Pnig050998.1
Basic Information
- Insect
- Pterostichus niger
- Gene Symbol
- LZTR1
- Assembly
- GCA_947425015.1
- Location
- OX380351.1:19032947-19054458[-]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 6.2e-10 4.9e-07 31.4 0.1 5 80 362 473 358 506 0.75 2 4 0.81 6.4e+02 2.1 0.0 77 109 506 538 496 539 0.84 3 4 6.5e-19 5.1e-16 60.3 0.0 8 95 601 688 595 704 0.85 4 4 0.33 2.6e+02 3.4 0.1 76 105 703 732 693 736 0.81
Sequence Information
- Coding Sequence
- ATGATTTTAGTGGATGCTAGCACCTCAAACGCTAGCCAAGTTTTCGACAATGGTTTGACACTTTATTTCGGACCTTTTGAAACGGTTCATCGATGGAAACGAATGCCAGAATGTGATGAATTTGTAGGTGCTAGGCGAAGCAAACACACAGTAGTCGCTTATAAAGAGGCTATTTACGTCTTTGGCGGTGACAATGGCAAGAGTATGTTAAATGATTTATTACGTTTTGACGTGAAGGAAAAGTCCTGGGGGCGGGCATTTGCAACTGGTTGCCCGCCGGCACCGAGGTATCATCATTCCGCAGTTGTTCACGGCACTTCAATGTTTGTTTTCGGTGGTTACACTGGTGATATACACTCGAATTCTAACCTAACAAACAAGAATGATTTGTTTGAGTATAAGTTTCATTCGGGACAGTGGGTTGAATGGAGGTTTTTGGGAAGGACTCCTGTACCGAGATCTGCTCATGGAGCTGCAGTTTTTGACGGGAAGTTATGGATATTTGCCGGATACGATGGTAATGCCAGATTGAATGATATGTGGACGATATCTTTGACAGGCGACACTCACAGCTGGGAGGAGGTGATGCAGAAAGGCGAATGTCCTCCAACATGCTGTAACTTCCCTGTCGCTGTTGCCAGGGAATGCATGTTTGTCTTCAGTGGCCAAAGTGGAGCCAAAATCACGAACTCCTTGTTCCAATTTAGTTTTAAGGAGAGATGCTGGATCCGCATCAGCACAGAACACATCCTGCGTGGTGCACCGCCCCCTCCTGCACGACGCTACGGACACACGATGGTGGCGCATGACCGCCACCTCTACGTGTTCGGTGGCGCAGCTGACAGCACGTTACCCAACGACCTCCACTGCTACGACTTGGATGCACGCGCATGGCACGTGGTGGCTCCTGCTGCAGACAGCCATGTGCCCAGTGGCAGGCTGTTTCACGCTGCTGCCGTCGTCCAGGATGCGATGTATGTGTTCGGAGGAACAGTGGATAATAATGTGCGGAGCGGGGAGATGTTTCGTTTTCAATTCTCCAGTTATCCCAAATGCACGCTGCACGATGACTACGGACGCATCCTGGAATCACGACAATTCTGTGACGTGGAGTTCATCGTCGGAGAGGACGAGGTTCGCATCCCAGCGCACATGGCTCTGGTGGCCGCGAGGTCACAGTGGCTACGCGCACGCATCCGGCAATCTCGTGAGCAGCGAGACAAGTTGCTGGAGAAACAACTCCAGGACAAGGAGAAAGATAAGGAGAAGGAAGGGAAGGAAGTCAAGGACGTGAAGGATATGCCCTTGGTGGAGGTAAAACTATTGGACGCAGTCCCCGAAGCCTTCCAGATGGTGCTAAACTACATCTACACCGACCGCATCGAGCCAACGCGCACCGGCAACGAGGACCCGTTCTCTAATCGCATCGTGCTGCTGATGATGGATGTGTACCGCCTCGCGGTGCAGTGTTGCATGCGACGTCTTGAAGCTCTGTGTGTCCAGTACCTCGAGGCCGCTGTTAGTTTACGGAACGTGCTGCAGGCGCTACATAATGCCGCGAGACTTCGTCTTGATTTTATTCAGGAGTTTTGTCTTCGATTTATCGTGAAAGATTCGAATTATAATCAGATTGTGATGTCTCGCGAATTCGAGACCCTGGAGCGCCAACTCATGGTGGACATTATCCGGCGGCGGCAAGTACCGACAGGACGCGCGCCCGAGCCTCGCTGTGAAGCCGCTGCTCCTGGACCTGGTGCCTCGCTCGAACAAGACCTGGCGCTGTTCCTCAAGTCCACTGGACACGATTTCTGTGACATCACCTTGCTGCTGGATGGACATGGTATCCCGGCACACAAGAGTGTGTTGGCTGCGCGGTGCGGTTACTTCGAGGCGATGTTTCGCTCGTTCATGCCGGTGGACAACACCGTCAGAATTCAGATCGGAGAAATGACGCCGAGTAGAGAAAGCTTCGATTCCTTGTTGAGATACATTTATTACGGAGACGTCTCAATGCCACCCGAAGACTCATTATATTTATTCTCGGCGCCATTTTTCTACGGCTTCACAAACAATCGTCTCCAAGCGTTCTGTAAACAAAATCTAGAAATGAACGTCACGTTTGAGAACGTTATTCAAATCCTAGAAGCTGCTGACAAAATGCAAGCGACAGACATGAAGAAATACGCGCTCAACATGATCGTTCATCACTTTTCCAAGGTGGCCCGGCTGGCGAAGATGCGCACTTTGAGCAGGGAATTAATTTTGGATGTGTTGGAGGCACTTGCTGATGACATGAGTGATAATAAAATGTGTCAGGATATGTCTTCTGTTAGTCTAAGCAGTGATTAA
- Protein Sequence
- MILVDASTSNASQVFDNGLTLYFGPFETVHRWKRMPECDEFVGARRSKHTVVAYKEAIYVFGGDNGKSMLNDLLRFDVKEKSWGRAFATGCPPAPRYHHSAVVHGTSMFVFGGYTGDIHSNSNLTNKNDLFEYKFHSGQWVEWRFLGRTPVPRSAHGAAVFDGKLWIFAGYDGNARLNDMWTISLTGDTHSWEEVMQKGECPPTCCNFPVAVARECMFVFSGQSGAKITNSLFQFSFKERCWIRISTEHILRGAPPPPARRYGHTMVAHDRHLYVFGGAADSTLPNDLHCYDLDARAWHVVAPAADSHVPSGRLFHAAAVVQDAMYVFGGTVDNNVRSGEMFRFQFSSYPKCTLHDDYGRILESRQFCDVEFIVGEDEVRIPAHMALVAARSQWLRARIRQSREQRDKLLEKQLQDKEKDKEKEGKEVKDVKDMPLVEVKLLDAVPEAFQMVLNYIYTDRIEPTRTGNEDPFSNRIVLLMMDVYRLAVQCCMRRLEALCVQYLEAAVSLRNVLQALHNAARLRLDFIQEFCLRFIVKDSNYNQIVMSREFETLERQLMVDIIRRRQVPTGRAPEPRCEAAAPGPGASLEQDLALFLKSTGHDFCDITLLLDGHGIPAHKSVLAARCGYFEAMFRSFMPVDNTVRIQIGEMTPSRESFDSLLRYIYYGDVSMPPEDSLYLFSAPFFYGFTNNRLQAFCKQNLEMNVTFENVIQILEAADKMQATDMKKYALNMIVHHFSKVARLAKMRTLSRELILDVLEALADDMSDNKMCQDMSSVSLSSD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01225929;
- 90% Identity
- iTF_00470057; iTF_01225929;
- 80% Identity
- -