Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.028 1.3e+02 3.2 0.1 26 51 121 146 112 147 0.85

2 5 0.0034 16 6.1 0.0 21 51 144 174 140 175 0.87

3 5 0.00016 0.73 10.4 0.1 22 44 173 195 168 203 0.87

4 5 0.025 1.2e+02 3.3 0.0 21 46 200 225 196 231 0.84

5 5 0.00018 0.84 10.2 0.1 21 47 228 254 223 260 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.028	1.3e+02	3.2	0.1	26	51	121	146	112	147	0.85
2	5	0.0034	16	6.1	0.0	21	51	144	174	140	175	0.87
3	5	0.00016	0.73	10.4	0.1	22	44	173	195	168	203	0.87
4	5	0.025	1.2e+02	3.3	0.0	21	46	200	225	196	231	0.84
5	5	0.00018	0.84	10.2	0.1	21	47	228	254	223	260	0.88

Coding Sequence: ATGACAAACGATCACCGTAAGCTTTCCACCGAGATAATGAATCTGAACGCTTCATTATGGATGGATAATCATATGATGATTATGCCAGAAGTAGTATTAAACGAAGACAAAAAAGACAAATGCGATAGTTACCCAGCCATCAACACATCAATAATTCTACAACCAGTAGAACTATTTGCACCATCGAAAACACTCGAGCTTCCCaaagaaactcaaattttcgatcatcATCTCTCCGATGCTGGCAAAATCAAACCCATTGGCGGGCCAGTATCGTGTACATGGTGTAAAATCGAATTCGCTGATAAGAACATCTTACTCGACCATATCAAACAAAACCATCGTGTAGATCGAGTTCACAAATGTCACCAGTGCTCTAAAATATTCACGCAGAAATCAAATCTAAAAGCCCATTACAGATTGCACACTGGCGAGAAACCATTCAAATGTACGTACTGTACGAAAACGTTCGCTCAAAAGTCTAACCTGATAAATCATCTATCTGTACATACGCGAGATAAACCATTCGAGTGCCCTATTTGTAAACGAGCTTTTTCTCAGAGATCTAATCTGAAAAGTCATATATTTACGCATACCGGTGAAAAACCATACAAATGTAATATGTGCAGTAAAGAATTTGTACAGAAATCAAATCTCGTCAGTCATGTGAGAACACATACTGCAGAAAAACCTCATAGATGTGATATTTGCGATAAATATTTTAGTCAGCGTTCCAATTTAATTagtcatttaaaattacacGCCAAAATGAATCCGacgtga
Protein Sequence: MTNDHRKLSTEIMNLNASLWMDNHMMIMPEVVLNEDKKDKCDSYPAINTSIILQPVELFAPSKTLELPKETQIFDHHLSDAGKIKPIGGPVSCTWCKIEFADKNILLDHIKQNHRVDRVHKCHQCSKIFTQKSNLKAHYRLHTGEKPFKCTYCTKTFAQKSNLINHLSVHTRDKPFECPICKRAFSQRSNLKSHIFTHTGEKPYKCNMCSKEFVQKSNLVSHVRTHTAEKPHRCDICDKYFSQRSNLISHLKLHAKMNPT

Sequence clustering based on sequence similarity using MMseqs2