Basic Information

Insect: Rhopalosiphum maidis
Gene Symbol: zfh1
Assembly: GCA_003676215.3
Location: NC:47271308-47279643[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 24 4.9e-06 0.00035 20.3 1.1 1 23 107 129 107 129 0.97

2 24 3.1e-05 0.0022 17.8 2.0 2 23 139 161 138 161 0.97

3 24 0.018 1.3 9.1 2.2 1 23 165 186 165 186 0.98

4 24 0.009 0.64 10.0 5.1 1 23 215 237 215 237 0.99

5 24 0.37 26 4.9 0.4 2 23 243 264 242 264 0.90

6 24 0.45 32 4.7 3.9 1 20 269 288 269 290 0.91

7 24 0.0049 0.35 10.9 0.9 2 21 312 331 311 336 0.92

8 24 1.9e-05 0.0013 18.4 0.8 1 23 337 359 337 359 0.98

9 24 0.045 3.2 7.8 2.1 1 23 708 730 704 730 0.88

10 24 6.1e-05 0.0043 16.8 2.6 1 23 801 824 801 824 0.97

11 24 0.19 14 5.8 3.9 1 23 830 852 830 852 0.96

12 24 0.052 3.7 7.6 6.6 2 23 905 927 905 927 0.95

13 24 1.8e-05 0.0013 18.5 1.2 3 23 981 1001 979 1001 0.97

14 24 0.0019 0.14 12.1 2.3 1 23 1007 1029 1007 1029 0.98

15 24 6.7e-06 0.00048 19.9 1.2 1 23 1081 1103 1081 1103 0.98

16 24 0.0041 0.29 11.1 1.1 1 23 1109 1131 1109 1131 0.97

17 24 0.0029 0.21 11.6 1.0 2 21 1163 1182 1162 1183 0.94

18 24 3.6e-05 0.0026 17.6 1.9 1 23 1213 1236 1213 1236 0.97

19 24 3e-05 0.0021 17.8 0.1 2 23 1280 1302 1279 1302 0.95

20 24 2.5e-05 0.0018 18.1 4.8 2 23 1310 1332 1309 1332 0.97

21 24 0.00071 0.051 13.5 0.9 1 23 1364 1386 1364 1386 0.97

22 24 8.1e-05 0.0058 16.5 0.3 1 23 1391 1414 1391 1414 0.95

23 24 0.0019 0.14 12.1 0.7 2 23 1446 1467 1446 1467 0.98

24 24 6.3e-06 0.00045 19.9 2.7 1 22 1473 1494 1473 1494 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	24	4.9e-06	0.00035	20.3	1.1	1	23	107	129	107	129	0.97
2	24	3.1e-05	0.0022	17.8	2.0	2	23	139	161	138	161	0.97
3	24	0.018	1.3	9.1	2.2	1	23	165	186	165	186	0.98
4	24	0.009	0.64	10.0	5.1	1	23	215	237	215	237	0.99
5	24	0.37	26	4.9	0.4	2	23	243	264	242	264	0.90
6	24	0.45	32	4.7	3.9	1	20	269	288	269	290	0.91
7	24	0.0049	0.35	10.9	0.9	2	21	312	331	311	336	0.92
8	24	1.9e-05	0.0013	18.4	0.8	1	23	337	359	337	359	0.98
9	24	0.045	3.2	7.8	2.1	1	23	708	730	704	730	0.88
10	24	6.1e-05	0.0043	16.8	2.6	1	23	801	824	801	824	0.97
11	24	0.19	14	5.8	3.9	1	23	830	852	830	852	0.96
12	24	0.052	3.7	7.6	6.6	2	23	905	927	905	927	0.95
13	24	1.8e-05	0.0013	18.5	1.2	3	23	981	1001	979	1001	0.97
14	24	0.0019	0.14	12.1	2.3	1	23	1007	1029	1007	1029	0.98
15	24	6.7e-06	0.00048	19.9	1.2	1	23	1081	1103	1081	1103	0.98
16	24	0.0041	0.29	11.1	1.1	1	23	1109	1131	1109	1131	0.97
17	24	0.0029	0.21	11.6	1.0	2	21	1163	1182	1162	1183	0.94
18	24	3.6e-05	0.0026	17.6	1.9	1	23	1213	1236	1213	1236	0.97
19	24	3e-05	0.0021	17.8	0.1	2	23	1280	1302	1279	1302	0.95
20	24	2.5e-05	0.0018	18.1	4.8	2	23	1310	1332	1309	1332	0.97
21	24	0.00071	0.051	13.5	0.9	1	23	1364	1386	1364	1386	0.97
22	24	8.1e-05	0.0058	16.5	0.3	1	23	1391	1414	1391	1414	0.95
23	24	0.0019	0.14	12.1	0.7	2	23	1446	1467	1446	1467	0.98
24	24	6.3e-06	0.00045	19.9	2.7	1	22	1473	1494	1473	1494	0.96

