGGTATCAGTGATCAGGGCATACTCAATAAGTTGCTCTCCTCACCCGACGAAGCTGCCAAGCTGCTCGGCGTGGAGAagtaa
Protein Sequence
MLATHQQQQQPAATTASATTTVRDNDVARERRDSSTSESSLEHLDLGRTPKKLSSSSGAPQPTSTPHNAVSAAAATASSRKRKLRPQQQQQLPLSDEEQQQQQLLDSSTQRPRHKQRRSAVAAAASASIVVDYSASGDASSLRKKFRLNRSTASSNGGAANGDLSESGFVDGSTHSAILLTSTNSNINNTNNSAVAAQQTSSASSSGGSSPEGLSSYPSSAESGISAGDEHMKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCQICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQTSQQQQQSQQQQQSQQQQQQSQPQQRRQQHGGGGGAGATGSGSGLGSGVQLLLPARAESYESDASCSTDVSSEANSHSDSNSHHNNNNNNTHKTNNNNNNENEMELENEIKQRRRKTLNNNNNIVRDEHDRMEEEEVEEQEDRHDDADSDVDSVDSVAQVITSTPDVATLLASGGTSPTHSHSPSPPLLRLQSCPACNMGEFESVPALCAHLDAEHSDIPAKCRECEVIFATHRQLQAHSCRGLPPLLGVSSSPLHKQEEDDEDDDDDEDQHQHQEEEDDNDVDGHGNGEKEQLEQRECEDFFQQLYLKNKASTATTLLPSPIKHEPTDQRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSVDGRDGEEEAQDAFTSEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRYHLSEVGATGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDASCEDNNNRSRSDGDLLTEGANGNGNGGGSGYRCATPTEHSSSASSSQSQLKHMLLADATATPATVATVAATQQPPLKIQVKSLDQLVDKPMPALDLSMDVLDLSKKPAQLLTEQREQREQLERHELLLQQQQQQPQQQQQQQQPQQPLFGAGDAATQYMQQLLRNFMLQQSPGFPFFGFMAPPPPAASVAAAAAAAEKLLPTTNANATALPLSLPVPLPLPLPMPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPTHYATRQRSGHHVMRGRAASSQAQAQAHAAAAAAAAAAMSNLTQQQQQHSHAHHHVHAPISEQVKYAILTQQLKARKDTDLLQQALAHGSSSVVPNPFLHFGYTNNNNISNSNKQQQQQLQVLDDDEPPKLIIDEDDEDVEGCVDDDDEEEEEEEQDFDIDEDEEQEGAEEIEQQQHRQEETTKTTKPMEAAKKVAEIILEQATKEQVDQQPTPTTTPPTSQQKQQQQQQVAPPTTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSCGNDTKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQAAEAEHAEREREREREREKERERDREREQQQLIQQLRQQMAAAAAAAATAAVAAATAAANVVAVAPAPASSPSPAQSPPGGVEASSDLPYKCHLCEFSFGERLQCLEHIKQLHAHEFALLLAKGAIETDAQQQQQLPANSHSDDEAIAAAAAAASVVGIRSGGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHNGRSHNGGELDHQSDCSDDEQMMSCSPPTTPTPTNNNNSNTCQNNNNNTSNNNNNTNTKQVLRELLGKANELRINRLAGAEHKENIAEAAASAAATTTAAAATSVASGDLIGNLLGISDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01326640; iTF_01320657; iTF_01321367; iTF_01325848; iTF_01327352;
90% Identity
iTF_01321367;
80% Identity
-