Pnig003062.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Pterostichus niger
Gene Symbol
zfh1
Assembly
GCA_947425015.1
Location
OX380341.1:6921300-6931126[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.044 6.2 9.0 1.8 2 23 52 74 51 74 0.95
2 9 2.8e-05 0.0039 19.1 0.9 1 23 104 126 104 126 0.95
3 9 4.2e-05 0.0059 18.5 1.8 2 23 133 154 132 154 0.97
4 9 7.1e-06 0.001 20.9 5.9 1 23 163 185 163 185 0.99
5 9 0.00013 0.018 16.9 0.9 1 21 191 211 191 212 0.95
6 9 0.023 3.3 9.9 2.6 1 19 459 477 459 477 0.97
7 9 1.4e-05 0.002 20.0 0.9 1 23 863 885 863 885 0.94
8 9 0.00021 0.03 16.3 10.0 1 23 891 913 891 913 0.98
9 9 0.0033 0.47 12.5 4.3 1 21 919 939 919 940 0.96

Sequence Information

Coding Sequence
ATGGTGGCACGTAGTGAGAGCATGTTCGGTTGCTACGACAGTTACAGTTACCGGCTTTGGAGTCTGGCCAACGTTTGGAGCACCTGTCACTTTCCCGCGTTAACAAACGGCGTGTCGAAGGACGGAGAAGAGGCGGCAAGCGCCGACTTCATCAAATGCCCGCAGTGCCAGAAGGGTTGCGGCAGCTTCCAGGCGTTAAAGGAACACATTGAGGTGTGTCACCCGCACGCCGTACCCGAGGAGGCTAGTCCTGCACCTCTACCACCTGCTGCAGCCTCTGCCGCAGCGTCGCCCCCACCTACAGGACCCTACGCCTGCTCGCAGTGCACCACATCCTTCTCCACTAAGGATCAGTTGGAGAAACACGAGCTTCTGCATTCGCCGAATGCGCAAGTGTCCTGTAAAGTTTGCCATAAAACATTTGCCAACGTTTACCGACTACAGAGGCACATGATCAGCCACGATGAAAGTGCCATCCTCCGAAAATTCAAATGTACAGAATGTGAAAAAGCATTTAAATTCAAACATCACTTAAAAGAACACATTCGAATTCACAGTGGTGAAAAACCATTCGAATGTGCGAACTGCGGGAAACGTTTCTCGCACTCTGGATCGTACTCAAGTCACATGACATCGAAAAAATGTTTAGTGATGAACCTGAAAATGGGACGAAATCGCGCAGCAAGCGGTGCCAACTCTTTGCTGGACAAGAGTCCATCACAAGCATCGCGAGGTCCCAAACGGCCGAGTGTCGCGTCCCTCAATAACAACATCACCACCAGCCCCAACCACAATTCGTACTTGCCGATCCTGCCCAAGTATAGTGAGGCAGCAGCAGCGGCGTTCCTATCCGTCATGGCTCCCCGGGATTCTGCCTACCCGCCACCCTCCTCTGCAGCCGCGTCATTGCATCCCTTCTACATGACACCCCCTGGACTGCATCTTGGTGCCGCCGCCCACCCCATCTCTCCGTACACGATGTCTGCGTCTCTGGGTCAACTCCTGGAGCAGCTGCAAACTAGCACCGGCTCACATTCTCCTAGAACACATCCTGCTGAACCCGCCGATTACGATCATCGCCCAAGATCTACAACTGGTGTTACTGAAGATGATAACAAAGAAACTTCCAGCGGTAGTGAACTTATTATGGATACGGACGACGTCGATCGAGAAGACGATCATCGCAGAGTGCCATCCCCTGAGTCTAACAGTGGTGATCTTGAGGCTGTGAAACGAATTCTAGAAACTGTGAATGCAACGGTGACAAAACAGTTATTGCAAGCCAACATGCAGAAACTGTCGACAGATTCGCCTAATAATAGTGATTGTCGTAGCGTTGCATCGCCAGCGTTATCGATAGAAGAAAAAATGCAATTCAATTGTAATGCGTGCAAGAAACAGTTTACTTCACACTCCGAGTTGAATTCGCATGATTGTGAGAACAGTGTTGAAATTAAAAGCGAAGGTTTAGCAGCCAAATTAGAAGAAGCTGTGCATGTAAAAAATGATGACGTTTCCATGAATGGTAATATGAGTGGTGGGGAAGACGATCATGATACGGATAGCAAACATAACGATAAATCCCACGATGACTACGACATTGACAACGAATCCGTCACGACAACTGACCACGTCGCTGAAGATGGACGAAAAGTTCGCGTGCGGTCCCTCATCGCGGACGAACAGTTGACAATTTTAAAAGATCACTACACAATGAACCCGCGACCAAAACGGGAAGAGTTGGCTCGTATTGCCGAGCGCATAGGTTTCCCGGTGCGAGTAGTTCAGGTCTGGTTCCAAAACACTCGAGCCAGAGATCGCCGTGAAGGGAGACTGGTACAAATTCCTTACAGCCCAATTCCTACCGCATCACTAGCATCTTGTTTTCCTCAGTCAATAGTGCCTTCCACCTCTCCGCACATAGCTCTTAGAACACTGCCGTACGGGCAGACCTCACCGCAGTACCAGAGTTCCGAGCAGCCACTAGACCTGTCCACGAAGAAGGGACCACTGTCGGTGACGTCGTCGCCGTCCAGTTCACCGCAGCGACCTGCTTCGGCAATCGCACACTCTGACTCCGGCGAGGAGGCCGTGAACCTCAGCCACAAGTCCTCCCGCAGCCCCACGCCTTTCCATCAGTTGCCTTATCAGCCCGTTCATTACCAGAGCTCAAACTGCTCGTCCGATTACCACCGTTCCCCGTCACCCGCGCCGCTTGCTTCGCTACCACTGCATCAAGATGCATTTACGAACGGCAGTCGTTTGGCAAGAATTCTAGCTCAGCCTGCTCATCGGCTTGCCATGGCTGGTGTTAGCTCCGCCATGGGCCTGCCCATGGACCGCCTACTGCAGTACAACCCAGACCTCCGTTCACCGCTCCTTAATGCTGCCAGTCCTAGTCCTAACTCCGAGAAACGGTCGTGGAAGATGGAGGATAATGACGACTCTGGTGTATCGCAGGAAATGTACACCGGCGACGATGATGTGTTATGTCAAACGAAGAAGAGCAAGATGGTACTACCGATGAAAAGTCTAAACAATGTGCTACTGACGCCTGGTGTTCCTGAACCCGAAATCGAAGGACAGTTTATCTGCGACCAATGTGACAAGGCGTTCTCCAAGCAAAGTTCTTTAGCACGTCACAAATATGAACACTCGGGTCAAAGACCACACAAATGCAACGAATGTCCAAAGGCATTCAAACACAAGCACCACCTGACGGAACACAAGCGATTACATAGTGGCGAGAAGCCGTTCCAGTGCTCCAAGTGTCTGAAGCGGTTCTCGCACTCAGGTTCGTACAGCCAGCATATGAACCACCGCTACTCCTACTGTAAGCCGTACAGAGAGTAA
Protein Sequence
MVARSESMFGCYDSYSYRLWSLANVWSTCHFPALTNGVSKDGEEAASADFIKCPQCQKGCGSFQALKEHIEVCHPHAVPEEASPAPLPPAAASAAASPPPTGPYACSQCTTSFSTKDQLEKHELLHSPNAQVSCKVCHKTFANVYRLQRHMISHDESAILRKFKCTECEKAFKFKHHLKEHIRIHSGEKPFECANCGKRFSHSGSYSSHMTSKKCLVMNLKMGRNRAASGANSLLDKSPSQASRGPKRPSVASLNNNITTSPNHNSYLPILPKYSEAAAAAFLSVMAPRDSAYPPPSSAAASLHPFYMTPPGLHLGAAAHPISPYTMSASLGQLLEQLQTSTGSHSPRTHPAEPADYDHRPRSTTGVTEDDNKETSSGSELIMDTDDVDREDDHRRVPSPESNSGDLEAVKRILETVNATVTKQLLQANMQKLSTDSPNNSDCRSVASPALSIEEKMQFNCNACKKQFTSHSELNSHDCENSVEIKSEGLAAKLEEAVHVKNDDVSMNGNMSGGEDDHDTDSKHNDKSHDDYDIDNESVTTTDHVAEDGRKVRVRSLIADEQLTILKDHYTMNPRPKREELARIAERIGFPVRVVQVWFQNTRARDRREGRLVQIPYSPIPTASLASCFPQSIVPSTSPHIALRTLPYGQTSPQYQSSEQPLDLSTKKGPLSVTSSPSSSPQRPASAIAHSDSGEEAVNLSHKSSRSPTPFHQLPYQPVHYQSSNCSSDYHRSPSPAPLASLPLHQDAFTNGSRLARILAQPAHRLAMAGVSSAMGLPMDRLLQYNPDLRSPLLNAASPSPNSEKRSWKMEDNDDSGVSQEMYTGDDDVLCQTKKSKMVLPMKSLNNVLLTPGVPEPEIEGQFICDQCDKAFSKQSSLARHKYEHSGQRPHKCNECPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE