Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 8.2e-06 0.014 16.5 0.0 20 47 95 122 84 127 0.85

2 7 0.99 1.7e+03 0.2 0.1 23 44 154 175 150 179 0.73

3 7 0.0039 6.8 7.9 0.3 21 43 180 202 177 206 0.90

4 7 0.0081 14 6.9 0.1 21 49 208 236 203 239 0.84

5 7 0.017 29 5.9 0.1 21 47 236 262 232 267 0.84

6 7 0.27 4.7e+02 2.0 0.1 21 44 264 287 261 290 0.69

7 7 0.13 2.3e+02 3.0 0.0 22 45 293 316 288 319 0.75

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	8.2e-06	0.014	16.5	0.0	20	47	95	122	84	127	0.85
2	7	0.99	1.7e+03	0.2	0.1	23	44	154	175	150	179	0.73
3	7	0.0039	6.8	7.9	0.3	21	43	180	202	177	206	0.90
4	7	0.0081	14	6.9	0.1	21	49	208	236	203	239	0.84
5	7	0.017	29	5.9	0.1	21	47	236	262	232	267	0.84
6	7	0.27	4.7e+02	2.0	0.1	21	44	264	287	261	290	0.69
7	7	0.13	2.3e+02	3.0	0.0	22	45	293	316	288	319	0.75

Coding Sequence: atggAAGAGTTACCAGATATGGAAAGCATCAAAATAGTTTCAGAAAATCCATGTAATTCAAGTTGCAGTTATGAACTTAAGATCGAAGAAGTGGAAGacgtaaaatttaattctgaagAATTGCATCATTCGATTGACATTAAAGAAGAGTGCGAAAAAGAACAATCAGGACAAGAAGTTAACAAATCACAAAAGTTAAACAGCCCAAATTTATTCGAATTTGTGACGTGTGAGAATCGAGTCACACGTACAGATGCGTTAAAACGACACTCAGGTTCAAACACTGATGAAAAACCATTCACATGCAACTTTTGTGATTATACATATCGGtataagggaaatttaaaaagacatttggAAATCCACGCCGGCGAAAAATTGTTTGCGTGTACTGCTTGTGACTACAAGTCGGAACATCGAGATCATTTTAGTGAACATTTGAAAATTCACGCTCGCCAGAAGCCATTTTCATGTTCcatttgcgactataaatcaGCTCAGAAGAGTCATATGAATGAACATCTGATGATCCATTCCGGCGAAAAGCCGTTTTCGTGCaatatttgtgactataaatgtgcgcAGAAAAGAAATTTGCAAATTCATCGaaaaactcatacaggggaaaaaccgttttcCTGCTGTATCTGCGACTATAAATTTCGGCATAAAGGGCACTTGAAAGCCCATTTAAGGATTCATTCCGGTGAGAAGCCGTTTGCGTGCcatatttgtgactataaggGTTTGCAAAGAAGAACGTTAAATGAACATTTGAAGACTCACAGTGGTGAAAAGCCCTTTgcttgtgatatttgtgactatcaAAGTGCTCGTAGAGATACCTTGAGATTACATATAAAAACGCACACCGGAGAGAAAGGGTTTACTTGTGGTATTTGTGATTCCAAATATACTCGTAAATCAAGgttaaaaactcatttaaatACCCATTCTAAATGA
Protein Sequence: MEELPDMESIKIVSENPCNSSCSYELKIEEVEDVKFNSEELHHSIDIKEECEKEQSGQEVNKSQKLNSPNLFEFVTCENRVTRTDALKRHSGSNTDEKPFTCNFCDYTYRYKGNLKRHLEIHAGEKLFACTACDYKSEHRDHFSEHLKIHARQKPFSCSICDYKSAQKSHMNEHLMIHSGEKPFSCNICDYKCAQKRNLQIHRKTHTGEKPFSCCICDYKFRHKGHLKAHLRIHSGEKPFACHICDYKGLQRRTLNEHLKTHSGEKPFACDICDYQSARRDTLRLHIKTHTGEKGFTCGICDSKYTRKSRLKTHLNTHSK

Sequence clustering based on sequence similarity using MMseqs2