Smon013622.1
Basic Information
- Insect
- Scaptomyza montana
- Gene Symbol
- -
- Assembly
- GCA_018904305.1
- Location
- JAEIGR010000002.1:12311355-12320386[-]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 1.5e-13 6e-10 38.7 0.1 10 72 408 466 401 469 0.88
Sequence Information
- Coding Sequence
- ATGGACAACATCGGAATGAATTCGATGAATAGAGGACTTAAGCTCTGGAACTGGATGAAGGTTGAGAGTTTAACGTTAGTTTCGGATCTTTGCATGTACTTCTGTGTCTGGACTGCTATATTCGTGCTGAGGCTGTGGAATCGTTGTTCCAAATTGACTCGCAAATTGCTCAAGATGAGTTCGAATAGACCCAGCCGTTCGAGATCGCGATCATTTTATTTTGATTCAAGCTCAGCTAGCTCTTCTTCGGCATCATCGTGGAAGGCAGCCTCAATGGAAGTAAATGGTGACACACCTAGCCCTTCACGCAAGCAAAAGAAGAAAAATAACAAGAAGAGCCATGATCATAAGGAGAATGCTGTACTAGGCTGGGGCACCACATACCCCAATCTTGTGTCATCGGTTAGCATGGACAGCCTCTCTGATACGGATATGCCACTACCCACTGACTTAAGGGCATTTTGTGCCAGTGGGCTCGGCATCTTTCCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTCAGATTCTGTTCCCTCCTCACCACTTACTCAACTTAACCTAGACTTAGCGACAACAACTAATCAACTAAACACAACAACAACTACACCAACAACAACTAATATCTCACCCATCACAAAATTAACTGCTTCATGTCCACACTCTATGAAGACAGCAACAACAATCAGCGTCGACAATATAACCAGTGATATCAGTAATACAATTGTTACCAGCAGAATCGAGAACATTTCAACAACAACATCCCTTCCTCGTTACAAACCATCAAGAGTCCAACAAAGATCAAAATCAGATTCAGAATTAGAAACTGATTTACAAAAGCAGAGAAAGAAGCTTTTCAAGAAAAGCTCGACCAAAAGTGCTGAAAAGATGCGCCCAAACAGTTGTTTTAAGCACGATGATGAATCATCGGACGATGAGCCGGAGATTACGAAGCGCTCAAAAAAATCGGATTTGGAATTGGATCCAACAAACTCGCCAAACGTTAAGAAGGAGGACAAGAGAGTATTGCGCAAGCGCGCAAAATCGATGTATGTAGCCGATCCGGACTTCAACATGAATATTGGTGAAATAGCTAAAAAGAAACCGCCAGCACGCCGTCGTTCGGTTTATGCTAAGCTGCTGCCCGATGATCCTGAGGATCCCTTTTATCTCGCGCCATTCCAAAATGGCTGGAAGCGTGAGCTAGTGCAGCGTAACACTGATAACAATAAACGTCAGCGTACTGAAGTCTTTTTTATATCGCCATTTGGCAAAAGGCTGCGCACACGCGATGAAATTAGTAAGCTGCTTCCGGTCGGTCTTAACATTGAACATTTTTGTTTCATACCCCGTTTGCAAGGAGTTGGAGAGCCTGACGAGACATTCCGTCATGTTGTTCCGGAACGTCGCAAATCCATGAACGTTGCCAAGCAGATAAGTAAGGAAGATAAAATCCCGATGCAGCAACAAAAAGAAGGATTAAAGCAAAAGGCCCAGCTGGTGGTCAAACAAGAAGAGAAGCAACAACAGCAAATCAAACAACAAGAGCATCCAAAGCAACAGCAACCGAAACACACGAAGCAACTGAAGCAACAAAAGACCAACAACAACTTGGGCCAACAACAAACGCTTGTTTCTGGTAAACGTGTGCCAAAACCTAAGGCGCCCAAGGGGGCTAGCCCACCGCCGAATGGTTGGACCTCAACTATGGCGGTTTTGGGAAATGGTCGCGTCTTAGCCACGAAACATAATAATAGCAGCAGTGGTGCTGGTTTCAGTGGTGGAAACGCTGCTCGCAAACGCAACAGCAACGCTAACAAATCAGTAAAGCTAGCAACAGAGACGACTGTTGGGCCGCCAAAGCTGCCGGTGGAGCCGGAGCCCGTCGTTAAGGAGAAGACTTGTTCGAAGTGCCTTCAGCCAATAATAAATGAAGTCAATACAACCGTTTCAACTGACGAATCCACCCATTGCTGTCGTCGTTGTCTGGGCAAGGTCGTTGCCGACGAGAATGATGACGGCGTTGGCCAAGGCATCATGCAGCGCATCGCCGAAGAGCTTGAGCGTCCTGGCGCCTTGCCGCCAGCCAAACTGCTGCGCGACGATTCACCTGCACGTCCCGGCGGTAAGATCACTCCCAAGCCGATGGAGGTTGTCGTCTTGAACGGACGCAAGGCTGTCGCCATTTCTGACGCGCAGCCACGTATGCATCACTTACAACTCTTTTCAGATGAATCGACCTTGAATATCTTTGCAAAATTTTATTCCAAACGCAACGCTACAGCAAAGGAGAAGCGTCAACAAGTCAATGATTGCATATCCGCTGGCAACAAGGGCTGTCAATTGATGACGGCCATTATGAAGACGCTCGACATGCAAGAGCGTGTGCGCTTGTCAAAAGTGTGCAAGACCTGGGCTATGATAGGCCGCGATCGCAGCGTGTGGCGCACAGTCAAGTTGCGCAACACACACATCACCAACTGGTCGTTACTGCTGCGTGATATGGCGCGCTATTGCACCGACGAATTCGATATGATGGGCGTGATAATCAAAAATCCCCGGATGCTCAAAGAAGGAGATTGGGGAAAACTGAAATCATTGCGCATTTTGCGCACAGATGCTAGAGATGCAGAGATTATCGAGTCAATTATCAAGGGAATGCCACACTTGCAAGAAATGCGCACAACATGCACCAGTCCAGCTTTGAATCTGGCCAATATTGAAAAGATGATCGGATTGCGTGTGCTTCGCATTCGCATGTTGGAGGCTAAGGCTAGGATTGTTTCGTTGTCGCCGCTGCAGAATCTGTTCTGTTTGAATGAACTGAGTTTGCGTGGCATTACCAACATGGATGTGCTGGATCTGTTGCAGCTTAAAGACTTGCCACATCTGGAGACGCTTGTGCTGGGCTCGTGTCGCGGCATGGAGGTGATATCATTTGGAGCAGAAGTTCTGCCCAGTTTAAAGCGTTTGCGCCATCTTCGCCTGGAGAATCATCACAGTAGTAGCAGCTTTATTATTAAAGAGATTATGGACGGCATTGCCGCCGGTGGCAGTGTGCAGCGTCTTGAGCTTATCAATGTCAATATCGATGCAGAGTTAAGCCGTCAGTTGTCCGAGTGCAAATCGTTGAATGAACTGCTGCTGATGCCAGATTTTCATAATAATTCCGCGTATGTGGTGCACTACATCATGCAGGCCATCAATGAGAATAGTGAACAACTCAGCGTGTTCTGTCTGGGTATTACCAATGAACTCCTCAGGGTGACTCGCGCATTGGCCATGATCAAGGACAAGGACATCATACCTGTGGTGCTGCCCATACCGGGCGTCCCCGACAATGATACATTAAATGAGTCAGAGTGTGGAATCGGCTATTTACCGGTCGATCGCCTTGAATCGATTTTACATCATATGATGCCACAAGCTTGGCTAACAGTCTCCAAGGTTTCGCAACTTGAGACAATCAACATGAAATTCTTGCCAGCTCCTGCTCGTAAAGACAAAGTTGGCGGCTTTTCAAGCAATTAA
- Protein Sequence
- MDNIGMNSMNRGLKLWNWMKVESLTLVSDLCMYFCVWTAIFVLRLWNRCSKLTRKLLKMSSNRPSRSRSRSFYFDSSSASSSSASSWKAASMEVNGDTPSPSRKQKKKNNKKSHDHKENAVLGWGTTYPNLVSSVSMDSLSDTDMPLPTDLRAFCASGLGIFPXXXXXXXXXXXXXXXXXXXXXXXXXXSDSVPSSPLTQLNLDLATTTNQLNTTTTTPTTTNISPITKLTASCPHSMKTATTISVDNITSDISNTIVTSRIENISTTTSLPRYKPSRVQQRSKSDSELETDLQKQRKKLFKKSSTKSAEKMRPNSCFKHDDESSDDEPEITKRSKKSDLELDPTNSPNVKKEDKRVLRKRAKSMYVADPDFNMNIGEIAKKKPPARRRSVYAKLLPDDPEDPFYLAPFQNGWKRELVQRNTDNNKRQRTEVFFISPFGKRLRTRDEISKLLPVGLNIEHFCFIPRLQGVGEPDETFRHVVPERRKSMNVAKQISKEDKIPMQQQKEGLKQKAQLVVKQEEKQQQQIKQQEHPKQQQPKHTKQLKQQKTNNNLGQQQTLVSGKRVPKPKAPKGASPPPNGWTSTMAVLGNGRVLATKHNNSSSGAGFSGGNAARKRNSNANKSVKLATETTVGPPKLPVEPEPVVKEKTCSKCLQPIINEVNTTVSTDESTHCCRRCLGKVVADENDDGVGQGIMQRIAEELERPGALPPAKLLRDDSPARPGGKITPKPMEVVVLNGRKAVAISDAQPRMHHLQLFSDESTLNIFAKFYSKRNATAKEKRQQVNDCISAGNKGCQLMTAIMKTLDMQERVRLSKVCKTWAMIGRDRSVWRTVKLRNTHITNWSLLLRDMARYCTDEFDMMGVIIKNPRMLKEGDWGKLKSLRILRTDARDAEIIESIIKGMPHLQEMRTTCTSPALNLANIEKMIGLRVLRIRMLEAKARIVSLSPLQNLFCLNELSLRGITNMDVLDLLQLKDLPHLETLVLGSCRGMEVISFGAEVLPSLKRLRHLRLENHHSSSSFIIKEIMDGIAAGGSVQRLELINVNIDAELSRQLSECKSLNELLLMPDFHNNSAYVVHYIMQAINENSEQLSVFCLGITNELLRVTRALAMIKDKDIIPVVLPIPGVPDNDTLNESECGIGYLPVDRLESILHHMMPQAWLTVSKVSQLETINMKFLPAPARKDKVGGFSSN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01321916;
- 90% Identity
- iTF_01321916;
- 80% Identity
- -