Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 2.7 4.7e+03 -1.2 0.0 22 44 123 145 113 153 0.74

2 6 0.027 47 5.2 0.0 20 45 149 174 146 182 0.83

3 6 0.21 3.6e+02 2.4 0.1 26 45 183 202 178 205 0.88

4 6 8.3e-07 0.0014 19.7 0.1 21 52 206 237 201 238 0.88

5 6 0.58 1e+03 0.9 0.1 21 31 234 244 232 258 0.76

6 6 0.0046 7.9 7.7 0.0 19 44 260 285 250 292 0.82

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	2.7	4.7e+03	-1.2	0.0	22	44	123	145	113	153	0.74
2	6	0.027	47	5.2	0.0	20	45	149	174	146	182	0.83
3	6	0.21	3.6e+02	2.4	0.1	26	45	183	202	178	205	0.88
4	6	8.3e-07	0.0014	19.7	0.1	21	52	206	237	201	238	0.88
5	6	0.58	1e+03	0.9	0.1	21	31	234	244	232	258	0.76
6	6	0.0046	7.9	7.7	0.0	19	44	260	285	250	292	0.82

Coding Sequence: ATGGATGCAGTAGGAAATGAGAAGTTTCAAGATTTGGAATACCCAATTCAAGGTTTGCAATCACCAtggaatttaaatattaaaacagaGAAGGTGGACATAGAAATTAAGTCGGAagttttgcacacttcaattgACATTAAAGAGGAGACTTTTACACAAGAAGTCAAGTTGGATGAAGAAGAACCTAAACTAAAAAGATGCAAATTTGAATGTGATATAtgtaacttaaaattgaataatgaaGTCCAACTGGACGAGCATACAAAAATTCATTCCAGTCCAAAATTATTTGAGTGCATAATTTGTGGCTATAAATCTCCATACAAGCAATCATTACAACGCCATTCAAAAACACATACAGGTGAAAAATCATTCCAGTGTAACATTTGCGATTTTAAGTGTTCCCAAGAATCATATTTGAAACTTCACGTTATAACTCATAGCTCCGAGAAACCATTCAAGTGCGACCAGTGTTACTATAAGTCTTCTCGAAGAGATTATCTGAAAAAGCATCTAAAAACTCATATCGGTAATAAAGGAATGGTGTGTACAATTTGTGATCATACGTTTAAACGAAAACAAACACTGATTCGGCATCTGAGAACgcacactggcgagaaacctTACACGTGTGAAGTTTGTGTTGCAAACTTTTCACAATCGTCGCATTTAAAACGTCATTTACGAATGCACACCGGCGAAAAGCCGTGGACCTGTGAAGTTTGTGGATTTAAATGTTCAGAAAATGCACATTTGAAAGAACATCGTAAAAGTCACACCGGCGAAAAGCCCTTTACATGTGGTATATGCGACTTCAAATGTTCACGAAAGCAAAATTTAAACAGTCACTTCAAAACGCACAGTAAGGAAAAACAATCTACCCACAAGAAACTTGGTAGTACATGTGCAAtttga
Protein Sequence: MDAVGNEKFQDLEYPIQGLQSPWNLNIKTEKVDIEIKSEVLHTSIDIKEETFTQEVKLDEEEPKLKRCKFECDICNLKLNNEVQLDEHTKIHSSPKLFECIICGYKSPYKQSLQRHSKTHTGEKSFQCNICDFKCSQESYLKLHVITHSSEKPFKCDQCYYKSSRRDYLKKHLKTHIGNKGMVCTICDHTFKRKQTLIRHLRTHTGEKPYTCEVCVANFSQSSHLKRHLRMHTGEKPWTCEVCGFKCSENAHLKEHRKSHTGEKPFTCGICDFKCSRKQNLNSHFKTHSKEKQSTHKKLGSTCAI

Sequence clustering based on sequence similarity using MMseqs2