Slat014742.1
Basic Information
- Gene Symbol
- lrrfip2
- Assembly
- GCA_037075145.1
- Location
- JBAMCM010000479.1:1726018-1731014[-]
Transcription Factor Domain
- TF Family
- LRRFIP
- Domain
- LRRFIP domain
- PFAM
- PF09738
- TF Group
- Unclassified Structure
- Description
- LRRFIP1 is a transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'- AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA [1]. LRRFIP2 may function as activator of the canonical Wnt signalling pathway, in association with DVL3, upstream of CTNNB1/beta-catenin [2].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 1e-116 2.1e-112 375.5 28.1 1 299 30 335 30 336 0.98 2 2 0.084 1.7e+03 -1.8 3.4 218 240 362 384 338 409 0.46
Sequence Information
- Coding Sequence
- ATGGATTGCTCGAGCGCCACCGGTCGACGGCGAAATAACACACGCGTCAATGCCGAGGATAATGCTCTGGATCAGATCACAAAAGAGGCGGAAGCCCGTTTGGCTGCACGTCGTCAGGCCCGAGCTGAGGCCCGTGAGATACGCATGCGTGAGCTGGAGAGGCAGCAGAAGGAGCAGGAGCAGAATGCCGATCGTGTTTTTGATATGCAAAATTCTGGCAGTCCCAGTGTCTTGATCAATGATACGAtatcctcctcctcctcctcatcgAATACCAACACAGCCACGGCACACCCCGCCCGTCTTGTCTATAGCAATTTAATGAATGTCACACGAGCCACTGCCTCCAGGCGCAGCAGCGAGGACTCTCTCGAAGAGGAGGGCCGGAGTATGCGTGATATTAAGCATGATCTAAAGACAGTGGAAGAGCGCTTCCGGAAGGCAATGATCCAGAATGCCCAGCTGGATAATGATCGCGCCTCACAGACATATGAGGTGAAGCTGCTCAAAGACAAACTGGAAACAATGGAAGAGTCCTTCGCCCAGCTCAAACGTGAATTCAAAGAGAAATCTCGTGATTGCAATGCCCTCAAGCGTAATCTGGATCGCACCAATTTAGAATTAAAACTTGTCCAAGGCCAATTAAATGAGCGTGACGCCCTAATTGCCGAACAGGGCATGGTGATTGTGTCCATTGAGAATGCCGATGGCAGTGATGCCAAACGTGCTCTAGTCAGTGTCGATAATGCCAATGTCTTGGCCTCCGTTCAGGGATCGCTAGATGTAAGACTCAAGAAATTCAGCGAGGAGAAGCAACAGCTTCAGGCCGAAGTTCAGAAATTAAGTGAACAGCTAGAAACATTTAAGAGTGAAGGCAAAGTGGGTCGGGGTTCTTCATTGAACGGACCCCTCGGCTATGACGACGACTACGAAGCTCAAAGAGGAGCGAATAAGATCATATCAGACTTTAAATATAAACTTCAAAAGGCTGAACAGGAAATCGCGAGTCTGCAGGCGAGCTTAGCACGTTCCGAGACTCAGGTGATCCGTTACAAGAGCACAGCAGAGGCAGCCGAAAAGGCCGAAGCAGAACTGAAAGTCGAAAGGCGTAAATTGCAGCGTGAGCATCGTGAGACATTGGAGCGTTTGGAGGAGGCGGAGACGGCAAATAATCATTTATTGAAACGTttggataaattaaaaaatgcaaaaagcgccattttaaaagatttatga
- Protein Sequence
- MDCSSATGRRRNNTRVNAEDNALDQITKEAEARLAARRQARAEAREIRMRELERQQKEQEQNADRVFDMQNSGSPSVLINDTISSSSSSSNTNTATAHPARLVYSNLMNVTRATASRRSSEDSLEEEGRSMRDIKHDLKTVEERFRKAMIQNAQLDNDRASQTYEVKLLKDKLETMEESFAQLKREFKEKSRDCNALKRNLDRTNLELKLVQGQLNERDALIAEQGMVIVSIENADGSDAKRALVSVDNANVLASVQGSLDVRLKKFSEEKQQLQAEVQKLSEQLETFKSEGKVGRGSSLNGPLGYDDDYEAQRGANKIISDFKYKLQKAEQEIASLQASLARSETQVIRYKSTAEAAEKAEAELKVERRKLQREHRETLERLEEAETANNHLLKRLDKLKNAKSAILKDL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00336724;
- 90% Identity
- -
- 80% Identity
- -