Sequence Information

Coding Sequence: ATGACTCCAATGAAAGATTACATTAAAGTTGAGGTTACTGGTGATGCTGATGCTGTTAccagtgaATTATATGTCGAAAACACTATTGAAAATCCTGCATGGTATACAGTCGAAGATAATCATGTATCTTTGATATCTGAAAATGTTGAGAAAGTTATAAAAGTTGAAACTGATATGTTGGATGATTGTATGTGGGAAAGTAGGATCGAAATTTCTAAAGATGTTGCCAACCAAAATAACGTGGAGTTATCCTTGGAAACTCAGaaTATCCCAgttgataatattgaaatgaatCCGGAAAGTAcaagtcataaaatattttactgtaatatttgTGGAAAAAGCTTtgctttaaattatcttttgaAAAATCACACAAAAGAACACAAAAGacaagtacattttaaaattaataaatgtaaatattgtggAGAAcggtttaagttaaaatttggttTGAATAGAcacattcaaaaatatcacAATCATATGTATGAATGCAAGTTTTGCaaacttatttttgaaaaaagtatgtataatgAACACATGAAAAGCCACGAAAAAAATGAAGCTAGAATTGATACTATtcctaatataaaattgcgCAAATTAAATGGTGTTTggaaaagtaaaacaaatgtatttaaatgtaacattTGTTTCCAAAAATGTCATAGTGAAAAGAATTTAGTAGAACATATGGAAACtcataacaattttcaaacaCAGTGTAATGATTGCTTAAAGTACATATCAGTTTCTGAATTGAATAATCATATgcaacaaatacataataaacatttatttaaatgtcagAAGTGTAATCTACAGTTTGAAAAACAACAGCATTTAAACTGTCATTTAAttcattgtttaaaaagttCTTCTACCAAATGGAATAAGGTTCGTGGTAAATGCAAGGTGAATTCAACAACTTGCTCTGCTTGtggaattgtttttaataattctttatcACTGAAAAATCATATGACTATTGGCTGTAAGCATTACACTTGTAAATATTGTGGGCAATTTTTTAGTTCAAGGATTTTATGGCTAAGACATATGGATGTTCACGAAAAAGATGAACAGTGTGTAATGTTAACAGTAAATACCGATAAAACAACTACAATTAAAGAATATGATCAAACTAAGGTTGTGAATGGTTCTTCTTGCAATACAAATGAAGGGCAATTATTATCTAGAAATGTTATTGGAAAAAATAGTTCAGATCAAACCAATTTAGTGATCAGCAATGACCACATTGCACCACatttaatggtaaataatattaatttgaatattaataaagaaaaaagatCATGTAAGAAAGAAGCAGTGAATAGTAATGAGTCAATCACACTAAATATATcacaaaatttaatgatagatGAGaacaatactaatttaaagcaaaataaaatcttagtaaatatcaaaaaaagaaATGGTTCAGGTCAAATAGATTTAATGAACAGCAATGCAACAATTGTATCAACTGCTTCAAATAATTCAATGGCAAATGAttgtcatattaaaaatataaagcaaGAAAGATGTTTTAATGCAAATGCcaaagacaaaaatatttcacatcAAATGATCAACAATCAACCAACTGTATCGGCTGTTCCACATAATTCAATTGCAAACAATTgccttgttttaaatattaagcaaGAAAAAGACTTATGTACAACTACTGAAGAAACAAATAGTTCAGATCAAATAAATTCAGTTAACAGTAATGAATCAATTTCTACTGTTTCACATActtcaatatcaaataatgtCTTAAATATTAAGCAAGAAAAACACATGAGTACAAATGACAGAGGAAGAACAAGTTctgataatattgatttagtgAATAGTAATGATTCAATGGCATATCAAAACCCTATTAATATAGCTAATAGTCATATTGCATCTACCATTAGAGAAACaccttatttttgtattagaaAATTGcctaatattaaaagtgtattttacaatgataataatgaacagACATCGCAAaatgatgttatatttatatgtagaaTTTGTAGAAAATCTCCAGCTACAGATATACATTCATTTGCATTACACATGAGTGATCACAGTGAATGTAACATGCATGAATGTATTGTTTGTGATAAGACATTTACCACTGTACTTCTTTGGACAAACCATATGACTTATCATCAACAGcaattagatttaaatgtaTCAGCAGTGCAATATAATCTTATAGGAACTGATCCTAATACATTGGCGGGCCCAATTAATTCTGGAAATACGGAACCTCAAGTTTGTACAACTTCAAGAAATAGGAAATTTAAGACATCTTCATCgaatgattcatatttagatataataagcTTGAATAATAgtgccaataaaataaaaaatcaatatgacTGTAGTACatgtaaaaaagtatttcCTTCCAAGGTTACATTAAAAGTTCATCATCAAACTAATCATAATAAAGCACAATCATTTTTCTGTAGGTATTGTGATAGAATATTTTCTGGAAGGGGTCAATGTACAAATCATGAAAAATCacacattggcttaaatgaattagttttacaaaataatgaggATAATAATCCAGAATCAATTGTAAACCAAAACAACATAagcatagaaaataataacattgattCTGAGACAAGgtcaataaaacataaaaataaaataaaattatcgactagaaaaaattattgtaatttatgtagAAGAAAATTTACAAAGCGCTGTTATTTCACAAATCATAtgcaattaaaacataatataaagacaAACTCAACAAAACAACTTACATCAATAGATTGCAGAAAGCCAATTGTTCTATCTAAAAACATAGAGttgactaataaatataaaaacaaattatcagtTCCAGTAGATAGAGATTTGAATAATCAAAATGAAAAGAAATCAACATTTTGTaccatttgtaataaaaattttgcaCATCTTGGTGCCTTAACCAATCATATGAATATTCATTCTgatcataaactatataaatgtcaatattgTTCTAGAAAATTTAGAAGAGAAGGTCCTTATATAATGCACGAGAAAAAGCATGTATTaaacaatgaaattaaaagtGCTCCCAATCAAAACAggaataatataacagttgAAGTTAATGAAAATTGTAACGATTTTCATTTGGTTCATAATCCAGTGGATGGAAATTCAAATggtacaaattttattaactcaAAACATTTATGGTTTACCTGTGATGTGTGTGAGAAAAAATTTTCTACTCCATTCTTATTGAATATACACCGAAAGTCACATCCTGATGTTGTGCCATACATATGTAAGATTTGTAATAGATCATACTCATTGAAATTTCGATGGAATTGGCATTTAAAAGAACATTACGTAAGACATTATAGTAAACAACATActaataatcttaaatcaAACATTGGTAAACAAAAGATTGGATCTATACATCATCAAGATAAAATGAAATGTCGATAttgtaaaaaagaatataactCAATATCTCAGTGGAAAAAACATATGACAATGAGCAAGGAATGTCGTCGCCATTGTAAAAGTAATCTTCCAGAATTTACATCAAATCAAGCTTCAAAGAAATCTACTAAATCTTGtcgatttaaatgtaatatttgtcAGAAAACATATAGTACCTCTTATAATCGATcagtacatataaaaaatgttcacaatAAGTTAGATAcaacagttttaaatattcataataataccagttttcaaaaagaaaaaccaATAGAAATAATTCAACAGAAACCAGTGATTAAGAAAGGAAATAGaagtaattacattaatagcactaaatgtaaattatgtgGTAAAGTATATAGTAGTGCAGCTAATTTAGGTCGCCACGTATCTATAATTCACACAAATAGTTATAAACCTATGACCTGTAATGTTTGTGGAAAGAcatttaaacacaaattttCTTATAgagaacatttaaaaactaaacacaaaaaattatttaaaaattatgaagaaataaactgtaaaaataaaagaaccaACAGGAAAGTTATACCAATGAATAAAAAAGGAATTACGAAATACTTTtgcaaaatttgtaaaattaagtttgcagacaatattacattacaagAACACTCAAAGATGCATgtagtaaatatgtataagtgtAAAGACTGTGGTCAACAATTTGAGACAAATGTTACTCTGGGtaatcatattttagaaaaccaTAGTGCTAATATttctacatttaataaaaataaacatgttgAGAATTATGAGAGTCAAAATGCGTctcaaaaagtaattaataataaccctGCTCAATGTAAAGTTTGTTTGAAAATCTTAAAAGACCCTGGATATTTACATGAACACATGAGATTACACACAGGTGTCAAACCATTCAAATGTGATAATTGTAACAAGGCTTTCAGATTTAAATCAAACTTAAGAATGCATCAGAAGAAAAATCTGCCATGTTatattccataa
Protein Sequence: MTPMKDYIKVEVTGDADAVTSELYVENTIENPAWYTVEDNHVSLISENVEKVIKVETDMLDDCMWESRIEISKDVANQNNVELSLETQNIPVDNIEMNPESTSHKIFYCNICGKSFALNYLLKNHTKEHKRQVHFKINKCKYCGERFKLKFGLNRHIQKYHNHMYECKFCKLIFEKSMYNEHMKSHEKNEARIDTIPNIKLRKLNGVWKSKTNVFKCNICFQKCHSEKNLVEHMETHNNFQTQCNDCLKYISVSELNNHMQQIHNKHLFKCQKCNLQFEKQQHLNCHLIHCLKSSSTKWNKVRGKCKVNSTTCSACGIVFNNSLSLKNHMTIGCKHYTCKYCGQFFSSRILWLRHMDVHEKDEQCVMLTVNTDKTTTIKEYDQTKVVNGSSCNTNEGQLLSRNVIGKNSSDQTNLVISNDHIAPHLMVNNINLNINKEKRSCKKEAVNSNESITLNISQNLMIDENNTNLKQNKILVNIKKRNGSGQIDLMNSNATIVSTASNNSMANDCHIKNIKQERCFNANAKDKNISHQMINNQPTVSAVPHNSIANNCLVLNIKQEKDLCTTTEETNSSDQINSVNSNESISTVSHTSISNNVLNIKQEKHMSTNDRGRTSSDNIDLVNSNDSMAYQNPINIANSHIASTIRETPYFCIRKLPNIKSVFYNDNNEQTSQNDVIFICRICRKSPATDIHSFALHMSDHSECNMHECIVCDKTFTTVLLWTNHMTYHQQQLDLNVSAVQYNLIGTDPNTLAGPINSGNTEPQVCTTSRNRKFKTSSSNDSYLDIISLNNSANKIKNQYDCSTCKKVFPSKVTLKVHHQTNHNKAQSFFCRYCDRIFSGRGQCTNHEKSHIGLNELVLQNNEDNNPESIVNQNNISIENNNIDSETRSIKHKNKIKLSTRKNYCNLCRRKFTKRCYFTNHMQLKHNIKTNSTKQLTSIDCRKPIVLSKNIELTNKYKNKLSVPVDRDLNNQNEKKSTFCTICNKNFAHLGALTNHMNIHSDHKLYKCQYCSRKFRREGPYIMHEKKHVLNNEIKSAPNQNRNNITVEVNENCNDFHLVHNPVDGNSNGTNFINSKHLWFTCDVCEKKFSTPFLLNIHRKSHPDVVPYICKICNRSYSLKFRWNWHLKEHYVRHYSKQHTNNLKSNIGKQKIGSIHHQDKMKCRYCKKEYNSISQWKKHMTMSKECRRHCKSNLPEFTSNQASKKSTKSCRFKCNICQKTYSTSYNRSVHIKNVHNKLDTTVLNIHNNTSFQKEKPIEIIQQKPVIKKGNRSNYINSTKCKLCGKVYSSAANLGRHVSIIHTNSYKPMTCNVCGKTFKHKFSYREHLKTKHKKLFKNYEEINCKNKRTNRKVIPMNKKGITKYFCKICKIKFADNITLQEHSKMHVVNMYKCKDCGQQFETNVTLGNHILENHSANISTFNKNKHVENYESQNASQKVINNNPAQCKVCLKILKDPGYLHEHMRLHTGVKPFKCDNCNKAFRFKSNLRMHQKKNLPCYIP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01305846;
90% Identity: iTF_01329188;
80% Identity: -