Basic Information

Insect: Polyergus mexicanus
Gene Symbol: znf423
Assembly: GCA_030449975.1
Location: JAUDSZ010000022.1:2161875-2167067[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 6.7e-05 0.012 17.3 0.1 1 23 20 42 20 42 0.99

2 18 0.00026 0.045 15.5 1.1 1 23 208 231 208 231 0.97

3 18 0.75 1.3e+02 4.6 0.1 2 23 242 264 241 264 0.89

4 18 0.44 77 5.3 0.1 3 23 333 353 332 353 0.97

5 18 0.0048 0.84 11.5 0.4 3 23 370 390 368 390 0.95

6 18 0.0034 0.59 12.0 0.4 1 23 399 422 399 422 0.93

7 18 4 6.9e+02 2.3 0.2 1 23 427 450 427 450 0.91

8 18 3.1 5.4e+02 2.7 2.2 2 23 532 553 532 553 0.96

9 18 0.0055 0.96 11.3 0.1 1 23 558 581 558 582 0.94

10 18 3.5 6.2e+02 2.5 0.1 2 23 646 669 645 669 0.81

11 18 0.00013 0.023 16.4 0.9 2 23 687 709 686 709 0.96

12 18 0.48 84 5.2 2.6 1 23 718 741 718 741 0.92

13 18 0.99 1.7e+02 4.2 1.0 2 23 749 770 748 770 0.96

14 18 0.0022 0.39 12.6 0.1 2 23 938 960 937 960 0.96

15 18 0.15 26 6.9 0.2 1 23 972 995 972 995 0.95

16 18 0.28 49 6.0 0.2 2 23 1008 1029 1007 1029 0.95

17 18 0.38 66 5.6 0.2 2 23 1038 1060 1037 1060 0.93

18 18 0.0059 1 11.2 1.9 1 23 1067 1090 1067 1090 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	6.7e-05	0.012	17.3	0.1	1	23	20	42	20	42	0.99
2	18	0.00026	0.045	15.5	1.1	1	23	208	231	208	231	0.97
3	18	0.75	1.3e+02	4.6	0.1	2	23	242	264	241	264	0.89
4	18	0.44	77	5.3	0.1	3	23	333	353	332	353	0.97
5	18	0.0048	0.84	11.5	0.4	3	23	370	390	368	390	0.95
6	18	0.0034	0.59	12.0	0.4	1	23	399	422	399	422	0.93
7	18	4	6.9e+02	2.3	0.2	1	23	427	450	427	450	0.91
8	18	3.1	5.4e+02	2.7	2.2	2	23	532	553	532	553	0.96
9	18	0.0055	0.96	11.3	0.1	1	23	558	581	558	582	0.94
10	18	3.5	6.2e+02	2.5	0.1	2	23	646	669	645	669	0.81
11	18	0.00013	0.023	16.4	0.9	2	23	687	709	686	709	0.96
12	18	0.48	84	5.2	2.6	1	23	718	741	718	741	0.92
13	18	0.99	1.7e+02	4.2	1.0	2	23	749	770	748	770	0.96
14	18	0.0022	0.39	12.6	0.1	2	23	938	960	937	960	0.96
15	18	0.15	26	6.9	0.2	1	23	972	995	972	995	0.95
16	18	0.28	49	6.0	0.2	2	23	1008	1029	1007	1029	0.95
17	18	0.38	66	5.6	0.2	2	23	1038	1060	1037	1060	0.93
18	18	0.0059	1	11.2	1.9	1	23	1067	1090	1067	1090	0.97

