Rfor018344.1
Basic Information
- Insect
- Rhodophaea formosa
- Gene Symbol
- MBD3
- Assembly
- GCA_963082605.1
- Location
- OY720219.1:12577433-12587659[-]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 5.2e-28 2.9e-24 85.3 0.1 1 72 5 71 5 75 0.95 2 2 0.0018 10 6.7 0.0 29 73 93 149 78 152 0.80
Sequence Information
- Coding Sequence
- ATGAATATATCTATTGAAAAGAAAAGATCAGATTGTTCAGCACTTCCCAAAGGATGGCAAAGAGAAGAAGTGTTGAGGAAAACTGGACTAACAGCTGGAAAAGTTGATGTTTACTATTACAGCCCTACAGGTAAAAAGTTTCGCAGTAAGCCCGAGCTAGTTCGTTATCTCGGTGATAGTATGGACCTGTCGTGTTTTGACTTCCAACAGGGTCAAATAAACACAATGTTGCTGTGCAAGGCCAAGAAAGCACGGGCTCAGTTCGATTACAGggGTGTCCGCTCTGACGCGTCGCTCGTGCCACCTATCCGCCAAACGGCGTCCATTTTCAAGCAGCCAGTTACTGTGTACAAGACCCAGGAAAGCAAGGTGAAGACCGACCAGAAACATGAGCGCACGGGGGACAAGCAGGAAAAGCCGAAGCAGTTGTTTTGGGAAAAGAGACTAGAGGGCCTCACAGCTTGTGATGCAAATGGCGTGATCGGAACTACGTCTCTGCCGAAATACATCAAGCCTTTGGGGCCATACACTTCTGACGCAACCACCATTCAGTCCCTGGCGACAGCGTTACACGTCTCATCCCAGCAAATCACGGgcCAAACAGGATCAAAACAAGCAATAATGGAGAACCCCGGAGTTTTTTTAAACCCTGAGCAGCCGCTGATAGCCGCCGTCACCATCACCAAGGAGGACGTGCGCCGCCAGGAGGAGCGCGTGAAGCGCGCGCGCCTGCGCTTGCAGCAGTACGCCGGCGACGGGGACTCTGGGGGCCCCGCCGCCGCGCCTGCCGAACCTGAGGCCGAGCCCGTGCCCGCGCCCGAGCTTCAGCCTGAGCCGCAGCCCGAGCCGCCCGAGCTCCCCGACTCCTCCATGATGCCAGACTCCACAGAAGATTCGCCCTTACTGCCTGTCGACGTTAAGTGCAACCTCGACCTcgataatgataatgaatgcGTGCTAGAATCTCTTTAA
- Protein Sequence
- MNISIEKKRSDCSALPKGWQREEVLRKTGLTAGKVDVYYYSPTGKKFRSKPELVRYLGDSMDLSCFDFQQGQINTMLLCKAKKARAQFDYRGVRSDASLVPPIRQTASIFKQPVTVYKTQESKVKTDQKHERTGDKQEKPKQLFWEKRLEGLTACDANGVIGTTSLPKYIKPLGPYTSDATTIQSLATALHVSSQQITGQTGSKQAIMENPGVFLNPEQPLIAAVTITKEDVRRQEERVKRARLRLQQYAGDGDSGGPAAAPAEPEAEPVPAPELQPEPQPEPPELPDSSMMPDSTEDSPLLPVDVKCNLDLDNDNECVLESL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00720311;
- 90% Identity
- iTF_00013043;
- 80% Identity
- -