Basic Information

Insect: Scaptomyza flava
Gene Symbol: -
Assembly: GCA_003952975.1
Location: RKRM01000002.1:303668-310236[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 5.4e-14 2.2e-10 39.9 0.1 10 72 338 396 331 399 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	5.4e-14	2.2e-10	39.9	0.1	10	72	338	396	331	399	0.88

Sequence Information

Coding Sequence: ATGAGTTCGAACAGACCCAGCCGTTCGAGATCGCggtcattttattttgattcaaGCTCAGCTAGCTCTTCTTCGGCATCACCGCGGAAGGTAGCCCCAATGGAAGTTAATGGTGACACACCTAGCCCTTCACGcaagcaaaagaagaaaaagaacaagaagagCTATGATTATAAGGAGAATGTTGTACTAGGCTGGGACACCATATACCCCAATCTTGTTTCATCGGCTAGCATGGACAGCCTCTCTGATACGGATATGCCACTACCCACTGACTTAAGGGCATTTTGTGCCAGTGGGCTCGGCATCTTTCCCAGAGAGGAAAAGGAGGAGCCGCCGCCGCTATCAACACAGCCGCCACCGCCGCTGTCCTCATCACCGTCTTCAGATTCGGTTCCCTCCTCACCACTTACTCAACCTAACTTGGACTTAGCGACAGCAACTAATCAactaaacacaacaacaactaatatCTCACCCATCACAAATTTAACTGCTTCATCTCCACACTCTAtgaagacagcaacaacaaacagcgtCGACAATATAACCAGTGATATCAGTAATACAATTGTTACCAGCAGAATCGAGAACATTTCAACAACAGCATCCCTTCCTCGCTACAAACCATCAAGAGTCCAACAAAGATCAAAATCAGATTCAGAATTGGAAACTGATTTACAGAAGCAGAGAAAGAAAAGTTCGACCAAAAGTGCTGAAAAGATGCGCCCAAACAGTTGTTTTAAACCCTATGATGGATCATCGGACGATGAGCCAGAGATCACGAAGCGCTCAAAAAAATCGGATCTGAAATTGGATCCAAAATACTCGCCAAACGTTAAGAAGGAGGAGAAGATAGTATTGCGCAAGCGCGCCAAATCGATGTATGTGGGCAATCCGGACGTCAACATGAACAGTGGTGATATAGCTAAAAAGAAGTCGCCAGCACGCCGTCGTTCGGTTTGTGCTAAGATGCTGCCCGATGATCCTGAGGATCCCTTTTATCTTGCGCCATTCCAACATGGCTGGAAGCGTGAGCTAGTGCAGCGTAACACTGATAACAATAAACGTCAGCGTACTGAAGTCTTTTTTATATCGCCATTTGGCAAAAGGCTGCGCACGCGCGATGAAATTAGTAAGCTGCTCCCGGTCGGTCTTAAcattgaacatttttgtttcataCCCCGTTTGCAAGGAGTTGGAGAGCCTGACGAGACATTCCGTCATATTGTTCCGGAACGTCGCAAATCCGTGAACGTTGCCAAGCAGATAAGTAAGGAAGATAAAATCCcaatgcagcaacaaaaagaaggaTTAAAGCAAAAGGCACAGCAGGTGGCTAAACAAGAAGAGAAGCACCAACAGCAAGTCAAACAACAAGAGAAtccaaagcaacagcaagcaaaacaaacgaagCAACTGAAGCAACAaaagaccaacaacaacttggcTCAACAACAAACTCTTGTTTCTGGTAAACGTGTGCCAAAACCTAAGGCGCCCAAGGGGGCTAGCCCACCGCCGAATGGTTGGACCTCAACTATGGCGGTTTTGGGAAACGGTCGCGTCTTGGCCACGAAACATAATAATAGCAGCAGTGGTGCTGGTTCCAGTGGTGGAAATACCGCTCGCAAACGcaacagcaacgctAACAAATCAGGAAAGGTAGCATCAGAGACGACTGTTGGGCCGCCAAAGCTAACGGTGGGGCCGGAGCCAGTCGTTAAGGAGAAGACTTGTTCGAAGTGCTTTCagccaataataaatgatgTCAATACAACCGTTTCAACTGACGAATCTCTCACCCATTGCTGTCGTCGTTGTCTGGGCAAGGTCGTTGCCGACGAGAATGATAACGGCGTTGGCCAAGGCATCATGCAGCGCATTGCCGAAGAGCTTGAGCGTCCCGGCGCCTTGCCGCCAGCCAAACTGCTGCGCGACGATTCACCTGCACGTCCCGGCGGTAAGATCACTCCCAAGCCGATGGAGGTTGTCGTCTTGAACGGACGCAAGGCTGTCGCCATTTCTGACGCGCCGCCACGTATGCATCACTTACAACTCTTTTCAGATGAATCGACcttgaatatttttgcaaaattttattCCAAACGCAACGCTACAGCAAAGGAGAAGCGTCAACAAGTCAATGATTGCATATCCGCTGGCAACAAGGGCTGTCAATTGATGACGGCCATTATGAAGACGCTCGACATGCAAGAGCGTGTGCGCTTGTCAAAAGTGTGCAAGACCTGGGCTATGATAGGCCGCGATCGCAGCGTTTGGCGCACAGTCAAGTTGCGCAACACAAACATCACCAACTGGTCGTTACTACTGCGTGAAATGGTGCGCTATTGCACCGTTGAATTGGATATGATGGGCGGGATAATCAAAAATCCCCGGATGCTCAAAGGAGGAGATTGGGGAGAACTGAAATCATTGCGCATTTTGCGCACAGATGCTAGAGAGGCAGAGATTATCGAGTCAATTATCAAGGGTATGCCACAATTGCAAGAAATGCGCACAACATGCACCAGTCCAGCTTTGAATCTGGCCAATATTGAAAAGATGATCGGATTGCGTGTGCTTCGCATTCGCATGTTGGATGCTAAGGCTAGGATTGTTTCGTTGTCACCGCTGCAGAATTTGTTCTGTTTGAATGAACTGGGTTTGCGTGGCATTACTAACATGGATGTGCTGGATCTGTTGCAACTTAAGGACTTGCCACATCTGGAGACGCTTGTGCTGGGCTCGTGTCGCGGCATGGAGGTGATATCATTTGGAGCAGAATTTCTGCCCAGTTTGAAGCGCTTGCGCCGTCTTCGCCTGGAGAATCATCACAGTAGTAGCAGCTTTATTATTAAAGAGATTATGGACGGCATTGCCGCCGGTGGCAGTGTGCAGCGTCTTGAGCTTATCAATGTGAATATCGATGCAGAGTTAAGCCGTCAGTTGTCCGAGTGCAAATCGTTGCATGAACTGCTGCTGATGCCAGATTTCCATAATAATTCCGCTTATGTGGTGCACTACATCATGCAGGCCATCAATGAGAATAGTGAACAACTCAGCGTGTTCTGTCTGGGTATTACCAATGAACTCCTCAGGGTGACTCGTGCATTGGCTATGATCAAGGACAAGGACATTATACCTGTTGTCCTGCCCATACCGGGCGTCCCCGACAATGATACATTAAATGAGTCAGAATGTGGAATCGGCTATTTACCGGTCGATCGCCTTGAATCGATTTTACATCACATGATGCCACAAGCTTGGCTAACGGTCTCCAAGGTTTCGCAACTTGAGACAATCAACATGAAATTCTGGCCAGCTCCTGCTCGTAAAGACAAAGTTGGCTGCTTTTCACGCAATTAA
Protein Sequence: MSSNRPSRSRSRSFYFDSSSASSSSASPRKVAPMEVNGDTPSPSRKQKKKKNKKSYDYKENVVLGWDTIYPNLVSSASMDSLSDTDMPLPTDLRAFCASGLGIFPREEKEEPPPLSTQPPPPLSSSPSSDSVPSSPLTQPNLDLATATNQLNTTTTNISPITNLTASSPHSMKTATTNSVDNITSDISNTIVTSRIENISTTASLPRYKPSRVQQRSKSDSELETDLQKQRKKSSTKSAEKMRPNSCFKPYDGSSDDEPEITKRSKKSDLKLDPKYSPNVKKEEKIVLRKRAKSMYVGNPDVNMNSGDIAKKKSPARRRSVCAKMLPDDPEDPFYLAPFQHGWKRELVQRNTDNNKRQRTEVFFISPFGKRLRTRDEISKLLPVGLNIEHFCFIPRLQGVGEPDETFRHIVPERRKSVNVAKQISKEDKIPMQQQKEGLKQKAQQVAKQEEKHQQQVKQQENPKQQQAKQTKQLKQQKTNNNLAQQQTLVSGKRVPKPKAPKGASPPPNGWTSTMAVLGNGRVLATKHNNSSSGAGSSGGNTARKRNSNANKSGKVASETTVGPPKLTVGPEPVVKEKTCSKCFQPIINDVNTTVSTDESLTHCCRRCLGKVVADENDNGVGQGIMQRIAEELERPGALPPAKLLRDDSPARPGGKITPKPMEVVVLNGRKAVAISDAPPRMHHLQLFSDESTLNIFAKFYSKRNATAKEKRQQVNDCISAGNKGCQLMTAIMKTLDMQERVRLSKVCKTWAMIGRDRSVWRTVKLRNTNITNWSLLLREMVRYCTVELDMMGGIIKNPRMLKGGDWGELKSLRILRTDAREAEIIESIIKGMPQLQEMRTTCTSPALNLANIEKMIGLRVLRIRMLDAKARIVSLSPLQNLFCLNELGLRGITNMDVLDLLQLKDLPHLETLVLGSCRGMEVISFGAEFLPSLKRLRRLRLENHHSSSSFIIKEIMDGIAAGGSVQRLELINVNIDAELSRQLSECKSLHELLLMPDFHNNSAYVVHYIMQAINENSEQLSVFCLGITNELLRVTRALAMIKDKDIIPVVLPIPGVPDNDTLNESECGIGYLPVDRLESILHHMMPQAWLTVSKVSQLETINMKFWPAPARKDKVGCFSRN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01324107; iTF_01322641; iTF_01326390;
90% Identity: iTF_01324107;
80% Identity: -