Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 1.1e-06 0.0019 19.3 0.3 9 48 45 85 39 91 0.82

2 6 0.17 2.9e+02 2.7 0.0 21 44 86 109 82 113 0.87

3 6 0.055 94 4.2 0.0 15 43 108 136 103 141 0.77

4 6 0.032 56 5.0 0.2 21 45 142 166 134 175 0.81

5 6 0.073 1.3e+02 3.8 0.1 26 44 175 193 171 202 0.86

6 6 0.055 96 4.2 0.2 27 51 204 229 200 231 0.77

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	1.1e-06	0.0019	19.3	0.3	9	48	45	85	39	91	0.82
2	6	0.17	2.9e+02	2.7	0.0	21	44	86	109	82	113	0.87
3	6	0.055	94	4.2	0.0	15	43	108	136	103	141	0.77
4	6	0.032	56	5.0	0.2	21	45	142	166	134	175	0.81
5	6	0.073	1.3e+02	3.8	0.1	26	44	175	193	171	202	0.86
6	6	0.055	96	4.2	0.2	27	51	204	229	200	231	0.77

Coding Sequence: ATGGCGAACACTAATCGAACACAGGAAGGTTTAAGTTTGGCTGGTACTAAAGAAGACGAAATCGAATCTGATAAACCGCAATGGTCTTTTCCAATAGAAGTCGAGAATTCTGGACAAAAGTTGAATGAAACCACACCTTCCACAAAACCACCAAGAATGCAGATCAAAATGGGACAAGAACCTTGCATATGCAAAATTTGTTTCATCACGATATCACATGCGGGTAACTTGAAGAGGCACATGCGATGCCATACGggcgaaaaaccatttataTGTTCAGTTTGTAATAGTAAATTTTCAGATAAATCCCATCTCAAAAAACACATGTCAACTCACACCGGCGAGAGACCATTTTCTTGTGATATTTGCGATTTCACTTCTGTAACAAGAGAAAACTTGAAAACGCACACCAAAACTCACACCGATGAGAAGCCATTTCAGTGCGAAATGTGCGACTACAAGTGCAGGCGAAAGGCTAATTTAGATCACCACATTAAAGCGCACCTGAAGATAAAGTTATTTGCATGTAAGCTTTGTAAGGCATCGTTTTTGCACAGCTCCAATTTGAAGAGCCATGTTTTAATCCATACTAAAATGAAGCATTATGATTGCTACGTTTGTAAGTATAAAGGTACCTCGGCTAAAAAGTTTAAACGGCATTTAGAATCCCGCGAACATTTCGACAAGGTAAAAATGATAACTGAAAGTTTGtga
Protein Sequence: MANTNRTQEGLSLAGTKEDEIESDKPQWSFPIEVENSGQKLNETTPSTKPPRMQIKMGQEPCICKICFITISHAGNLKRHMRCHTGEKPFICSVCNSKFSDKSHLKKHMSTHTGERPFSCDICDFTSVTRENLKTHTKTHTDEKPFQCEMCDYKCRRKANLDHHIKAHLKIKLFACKLCKASFLHSSNLKSHVLIHTKMKHYDCYVCKYKGTSAKKFKRHLESREHFDKVKMITESL

Sequence clustering based on sequence similarity using MMseqs2