Fase004375.1
Basic Information
- Insect
- Formica aserva
- Gene Symbol
- Zeb1
- Assembly
- GCA_037039905.1
- Location
- JAXRKO010000003.1:5044308-5046976[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 9.2 1.8e+03 1.2 0.2 1 16 50 65 50 67 0.88 2 15 0.029 5.8 9.0 0.6 1 23 358 381 358 381 0.91 3 15 4.6e-05 0.0091 17.9 1.4 1 23 387 409 387 409 0.98 4 15 0.098 20 7.4 5.3 1 23 493 515 493 515 0.93 5 15 0.0046 0.91 11.6 0.4 1 23 522 545 522 545 0.91 6 15 0.00073 0.15 14.1 4.4 1 23 551 573 551 573 0.97 7 15 0.0011 0.22 13.5 2.2 1 23 579 601 579 601 0.99 8 15 1.4e-06 0.00029 22.6 1.2 1 23 607 629 607 629 0.98 9 15 0.071 14 7.8 0.2 1 23 642 665 642 665 0.93 10 15 0.00013 0.025 16.5 4.3 1 23 681 704 681 704 0.96 11 15 0.00031 0.062 15.2 0.5 1 23 712 735 712 735 0.98 12 15 2.9e-05 0.0058 18.5 0.5 1 23 741 763 741 763 0.98 13 15 0.0036 0.72 11.9 8.5 1 23 769 791 769 791 0.98 14 15 3.1e-05 0.0063 18.4 3.0 1 23 797 820 797 820 0.98 15 15 0.00067 0.13 14.2 0.5 2 23 826 847 825 847 0.97
Sequence Information
- Coding Sequence
- atgtcaaatgATTCATTGATATGTCGTTTGTGTGGTATTAAACATGAACTtacaaattcaaaatatatctttgatgAGGCAACTAATTtaactcaaaaaataaatgacaCACTACCAATCAGGATTTCGCAGGATGATCATTCCAAATACATATGCTTGGACTGCTATGAAAAAGTTACTACTCATTATGATTTTATCCAAAATGTATTGGAAAATTCAAAGGAGAACGTTAATATGGCAAAAAGTAATTCTTCATTTGAGCCcaataaaagtgaaaaaatggaaattgCAGCAATTTCCAAACTATATAATGATATGATATATACATGCCCAAATTGCAATATAGATTTAATGATACTAATAAAAAGCAATCCTGATGATTGTAATTATGCATTTCAAATTTCATTGGCCATAGTAGACCAAATGGAAAAATCAATGGAAAGAAATATCCAAACCTGTGATGATGCAATAGAATTTGTTAATACTTGCATAAAAACATCAAGTATAGAAGATGATTTGCATGAATCATCATTGAATCAGAGTATTATCAACGATACATTGAATGATAAGGAACagaacataaataaaacagatGAAAAGTTACTAATACTACAAGAAGATATAAATCATGTTGACACTTGCATtacatttcaaaaaaataatgtatcacATCGATTGAGCAAAGGTACAAAAAGAAAACTTaaggaaaatatttcttgcgaAACACCTACTAAATCACAAAAACTAGAAACGAAATTAGATGCAACAGACACTAATGTATTGGACAATGATTATGGGTGTGTAGATATCTTGATAAAAGATGAGAATCTAAATGATGGAATAGATGAAGGTGTCGAATGGCTTAGTGGTGAAATAAACTTCAAAGAAGAGAATACTACAGTGTATACAATAGAAGCTGAAAAAGATCACATTGATGAAAATGGTATAAAATACGACGATATCGACAATAAGAGTccaaaaattgtatgtaatTTATGTGGAGCTCGTTATCTTTCTCAATTAAAATACGAGTTTCACATGGAGAGGCACAAGTCAAACAAAATGGATAGATATGTCTGCACAGTATGTGACAAAGAAGCTAGCAGTGAGAACTTATTGTGGGATCACTATTTCCATACACATAAAAGCTCGATGCGGTATGCTTGCACACAATGCGGCAAGATGTTTACGAAGAAACCGAGATTAAATGGCCACCAAAAGAGACATAAACACTTTGGTATCAAAGAGATACATTTTGAGATGGGCATGGATGAAATAAGCGTCAATCAAGCACAGAAAGCTATCGCGGTCGAAATACAAGGACGAGTTGCCGCAAATTGTAGTCTCTGTGGaaaattaataacagattTAGATCCGGATGCTATCAACGATTTGGCGACATGCGCGGCCTGCGAGGATTCCACTTTATCGCTGATGGTCGATGGAAACGAAATGAAAGTGATCTCGCCGCGGCAGTACCATTGCTCAAAATGCCCTAAACATTTTGTGCGCAAAGAGAGATTGGAGTTTCATGAGATGAGACATAATGAAAACATGAACGAATTTATCTGCAGCACATGTGGCAAGGAGTTTAGTGCAGAAAACTCCTTGTATGAGCATTATCTCTTTGTACACAAAGGAGCTAGGCCACATATCTGTGAGCAGTGCGGCAAGTCGTTTCAGTTGAAGGCACGATTGAAAGAACATCATCGCACGCATACAGGTGAAAGACCTTATCAATGCGACGTATGCGGTCTACGCTGCATGACTACCAATGCGCTCAAACTCCACAGGAAAACTCATTTCTCTCACAATCGCTATGTTTGTAATATATGTGACAAATCCTTCAGCAAAAAACAGAACATGAACGAGCATTTGGAAAAGCACTGGAAAAACGATAAGAATGTATCGCTGCCGCAATTGTTTACATGTCCGGTATGTACCGAAGATCTGCCGACCTATCGTATGCTAAAGTATCACTTGATCGACACTCATAAGCTCGATCGCCAAGATCCCTTACTATCAACACAAAAACCATGGTACGAATGCAACGAATGTCATGAAAAGTTCAAACATCAAATGTCGCTGAAGGCGCACAAAGAAAAAGTACACGAGGGTAAGGTCAGCCCAATATTCCAGTGCGATATATGTAACGCTACTTACAGAATCAAGCAGCTGCTGATAAATCACATCAAAAGCAAGCATGGTGGTGAAAAGCGATACAAATGTGCGCAATGTGGCAAAGGATTCAATGATACCAAATCCTTGTACAATCACATTTTATTACACACTGGTAGGAAGCCATTCACTTGTGAATACTGTCACATGAGCTTCAGGCGAAAAGACTCCAGGGACCACCATCGCCGTAAGCATACAGGCGAACAGCCTTACCAGTGCTCGGATTGCGGACAATCGTTTTCTACCTACAACAATCGCTCAAAGCATCGCAAGAAGGAACATGGAGAAGGTGAAATCGAATGTCCAGAGTGTGGAGAAAAATGTAACAGTCAACAAGAAATCAGAATTCATCTGAACAAGCATCTTGGTGAAAAATTGAATAACTTACAACGTGTATAA
- Protein Sequence
- MSNDSLICRLCGIKHELTNSKYIFDEATNLTQKINDTLPIRISQDDHSKYICLDCYEKVTTHYDFIQNVLENSKENVNMAKSNSSFEPNKSEKMEIAAISKLYNDMIYTCPNCNIDLMILIKSNPDDCNYAFQISLAIVDQMEKSMERNIQTCDDAIEFVNTCIKTSSIEDDLHESSLNQSIINDTLNDKEQNINKTDEKLLILQEDINHVDTCITFQKNNVSHRLSKGTKRKLKENISCETPTKSQKLETKLDATDTNVLDNDYGCVDILIKDENLNDGIDEGVEWLSGEINFKEENTTVYTIEAEKDHIDENGIKYDDIDNKSPKIVCNLCGARYLSQLKYEFHMERHKSNKMDRYVCTVCDKEASSENLLWDHYFHTHKSSMRYACTQCGKMFTKKPRLNGHQKRHKHFGIKEIHFEMGMDEISVNQAQKAIAVEIQGRVAANCSLCGKLITDLDPDAINDLATCAACEDSTLSLMVDGNEMKVISPRQYHCSKCPKHFVRKERLEFHEMRHNENMNEFICSTCGKEFSAENSLYEHYLFVHKGARPHICEQCGKSFQLKARLKEHHRTHTGERPYQCDVCGLRCMTTNALKLHRKTHFSHNRYVCNICDKSFSKKQNMNEHLEKHWKNDKNVSLPQLFTCPVCTEDLPTYRMLKYHLIDTHKLDRQDPLLSTQKPWYECNECHEKFKHQMSLKAHKEKVHEGKVSPIFQCDICNATYRIKQLLINHIKSKHGGEKRYKCAQCGKGFNDTKSLYNHILLHTGRKPFTCEYCHMSFRRKDSRDHHRRKHTGEQPYQCSDCGQSFSTYNNRSKHRKKEHGEGEIECPECGEKCNSQQEIRIHLNKHLGEKLNNLQRV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00869094;
- 90% Identity
- iTF_01245406;
- 80% Identity
- -