Basic Information

Insect: Scaptomyza polygonia
Gene Symbol: Dp
Assembly: GCA_035044585.1
Location: JAWNNU010001690.1:159176-163952[-]

Transcription Factor Domain

TF Family: E2F
Domain: E2F_TDP domain
PFAM: PF02319
TF Group: Helix-turn-helix
Description: This family contains the transcription factor E2F and its dimerisation partners TDP1 and TDP2, which stimulate E2F-dependent transcription. E2F binds to DNA as a homodimer or as a heterodimer in association with TDP1/2, the heterodimer having increased binding efficiency. The crystal structure of an E2F4-DP2-DNA complex shows that the DNA-binding domains of the E2F and DP proteins both have a fold related to the winged-helix DNA-binding motif. Recognition of the central c/gGCGCg/c sequence of the consensus DNA-binding site is symmetric, and amino acids that contact these bases are conserved among all known E2F and DP proteins.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 7.9e-24 7.3e-20 71.1 0.3 2 65 174 250 173 250 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	7.9e-24	7.3e-20	71.1	0.3	2	65	174	250	173	250	0.97

Sequence Information

Coding Sequence: ATGGCGCATAGCTCAGCAACAAATCAAACGAGTGGCGCGGTCAAGACAGATGAAGTCAACTATTTCTTTCAGGATGAGCACGGACAAATTGCTAAAATGTTGAAACCGGTACAAGTGAAGCAAACGCAATCATCCATGGACAATTCGAAGTCCAGTTTGGTCTTCCCCAGCGTCTCAACACGCAACGTTGGCGGCGGCATTGGCACAGTGGGCCGAATGGGCGCCTTCAGTCAGATGGGCTCAACGAATCAGGGACAATTTATACGACTTCAAGACAGTTGTATAACTATTCCAAAAACTGAAAATATTTCATATATCGCACCTGTGTCATCGCAGAAGGGCAGTGGAGGCAGCATGCACGAGGTGATAAAGAACGAACGATATACGCCATATACGAAATATACGCCAAATAACGCCATGAAAATGAAATCGAAATTGCAAACTATACAGAGCAATTCCATGCACACAATGCCCGCCTCTACATCATCAGTGCAAAGGAAACGAAAGCCAGATAAGGCTGGCAAAGGACTGCGTCATTTCTCGATGAAGGTGTGCGAAAAGGTGCAGGAGAAGGGCAAGACAACGTATAATGAAGTTGCCGATGATTTAGTTGCGGAAGAACTGAAGAATAATTCATACGATAACAACTGTGATCAAAAGAATATCCGACGTCGTGTTTACGATGCGCTCAACGTACTGATGGCAATCAATGTTATTTCCAAGGACAAAAAGGAAATACGTTGGATTGGCTTGCCCGCCAATTCGGCAGAGCAATTTCTGGCTGTGGAAATGGAGAACAAATCGCGTCGTGAACGAATCAAGCAAAAACGTGAAATGCTTCGTGAAATGGTTATGCAACATGTGGCGTTCAAGGGTCTCGTTGAACGCAATAAACGTGCCGAGAGCCAAGGCGTCGTGCCATCCCCAAACTCATCCATTCAGCTGCCTTTCATCATTGTCAATACGCACAAATCGACAAGGATCAATTGCAGTGTCACCAACGACAAaTCGGAGTACATATTCAAGTTCGACAATACATTCGAAATGCACGATGACATCGAGGTTTTGAAACGCATGGGTCTTCTGCTGGGTTTGGACAAAGGTGAATGCACGGCCGAGAATATTGAACAAGTCAAGTCTTGGGTTCCACCAAATCTGGCCAAATATGTTGAAGCGTATGGCACTGGTAAAATGTGTGATCCGATGTACGATTCGGATGACGAGGACAACGTCTTTAATACGTATCATGAAACAAACAATGATTCTCCAATCTTTGCACAACGCACACAGCATAGCAACGATGTGGAATTCAAGCTGGAGCTGGATGATGATGAGCTGGAGGATGACATCGATTGA
Protein Sequence: MAHSSATNQTSGAVKTDEVNYFFQDEHGQIAKMLKPVQVKQTQSSMDNSKSSLVFPSVSTRNVGGGIGTVGRMGAFSQMGSTNQGQFIRLQDSCITIPKTENISYIAPVSSQKGSGGSMHEVIKNERYTPYTKYTPNNAMKMKSKLQTIQSNSMHTMPASTSSVQRKRKPDKAGKGLRHFSMKVCEKVQEKGKTTYNEVADDLVAEELKNNSYDNNCDQKNIRRRVYDALNVLMAINVISKDKKEIRWIGLPANSAEQFLAVEMENKSRRERIKQKREMLREMVMQHVAFKGLVERNKRAESQGVVPSPNSSIQLPFIIVNTHKSTRINCSVTNDKSEYIFKFDNTFEMHDDIEVLKRMGLLLGLDKGECTAENIEQVKSWVPPNLAKYVEAYGTGKMCDPMYDSDDEDNVFNTYHETNNDSPIFAQRTQHSNDVEFKLELDDDELEDDID

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00541568;
90% Identity: iTF_01320262; iTF_01320984; iTF_01322434; iTF_01323172; iTF_01325455; iTF_01327683; iTF_01326957; iTF_01324694; iTF_01323904; iTF_01321710;
80% Identity: -