Sequence Information

Coding Sequence: ATGATGCTACTCGATCATCTGAAGATCCACTTGAAAACGCATGACACCCAGAGGCCTTATCAATGCACGGCTTGCACAAGAGGTTACAGTACAGCCGCGGCTTTAACGGCGCACATGCAGTCTCACAAGAAACATcaatcatcgtcgtcgtctcAATCGGCCGGTCTCAAGCTTCAGGACGTCGACTACGGTAGAAGAAGCGTATCCTCGCACAGCACGTCATCACCGCCGGTaccgtcgtcgccgtcgccgtcatTGAATCTCAGTCTGAATCCAAGGAACGTCCCGAAGACGTCGCAGGGCAGCGGCAGCGCCTCCACCACTCCGATTCTCAGCTCGCCCCTGAAACTCGCCTGCATGTATTGCACCCGAGACTCGTTCAGCTGCATGCAGCAGCTGCAGATGCACGTGCACACGATGCACCAGGCGATCCTGAGCGGCGCGGAAGGTCCGGCTCGGCCGCCATCGCCGAGCAGAACATCCAGCGAGCAGCAGGCGACTGTCCGCAAGCCGCTGGATCGTCAGGACGTCACGAAGGAACCGCGGCTGGATCGCAAGTACCAGACGTCCGAGGATCGAGGCGACAGATCGGCTGTCGAGCGGGATCATTACGAGAACGGGTTCACTTGCAATCAGTGCACCATGAAGTTCTCTACGTTGACCCTCCTAcgcgatcatttgttgtcgatACACCGAATCGACGGTTTCGGCGCGGCGATGATGATGTGTCCCTTGTGCAGTATACCGTGTTCCTCGGCGGCTTCCTACGCCGAGCACTACGTTCTTCAGCACTGTGAGAATCGCCGATCAGCGCCGATGCACGCTACAGATTATGGGGAAACGAAGCTGAACGGCGGCATTTACGACGGTACCGCGAGGGATCCCTCCCGGATATCGAGAACTCGGGACGCGCCGGAAGCCGCTGATCTCACGAATAAGCACTCGACGAGATCTTCCTCGGATACCGCTGGCAGTTACACTGCTGATACTTTGCTATGCGGCCAATGCGGTGCCGCGTTAAAAGACTTCGAATCCTTCCGCGAGCATGTGGCGCGACACTTGCAAGCCGACCACCGTAACCAGGAGATGTCCGGCAGACAACATCTATGTCCCAAATGCGAAGCTATCTTCTCGGACCGCGAAGATATGCTAGCCCATTTGACCAAGCATTATCTGGGCCAAGTCAGCAAAGAATACGCCTGCAGTGCCTGCAAAAAGCTCTATCCGCATCCAGATCAGCTTCAGAGGCACCTTTTGGACGTGCACGCGCATCATCTGTATCGTTGCGCTCTGTGCCGGGATACCTTCGACTCCAGAGTAGCGATACAGGTGCATTTTGCGGTGAAGCACAGCCAGGAATGCCGGGTCTACCGGTGCAGCACGTGCGCCGTATCCAACAATGAGAACTCGCCGCCGGGAGGTAACGTGACGGCTTCTGGCGAAGGTAGGAGTTTCTTCAGGAGCGAAGCCGAAATGGCGGCGCACGTGCGTAATGTGCACGCGCCTCCACCCGCAATTTCTCTGATGAATAGCAGTCCAGTGGGTGCCACGAGGAGCCCGGCCTCGACGCCCGGTGGTGGTGGCATCGCGGCACGTTGTTTTTTCTGCGGGATCTGTTGCGGTTCAGATCTCGAACTCCAGCTTCATTTGGCCAGCCATTCGACCAATCTTTACAGATGTCCCATCTGCCGGGAAGGGTTCGCGGTGGAGTTTCTCTTGGACCGACACATCGCCCAGGCTCATCACGCGACCCAGGACCATCAGGTGGTGCCATCCGTTAGAAGTAACTCGAGAGAGAACGGACGCGTTCATCGAACGGCTAGAAATCAGGAAGACACGAAGTCTCTGAAGAGACGTTCACCAGCATCGAGTAACAACAATTCCCTGAATCAGCGTGACAACAACAAACGTGCAAACTATGGTACTTCCGCACAGCAGTGCGAGCTCTGCGAACGCGGCGAGTTTGCGAACGAGGCCGAGTTGCAGGCACACAAGAAACTGGCTCATCAAACGCCTCCTAAACTGTCCAGTAAAAGTCTATCTACCTTGAATACCTTGACGTGCGGTTATTGCGGCGAGGTTTGTCGTTCGCGAAACGAACTAGAGTCGCACACGAGGATCCAACATACGTCCAACGAGCCCGGCGGACGCCACAAGTGCAACATTTGCGACGAGGTATGCTTGTCCAGCACGACTTTGGCCGAACACAAGCTCCAGAAGCACTGCAAAATACAACTGAGCGACACGTGTGTGGTATGTCGTGGTTGCCTAACCTCGGAGAGTCAATTCCTGGATCACGTGCAAAGGCATAGCTTGGAAAACGTGGACCCGCAACAACGATTGGACAACTCTTTACCTCATTTACCAGCTCCGTGCGTTGTTTGCCGGCAGACGCTGATCAGCGAATTAGAGTGTCGTTTGCATGCGCGGCATCATCTACGCGCGACATCTTCGGGATCGCGCAGCGCCGTTTCTAGTCCAAACAGTCCCGGTGGCGGCAAAACTCAGAGCCAAGGTTGCTGTCTTTGTTTGCGCGATTTTGCTGCCGATGATTTCGTCAGCTTGCCACCCAATCCTGCCAGTACGAGTGGACAACCACTCAAGGTCTGCAAAACCTGTTACATACGACACTCTCAGGGATTGCCTATCCTGAACTCGACGACTTATGAGCGAGCCAAGTACGACACGACCTGGTTTGCAAGCAAGAATGGTCAATGGGATAGTTCCAAGGACAAGTGGAATGACAGAGGACTCAAGGAAAATCGATCCATGGAGAATCGATCCAGAAATGAAGGAAACCCGGATAAAAAACGCTGTGAGGAATGCGGAGTGAAGTTCGAAGATCCCGAAGAGGCGGAAAAACACAGAATCACAGAACATGAAAAGATTAGCATTAGTGGTTCGAAACCCTCCTATACATGTATACAGTGTCAGGTATCATTTCCAACCGAAGCCAAAATTCAGCAACATGTAAGAAAAGAACATCTGGAAACATCCAGGAGAGCTTCCCTAGAAGCCTTGCGATGTCATTTGTGCTCATTTGAAGCTGCCAGTCCTATGCAACTGCAAATTCATTTAATAGAACATACTTTTGTTGGCTGCGCTGCGCTCAGCTGTTATCTCTGTCAGTCGCTCTTCACAACTCCTATTGGTCTTCAGAGTCACCTGCTACAGGAACACGGTCTGGGCGCGCGACCGTACGATTGCCCCAAATGCACGCTCAAGTTCTTCTTCAACGCGGAGCTAGACCACCACATATTGACCTTTCATCGTCCGAGGAATGAGATTCATGCTTCGGCAGTCGAGAATGCTCGCGAGATGAAGAACCGCGAGCCCGACGGTGGTGTAACAGTGAAGGAGGAAGTGATACAAGGTGGTaaagaagaggaggaggaggaggaggaggaagaggaagaagaagtgAACGTGGACGACCAGATAGGACAGGAGGAACAGGATGAAGCTAAACGAGAGGAACAGGAATTGAAGACAGAAGTAGATATCGAGACGACATCCAATAAAATGGAATCGTGA
Protein Sequence: MMLLDHLKIHLKTHDTQRPYQCTACTRGYSTAAALTAHMQSHKKHQSSSSSQSAGLKLQDVDYGRRSVSSHSTSSPPVPSSPSPSLNLSLNPRNVPKTSQGSGSASTTPILSSPLKLACMYCTRDSFSCMQQLQMHVHTMHQAILSGAEGPARPPSPSRTSSEQQATVRKPLDRQDVTKEPRLDRKYQTSEDRGDRSAVERDHYENGFTCNQCTMKFSTLTLLRDHLLSIHRIDGFGAAMMMCPLCSIPCSSAASYAEHYVLQHCENRRSAPMHATDYGETKLNGGIYDGTARDPSRISRTRDAPEAADLTNKHSTRSSSDTAGSYTADTLLCGQCGAALKDFESFREHVARHLQADHRNQEMSGRQHLCPKCEAIFSDREDMLAHLTKHYLGQVSKEYACSACKKLYPHPDQLQRHLLDVHAHHLYRCALCRDTFDSRVAIQVHFAVKHSQECRVYRCSTCAVSNNENSPPGGNVTASGEGRSFFRSEAEMAAHVRNVHAPPPAISLMNSSPVGATRSPASTPGGGGIAARCFFCGICCGSDLELQLHLASHSTNLYRCPICREGFAVEFLLDRHIAQAHHATQDHQVVPSVRSNSRENGRVHRTARNQEDTKSLKRRSPASSNNNSLNQRDNNKRANYGTSAQQCELCERGEFANEAELQAHKKLAHQTPPKLSSKSLSTLNTLTCGYCGEVCRSRNELESHTRIQHTSNEPGGRHKCNICDEVCLSSTTLAEHKLQKHCKIQLSDTCVVCRGCLTSESQFLDHVQRHSLENVDPQQRLDNSLPHLPAPCVVCRQTLISELECRLHARHHLRATSSGSRSAVSSPNSPGGGKTQSQGCCLCLRDFAADDFVSLPPNPASTSGQPLKVCKTCYIRHSQGLPILNSTTYERAKYDTTWFASKNGQWDSSKDKWNDRGLKENRSMENRSRNEGNPDKKRCEECGVKFEDPEEAEKHRITEHEKISISGSKPSYTCIQCQVSFPTEAKIQQHVRKEHLETSRRASLEALRCHLCSFEAASPMQLQIHLIEHTFVGCAALSCYLCQSLFTTPIGLQSHLLQEHGLGARPYDCPKCTLKFFFNAELDHHILTFHRPRNEIHASAVENAREMKNREPDGGVTVKEEVIQGGKEEEEEEEEEEEEEVNVDDQIGQEEQDEAKREEQELKTEVDIETTSNKMES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01406753;
90% Identity: iTF_00868309;
80% Identity: -