Pmex036522.1
Basic Information
- Insect
- Polyergus mexicanus
- Gene Symbol
- Zeb1
- Assembly
- GCA_030449975.1
- Location
- JAUDSZ010000025.1:115834-118487[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.029 5.1 9.0 0.6 1 23 353 376 353 376 0.91 2 14 4.6e-05 0.0081 17.9 1.4 1 23 382 404 382 404 0.98 3 14 0.1 17 7.4 5.3 1 23 488 510 488 510 0.93 4 14 0.0046 0.81 11.6 0.4 1 23 517 540 517 540 0.91 5 14 0.00074 0.13 14.1 4.4 1 23 546 568 546 568 0.97 6 14 0.0011 0.19 13.5 2.2 1 23 574 596 574 596 0.99 7 14 1.5e-06 0.00025 22.6 1.2 1 23 602 624 602 624 0.98 8 14 0.0082 1.4 10.8 0.3 1 23 637 660 637 660 0.96 9 14 0.00013 0.022 16.5 4.3 1 23 676 699 676 699 0.96 10 14 0.00031 0.055 15.2 0.5 1 23 707 730 707 730 0.98 11 14 3e-05 0.0052 18.5 0.5 1 23 736 758 736 758 0.98 12 14 0.0036 0.64 11.9 8.5 1 23 764 786 764 786 0.98 13 14 3.2e-05 0.0056 18.4 3.0 1 23 792 815 792 815 0.98 14 14 0.00068 0.12 14.2 0.5 2 23 821 842 820 842 0.97
Sequence Information
- Coding Sequence
- atgtcaaatgaTTCATTGATATGTCGTTTGTGTGGTATTAAGCATGAACTcacaaattcaaaatatatctttgatGAGGCAACTAATTTAACTCGGAAAATAAATGACACGCTACCAATCAGGATTTCGCAGGACGATCATTCCAAATACATATGCTTGGACTGTTACGGTAGAGTTACTACTCATTATGATTTTATCCAAAATgtattgaaaaattcaaagaaaaaCGTTAATATGGCAAAAAGTAATTCTTCATTTGAGCCcaataaaagtgaaaaaatgGAAATTGCAGCAATTTCCAAACTATATAatgatatgatatatacatgCCCAAATTGCAATATAGATTTAATGATACTAATAAAAAGCAATCCTGATGATTGTAATTACGCATTTCAAATTTCATTGGCCATGGTAGACCAAATGGAAAAATCAATGGATAGAAATATCCAAACCTGTGATGATGCAATAGAATTTGTTAATACTTGCATAAAAACATCAAGTACAGAAGATGATTTAGATCAGAGTATTATCAACGATACATTGGATGATAAGGAACAAAACATCAACAAAACAGATGAGAAGTTACCAATATTACAAGAAGATATAAATCATGTTGGCACTTGCGTtacatttcaaaaaaataatatatcgcatCGATCGAGCAAAGGTACAAAAAGAAAACTaaaggaaaatatttcttgcgGAACACCTACTAAATCACAAAAACTAGAAACGAAATTAGATGCAACAGGCACTAATGTATTGGATAATGATTATGGGTGTGTAGATATCTTGATAAAAGATGAGAATCTAAATGATGGAATAGATGAAGGTATCGAATGGCTTAGCGGCGAAGTAAACTTCAAAGAAGAGAATACTACAGTGTATACAATGGAAGTCGAAAAAGATGACATTGATGAAAATGGTATAAAATACGACGATATCGACAATAAGAGTccaaaaattgtatgtaatTTATGTGGAGCTCGTTATCTTTCACAATTAAAATACGAGTTTCACATGGAGAGGCACAAGTCAAACAAAATGGATAGATATGTCTGCACAGTATGCGACAAAGAAGCTAGCagtgaaaatttattatgggATCACTATTTCCATACGCATAAAAGCTCGATGCGGTATGCGTGCACGCAATGCGGCAAGATGTTTACGAAGAAACCGAGATTAAATGGCCACCAAAAGAGACATAAACACTTTGGTATCAAAGAGATACATTTTGAGACGGGCATGGATGAAACGAGCGTCAATCAGGCACAGAAAGCTATCGCGGTCGAAATACAAGGACGAGTTGCCGCAAATTGTAGTCTCTGTGGAAAATTAATAACAGATTTAGATCCGGATGCCATCAACGATTTGGCGACATGCGCGGCCTGCGAGGATTCCACTTTATCGCTGATGGTCGATGGAAACGAAATGAAAGTGATCTCACCGCGGCAGTACCATTGCTCAAAATGCCCTAAACATTTTGTACGCAAGGAGAGATTGGAATTTCATGAGATGAGACATAATGAAAACATGAATGAATTTATCTGCAGCACATGCGGCAAGGAGTTTAGCGCAGAAAACTCCTTATATGAGCATTATCTCTTTGTACACAAAGGGGCTAGACCGCATATCTGTGAGCAATGTGGCAAGTCGTTTCAGTTGAAGGCACGATTGAAGGAACATCATCGCACGCATACAGGCGAGAGACCTTATCAATGTGACGTATGCGGCCTACGTTGCATGACTACCAACGCGCTCAAACTCCACAGGAAAACTCATTTCTCCTACAATCGCTACGTTTGTAATATATGCGACAAGTCCTTCAGCAAAAAACAGAACATGAACGAGCATTTAGAAAAGCACTGGAAAAACGATAAGAATGTATCGCTGCCGCAATTGTTTACATGTCCGGTATGTACCGAAGATCTGCCGACCTATCGTATGCTAAAGTATCACATGATGGAGACTCATCAAATCAACCACCAAGATCCCTTACTAACAACACAAAAACCATGGTACGAATGCAACGAGTGTCATGAAAAGTTCAAACATCAAATGTCGTTGAAGGCGCACAAAGAAAAGGTACACGAGGGTAAGGTCAGCCCGATATTCCAGTGCGATATATGCAATGCTACTTACAGAATCAAGCAGCTGCTAATAAATCACATCAAAAGCAAGCATGGCGGTGAGAAGCGATACAAATGTGCGCAATGTGGCAAAGGATTCAATGATACCAAATCCTTGTACAATCACATTTTATTACACACTGGTAGGAAGCCGTTCACTTGTGAATACTGTCACATGAGCTTCAGGCGAAAAGACTCCAGGGACCACCATCGCCGTAAGCATACAGGCGAACAACCTTACCAGTGCTCGGATTGCGGACAATCGTTTTCTACCTACAACAATCGCTCAAAGCATCGCAAGAAGGAACACGGAGAAGGTGAAATCGAATGTCCGGAATGTGGAGAAAAATGTAACAGTCAACAAGAAATCAGAATTCATCTGAACAAGCATCTTGGTGAAAAATTGAATAACTTGCAACGTGTATAA
- Protein Sequence
- MSNDSLICRLCGIKHELTNSKYIFDEATNLTRKINDTLPIRISQDDHSKYICLDCYGRVTTHYDFIQNVLKNSKKNVNMAKSNSSFEPNKSEKMEIAAISKLYNDMIYTCPNCNIDLMILIKSNPDDCNYAFQISLAMVDQMEKSMDRNIQTCDDAIEFVNTCIKTSSTEDDLDQSIINDTLDDKEQNINKTDEKLPILQEDINHVGTCVTFQKNNISHRSSKGTKRKLKENISCGTPTKSQKLETKLDATGTNVLDNDYGCVDILIKDENLNDGIDEGIEWLSGEVNFKEENTTVYTMEVEKDDIDENGIKYDDIDNKSPKIVCNLCGARYLSQLKYEFHMERHKSNKMDRYVCTVCDKEASSENLLWDHYFHTHKSSMRYACTQCGKMFTKKPRLNGHQKRHKHFGIKEIHFETGMDETSVNQAQKAIAVEIQGRVAANCSLCGKLITDLDPDAINDLATCAACEDSTLSLMVDGNEMKVISPRQYHCSKCPKHFVRKERLEFHEMRHNENMNEFICSTCGKEFSAENSLYEHYLFVHKGARPHICEQCGKSFQLKARLKEHHRTHTGERPYQCDVCGLRCMTTNALKLHRKTHFSYNRYVCNICDKSFSKKQNMNEHLEKHWKNDKNVSLPQLFTCPVCTEDLPTYRMLKYHMMETHQINHQDPLLTTQKPWYECNECHEKFKHQMSLKAHKEKVHEGKVSPIFQCDICNATYRIKQLLINHIKSKHGGEKRYKCAQCGKGFNDTKSLYNHILLHTGRKPFTCEYCHMSFRRKDSRDHHRRKHTGEQPYQCSDCGQSFSTYNNRSKHRKKEHGEGEIECPECGEKCNSQQEIRIHLNKHLGEKLNNLQRV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00869094;
- 90% Identity
- iTF_00730964; iTF_00729540; iTF_00730252; iTF_00280144;
- 80% Identity
- -