Basic Information

Insect: Agonum fuliginosum
Gene Symbol: zfh1
Assembly: GCA_947534325.1
Location: OX384038.1:7361929-7370589[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.073 10 8.2 2.2 2 23 52 74 51 74 0.94

2 9 2.6e-05 0.0037 19.1 0.9 1 23 103 125 103 125 0.95

3 9 4e-05 0.0056 18.5 1.8 2 23 132 153 131 153 0.97

4 9 6.8e-06 0.00096 20.9 5.9 1 23 162 184 162 184 0.99

5 9 0.00012 0.017 17.0 0.9 1 21 190 210 190 211 0.95

6 9 0.04 5.6 9.1 1.1 2 20 456 474 455 476 0.91

7 9 1.3e-05 0.0019 20.0 0.9 1 23 855 877 855 877 0.94

8 9 0.0002 0.028 16.3 10.0 1 23 883 905 883 905 0.98

9 9 0.0031 0.44 12.5 4.3 1 21 911 931 911 932 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.073	10	8.2	2.2	2	23	52	74	51	74	0.94
2	9	2.6e-05	0.0037	19.1	0.9	1	23	103	125	103	125	0.95
3	9	4e-05	0.0056	18.5	1.8	2	23	132	153	131	153	0.97
4	9	6.8e-06	0.00096	20.9	5.9	1	23	162	184	162	184	0.99
5	9	0.00012	0.017	17.0	0.9	1	21	190	210	190	211	0.95
6	9	0.04	5.6	9.1	1.1	2	20	456	474	455	476	0.91
7	9	1.3e-05	0.0019	20.0	0.9	1	23	855	877	855	877	0.94
8	9	0.0002	0.028	16.3	10.0	1	23	883	905	883	905	0.98
9	9	0.0031	0.44	12.5	4.3	1	21	911	931	911	932	0.96

