Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.11 7.9e+02 0.6 0.1 26 37 127 138 116 150 0.73

2 5 0.082 6.1e+02 1.0 0.0 22 44 153 175 144 178 0.80

3 5 6e-05 0.45 11.0 0.1 22 46 181 205 174 208 0.89

4 5 2.3e-05 0.17 12.3 0.1 21 52 208 239 205 241 0.90

5 5 0.0046 34 5.0 0.0 22 48 237 263 234 267 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.11	7.9e+02	0.6	0.1	26	37	127	138	116	150	0.73
2	5	0.082	6.1e+02	1.0	0.0	22	44	153	175	144	178	0.80
3	5	6e-05	0.45	11.0	0.1	22	46	181	205	174	208	0.89
4	5	2.3e-05	0.17	12.3	0.1	21	52	208	239	205	241	0.90
5	5	0.0046	34	5.0	0.0	22	48	237	263	234	267	0.88

Coding Sequence: ATGGAAAGCGCCTGCGAGAGAGATTTTCACAGAAGTTTAGAGCCTGATGTGATCATTAAAGATGCCGCAAGCGACGAAGATAGTGAAGTTAACTTGAACAAGTCCAGTGATGGCTTTGATAGCCGCAGCTCCTATCTGTCTGAATTGCCCAAGGGCCCCTTGATGAGGTCAATCGGTCCCGACATATCTATAATTCCCATAAATCGCAAACCCCAAATCAAAATAAGACTGTTTAAAAAAGAATACTCTCCCGCCAAGGACGACACGAAAGTACAAAGCATCTCTCGATCTCCTCGAACAACAGTAAGACTGGTATCGAAAGACGAGGCGGAAAGCGCCGGCGACACTTACGCCCGTCGTAAATCCCTTCCATTAGAGAAATGTCCCGTATGTAAAAAGTTTTTCCGCAGAATGAAAACGCATTTGTTAAAACACGATGTCGCCAATCGCAATCCCGACGATCCTCTCACCTGTACTTTCTGCATGAAAGGTTTCAACACTCAAAGCAATCTTTTGATTCACATGAGAACGCATACTGGAGATAAACCTTATACTTGCGATATTTGTCAAAAAGGTTTTGCGCAATCTTGTAATTTGGTTAATCATATGCGGATTCATACTGGAGAAAGACCTTTTAAGTGTCCTCATTGCGAAAGAGCTTTCACTCAATCGGGTAATTTAAACAACCACATCCGGTTGCATACCGACGATAAACCGTTTAAGTGTCATTTTTGCGATAAAGCTTTCGTTCAATCAGGCAATCTCAATTCGCATATTAGAAACAATCATAAGATCGAGGTCGATGTAAGGGGTGAAGGGAACGACGCGGAATTGCCAGAGTTCAAATGCTAG
Protein Sequence: MESACERDFHRSLEPDVIIKDAASDEDSEVNLNKSSDGFDSRSSYLSELPKGPLMRSIGPDISIIPINRKPQIKIRLFKKEYSPAKDDTKVQSISRSPRTTVRLVSKDEAESAGDTYARRKSLPLEKCPVCKKFFRRMKTHLLKHDVANRNPDDPLTCTFCMKGFNTQSNLLIHMRTHTGDKPYTCDICQKGFAQSCNLVNHMRIHTGERPFKCPHCERAFTQSGNLNNHIRLHTDDKPFKCHFCDKAFVQSGNLNSHIRNNHKIEVDVRGEGNDAELPEFKC

Sequence clustering based on sequence similarity using MMseqs2