Rpad010442.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Rhopalosiphum padi
Gene Symbol
egg
Assembly
None
Location
scf7180000008446.652723:414997-419275[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 4.4e-10 1.3e-06 28.5 0.0 5 71 605 665 601 669 0.84

Sequence Information

Coding Sequence
ATGGCTTCATCAAGTAAAAGTTTGGGACCATATAAAATCAGTCCTGAAGAATTAGAGGAACAAAGGCGCCAACTTAGATGCATTAACAGGCGATGTAAATATGGTGCTACTTTAGTTGAAGCGGTGAAAATGGCATGCTCTTACTATGATGTTGATTACAAGCCGGGCAGAGAAGTTTGCTTAAAGTGTCTTACTAAATGTCTTAAACATTATAAATATCTCGAAGGAAAATGGAAGGAAGGAAAATGTGTTATGGACTCCAATTTTCCAAGTTATGATTCATACTTAATTATTGATGATTCATCATCATGTGAAAGTTCTGATGATTATGATGATGAGGAAGAGCCAAGACCTGGTACTTCTAGGGATGGTTTACTTCCTGACAAAGATGTTAAAAATGCTATTGATAGTGCAGTTTTACATTATTTTGATAAAAACAAATATCTCATTGATCATCAAGTTAAAAAATGTGATGAGTTTATGACTCGTGGGATAGAGAAATGTTTGATTGATGCTGAACACATTGAGACACTTGCTTCGGAGTTAGAAAATGAAATGAATTCATTAAGAAATGAATTATATAATCCATATCAACCAATTATAACTTCCTTAGATCCTGTAGACATAAATGATTTGGAGGAGAATACAGAAGAGGAAAATGAAAACTTCATAACATCTAATGAAGATCAGTTACCTATAGAAGGAGTCATTACTCCTAAAGAAGCCAAAAGACTTAAACTAGATAAATCTATAGATAAGGAAGATATTATTACTATTAATAGAACTGTTTGTCCTATACCAGCTAATCTACCTATGGAAGGGCCTTTAGAATATCCTCCTCTTGAAAGTGGACAAACTGTATATGCAATGAAGTCAACTTTAATACAACCATGGTATAGGTGTAAAATCAAAACATTAATTAATATTGATTATGTACATGTCAAATTTGAAAACGATGAAAAATTAGTGACAACAAAAGAAATTGCATTCTGTACACTGAATCCAGTAAGATTTCCTGTAGGTTGCAGAGTAATCGCTAAATATACAGATTCTAATTATCGACATGTTGATGAATTTTATGCTGGTGTAGTAGCTGAACCCCCAAAAATGCTTAATGAATTTCGATACTTGATTTTTTTTGATGATGGTTATGTTCAATATCGACAACATCAAGATATCCGTTTAATTGCACGTAGATCAAATCAAGTATGGAATGATGTATACTTGGATTCAAAAGAATTTATAAAAAGTTATTTAGAAAAGTATCCTGAACGTCAAATGGTTAAGTTGACTAATCAACATTCAGTACGTGCAGAATATAAAAATCAGTGGCAGATGGCAAAAGTGCTTGAAGTTGATTCATCTTTGGTCAAATTATATTTTCCCGATTTCAAACTTAGTGAATGGATCTATCGTGGTTCTTCACGTTTATATAATATTTTTGAAAAACAAACCAAGTCTGAGAGAGGCATTCGATTAAGGCAATCTGGACTAGCTTATTTAAATAAACCATTTGTGGAATTTACTAGTGTAGAAGAAGAACCCTGCCGTAATTTAGCTAAAATTATTGGTGTAGCTCGTAAAAGTACCAGCAAATCAACAGCACAAGGAGATGGAACTATAGGTGATGGAACTATAGGTGATGGAACTAATTTTATTACTAAAAGTATTAAAAATAAATCTAATTTTTCAAAGATTATTGATATAATATTGCCTAAGAACGTTCCCAATCCATTGAAATATACCAAACACAAATGTAATCCTTTATGTATTGAGTGGACAGCATATAGCTATGAAAGAACAAGACAAATCAGTATGTTAACTATTCCTTTACATTTTGGTTTTGTTAGGTATCTAACATTATTTAATAACTCTCAAAAATGTATCCTATACAGAACTCCGTGTGGTGTAACTATTCGAAACATGAAACAGATGCTGGAATATCTTATTGTTACCAAAAGCAAAATGACTATTGACCAGTTCGATTTTAATAGTTGGGTCAAACCATTTTCAGAATTTAAAATCATAAAATCCGTGCAATATTTAAGAGATATATCAGAGGGTAAGGAATTTAGAGGCATAACATGTGTGAATACTATTGACAGTACATTACCACCAAAAATGGATTATATGACTACTAGACAAGCGATGCCAGGTGTTCACATAAATGTAGAGAGTGATTTCTTATGTGGTTGTGACTGCACTGACGACTGCCAAGATAAATCAAAATGTGCCTGTTGGCAGATGACTATCGACGGACAAAAGATTTTACCTAATCTCTACAAAGACCCTAATATTGGTTACACTCATCGGAGATTGCCAGAACGAGTTCTAACTGGTATTTATGAATGCAATAAAACATGTAAATGTTCTAGTTCATGTTTAAATCGTGTTGTACAGAACCCATTGTCACAAAAACTACAATTATTCATGACGGAGAAAAAAGGATGGGGTGTAAGATGTTTAAACGATATACCTCAAGGAAGTTTTATATGCATTTATGTTGGTTATTTATTGACTGAAACTGATGCTAATGAAGGTGGCAAAAATTATGGCGATGAATATTTAGCAGAGTTAGATTATATTGAAGTTGTTGAAAAAATAAAAGAAGACTATGAAAGTGATGTACCTTTCAGTGACCATGAGAATGATTCCGAGAAGAATCAATCCGAATCGTCTGATGAACAATATCCTTCTACATCTGATGGCAAACGAACTGAAATGACACTAAGGTTGCGCAAACGCAAGAAATGTAAAACTAAAAAAGATGGTAAACATGTGCATGTTTCGTCCAAATTAAATGCGCGTGATATGAAAAACAACCCTGTACCTACAAAATCAATGCGTGAATATTTTGGAAACAACGAGAGTGTATATATCATGGATGCAAAAACTAGTGGCAACATTGGACGTTATTTAAATCATTCATGTTCTCCTAACACATTTGTCCAAAATGTATTTGTGGATACGCATGACTTACGATTCCCATGGGTATCGTTTTTTGCACTCCATTACATTCAAGCTGGTACAGAACTAACTTGGGATTATAGCTATGATATAGGAAGTGTTCCAGGAAAGAAGATGAAATGTCATTGTGAGTCAGTTTACTGTAGAGGGAGATTACTTTAA
Protein Sequence
MASSSKSLGPYKISPEELEEQRRQLRCINRRCKYGATLVEAVKMACSYYDVDYKPGREVCLKCLTKCLKHYKYLEGKWKEGKCVMDSNFPSYDSYLIIDDSSSCESSDDYDDEEEPRPGTSRDGLLPDKDVKNAIDSAVLHYFDKNKYLIDHQVKKCDEFMTRGIEKCLIDAEHIETLASELENEMNSLRNELYNPYQPIITSLDPVDINDLEENTEEENENFITSNEDQLPIEGVITPKEAKRLKLDKSIDKEDIITINRTVCPIPANLPMEGPLEYPPLESGQTVYAMKSTLIQPWYRCKIKTLINIDYVHVKFENDEKLVTTKEIAFCTLNPVRFPVGCRVIAKYTDSNYRHVDEFYAGVVAEPPKMLNEFRYLIFFDDGYVQYRQHQDIRLIARRSNQVWNDVYLDSKEFIKSYLEKYPERQMVKLTNQHSVRAEYKNQWQMAKVLEVDSSLVKLYFPDFKLSEWIYRGSSRLYNIFEKQTKSERGIRLRQSGLAYLNKPFVEFTSVEEEPCRNLAKIIGVARKSTSKSTAQGDGTIGDGTIGDGTNFITKSIKNKSNFSKIIDIILPKNVPNPLKYTKHKCNPLCIEWTAYSYERTRQISMLTIPLHFGFVRYLTLFNNSQKCILYRTPCGVTIRNMKQMLEYLIVTKSKMTIDQFDFNSWVKPFSEFKIIKSVQYLRDISEGKEFRGITCVNTIDSTLPPKMDYMTTRQAMPGVHINVESDFLCGCDCTDDCQDKSKCACWQMTIDGQKILPNLYKDPNIGYTHRRLPERVLTGIYECNKTCKCSSSCLNRVVQNPLSQKLQLFMTEKKGWGVRCLNDIPQGSFICIYVGYLLTETDANEGGKNYGDEYLAELDYIEVVEKIKEDYESDVPFSDHENDSEKNQSESSDEQYPSTSDGKRTEMTLRLRKRKKCKTKKDGKHVHVSSKLNARDMKNNPVPTKSMREYFGNNESVYIMDAKTSGNIGRYLNHSCSPNTFVQNVFVDTHDLRFPWVSFFALHYIQAGTELTWDYSYDIGSVPGKKMKCHCESVYCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01304193; iTF_01328636; iTF_00973047; iTF_01304859; iTF_00136128; iTF_00135323; iTF_00134272;
90% Identity
iTF_01304193;
80% Identity
-