Nbre002709.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nebria brevicollis
Gene Symbol
zfh1
Assembly
GCA_944739395.1
Location
CALYJC010000025.1:229744-237200[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.086 8 8.0 3.4 2 23 55 77 54 77 0.94
2 9 0.0002 0.019 16.3 0.7 3 23 109 129 107 129 0.95
3 9 4e-05 0.0038 18.5 1.8 2 23 136 157 135 157 0.97
4 9 6.9e-06 0.00064 20.9 5.9 1 23 166 188 166 188 0.99
5 9 8.5e-05 0.0079 17.5 1.0 1 21 194 214 194 215 0.95
6 9 1.2 1.1e+02 4.4 1.4 3 19 456 472 454 472 0.93
7 9 1.3e-05 0.0012 20.0 0.9 1 23 855 877 855 877 0.94
8 9 0.0002 0.019 16.3 9.4 1 23 883 905 883 905 0.98
9 9 0.0032 0.3 12.5 4.3 1 21 911 931 911 932 0.96

Sequence Information

Coding Sequence
ATGGTGGCACGTAGTGAAAGCATGTTTGGTTGCTACGACAGTTACTCGTACCGACTTTGGAGTCTGGCCAACGTTTGGAGCACCTGTCACTttCCCGCGTTGACCAACGGCGTTGCTTCTAAAGACGGCGACGAAGTGTCCGGTAACAGTGACCATTTCATCAAGTGTCCGCAATGCCAGCAAGGCTGTTCCACTTTTCAAACGCTTAAAGAGCACATCGAATTGTGTCACCCGCACGCCGTTCCCGAAGAGGGCAATACAGCGGCACTTCCACCGCTATCGTCACCACCTCCTGCAGCCGTCGGCACCGGTGGACCGTACGGATGTTCGCAGTGTTCTACCTCATTCAGCTCCAAGGATCAACTGGAGAAACACGAGCTTCTCCATTCACCTAATGCACAAGTTTCGTGTAAAGTGTGCCATAAAACTTTCGCCAACGTATACCGGCTACAGAGGCATATGATCAGTCACGATGAAAGTGCAATAttaagaaaattcaaatgCACCGAGTGCGAAAAAGCATTTAAATTCAAGCATCACTTAAAGGAACACATTCGTATTCACAGCGGAGAGAAGCCGTTCGAGTGTGGAAATTGTGGCAAACGATTCTCCCATTCCGGTTCCTATTCAAGTCATATGACATCGAAAAAGTGTCTAGTAATGAATCTTAAAATGGGCAGAAACCGAACGGCATCTGCATCGAATAGCCTTCTAGATAAAAGTCCCTCATCTAGAGCGCCGAAAAGACCATCGACATCACTAAACAATAACATCACTACTAGTCCGAATCATAACTCGTACTTGCCAATTTTACCCAAGTACAGTGAAGCAGCGGCCGCTTTCTTCTCGGTAATGGCGCCACGCGACGCTTCCTATCCCCCACCGACGTCTACGCCAGCATTACACCCATTCTACATGACGCCGCCGTTGCACTTGGGAGCCGCAACACACCCCATGAGTCCGTACACAATGTCTGCATCGTTAGGCCAACTTCTAGAACAATTACAAACTAATTCACCGCATCGGGCACAATCCACCGAATCCAACGATCAGGATAATCGATCGACGGTGACCATAACCGAAGACGACCAGAAAGCCACCTCAAGTTCCAGTGAACTAGTGATGGAAACCGACGATCCTGACAAGGATGACGAACAGCAGCCGCCGGGAAGGATTCCGTCGCCAGAATCGAACAGTGGCGACCTAGAAGCTGTGAAACGAATTTTAGAAACTGTAAATGCAACTGTTACAAAGCAACTATTGCAGGCCAACATGCAGAAATTATCGACAGATGATTCAGTCCACAGCGATTGCCGAAGTGTTACGTCACCCTTATCTGTCGATGAAAGGCTGAGCCAAGTGCATTGTAATTTGTGTAAAAAACTATTTGCTTCACACAAGGACTTGGATGTTCATGATTGTGAAACTAGTGTTAGAATTAAAAGCGAAGGTTTGGCCGCAAAGTTAGAAGATGCCGTTCATGTGAAAACGGAAGATGTCCATATGATGAATGGCAATATGAGCGGCTGTGAAGATGATACAGACAGCAAGCATAATGATAAAACACATGATGATTATGAAATCGACAACGAGTCCGTCACCACCACCGACCATGTATCTGAAGATGGACGTAAAGTTCGTGTCAGATCGCTGATTGCCGATGAGCAACTGACTATTTTAAAAGACCATTATTCCATGAATCCTAGGCCGAAGCGAGAAGAGTTGGCTCGCATCGCGGAACGTATTGGGTTTCCAGTGCGCGTAGTGCAAGTCTGGTTCCAAAACACAAGGGCGCGTGATCGTCGAGAAGGGAGATTGGTACAAATTCCTTACAGTCCTATTCCTACTGCAACAATAGCTTTTCCTCAGTCAATAGTGCCTTCCACTACCCCGCACATAGGACACAGAACTCTGCCGTCATACACAGGCCAAGCATCGCCGCAATACCAGAACCACAGTTCTGAACAACCACTGGATTTATCTACGAAAAAAGGACCGTTATCCGTAACATCGTCACCGTCCAGTTCTCCACAACGACCAACATCGGCGATTGCCCACTCTGACTCTGGCGAAGAGGCGGTCAATCTGAGTCACAAGTCCTCCCGTAGCCCGACGCCTTTCCATCAGTTGCCTTATCAACCTTATCACCAAAGTTCCAATGGTTCCTCCGATTACCATCGTTCCCCGTCGCCCGTACACTACCATCCCGATGCGTTTACGAACGGCAGCCGATTGGCAAGAATTCTCGCCCAGCCAGCGCACCGACTAACCATGGCTGGTGTTAGCTCTGCCATGGGCATTGTGCCAATGGAGCGGTTGCTGCAATACAATTCCGAACTCAAATCCCCTCTACTGAATACAGCCAGTTGTAGTCCGAACTCGGAACGCAGATCATGGAAGCTAGAAGATAACGAAGATTCGGGTGTGTCTCAGGAAATGTACGCCATGGATGAGGATATGCCGTGTCCAACGAAGAGAAGTAAAGTTTCTCAGTTGTCGTTGAAAGGGTTAAATACATCGCTTCTCGCAGCGAATGTTCCGGAACCAGAAATTGAGGGACAATTCATTTGTGAGCAATGCGACAAGGCGTTTTCTAAACAGAGTTCATTGGCTCGGCACAAATATGAACATTCAGgcCAAAGACCGCACAAATGTGATGAATGTCCGAAAGCCTTCAAACACAAGCATCACCTAACAGAACACAAGCGATTGCACAGTGGTGAGAAACCGTTCCAGTGTTCAAAGTGTTTGAAACGATTTTCGCATTCAGGTTCGTATAGTCAACACATGAACCACCGATACTCGTACTGTAAACCATACAGAGAGTAA
Protein Sequence
MVARSESMFGCYDSYSYRLWSLANVWSTCHFPALTNGVASKDGDEVSGNSDHFIKCPQCQQGCSTFQTLKEHIELCHPHAVPEEGNTAALPPLSSPPPAAVGTGGPYGCSQCSTSFSSKDQLEKHELLHSPNAQVSCKVCHKTFANVYRLQRHMISHDESAILRKFKCTECEKAFKFKHHLKEHIRIHSGEKPFECGNCGKRFSHSGSYSSHMTSKKCLVMNLKMGRNRTASASNSLLDKSPSSRAPKRPSTSLNNNITTSPNHNSYLPILPKYSEAAAAFFSVMAPRDASYPPPTSTPALHPFYMTPPLHLGAATHPMSPYTMSASLGQLLEQLQTNSPHRAQSTESNDQDNRSTVTITEDDQKATSSSSELVMETDDPDKDDEQQPPGRIPSPESNSGDLEAVKRILETVNATVTKQLLQANMQKLSTDDSVHSDCRSVTSPLSVDERLSQVHCNLCKKLFASHKDLDVHDCETSVRIKSEGLAAKLEDAVHVKTEDVHMMNGNMSGCEDDTDSKHNDKTHDDYEIDNESVTTTDHVSEDGRKVRVRSLIADEQLTILKDHYSMNPRPKREELARIAERIGFPVRVVQVWFQNTRARDRREGRLVQIPYSPIPTATIAFPQSIVPSTTPHIGHRTLPSYTGQASPQYQNHSSEQPLDLSTKKGPLSVTSSPSSSPQRPTSAIAHSDSGEEAVNLSHKSSRSPTPFHQLPYQPYHQSSNGSSDYHRSPSPVHYHPDAFTNGSRLARILAQPAHRLTMAGVSSAMGIVPMERLLQYNSELKSPLLNTASCSPNSERRSWKLEDNEDSGVSQEMYAMDEDMPCPTKRSKVSQLSLKGLNTSLLAANVPEPEIEGQFICEQCDKAFSKQSSLARHKYEHSGQRPHKCDECPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01275671;
90% Identity
iTF_01040011;
80% Identity
iTF_01039122;