Sequence Information

Coding Sequence: ATGGTGGCACGTAGTGAGAGCATGTTCGGTTGCTACGACAGTTACAGTTACCGGCTTTGGAGTCTGGCCAACGTTTGGAGCACCTGTCACTTTCCCGCGCTGACGAACGGCGTGAAGAAAGAGGGCGAAGAAGCGAGCGACGGCGACTTCATCAAATGTCCGCAGTGTCAGAAGGGTTGCGGGACGTTCCAGGCGCTGAAGGAGCACATTGAGTTGTGCCACTCGCACGCCGTCCCCGAGGAAGCCAGTCCGGCGCCTCTGCCCCCGGCAGCTGCCTCTGCCGCCTCGCCGCCGCCCCCCGGGCCCTACGCCTGCTCCCAGTGCACCACTAGCTTCTCCACCAAGGATCAGTTGGAGAAGCACGAACTCCTGCATTCGCCGAATGCGCAAGTGTCCTGCAAAGTTTGCCATAAAACTTTTGCCAACGTTTACCGTCTGCAGCGGCACATGATTAGCCACGATGAAAGTGCCATCCTCCGAAAATTCAAATGCACAGAATGCGAAAAAGCATTCAAATTCAAACATCACTTAAAAGAACATATTCGCATTCACAGTGGAGAGAAACCATTCGAATGTGCAAACTGCGGGAAACGATTCTCGCACTCAGGTTCATATTCAAGTCATATGACATCGAAGAAATGTCTAGTTATGAACTTGAAGATGGGCCGAAACCGTGCGGCAAGCAGCGGTAATTCCCTTCTGGACAAAAATCAGTCTCAAGCGTCTCGAGGTTCGAAACGACCAAATGCTGCAGCACTTAACAACAACATCACCACTAGCCCCAATCACAATTCGTACTTGCCTATCTTGCCCAAATATAGTGAAGCAGCAGCAGCAGCGTTCTTATCCGTGATGGCTCCCAGAGACGGAGCTTACCCACCACCTTCTTCAGCCGCAACATTACATCCATTCTACATGACACCGCCAGGATTACACCTCGGTGCCGCTTCCCACCCCATCTCACCGTACGCAATGTCTGCATCCCTCGGACAACTCCTAGAACAACTTCAAACCAACGCTGGTTCGCATTCACCTAAAACCGACATAGCTGAAGACAACCGCTCCTTGACAGCGCCAGGTACCGCTGAAGATGACCACAAGGAAACTTCTAGTGGTAGCGAACTTGTCATGGACACAGATGAAGCCGATAGAGAAGAAGACAACCGAAGAGCACCGTCGCCCGAGTCCAACAGTGGTGATCTCGAGGCTGTGAAACGAATCCTAGAAACTGTGAATGCTACCGTGACAAAGCAGTTGTTGCAGGCCAACATGCAGAAACTGTCCACTGATTCTCCTAATAATAGTGAATCTCGTAGCATTGCATCGCCAGCGTTGTCAATAGACGATAAATTTCAAAATAATTTAAATTGTAATTGGTGCAAAAAACAGTTTACTTTGCAATCAGAGTTGGACTCGCATGAATGTGAGAACAGTGTTGAAATTAAAAGCGAAGGTTTAGCAGCCAAATTAGAAGAATCCGTGCATGTAAAAAATGAAGATGTTTCTATGAATGGTAACATGAGTGGTGGTGAAGATGACCATGATTCGGACAACAAACATAACGACAAATCGCACGATGACTATGACATTGACAATGAATCCGTCACAACAACTGACCATGTTGCTGAAGATGGTCGCAAAGTTCGCGTGCGTTCCCTAATAGCAGACGAGCAGTTAACTATTTTAAAAGACCATTACGCAATGAACCCGCGACCAAAACGTGAAGAATTAGCACGCATCGCTGAGCGCATAGGCTTCCCAGTGCGTGTCGTCCAAGTGTGGTTCCAAAACACACGAGCGCGTGATCGCCGAGAAGGGAGACTGGTACAGATTCCTTACAGCCCTATTCCTACCACTACACTAGCGCCTTTTCCTCAGTCAATAGTGCCTTCCACCCCTCCGCACATAGCTCTTAGAACATTGCCGTATGGTCAGACCTCGCCGCAATACCATAGCAGCTCGGAACAACCGTTAGACTTGTCCACAAAGAGAGAACCTCTGTCGGTGCCGACGTCGCCATCCAGTTCACCACAACGACCCGCGTCGGCCATCGCGCACTCGGATTCCGGTGAGGAAGCCGTCAACCTTAGCCACAAATCCTCCCGCAGCCCCACGCCTTTCCATCAGTTGCCTTATCAGCCAGTTCATTACCAGAGTTCCAACTGCTCATCCGACTACCACCGCTCTCCATCGCCAGCACCTCTCGCTTCCATGCCTCTGCACCAGGATGTATTTACGAATGGTAGTCGATTAGCTCGCATCTTGGCACAACCAGCACATCGTCTTGCCATGACATCTATGGGACTTCCCATGGAGCGCTTGTTACAATACAACCCAGATCTGCGGTCCCCACTTCTCAACACCGCAAGTCCTAGTCCTAACTCAGAGAAGAGGCCGTGGAAAATGGATGAAAATGAAGATTCGGGTGTTTCACAAGAGATGTACACTGGTGATGAAGATGTCATGTGTCCAACGAAGAAGAATAAAATGATCCTTTCAATGAAGAGCCTAAGTAACTCCATGTTGACACCTGGTGTTCCTGAACCTGAGATTGAGGGGCAATTCATCTGCGACCAGTGTGACAAAGCATTTTCTAAACAAAGCTCCTTGGCACGCCACAAGTATGAACATTCAGGTCAAAGACCGCACAAATGTAACGAATGTCCAAAGGCATTTAAACACAAACACCACCTGACGGAACACAAGCGGTTACACAGTGGAGAGAAGCCGTTCCAGTGCTCCAAGTGTTTGAAGCGATTTTCGCACTCAGGTTCGTACAGCCAACATATGAACCATCGCTACTCGTACTGTAAGCCGTATAGAGAGTAA
Protein Sequence: MVARSESMFGCYDSYSYRLWSLANVWSTCHFPALTNGVKKEGEEASDGDFIKCPQCQKGCGTFQALKEHIELCHSHAVPEEASPAPLPPAAASAASPPPPGPYACSQCTTSFSTKDQLEKHELLHSPNAQVSCKVCHKTFANVYRLQRHMISHDESAILRKFKCTECEKAFKFKHHLKEHIRIHSGEKPFECANCGKRFSHSGSYSSHMTSKKCLVMNLKMGRNRAASSGNSLLDKNQSQASRGSKRPNAAALNNNITTSPNHNSYLPILPKYSEAAAAAFLSVMAPRDGAYPPPSSAATLHPFYMTPPGLHLGAASHPISPYAMSASLGQLLEQLQTNAGSHSPKTDIAEDNRSLTAPGTAEDDHKETSSGSELVMDTDEADREEDNRRAPSPESNSGDLEAVKRILETVNATVTKQLLQANMQKLSTDSPNNSESRSIASPALSIDDKFQNNLNCNWCKKQFTLQSELDSHECENSVEIKSEGLAAKLEESVHVKNEDVSMNGNMSGGEDDHDSDNKHNDKSHDDYDIDNESVTTTDHVAEDGRKVRVRSLIADEQLTILKDHYAMNPRPKREELARIAERIGFPVRVVQVWFQNTRARDRREGRLVQIPYSPIPTTTLAPFPQSIVPSTPPHIALRTLPYGQTSPQYHSSSEQPLDLSTKREPLSVPTSPSSSPQRPASAIAHSDSGEEAVNLSHKSSRSPTPFHQLPYQPVHYQSSNCSSDYHRSPSPAPLASMPLHQDVFTNGSRLARILAQPAHRLAMTSMGLPMERLLQYNPDLRSPLLNTASPSPNSEKRPWKMDENEDSGVSQEMYTGDEDVMCPTKKNKMILSMKSLSNSMLTPGVPEPEIEGQFICDQCDKAFSKQSSLARHKYEHSGQRPHKCNECPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01275671;
90% Identity: iTF_00028597;
80% Identity: iTF_00028597;